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Information on EC 5.5.1.23 - aklanonic acid methyl ester cyclase

for references in articles please use BRENDA:EC5.5.1.23

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IUBMB Comments

The enzyme is involved in the biosynthesis of aklaviketone, an intermediate in the biosynthetic pathways leading to formation of several anthracycline antibiotics, including aclacinomycin, daunorubicin and doxorubicin.

The expected taxonomic range for this enzyme is: Bacteria, Archaea
  • 5.5.1.23
  • desaturase
  • arachidonic
  • delta6-desaturase
  • polyunsaturated
  • delta5
  • alpha-linolenic
  • b5-like
  • histidine-rich
  • di-homo-gamma-linolenic
  • daunomycin
  • desaturation
  • alpina
  • oleic
  • delta5-desaturation
  • polyketide
  • mortierella

Synonyms
aklanonic acid methyl ester cyclase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
aklaviketone = methyl aklanonate
show the reaction diagram
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