Information on EC 5.5.1.16 - halimadienyl-diphosphate synthase

for references in articles please use BRENDA:EC5.5.1.16
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IUBMB Comments
Requires Mg2+ for activity. This enzyme is found in pathogenic prokaryotes such as Mycobacterium tuberculosis but not in non-pathogens such as Mycobacterium smegmatis so may play a role in pathogenicity. The product of the reaction is subsequently dephosphorylated yielding tuberculosinol (halima-5,13-dien-15-ol).
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The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
CPS4:H501, HPS, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
geranylgeranyl diphosphate = tuberculosinyl diphosphate
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PATHWAY SOURCE
PATHWAYS
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