Reference on EC 5.4.99.B22 - multisite-specific tRNA pseudouridine synthase
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Motorin, Y.; Keith, G.; Simon, C; Foiret, D.; Simos, G.; Hurt, E.; Grosjean, H.
The yeast tRNA: pseudouridine synthase Pus1p displays a multisite substrate specificity
RNA
4
856-869
1998
Saccharomyces cerevisiae (Q12211), Saccharomyces cerevisiae
Arluison, V.; Hountondji, C.; Robert, B.; Grosjean, H.
Transfer RNA-Pseudouridine Synthetase Pus1 of Saccharomyces cerevisiae contains one atom of zinc essential for its native conformation and tRNA recognition
Biochemistry
37
7268-7276
1998
Saccharomyces cerevisiae (Q12211)
Chen, J.; Patton, J.R.
Cloning and characterization of a mammalian pseudouridine synthase
RNA
5
409-419
1999
Mus musculus (Q9WU56), Mus musculus
Arluison, V.; Buckle, M.; Grosjean, H.
Pseudouridine synthetase Pus1 of Saccharomyces cerevisiae: kinetic characterisation, tRNA structural requirement and real-time analysis of its complex with tRNA
J. Mol. Biol.
289
491-502
1999
Saccharomyces cerevisiae (Q12211)
Arluison, V.; Batelier, G.; Ris-Kautt, M.; Grosjean, H.
RNA: pseudouridine synthase pus1 from Saccharomyces cerevisiae: oligomerization property and stoichiometry of the complex with yeast tRNA Phe
Biochimie
81
751-756
1999
Saccharomyces cerevisiae (Q12211)
Bykhovskaya, Y.; Casas, K.; Mengesha, E.; Inbal, A.; Fischel-Ghodsian, N.
Missense mutation in pseudouridine synthase 1 (PUS1) causes mitochondrial myopathy and sideroblastic anemia (MLASA)
Am. J. Hum. Genet.
74
1303-1308
2004
Homo sapiens (Q9Y606), Homo sapiens
Behm-Ansmant, I.; Massenet, S.; Immel, F.; Patton, J.R.; Motorin, Y.; Branlant, C.
A previously unidentified activity of yeast and mouse RNA:pseudouridine synthases 1 (Pus1p) on tRNAs
RNA
12
1583-1593
2006
Mus musculus, Saccharomyces cerevisiae (Q12211), Saccharomyces cerevisiae
Sibert, B.S.; Fischel-Ghodsian, N.; Patton, J.R.
Partial activity is seen with many substitutions of highly conserved active site residues in human Pseudouridine synthase 1
RNA
14
1895-1906
2008
Homo sapiens (Q9Y606), Homo sapiens
Simos, G.; Tekotte, H.; Grosjean, H.; Segref, A.; Sharma, K.; Tollervey, D.; Hurt, E.C.
Nuclear pore proteins are involved in the biogenesis of functional tRNA
EMBO J.
15
2270-2284
1996
Saccharomyces cerevisiae (Q12211)
Hellmuth, K.; Grosjean, H.; Motorin, Y.; Deinert, K.; Hurt, E.; Simos, G.
Cloning and characterization of the Schizosaccharomyces pombe tRNA:pseudouridine synthase Pus1p
Nucleic Acids Res.
28
4604-4610
2000
Schizosaccharomyces pombe (O94396), Schizosaccharomyces pombe
Schwartz, S.; Bernstein, D.A.; Mumbach, M.R.; Jovanovic, M.; Herbst, R.H.; Leon-Ricardo, B.X.; Engreitz, J.M.; Guttman, M.; Satija, R.; Lander, E.S.; Fink, G.; Regev, A.
Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation of ncRNA and mRNA
Cell
159
148-162
2014
Saccharomyces cerevisiae (Q08647)
Lu, S.; Li, C.; Zhang, Y.; Zheng, Z.; Liu, D.
Functional disruption of a chloroplast pseudouridine synthase desensitizes Arabidopsis plants to phosphate starvation
Front. Plant Sci.
8
1421
2017
Arabidopsis thaliana (Q8L960)
Zaganelli, S.; Rebelo-Guiomar, P.; Maundrell, K.; Rozanska, A.; Pierredon, S.; Powell, C.A.; Jourdain, A.A.; Hulo, N.; Lightowlers, R.N.; Chrzanowska-Lightowlers, Z.M.; Minczuk, M.; Martinou, J.C.
The pseudouridine synthase RPUSD4 is an essential component of mitochondrial RNA granules
J. Biol. Chem.
292
4519-4532
2017
Homo sapiens (Q96CM3)
Tillault, A.S.; Schultz, S.K.; Wieden, H.J.; Kothe, U.
Molecular determinants for 23S rRNA recognition and modification by the E. coli pseudouridine synthase RluE
J. Mol. Biol.
430
1284-1294
2018
Escherichia coli (P75966), Escherichia coli K12 (P75966)
Fitzek, E.; Joardar, A.; Gupta, R.; Geisler, M.
Evolution of eukaryal and archaeal pseudouridine synthase Pus10
J. Mol. Evol.
86
77-89
2018
Arabidopsis thaliana (F4HSS8), Homo sapiens (Q3MIT2), Methanocaldococcus jannaschii (Q60346), Pyrococcus furiosus (Q8U1R6)
Lovejoy, A.F.; Riordan, D.P.; Brown, P.O.
Transcriptome-wide mapping of pseudouridines pseudouridine synthases modify specific mRNAs in S. cerevisiae
PLoS ONE
9
e110799
2014
Saccharomyces cerevisiae (P48567), Saccharomyces cerevisiae (P53294), Saccharomyces cerevisiae (Q12211), Saccharomyces cerevisiae ATCC 204508 (P48567), Saccharomyces cerevisiae ATCC 204508 (P53294), Saccharomyces cerevisiae ATCC 204508 (Q12211)
Huet, T.; Miannay, F.A.; Patton, J.R.; Thore, S.
Steroid receptor RNA activator (SRA) modification by the human pseudouridine synthase 1 (hPus1p) RNA binding, activity, and atomic model
PLoS ONE
9
e94610
2014
Homo sapiens (Q9Y606), Homo sapiens
Deryusheva, S.; Gall, J.G.
Dual nature of pseudouridylation in U2 snRNA Pus1p-dependent and Pus1p-independent activities in yeasts and higher eukaryotes
RNA
23
1060-1067
2017
Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster, Mus musculus, Schizosaccharomyces pombe, Xenopus tropicalis, Saccharomyces cerevisiae BY4741, Drosophila melanogaster yw, Schizosaccharomyces pombe 972
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