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Disease on EC 5.4.99.9 - UDP-galactopyranose mutase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
acetyl-coa c-acyltransferase deficiency
Inhibition of the glycine cleavage system by branched-chain amino acid metabolites.
Acidosis
Concentration of 2,3 bisphosphoglycerate in cattle affected with acute ruminal acidosis.
Aspergillosis
Crystal structures and small-angle X-ray scattering analysis of UDP-galactopyranose mutase from the pathogenic fungus Aspergillus fumigatus.
Brain Ischemia
Structural Basis of the Molecular Switch between Phosphatase and Mutase Functions of Human Phosphomannomutase 1 under Ischemic Conditions.
Breast Neoplasms
UGM: a more stable procedure for large-scale multiple testing problems, new solutions to identify oncogene.
Carcinogenesis
A practical method to screen and identify functioning biomarkers in nasopharyngeal carcinoma.
Evidence that androgen-independent stromal growth factor signals promote androgen-insensitive prostate cancer cell growth in vivo.
Role of mesenchymal-epithelial interactions in normal and abnormal development of the mammary gland and prostate.
Role of the stromal microenvironment in carcinogenesis of the prostate.
Carcinoma
A human prostatic epithelial model of hormonal carcinogenesis.
Influence of male genital tract mesenchymes on differentiation of Dunning prostatic adenocarcinoma.
Role of mesenchymal-epithelial interactions in normal and abnormal development of the mammary gland and prostate.
Chagas Disease
Chemical mechanism of UDP-galactopyranose mutase from Trypanosoma cruzi: a potential drug target against Chagas' disease.
Colorectal Neoplasms
Purification and identification of monoubiquitin-phosphoglycerate mutase B complex from human colorectal cancer tissues.
Communicable Diseases
The impact of suitability of empirical antibiotics use on therapeutic outcome of respiratory tract infection patients at inpatient wards of Universitas Gadjah Mada Academic Hospital.
Genetic Diseases, Inborn
Recognition, isolation, and characterization of rat liver D-methylmalonyl coenzyme A hydrolase.
Heart Failure
Atrial natriuretic factor as a marker in congestive heart failure.
Infections
Characterization of the Caenorhabditis elegans UDP-galactopyranose mutase homolog glf-1 reveals an essential role for galactofuranose metabolism in nematode surface coat synthesis.
Molecular Dynamics Simulations of Substrate Release from Trypanosoma cruzi UDP-Galactopyranose Mutase.
Porphyromonas gingivalis Placental Atopobiosis and Inflammatory Responses in Women With Adverse Pregnancy Outcomes.
Specificity of a UDP-GalNAc pyranose-furanose mutase: a potential therapeutic target for Campylobacter jejuni infections.
The impact of suitability of empirical antibiotics use on therapeutic outcome of respiratory tract infection patients at inpatient wards of Universitas Gadjah Mada Academic Hospital.
[Prevalence of urogenital mycoplasma infection in women infected with HIV in Bangui (Central African Republic)]
Infertility
Antifertility and ultrastructural effects of optical isomers of gossypol administered intratesticularly in rats.
[Urogenital mycoplasmosis and Mycoplasma carriage during pregnancy and in inflammatory processes of the genitalia in workers in the electronics industry]
Ischemic Stroke
SLC17A3 rs9379800 and Ischemic Stroke Susceptibility at the Northern Region of Malaysia.
Leishmaniasis
Identification of novel inhibitors against UDP-galactopyranose mutase to combat leishmaniasis.
Leishmaniasis, Visceral
Alkaloids and leishmania donovani UDP-galactopyarnose mutase: Anovel approach in drug designing against Visceral leishmaniasis.
Lung Neoplasms
A practical method to screen and identify functioning biomarkers in nasopharyngeal carcinoma.
Melanoma
Cobalamin metabolism in methionine-dependent human tumour and leukemia cell lines.
Mitochondrial Myopathies
Neuromuscular disorders in infancy and childhood.
Muscle Hypotonia
Neuromuscular disorders in infancy and childhood.
Muscular Atrophy, Spinal
Neuromuscular disorders in infancy and childhood.
Muscular Dystrophies
Neuromuscular disorders in infancy and childhood.
Neoplasms
A human prostatic epithelial model of hormonal carcinogenesis.
Evidence that androgen-independent stromal growth factor signals promote androgen-insensitive prostate cancer cell growth in vivo.
Morphologic and biochemical alterations in rat prostatic tumors induced by fetal urogenital sinus mesenchyme.
Normal and abnormal development of the male urogenital tract. Role of androgens, mesenchymal-epithelial interactions, and growth factors.
Phosphoglycerate mutase, 2,3-bisphosphoglycerate phosphatase and enolase activity and isoenzymes in lung, colon and liver carcinomas.
Osteoarthritis
The association between degenerative hip joint pathology and size of the gluteus maximus and tensor fascia lata muscles.
phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) deficiency
Phosphorus magnetic resonance spectroscopy of partially blocked muscle glycolysis. An in vivo study of phosphoglycerate mutase deficiency.
Polycythemia
Erythrocytosis due to bisphosphoglycerate mutase deficiency with concurrent glucose-6-phosphate dehydrogenase (G-6-PD) deficiency.
Hereditary erythrocytosis, thrombocytosis and neutrophilia.
Polycythemia and oxygen sensing.
Propionic Acidemia
Biochemical and anaplerotic applications of in vitro models of propionic acidemia and methylmalonic acidemia using patient-derived primary hepatocytes.
Gestational age-related reference values for amniotic fluid organic acids.
Identification of 2,2-Dimethylbutanoic Acid (HST5040), a Clinical Development Candidate for the Treatment of Propionic Acidemia and Methylmalonic Acidemia.
Inhibition of the glycine cleavage system by branched-chain amino acid metabolites.
propionyl-coa carboxylase deficiency
Inhibition of the glycine cleavage system by branched-chain amino acid metabolites.
Protein Deficiency
A diagnostic algorithm for metabolic myopathies.
Respiratory Tract Infections
The impact of suitability of empirical antibiotics use on therapeutic outcome of respiratory tract infection patients at inpatient wards of Universitas Gadjah Mada Academic Hospital.
Sexually Transmitted Diseases
[Prevalence of urogenital mycoplasma infection in women infected with HIV in Bangui (Central African Republic)]
Small Cell Lung Carcinoma
A practical method to screen and identify functioning biomarkers in nasopharyngeal carcinoma.
Tuberculosis
A Microbiological, Toxicological, and Biochemical Study of the Effects of Fucoxanthin, a Marine Carotenoid, on Mycobacterium tuberculosis and the Enzymes Implicated in Its Cell Wall: A Link Between Mycobacterial Infection and Autoimmune Diseases.
A Second, Druggable Binding Site in UDP-Galactopyranose Mutase from Mycobacterium tuberculosis?
Antimycobacterial activity of UDP-galactopyranose mutase inhibitors.
Biosynthesis of Galactan in Mycobacterium tuberculosis as a Viable TB Drug Target?
Biosynthesis of the galactan component of the mycobacterial cell wall.
Chemical probes of UDP-galactopyranose mutase.
Combined molecular dynamics, STD-NMR, and CORCEMA protocol yields structural model for a UDP-galactopyranose mutase-inhibitor complex.
Comparing Galactan Biosynthesis in Mycobacterium tuberculosis and Corynebacterium diphtheriae.
Conformational Control of UDP-Galactopyranose Mutase Inhibition.
Contributions of unique active site residues of eukaryotic UDP-galactopyranose mutases to substrate recognition and active site dynamics.
Crystal structures of Mycobacteria tuberculosis and Klebsiella pneumoniae UDP-galactopyranose mutase in the oxidised state and Klebsiella pneumoniae UDP-galactopyranose mutase in the (active) reduced state.
Drug targeting Mycobacterium tuberculosis cell wall synthesis: development of a microtiter plate-based screen for UDP-galactopyranose mutase and identification of an inhibitor from a uridine-based library.
Expression, purification and preliminary X-ray crystallographic analysis of UDP-galactopyranose mutase from Deinococcus radiodurans.
Identification of eukaryotic UDP-galactopyranose mutase inhibitors using the ThermoFAD assay.
Identification of inhibitors of UDP-galactopyranose mutase via combinatorial in situ screening.
Identification of potential inhibitors for mycobacterial uridine diphosphogalactofuranose-galactopyranose mutase enzyme: A novel drug target through in silico approach.
Inhibitors of UDP-galactopyranose mutase thwart mycobacterial growth.
Ligand binding and substrate discrimination by UDP-galactopyranose mutase.
Natural and Synthetic Flavonoids as Potent Mycobacterium tuberculosis UGM Inhibitors.
Potent ligands for prokaryotic UDP-galactopyranose mutase that exploit an enzyme subsite.
Reversible and efficient inhibition of UDP-galactopyranose mutase by electrophilic, constrained and unsaturated UDP-galactitol analogues.
Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase from Mycobacterium tuberculosis Using Substrate and Tetrafluorinated Substrate Analogues.
Synthesis and biological evaluation of nonionic substrate mimics of UDP-Galp as candidate inhibitors of UDP galactopyranose mutase (UGM).
Synthesis and evaluation of heterocycle structures as potential inhibitors of Mycobacterium tuberculosis UGM.
Synthesis and evaluation of nitrofuranylamides as novel antituberculosis agents.
Synthesis of a carbasugar analogue of a putative intermediate in the UDP-galp-mutase catalyzed isomerization.
Tetrafluorination of sugars as strategy for enhancing protein-carbohydrate affinity: application to UDP-Galp mutase inhibition.
udp-galactopyranose mutase deficiency
Anaesthetic considerations in a child with methylmalonic acidemia and its literature review.
Anaesthetic considerations in a patient with methylmalonyl-coenzyme A mutase deficiency.
Anesthetic management of a child with methylmalonyl-coenzyme A mutase deficiency.
Causes of and diagnostic approach to methylmalonic acidurias.
Enzymologic studies on patients with methylmalonic aciduria: basis for a clinical trial of deoxyadenosylcobalamin in a hydroxocobalamin-unresponsive patient.
Epilepsy in children with methylmalonic acidemia: Electroclinical features and prognosis.
Gestational age-related reference values for amniotic fluid organic acids.
Inhibition of the glycine cleavage system by branched-chain amino acid metabolites.
Methylmalonic acidemia with a severe chemical but benign clinical phenotype.
Methylmalonic semialdehyde dehydrogenase deficiency: psychomotor delay and methylmalonic aciduria without metabolic decompensation.
Neuromuscular disorders in infancy and childhood.
Phosphorus magnetic resonance spectroscopy of partially blocked muscle glycolysis. An in vivo study of phosphoglycerate mutase deficiency.
Polycythemia and oxygen sensing.
Prenatal diagnosis for methylmalonic acidemia and inborn errors of vitamin B12 metabolism and transport.
Prolonged exclusive breast-feeding from vegan mother causing an acute onset of isolated methylmalonic aciduria due to a mild mutase deficiency.
Screening for methylmalonic aciduria in Alberta: a voluntary program with particular significance for the Hutterite Brethren.
Selective Screening for Organic Acidurias and Amino Acidopathies in Pakistani Children.
Stabilization of blood methylmalonic acid level in methylmalonic acidemia after liver transplantation.
Varying neurological phenotypes among muto and mut- patients with methylmalonylCoA mutase deficiency.