ferns are known to produce onoceroids including onoceranes and serratanes having unusual structures among triterpenes. Serratanes are directly biosynthesized from pre-alpha-onocerin, synthesized by pre-alpha-onocerin synthase, and not from alpha-onocerin, synthesized by alpha-onocerin synthase, EC 5.4.99.66, from pre-alpha-onocerin
ferns are known to produce onoceroids including onoceranes and serratanes having unusual structures among triterpenes. Serratanes are directly biosynthesized from pre-alpha-onocerin, synthesized by pre-alpha-onocerin synthase, and not from alpha-onocerin, synthesized by alpha-onocerin synthase, EC 5.4.99.66, from pre-alpha-onocerin
while the heterologous LCC gene expression produces the bicyclic triterpene pre-alpha-onocerin, a combination of LCC and alpha-onocerin synthase LCD produces onoceranes, and that of LCC and tohogenol synthase LCE produces serratanes
functional recombinant enzyme expression in Saccharomyces cerevisiae strain GIL77, coexpression with alpha-onocerin synthase leading to the production of tohogenol and serratenediol, NMR metabolite identification, overview
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5.4.99.65 pre-alpha-onocerin synthase
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