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Information on EC 5.4.99.61 - precorrin-8X methylmutase

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EC Tree
     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.61 precorrin-8X methylmutase
IUBMB Comments
The enzyme catalyses the the conversion of precorrin-8X to hydrogenobyrinate by methyl rearrangement, a step in the aerobic (late cobalt insertion) pathway of adenosylcobalamin biosynthesis. The equivalent enzyme in the anaerobic pathway is EC 5.4.99.60, precorrin-8 methylmutase.
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The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
CoBH, GenBank AE000809-derived protein GI 2621284, GenBank U67537-derived protein GI 1499765, Gene cbiC precorrin-8x isomerase, Gene cobH precorrin-8x isomerase, Hydrogenobyrinic acid-binding protein, Isomerase, precorrin (Methanobacterium thermoautothrophicum strain DELTAH gene MTH227), Isomerase, precorrin (Methanococcus jannaschii gene MJ0930), Mutase, precorrin 8x, Precorrin isomerase, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
Precorrin-8X = hydrogenobyrinate
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