Information on EC 5.4.99.57 - baruol synthase

BARS1

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PEN2

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(3S)-2,3-epoxy-2,3-dihydrosqualene = baruol

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KEGG

Sesquiterpenoid and triterpenoid biosynthesis

MetaCyc

baruol biosynthesis

(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, baruol-forming)

The enzyme from Arabidopsis thaliana also produces traces of 22 other triterpenoids.

(3S)-2,3-epoxy-2,3-dihydrosqualene

baruol

Arabidopsis thaliana

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717702

Substrates: -
Products: major product baruol (90%) and 22 minor products (0.02-3% each) which are columbiol, sasanqual, dammara-20,24-dienol, podioda-7,17,21-trienol, delta-amyrin, malabarica-14(27),17,21-trienol, isomultiflorenol, achilleol A, lemmaphylladienol, taraxerol, isoturicallol, camelliol C, taraxasterol, psi-taraxasterol, lupeol, beta-amyrin, multifluorenol, alpha-amyrin, butyrospermol, tirucalla-7,24-dienol and an unidentified DELTA5 triterpene

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Highest Expressing Human Cell Lines

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ExplorEnz (official portal for IUBMB Enzyme Nomenclature)

Expasy Enzyme Nomenclature Database

KEGG

SABIO-RK

NCBI: PubMed, Protein, Nucleotide, Structure, Gene, OMIM

Enzyme Nomenclature (alternative site)

UniProt

PDB

PROSITE Database of protein families and domains

InterPro (database of protein families, domains and functional sites)