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IUBMB Comments The enzyme from Kalanchoe daigremontiana also gives traces of other triterpenoids.
The expected taxonomic range for this enzyme is: Kalanchoe daigremontiana
Synonyms GLS, more
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(3S)-2,3-epoxy-2,3-dihydrosqualene = glutinol
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MetaCyc
pentacyclic triterpene biosynthesis
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(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, glutinol-forming)
The enzyme from Kalanchoe daigremontiana also gives traces of other triterpenoids.
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(3S)-2,3-epoxy-2,3-dihydrosqualene
glutinol
Substrates: - Products: main product is glutinol with 66% yield, minor products are friedelin (14%), beta-amyrin (11%), and taraxerol (8%)
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UniProt
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the enzyme is expressed only in the epidermis layers lining the upper and lower surfaces of the leaf blade
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Highest Expressing Human Cell Lines
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GLUTS_KALDA
767
0
88148
Swiss-Prot
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expressed in Saccharomyces cerevisiae
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Wang, Z.; Yeats, T.; Han, H.; Jetter, R.
Cloning and characterization of oxidosqualene cyclases from Kalanchoe daigremontiana: enzymes catalyzing up to 10 rearrangement steps yielding friedelin and other triterpenoids
J. Biol. Chem.
285
29703-29712
2010
Kalanchoe daigremontiana (E2IUA7)
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