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Information on EC 5.4.99.36 - isomultiflorenol synthase and Organism(s) Luffa aegyptiaca and UniProt Accession Q948R6

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EC Tree
     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.36 isomultiflorenol synthase
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This record set is specific for:
Luffa aegyptiaca
UNIPROT: Q948R6 not found.
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The taxonomic range for the selected organisms is: Luffa aegyptiaca
The expected taxonomic range for this enzyme is: Luffa aegyptiaca
Synonyms
isomultiflorenol synthase, lcims1, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
isomultiflorenol synthase
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LcIMS1
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-
-
-
PATHWAY SOURCE
PATHWAYS
-
-
SYSTEMATIC NAME
IUBMB Comments
(S)-2,3-epoxysqualene mutase (cyclizing, isomultiflorenol-forming)
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(S)-squalene-2,3-epoxide
isomultiflorenol
show the reaction diagram
-
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
isomultiflorenol synthase is an oxidosqualene cyclase involved in bryonolic acid biosynthesis in cultured Luffa cells
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
IMFS_LUFAE
759
0
87840
Swiss-Prot
other Location (Reliability: 2)
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in ERG7-deficient Saccharomyces cerevisiae mutant GIL77
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
isomultiflorenol synthase mRNA is low during the early stages of cell growth and accumulats to relatively high levels in the late stages
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hayashi, H.; Huang, P.; Inoue, K.; Hiraoka, N.; Ikeshiro, Y.; Yazaki, K.; Tanaka, S.; Kushiro, T.; Shibuya, M.; Ebizuka, Y.
Molecular cloning and characterization of isomultiflorenol synthase, a new triterpene synthase from Luffa cylindrica, involved in biosynthesis of bryonolic acid
Eur. J. Biochem.
268
6311-6317
2001
Luffa aegyptiaca (Q948R6), Luffa aegyptiaca
Manually annotated by BRENDA team