Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Information on EC 5.4.2.10 - phosphoglucosamine mutase

for references in articles please use BRENDA:EC5.4.2.10

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

The enzyme is involved in the pathway for bacterial cell-wall peptidoglycan and lipopolysaccharide biosyntheses, being an essential step in the pathway for UDP-N-acetylglucosamine biosynthesis. The enzyme from Escherichia coli is activated by phosphorylation and can be autophosphorylated in vitro by α-D-glucosamine 1,6-bisphosphate, which is an intermediate in the reaction, α-D-glucose 1,6-bisphosphate or ATP. It can also catalyse the interconversion of α-D-glucose 1-phosphate and glucose 6-phosphate, although at a much lower rate.

The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota

Synonyms
phosphoglucosamine mutase, aq1627, mmp1077, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate
show the reaction diagram
The enzyme is involved in the pathway for bacterial cell-wall peptidoglycan and lipopolysaccharide biosynthesis, being an essential step in the pathway for UDP-N-acetylglucosamine biosynthesis. The enzyme from E. coli is activated by phosphorylation and can be autophosphorylated in vitro by glucosamine 1,6-bisphosphate, which is an intermediate in the reaction, glucose 1,6-bisphosphate or ATP. It can also catalyse the interconversion of glucose 1-phosphate and glucose 6-phosphate, although at a much lower rate
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-, -, -
Highest Expressing Human Cell Lines
Cell Line Links Gene Links