Information on EC 5.3.99.9 - neoxanthin synthase

for references in articles please use BRENDA:EC5.3.99.9
Word Map on EC 5.3.99.9
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Select one or more organisms in this record:

The enzyme appears in viruses and cellular organisms

top print hide
EC NUMBER
COMMENTARY hide
5.3.99.9
-
top print hide
RECOMMENDED NAME
GeneOntology No.
neoxanthin synthase
top print hide
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
violaxanthin = neoxanthin
show the reaction diagram
-
-
-
-
top print hide
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
abscisic acid biosynthesis
-
-
neoxanthin biosynthesis
-
-
Carotenoid biosynthesis
-
-
Metabolic pathways
-
-
Biosynthesis of secondary metabolites
-
-
top print hide
SYSTEMATIC NAME
IUBMB Comments
violaxanthin---neoxanthin isomerase (epoxide-opening)
The opening of the epoxide ring of violaxanthin generates a chiral allene. Neoxanthin is a precursor of the plant hormone abscisic acid and the last product of carotenoid synthesis in green plants [2].
top
top print hide
CAS REGISTRY NUMBER
COMMENTARY hide
318960-21-3
-
top print hide
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
Uniprot
Manually annotated by BRENDA team
plants growing naturally in a forest in Oulu, Finland
-
-
Manually annotated by BRENDA team
top print hide
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
-
the gene encoding the enzyme is involved in catabolism of lycopene into different carotenoids
top print hide
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
violaxanthin
neoxanthin
show the reaction diagram
top print hide
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
violaxanthin
neoxanthin
show the reaction diagram
top print hide
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
additional information
-
gene NXS expression analysis in different genotypes, overview
Manually annotated by BRENDA team
top print hide
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli or transfection of Nicotiana benthamiana leaves
Q9LWA6
gene NXS, expression analysis in different genotypes, overview
-
gene VmNSY, DNA and amino acid sequence determination and analysis, sequence comparisons
-
plant protoplasts obtained from Arabidopsis thaliana tissue culture and Nicotiana tabacum leaves are transformed with the full length cDNA under control of the 35S CaMV promoter by electroporation and PEG
top print hide
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
gene NXS is downregulated at red stage of fruit ripening in red stage genotype EC-521086
-
top
top
top
LINKS TO OTHER DATABASES (specific for EC-Number 5.3.99.9)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
InterPro (database of protein families, domains and functional sites)