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Information on EC 5.3.99.2 - Prostaglandin-D synthase
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5.3.99.2 Prostaglandin-D synthaseIUBMB Comments
Brings about the opening of the epidioxy bridge. Some enzymes require glutathione.
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Word Map
- 5.3.99.2
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cerebrospinal
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arachidonic
- cox-2
- csf
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cyclooxygenase
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prostanoids
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lipocalins
- indomethacin
- creatinine
- cystatin
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mast
- sleep
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glomerular
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seminal
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allergic
- leptomeninges
- aspirin
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eicosanoids
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thromboxane
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leukotriene
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nonsteroidal
- plexus
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nsaid
- medicine
- synthase-1
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subarachnoidal
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1.14.99.1
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ventrolateral
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pgf2alpha
- transthyretin
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preoptic
- rhinorrhea
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endoperoxide
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fistula
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sleep-promoting
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nephelometric
- beta2-microglobulin
- pghs-1
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arachnoid
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hydroperoxidase
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sleep-wake
- analysis
- synthesis
- nutrition
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
l-pgds, prostaglandin synthase, beta-trace protein, ptgds, h-pgds, pgd synthase, prostaglandin d synthase, hpgds, lipocalin-type prostaglandin d synthase, prostaglandin d2 synthase, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
beta-Trace
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Beta-trace protein
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Glutathione-dependent PGD synthetase
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Glutathione-independent PGD synthetase
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H-PGDS
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Hematopoietic prostaglandin D synthase
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Isomerase, prostaglanin R2 D-
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PGD synthase
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PGD2 synthase
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PGDS
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PGDS2
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PGH-PGD isomerase
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Prostaglandin D synthase
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Prostaglandin D2 synthase
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Prostaglandin-D synthase
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Prostaglandin-H2 D-isomerase
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Prostaglandin-R-prostaglandin D isomerase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
isomerization
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intramolecular oxidoreduction
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PATHWAY SOURCE
PATHWAYS
BRENDA
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SYSTEMATIC NAME
IUBMB Comments
(5Z,13E,15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase
Brings about the opening of the epidioxy bridge. Some enzymes require glutathione.
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CAS REGISTRY NUMBER
COMMENTARY
52227-78-8
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate
(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acute Coronary Syndrome
Beta-trace protein and cystatin c as predictors of major bleeding in non-ST-segment elevation acute coronary syndrome.
Acute Coronary Syndrome
The Effect of Beta-Trace Protein on Diagnosis and Prognosis in Patients with Acute Coronary Syndrome.
Acute Coronary Syndrome
Variability in response to aspirin: do we understand the clinical relevance?
Acute Kidney Injury
Beta-Trace Protein as a Potential Marker of Acute Kidney Injury: A Pilot Study.
Acute Kidney Injury
Does Beta-Trace Protein (BTP) Outperform Cystatin C as a Diagnostic Marker of Acute Kidney Injury Complicating the Early Phase of Acute Pancreatitis?
Acute Kidney Injury
Highly elevated levels of prostaglandin D synthase in the serum of patients with renal failure.
Acute Kidney Injury
Temporal alterations in regional gene expression after nephrotoxic renal injury.
Adenocarcinoma
Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice.
Adenoma
Hematopoietic prostaglandin D synthase suppresses intestinal adenomas in ApcMin/+ mice.
Adenoma
High dietary niacin may increase prostaglandin formation but does not increase tumor formation in apc (min/+) mice.
Adenoma
Intestinal tumor suppression in Apc(Min/+) mice by prostaglandin D2 receptor PTGDR.
Aggressive Periodontitis
Single nucleotide polymorphisms associated with aggressive periodontitis and severe chronic periodontitis in Japanese.
AIDS Dementia Complex
Nitrosative stress with HIV dementia causes decreased L-prostaglandin D synthase activity.
Albuminuria
Lipocalin-type prostaglandin D synthase in urine in adriamycin-induced nephropathy of mice.
Albuminuria
Urinary excretions of lipocalin-type prostaglandin D synthase predict renal injury in type-2 diabetes: a cross-sectional and prospective multicentre study.
Alopecia
Anti-Inflammatory, Thrombolytic and Hair-Growth Promoting Activity of the n-Hexane Fraction of the Methanol Extract of Leea indica Leaves.
Alopecia
In silico prediction of prostaglandin D2 synthase inhibitors from herbal constituents for the treatment of hair loss.
alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase deficiency
Hypoglycosylation of a brain glycoprotein (beta-trace protein) in CDG syndromes due to phosphomannomutase deficiency and N-acetylglucosaminyl-transferase II deficiency.
Alzheimer Disease
Abundant neuroprotective chaperone Lipocalin-type prostaglandin D synthase (L-PGDS) disassembles the Amyloid-? fibrils.
Alzheimer Disease
Amyloid ? chaperone - lipocalin-type prostaglandin D synthase acts as a peroxidase in the presence of heme.
Alzheimer Disease
Anticholinergic Drugs Interact With Neuroprotective Chaperone L-PGDS and Modulate Cytotoxicity of A? Amyloids.
Alzheimer Disease
Association of lipocalin-type prostaglandin D synthase with disproportionately enlarged subarachnoid-space in idiopathic normal pressure hydrocephalus.
Alzheimer Disease
Budesonide epimer R, LAU-8080 and phenyl butyl nitrone synergistically repress cyclooxygenase-2 induction in [IL-1beta+Abeta42]-stressed human neural cells.
Alzheimer Disease
Hematopoietic prostaglandin D synthase and DP1 receptor are selectively upregulated in microglia and astrocytes within senile plaques from human patients and in a mouse model of Alzheimer disease.
Anaphylaxis
Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.
Anaphylaxis
Therapeutic Potential of Hematopoietic Prostaglandin D2 Synthase in Allergic Inflammation.
Androgen-Insensitivity Syndrome
A case of complete androgen insensitivity syndrome presenting with incarcerated inguinal hernia: an immunohistochemical study.
Anencephaly
Comparison of alphafetoprotein and beta-trace protein in the antenatal diagnosis of anencephaly and spina bifida.
Angina, Stable
Expression of lipocalin-type prostaglandin D synthase (beta-trace) in human heart and its accumulation in the coronary circulation of angina patients.
Asthma
Development of a scintillation proximity binding assay for high-throughput screening of hematopoietic prostaglandin D2 synthase.
Asthma
Eosinophil production of prostaglandin D2 in patients with aspirin-exacerbated respiratory disease.
Asthma
Identification of new inhibitors for human hematopoietic prostaglandin D2 synthase among FDA-approved drugs and other compounds.
Asthma
Molecular markers of type 2 airway inflammation are similar between eosinophilic severe asthma and eosinophilic chronic obstructive pulmonary disease.
Asthma
New polymorphisms of haematopoietic prostaglandin D synthase and human prostanoid DP receptor genes.
Asthma
Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice.
Asthma
Prostaglandin D2 pathway upregulation: Relation to asthma severity, control, and TH2 inflammation.
Asthma
Protein profiles of CCL5, HPGDS, and NPSR1 in plasma reveal association with childhood asthma.
Asthma
Therapeutic Potential of Hematopoietic Prostaglandin D2 Synthase in Allergic Inflammation.
Asthma, Aspirin-Induced
Role of expression of prostaglandin synthases 1 and 2 and leukotriene C(4) synthase in aspirin-intolerant asthma: a theoretical study.
Astrocytoma
Increased production of lipocalin-type prostaglandin D synthase in leptomeningeal cells through contact with astrocytes.
Astrocytoma
Loss of prostaglandin D2 synthase: a key molecular event in the transition of a low-grade astrocytoma to an anaplastic astrocytoma.
Atherosclerosis
A novel pathway to enhance adipocyte differentiation of 3T3-L1 cells by up-regulation of lipocalin-type prostaglandin D synthase mediated by liver X receptor-activated sterol regulatory element-binding protein-1c.
Atherosclerosis
Accelerated glucose intolerance, nephropathy, and atherosclerosis in prostaglandin D2 synthase knock-out mice.
Atherosclerosis
Association of serum lipocalin-type prostaglandin D synthase levels with subclinical atherosclerosis in untreated asymptomatic subjects.
Atherosclerosis
Genome-wide significant locus of beta-trace protein, a novel kidney function biomarker, identified in European and African Americans.
Atherosclerosis
Identification of gene polymorphism in lipocalin-type prostaglandin D synthase and its association with carotid atherosclerosis in Japanese hypertensive patients.
Atherosclerosis
Inhibition of cell cycle progression and migration of vascular smooth muscle cells by prostaglandin D2 synthase: resistance in diabetic Goto-Kakizaki rats.
Atherosclerosis
Knockout of the l-pgds gene aggravates obesity and atherosclerosis in mice.
Atherosclerosis
Lipocalin-type prostaglandin D2 synthase deletion induces dyslipidemia and non-alcoholic fatty liver disease.
Atrial Fibrillation
Elevated Serum Beta-Trace Protein Levels are Associated With the Presence of Atrial Fibrillation in Hypertension Patients.
Azoospermia
Biomarkers for demographic research: sperm counts and other male infertility biomarkers.
Azoospermia
Relationship between lipocalin-type prostaglandin D synthase and alpha-glucosidase in azoospermia seminal plasma.
Azoospermia
Seminal plasma lipocalin-type prostaglandin D synthase: a potential new marker for the diagnosis of obstructive azoospermia.
Bacterial Infections
Induction and function of lipocalin prostaglandin D synthase in host immunity.
Brain Edema
Lipocalin-prostaglandin D synthase is a critical beneficial factor in transient and permanent focal cerebral ischemia.
Brain Edema
Mediators of injury in neurotrauma: intracellular signal transduction and gene expression.
Brain Injuries
Dexamethasone protects neonatal hypoxic-ischemic brain injury via L-PGDS-dependent PGD2-DP1-pERK signaling pathway.
Brain Injuries
Early induction of neuronal lipocalin-type prostaglandin D synthase after hypoxic-ischemic injury in developing brains.
Brain Ischemia
1alpha,25-Dihydroxyvitamin D(3) treatment does not alter neuronal cyclooxygenase-2 expression in the cerebral cortex after stroke.
Brain Ischemia
L-PGDS Mediates Vagus Nerve Stimulation-Induced Neuroprotection in a Rat Model of Ischemic Stroke by Suppressing the Apoptotic Response.
Brain Ischemia
Lipocalin-prostaglandin D synthase is a critical beneficial factor in transient and permanent focal cerebral ischemia.
Brain Ischemia
Protective role of hematopoietic prostaglandin D synthase in transient focal cerebral ischemia in mice.
Brain Neoplasms
Genes Encoding Mammalian Oviductal Proteins Involved in Fertilization are Subjected to Gene Death and Positive Selection.
Brain Neoplasms
Identification and comparative proteomic study of quail and duck egg white protein using 2-dimensional gel electrophoresis and matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometry analysis.
Brain Neoplasms
Proteomic profiling of cerebrospinal fluid identifies prostaglandin D2 synthase as a putative biomarker for pediatric medulloblastoma: A pediatric brain tumor consortium study.
Brain Neoplasms
Quantification of prostaglandin D synthetase in cerebrospinal fluid: a potential marker for brain tumor.
Breast Cyst
Immunofluorometric assay of prostaglandin D synthase in human tissue extracts and fluids.
Breast Cyst
Quantification of pepsinogen C and prostaglandin D synthase in breast cyst fluid and their potential utility for cyst type classification.
Breast Neoplasms
Combination chemoprevention of HER2/neu-induced breast cancer using a cyclooxygenase-2 inhibitor and a retinoid X receptor-selective retinoid.
Breast Neoplasms
Common polymorphisms in the prostaglandin pathway genes and their association with breast cancer susceptibility and survival.
Breast Neoplasms
Cyclooxygenase-2 expression: a potential prognostic and predictive marker for high-grade ductal carcinoma in situ of the breast.
Breast Neoplasms
Immunofluorometric assay of prostaglandin D synthase in human tissue extracts and fluids.
Breast Neoplasms
Prostaglandin D2 synthase/prostaglandin D2/TWIST2 signaling inhibits breast cancer proliferation.
Breast Neoplasms
Tumour-Infiltrating Immune Cell-Based Subtyping and Signature Gene Analysis in Breast Cancer Based on Gene Expression Profiles.
Carcinogenesis
A new cyclo-oxygenase-2 gene variant in the Han Chinese population is associated with an increased risk of gastric carcinoma.
Carcinogenesis
Cyclooxygenase-2 expression: a potential prognostic and predictive marker for high-grade ductal carcinoma in situ of the breast.
Carcinogenesis
Prostaglandin D synthase (beta-trace) in human arachnoid and meningioma cells: roles as a cell marker or in cerebrospinal fluid absorption, tumorigenesis, and calcification process.
Carcinogenesis
Prostaglandin synthases influence thyroid follicular cell proliferation but not carcinogenesis in rats initiated with N-bis(2-hydroxypropyl)nitrosamine.
Carcinogenesis
Transcriptional activation of cyclooxygenase-2 in Wnt-1-transformed mouse mammary epithelial cells.
Carcinoma
Decisive role of cyclooxygenase-2 and lipocalin-type prostaglandin D synthase in chemotherapeutics-induced apoptosis of human cervical carcinoma cells.
Carcinoma
Expression and biological role of the prostaglandin D synthase/SOX9 pathway in human ovarian cancer cells.
Carcinoma
Prostaglandin D synthase does not produce prostate-specific antigen cross-reactivity in renal cell carcinoma.
Carcinoma
Prostaglandin d synthase is a potential novel therapeutic agent for the treatment of gastric carcinomas expressing PPAR?
Carcinoma
Simultaneous expression of cyclooxygenase-2 and microsomal prostaglandin E synthase in squamous cell carcinoma of the larynx.
Carcinoma
SNX10 and PTGDS are associated with the progression and prognosis of cervical squamous cell carcinoma.
Carcinoma, Ductal
Biological markers of risk in nipple aspirate fluid are associated with residual cancer and tumour size.
Carcinoma, Ductal
HER2/neu-induced mammary tumorigenesis and angiogenesis are reduced in cyclooxygenase-2 knockout mice.
Carcinoma, Intraductal, Noninfiltrating
Biological markers of risk in nipple aspirate fluid are associated with residual cancer and tumour size.
Carcinoma, Intraductal, Noninfiltrating
HER2/neu-induced mammary tumorigenesis and angiogenesis are reduced in cyclooxygenase-2 knockout mice.
Carcinoma, Non-Small-Cell Lung
Characterization of the prostaglandin biosynthetic pathway in non-small cell lung cancer: a comparison with small cell lung cancer and correlation with angiogenesis, angiogenic factors and metastases.
Carcinoma, Renal Cell
Prostaglandin D synthase does not produce prostate-specific antigen cross-reactivity in renal cell carcinoma.
Carcinoma, Squamous Cell
SNX10 and PTGDS are associated with the progression and prognosis of cervical squamous cell carcinoma.
Cardiovascular Diseases
A urine biomarker for severe OSA patients: lipocaline-type prostaglandin D synthase.
Cardiovascular Diseases
Biochemistry of protein tyrosine nitration in cardiovascular pathology.
Cardiovascular Diseases
HIF-1?-l-PGDS-PPAR? regulates hypoxia-induced ANP secretion in beating rat atria.
Carotid Artery Diseases
Identification of gene polymorphism in lipocalin-type prostaglandin D synthase and its association with carotid atherosclerosis in Japanese hypertensive patients.
Cataplexy
Narcolepsy increased L-PGDS (beta-trace) levels correlate with excessive daytime sleepiness but not with cataplexy.
Central Nervous System Diseases
Capillary electrophoretic analyses of beta-trace protein and other low molecular weight proteins in cerebrospinal fluid from patients with central nervous system diseases.
Central Nervous System Diseases
Proteoform analysis of lipocalin-type prostaglandin D-synthase from human cerebrospinal fluid by isoelectric focusing and superficially porous liquid chromatography with fourier transform mass spectrometry.
Central Nervous System Diseases
Sodium dodecyl sulfate-capillary gel electrophoretic analysis of molecular mass microheterogeneity of beta-trace protein in cerebrospinal fluid from patients with central nervous system diseases.
Cerebral Infarction
Capillary-zone electrophoretic analyses of the proteins and amino acid components in cerebrospinal fluid of central nervous system diseases.
Cerebrospinal Fluid Leak
?-Trace Protein: From GFR Marker to Cardiovascular Risk Predictor.
Cerebrospinal Fluid Leak
Beta-trace Protein as a new non-invasive immunological Marker for Quinolinic Acid-induced impaired Blood-Brain Barrier Integrity.
Cerebrospinal Fluid Leak
Beta-trace protein: an unknown marker for cerebrospinal fluid leaks.
Cerebrospinal Fluid Leak
Cerebrospinal fluid leakage: agarose gel electrophoresis detection of beta(2)-transferrin and nephelometric quantification of beta-trace protein.
Cerebrospinal Fluid Leak
Predictability of quantification of beta-trace protein for diagnosis of cerebrospinal fluid leak: cutoff determination in nasal fluids with two control groups.
Cerebrospinal Fluid Leak
Rapid, accurate and non-invasive detection of cerebrospinal fluid leakage using combined determination of beta-trace protein in secretion and serum.
Cerebrospinal Fluid Leak
Sample-dependent diagnostic accuracy of prostaglandin D synthase in cerebrospinal fluid leak.
Cerebrospinal Fluid Leak
[Analysis of beta-"trace" protein detects leakage of cerebrospinal fluid. Quickly, safely and cheaply]
Cerebrospinal Fluid Rhinorrhea
beta-Trace protein as a marker for cerebrospinal fluid rhinorrhea.
Cerebrospinal Fluid Rhinorrhea
Beta-trace protein test: new guidelines for the reliable diagnosis of cerebrospinal fluid fistula.
Cerebrospinal Fluid Rhinorrhea
[CSF rhinorrhea is an important differential diagnosis for patients with long-lasting runny nose].
Cholecystitis, Acute
Effect of indomethacin on gallbladder inflammation and contractility during acute cholecystitis.
Cholestasis
Delay in hepatocyte proliferation and prostaglandin D2 synthase expression for cholestasis due to endotoxin during partial hepatectomy in rats.
Colitis
Increased expression of lipocalin-type-prostaglandin D synthase in ulcerative colitis and exacerbating role in murine colitis.
Colitis
Mast cell-derived prostaglandin D2 inhibits colitis and colitis-associated colon cancer in mice.
Colitis
Resolution of Cox mediated inflammation by Se supplementation in mouse experimental model of colitis.
Colonic Neoplasms
Both stromal cell and colonocyte epidermal growth factor receptors control HCT116 colon cancer cell growth in tumor xenografts.
Colorectal Neoplasms
Hematopoietic prostaglandin D synthase (HPGDS): A high stability, Val187Ile isoenzyme common among African Americans and its relationship to risk for colorectal cancer.
Colorectal Neoplasms
Polymorphisms in prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) and risk of colorectal cancer.
Colorectal Neoplasms
Prognostic markers in early-stage colorectal cancer: significance of TYMS mRNA expression.
Colorectal Neoplasms
Prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) 8473T>C polymorphism associated with prognosis for patients with colorectal cancer treated with capecitabine and oxaliplatin.
Colorectal Neoplasms
The prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/ COX2) rs5277 polymorphism does not influence risk of colorectal cancer in an Iranian population.
Compartment Syndromes
Cerebrospinal fluid dynamics between the intracranial and the subarachnoid space of the optic nerve. Is it always bidirectional?
Compartment Syndromes
Optic nerve compartment syndrome in a patient with optic nerve sheath meningioma.
Congenital Disorders of Glycosylation
beta-Trace protein in human cerebrospinal fluid: a diagnostic marker for N-glycosylation defects in brain.
Congenital Disorders of Glycosylation
Hypoglycosylation of a brain glycoprotein (beta-trace protein) in CDG syndromes due to phosphomannomutase deficiency and N-acetylglucosaminyl-transferase II deficiency.
Coronary Artery Disease
High-sensitivity Troponin I Predicts Galectin-3 in Chronic Kidney Disease Patients.
Coronary Artery Disease
Lipocalin-type prostaglandin D synthase is a powerful biomarker for severity of stable coronary artery disease.
Coronary Artery Disease
Lipocalin-type prostaglandin D synthase is not a biomarker of atherosclerotic manifestations.
Coronary Artery Disease
[Functional analyses of lipocalin-type and hematopoietic prostaglandin D synthases]
Coronary Vasospasm
Lipocalin-Type PGD Synthase as a Novel Biomarker for Coronary Vasospasm.
Coronary Vasospasm
Lipocalin-type prostaglandin d synthase is associated with coronary vasospasm and vasomotor reactivity in response to acetylcholine.
COVID-19
Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 infection.
Cysts
High beta-trace protein concentration in the fluid of an orbital cyst associated with bilateral colobomatous microphthalmos.
Cysts
Quantification of pepsinogen C and prostaglandin D synthase in breast cyst fluid and their potential utility for cyst type classification.
Dehydration
Cyclooxygenase-2, prostaglandin synthases, and prostaglandin H2 metabolism in traumatic brain injury in the rat.
Dehydration
Stable expression of lipocalin-type prostaglandin D synthase in cultured preadipocytes impairs adipogenesis program independently of endogenous prostanoids.
Dementia
Contribution of prostaglandin D2 synthase to progression of renal failure and dialysis dementia.
Dementia
Prostaglandin D2 synthase: Apoptotic factor in alzheimer plasma, inducer of reactive oxygen species, inflammatory cytokines and dialysis dementia.
Dementia
Quantification of prostaglandin D synthetase in cerebrospinal fluid: a potential marker for brain tumor.
Demyelinating Diseases
Prostaglandin D2-mediated microglia/astrocyte interaction enhances astrogliosis and demyelination in twitcher.
Dermatitis
Opposing immunomodulatory roles of prostaglandin D2 during the progression of skin inflammation.
Dermatitis
Time course changes of scratching counts, dermatitis symptoms, and levels of cutaneous prostaglandins in NC/Nga mice.
Dermatitis, Atopic
Increased expression of hematopoietic prostaglandin D synthase in CCR4-positive T cells from patients with atopic dermatitis.
Dermatitis, Atopic
Therapeutic Potential of Hematopoietic Prostaglandin D2 Synthase in Allergic Inflammation.
Diabetes Mellitus
Post-translational modification regulates prostaglandin D2 synthase apoptotic activity: characterization by site-directed mutagenesis.
Diabetes Mellitus
Urinary beta-trace protein gene expression analysis in type 2 diabetes mellitus patients.
Diabetes Mellitus
Urinary prostaglandin D synthase (beta-trace) excretion increases in the early stage of diabetes mellitus.
Diabetes Mellitus, Type 1
Aberrant monocyte prostaglandin synthase 2 (PGS2) expression in type 1 diabetes before and after disease onset.
Diabetes Mellitus, Type 1
Aberrant prostaglandin synthase 2 expression defines an antigen-presenting cell defect for insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
IL10 resistant PGS2 expression in at-risk/Type 1 diabetic human monocytes.
Diabetes Mellitus, Type 2
A novel pathway to enhance adipocyte differentiation of 3T3-L1 cells by up-regulation of lipocalin-type prostaglandin D synthase mediated by liver X receptor-activated sterol regulatory element-binding protein-1c.
Diabetes Mellitus, Type 2
Accelerated glucose intolerance, nephropathy, and atherosclerosis in prostaglandin D2 synthase knock-out mice.
Diabetes Mellitus, Type 2
Lipocalin-type prostaglandin D(2) synthase stimulates glucose transport via enhanced GLUT4 translocation.
Diabetes Mellitus, Type 2
Post-translational modification regulates prostaglandin D2 synthase apoptotic activity: characterization by site-directed mutagenesis.
Diabetes Mellitus, Type 2
Urinary beta-trace protein gene expression analysis in type 2 diabetes mellitus patients.
Diabetic Nephropathies
Accelerated glucose intolerance, nephropathy, and atherosclerosis in prostaglandin D2 synthase knock-out mice.
Diabetic Nephropathies
Beta-trace protein, a new marker of GFR, may predict the early prognostic stages of patients with type 2 diabetic nephropathy.
Diabetic Nephropathies
Blood sugar control reverses the increase in urinary excretion of prostaglandin D synthase in diabetic patients.
Diabetic Nephropathies
Development and evaluation of a practical ELISA for human urinary lipocalin-type prostaglandin D synthase.
Diabetic Nephropathies
Urinary excretions of lipocalin-type prostaglandin D2 synthase predict the development of proteinuria and renal injury in OLETF rats.
Diabetic Nephropathies
Urinary lipocalin-type prostaglandin D synthase: a potential marker for early gentamicin-induced renal damage?
Diabetic Retinopathy
Differential expression of vitreous proteins in proliferative diabetic retinopathy.
Disorders of Excessive Somnolence
CSF prostaglandin D synthase is reduced in excessive daytime sleepiness.
Disorders of Excessive Somnolence
Lipocalin-type prostaglandin D synthase levels increase in patients with narcolepsy and idiopathic hypersomnia.
Disorders of Excessive Somnolence
Narcolepsy increased L-PGDS (beta-trace) levels correlate with excessive daytime sleepiness but not with cataplexy.
Disorders of Excessive Somnolence
Prostaglandin D synthase (beta trace) levels in sleep apnea patients with and without sleepiness.
Dyslipidemias
Lipocalin-type prostaglandin D2 synthase deletion induces dyslipidemia and non-alcoholic fatty liver disease.
Egg Hypersensitivity
Lipocalin-Type Prostaglandin D Synthase and Egg White Cystatin React with IgE Antibodies from Children with Egg Allergy.
Encephalitis
Unexpected role of lipocalin-type prostaglandin D synthase in brain: Regulation of glial cell migration and morphology.
Endometrial Neoplasms
Decreased PTGDS Expression Predicting Poor Survival of Endometrial Cancer by Integrating Weighted Gene Co-Expression Network Analysis and Immunohistochemical Validation.
Endometritis
Endometrial expression of selected transcripts involved in prostaglandin synthesis in cows with endometritis.
Endometritis
Endometrial mRNA expression of prostaglandin synthase enzymes PTGS 2, PTGFS and mPTGES 1 in repeat-breeding cows with cytologically determined endometritis.
Endometritis
Targeted transcript analysis revealed association of suboptimal expression of certain endometrial immunity-related genes with disparate uterine diseases in zebu cows.
Fatty Liver
Lipocalin-type prostaglandin D2 synthase deletion induces dyslipidemia and non-alcoholic fatty liver disease.
Fibromyalgia
Prostaglandin D synthase concentration in cerebrospinal fluid and serum of patients with neurological disorders.
Folliculitis
Indomethacin inhibits eosinophil migration to prostaglandin D2 : therapeutic potential of CRTH2 desensitization for eosinophilic pustular folliculitis.
Folliculitis
Indomethacin-induced reduction in CRTH2 in eosinophilic pustular folliculitis (Ofuji's disease): a proposed mechanism of action.
Food Hypersensitivity
Therapeutic Potential of Hematopoietic Prostaglandin D2 Synthase in Allergic Inflammation.
Gangliosidosis, GM1
Lipocalin-type prostaglandin D synthase is up-regulated in oligodendrocytes in lysosomal storage diseases and binds gangliosides.
Gastritis
Increased expression and cellular localization of lipocalin-type prostaglandin D synthase in Helicobacter pylori-induced gastritis.
Glaucoma
Lipocalin-like Prostaglandin D Synthase (L-PGDS) Concentration in Aqueous Humour in Patients With Open-angle Glaucoma.
Glaucoma
Lipocalin-type Prostaglandin D Synthase Concentration Gradients in the Cerebrospinal Fluid in Normal-tension Glaucoma Patients with Optic Nerve Sheath Compartmentation.
Glaucoma, Open-Angle
Lipocalin-like Prostaglandin D Synthase (L-PGDS) Concentration in Aqueous Humour in Patients With Open-angle Glaucoma.
Glioma
18F-glutathione conjugate as a PET tracer for imaging tumors that overexpress L-PGDS enzyme.
Glioma
Estradiol regulation of lipocalin-type prostaglandin D synthase promoter activity: evidence for direct and indirect mechanisms.
Glomerulonephritis
Development and evaluation of a practical ELISA for human urinary lipocalin-type prostaglandin D synthase.
Glomerulonephritis, IGA
Development and evaluation of a practical ELISA for human urinary lipocalin-type prostaglandin D synthase.
Glucose Intolerance
Accelerated glucose intolerance, nephropathy, and atherosclerosis in prostaglandin D2 synthase knock-out mice.
Glucose Intolerance
Lipocalin-type prostaglandin D(2) synthase stimulates glucose transport via enhanced GLUT4 translocation.
Glucose Intolerance
Lipocalin-type prostaglandin D2 synthase deletion induces dyslipidemia and non-alcoholic fatty liver disease.
Guillain-Barre Syndrome
Beta-trace protein in cerebrospinal fluid: a blood-CSF barrier-related evaluation in neurological diseases.
Guillain-Barre Syndrome
Decreased intrathecal synthesis of prostaglandin D2 synthase in the cerebrospinal fluid of patients with acute inflammatory demyelinating polyneuropathy.
Headache Disorders
Exploration of candidate serum biomarkers potentially related to the chronic pain condition in Medication-overuse headache.
Hearing Loss, Sudden
Traces of perilymph detected in epipharyngeal fluid: perilymphatic fistula as a cause of sudden hearing loss diagnosed with beta-trace protein (prostaglandin D synthase) immunoelectrophoresis.
Hearing Loss, Unilateral
Traces of perilymph detected in epipharyngeal fluid: perilymphatic fistula as a cause of sudden hearing loss diagnosed with beta-trace protein (prostaglandin D synthase) immunoelectrophoresis.
Hematoma, Subdural, Chronic
Correlation of the Beta-trace protein and inflammatory cytokines with magnetic resonance imaging in chronic subdural hematomas : a prospective study.
Herpes Zoster
Oviductal fluid proteins associated with the bovine zona pellucida and the effect on in vitro sperm-egg binding, fertilization and embryo development.
Hydrocephalus
Association of lipocalin-type prostaglandin D synthase with disproportionately enlarged subarachnoid-space in idiopathic normal pressure hydrocephalus.
Hydrocephalus
Lipocalin-type prostaglandin D synthase (beta-trace) in cerebrospinal fluid: a useful marker for the diagnosis of normal pressure hydrocephalus.
Hydrocephalus
Quantification of prostaglandin D synthetase in cerebrospinal fluid: a potential marker for brain tumor.
Hydrocephalus, Normal Pressure
Association of lipocalin-type prostaglandin D synthase with disproportionately enlarged subarachnoid-space in idiopathic normal pressure hydrocephalus.
Hydrocephalus, Normal Pressure
Lipocalin-type prostaglandin D synthase (beta-trace) in cerebrospinal fluid: a useful marker for the diagnosis of normal pressure hydrocephalus.
Hyperalgesia
Dexamethasone Suppresses Radicular Pain Through Targeting the L-PGDS/PI3K/Akt Pathway in Rats With Lumbar Disc Herniation.
Hyperalgesia
Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice.
Hyperalgesia
Prostaglandin D2 contributes to cisplatin-induced neuropathic pain in rats via DP2 receptor in the spinal cord.
Hyperemia
A urine biomarker for severe OSA patients: lipocaline-type prostaglandin D synthase.
Hypersensitivity
Discovery of an Oral Potent Selective Inhibitor of Hematopoietic Prostaglandin D Synthase (HPGDS).
Hypersensitivity
Essential role for hematopoietic prostaglandin D2 synthase in the control of delayed type hypersensitivity.
Hypersensitivity
Identification of new inhibitors for human hematopoietic prostaglandin D2 synthase among FDA-approved drugs and other compounds.
Hypersensitivity
Improvement in the quality of hematopoietic prostaglandin D synthase crystals in a microgravity environment.
Hypersensitivity
Mechanism of metal activation of human hematopoietic prostaglandin D synthase.
Hypersensitivity
Role of TrkA signalling and mast cells in the initiation of osteoarthritis pain in the monoiodoacetate model.
Hypersensitivity
Structure-function analysis of human l-prostaglandin D synthase bound with fatty acid molecules.
Hypertension
Association of serum lipocalin-type prostaglandin D synthase levels with subclinical atherosclerosis in untreated asymptomatic subjects.
Hypertension
Brain Prostaglandin D2 Increases Neurogenic Pressor Activity and Mean Arterial Pressure in Angiotensin II-Salt Hypertensive Rats.
Hypertension
De novo synthesis, uptake and proteolytic processing of lipocalin-type prostaglandin D synthase, beta-trace, in the kidneys.
Hypertension
Elevated Serum Beta-Trace Protein Levels are Associated With the Presence of Atrial Fibrillation in Hypertension Patients.
Hypertension
Gene expression changes of prostanoid synthases in endothelial cells and prostanoid receptors in vascular smooth muscle cells caused by aging and hypertension.
Hypertension
High-sensitivity Troponin I Predicts Galectin-3 in Chronic Kidney Disease Patients.
Hypertension
Lipocalin-Like Prostaglandin D Synthase but Not Hemopoietic Prostaglandin D Synthase Deletion Causes Hypertension and Accelerates Thrombogenesis in Mice.
Hypertension
Post-translational modification regulates prostaglandin D2 synthase apoptotic activity: characterization by site-directed mutagenesis.
Hypertension
Prostaglandin D2 synthase inhibits the exaggerated growth phenotype of spontaneously hypertensive rat vascular smooth muscle cells.
Hypertension
Urinary excretions of lipocalin-type prostaglandin D2 synthase predict the development of proteinuria and renal injury in OLETF rats.
Hypertension, Pregnancy-Induced
Serum Beta-Trace Protein as a Novel Predictor of Pregnancy-Induced Hypertension.
Hypertension, Pulmonary
Niacin Attenuates Pulmonary Hypertension Through H-PGDS in Macrophages.
Hypoglycemia
Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo.
Hypothyroidism
Hypothyroidism alters the expression of prostaglandin D2 synthase/beta trace in specific areas of the developing rat brain.
Hypoxia-Ischemia, Brain
Early induction of neuronal lipocalin-type prostaglandin D synthase after hypoxic-ischemic injury in developing brains.
Idiopathic Hypersomnia
Lipocalin-type prostaglandin D synthase levels increase in patients with narcolepsy and idiopathic hypersomnia.
Infarction, Middle Cerebral Artery
Lipocalin-prostaglandin D synthase is a critical beneficial factor in transient and permanent focal cerebral ischemia.
Infections
Chicken innate immune response to oral infection with Salmonella enterica serovar Enteritidis.
Infections
Perfusion culture of baculovirus-infected BTI-Tn-5B1-4 insect cells: a method to restore cell-specific beta-trace glycoprotein productivity at high cell density.
Infections
PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-? production.
Infections
Targeted transcript analysis revealed association of suboptimal expression of certain endometrial immunity-related genes with disparate uterine diseases in zebu cows.
Infections
The vitamin D receptor and inducible nitric oxide synthase associated pathways in acquired resistance to Cooperia oncophora infection in cattle.
Infertility
Relationship between contents of lipocalin-type prostaglandin D synthase on the surface of infertility sperm and in seminal plasma.
Inflammatory Bowel Diseases
Haplotype of prostaglandin synthase 2/cyclooxygenase 2 is involved in the susceptibility to inflammatory bowel disease.
Insulin Resistance
Accelerated glucose intolerance, nephropathy, and atherosclerosis in prostaglandin D2 synthase knock-out mice.
Insulin Resistance
L-PGDS-produced PGD2 in premature, but not in mature, adipocytes increases obesity and insulin resistance.
Insulin Resistance
Lipocalin-type Prostaglandin D2 Synthase appears to function as a Novel Adipokine Preventing Adipose Dysfunction in response to a High Fat Diet.
Insulin Resistance
Lipocalin-type prostaglandin D2 synthase deletion induces dyslipidemia and non-alcoholic fatty liver disease.
Insulin Resistance
Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo.
Insulin Resistance
Prostaglandin profiling reveals a role for haematopoietic prostaglandin D synthase in adipose tissue macrophage polarisation in mice and humans.
Insulin Resistance
Targeting steroid receptor coactivator 1 with antisense oligonucleotides increases insulin-stimulated skeletal muscle glucose uptake in chow-fed and high-fat-fed male rats.
Insulin Resistance
The lipocalin-type prostaglandin D2 synthase knockout mouse model of insulin resistance and obesity demonstrates early hypothalamic-pituitary-adrenal axis hyperactivity.
Insulin Resistance
The lipocalins retinol-binding protein-4, lipocalin-2 and lipocalin-type prostaglandin D2-synthase correlate with markers of inflammatory activity, alcohol intake and blood lipids, but not with insulin sensitivity in metabolically healthy 58-year-old Swedish men.
Intestinal Volvulus
A dominant role for extracellular glutathione S-transferase from Onchocerca volvulus is the production of prostaglandin D2.
Intracranial Aneurysm
Acute and transient increase of lipocalin-type prostaglandin D synthase (beta-trace) level in cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage.
Intracranial Hypotension
Spontaneous intracranial hypotension is diagnosed by a combination of lipocalin-type prostaglandin D synthase and brain-type transferrin in cerebrospinal fluid.
Ischemic Stroke
L-PGDS Mediates Vagus Nerve Stimulation-Induced Neuroprotection in a Rat Model of Ischemic Stroke by Suppressing the Apoptotic Response.
Job Syndrome
Increased in vitro bone resorption by monocytes in the hyper-immunoglobulin E syndrome.
Joint Diseases
Prostaglandin D(2) in inflammatory arthritis and its relation with synovial fluid dendritic cells.
Kidney Diseases
Urinary excretions of lipocalin-type prostaglandin D synthase predict renal injury in type-2 diabetes: a cross-sectional and prospective multicentre study.
Kidney Failure, Chronic
Comparison of measured GFR, serum creatinine, cystatin C, and beta-trace protein to predict ESRD in African Americans with hypertensive CKD.
Kidney Failure, Chronic
Development and evaluation of a practical ELISA for human urinary lipocalin-type prostaglandin D synthase.
Kidney Failure, Chronic
Molecular characterization of beta-trace protein in human serum and urine: a potential diagnostic marker for renal diseases.
Leiomyoma
DNA microarray data integration by ortholog gene analysis reveals potential molecular mechanisms of estrogen-dependent growth of human uterine fibroids.
Leiomyoma
MAPK14 cooperates with MAPK3/1 to regulate endothelin-1-mediated prostaglandin synthase 2 induction and survival in leiomyoma but not in normal myometrial cells.
Leukemia
Effects of anticholinergic agent on miRNA profiles and transcriptomes in a murine model of allergic rhinitis.
Leukocytosis
Immunoglobulin abnormalities in multiple sclerosis. Relation to clinical parameters: disability, duration and age of onset.
Leukodystrophy, Globoid Cell
Lipocalin-type prostaglandin D synthase (beta-trace) is upregulated in the alphaB-crystallin-positive oligodendrocytes and astrocytes in the chronic multiple sclerosis.
Leukodystrophy, Globoid Cell
Lipocalin-type prostaglandin D synthase is up-regulated in oligodendrocytes in lysosomal storage diseases and binds gangliosides.
Leukodystrophy, Globoid Cell
Prostaglandin D2-mediated microglia/astrocyte interaction enhances astrogliosis and demyelination in twitcher.
Liver Diseases
Lipocalin-type prostaglandin D2 synthase deletion induces dyslipidemia and non-alcoholic fatty liver disease.
Liver Diseases
Trial and error investigational drug induced liver injury, a case series report.
Lung Injury
Retrovirally introduced prostaglandin D2 synthase suppresses lung injury induced by bleomycin.
Lung Neoplasms
A genetic polymorphism in prostaglandin synthase 2 (8473, T-->C) and the risk of lung cancer.
Lung Neoplasms
Characterization of the prostaglandin biosynthetic pathway in non-small cell lung cancer: a comparison with small cell lung cancer and correlation with angiogenesis, angiogenic factors and metastases.
Lung Neoplasms
Diminished lipocalin-type prostaglandin D(2) synthase expression in human lung tumors.
Lung Neoplasms
Overexpression of a cell adhesion molecule, TSLC1, as a possible molecular marker for acute-type adult T-cell leukemia.
Lupus Nephritis
Urinary prostaglandin D synthase as biomarker in lupus nephritis: a longitudinal study.
Lupus Nephritis
Urine proteome scans uncover total urinary protease, prostaglandin D synthase, serum amyloid P, and superoxide dismutase as potential markers of lupus nephritis.
Lymphoma, B-Cell
Importance of the GDF9 signaling pathway on cumulus cell expansion and oocyte competency in sheep.
Lysosomal Storage Diseases
Lipocalin-type prostaglandin D synthase is up-regulated in oligodendrocytes in lysosomal storage diseases and binds gangliosides.
Mastitis
Lipocalin-type prostaglandin D synthase in milk: a new biomarker for bovine mastitis.
Mastocytoma
Effect of sodium n-butyrate on induction of prostaglandin synthase activity in cloned mastocytoma P-815 2-E-6 cells.
Mastocytoma
Inhibitors of lipoxygenase have antiproliferative effects on P815 murine mastocytoma cells.
Mastocytoma
Structural and functional characterization of HQL-79, an orally selective inhibitor of human hematopoietic prostaglandin D synthase.
Medulloblastoma
Proteomic profiling of cerebrospinal fluid identifies prostaglandin D2 synthase as a putative biomarker for pediatric medulloblastoma: A pediatric brain tumor consortium study.
Melanoma
Identify the signature genes for diagnose of uveal melanoma by weight gene co-expression network analysis.
Melanoma
Increased inflammatory lipid metabolism and anaplerotic mitochondrial activation follow acquired resistance to vemurafenib in BRAF-mutant melanoma cells.
Melanoma
Lipocalin-type prostaglandin D synthase as a marker for the proliferative potential of melanocyte-lineage cells in the human skin.
Melanoma
Lipocalin-type prostaglandin D synthase as a regulator of the retinoic acid signaling in melanocytes.
Melanoma, Experimental
Lipocalin-type prostaglandin D synthase as a melanocyte marker regulated by MITF.
Meningioma
Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes.
Meningioma
On Arachnoid Villi and Meningiomas: Functional Implication of Ultrastructure, Cell Adhesion Mechanisms, and Extracellular Matrix Composition.
Meningioma
Optic nerve compartment syndrome in a patient with optic nerve sheath meningioma.
Meningioma
Prostaglandin D synthase (beta-trace) in human arachnoid and meningioma cells: roles as a cell marker or in cerebrospinal fluid absorption, tumorigenesis, and calcification process.
Meningitis
Beta-trace protein concentration in cerebrospinal fluid is decreased in patients with bacterial meningitis.
Meningitis, Bacterial
Beta-trace protein concentration in cerebrospinal fluid is decreased in patients with bacterial meningitis.
Meningitis, Bacterial
Beta-trace protein in cerebrospinal fluid: a blood-CSF barrier-related evaluation in neurological diseases.
Meningitis, Bacterial
Beta-trace protein test: new guidelines for the reliable diagnosis of cerebrospinal fluid fistula.
Meningitis, Viral
Prostaglandin D synthase concentration in cerebrospinal fluid and serum of patients with neurological disorders.
Meningoencephalitis
Beta-trace protein concentration in cerebrospinal fluid is decreased in patients with bacterial meningitis.
Meningoencephalitis
Beta-trace protein in cerebrospinal fluid: a blood-CSF barrier-related evaluation in neurological diseases.
Meningoencephalitis
[Beta trace protein in the cerebrospinal fluid and serum in meningoencephalitis]
Metabolic Syndrome
Adipocyte Mineralocorticoid Receptor Activation Leads to Metabolic Syndrome and Induction of Prostaglandin D2 Synthase.
Metabolic Syndrome
Lipocalin-type Prostaglandin D2 Synthase appears to function as a Novel Adipokine Preventing Adipose Dysfunction in response to a High Fat Diet.
Microphthalmos
High beta-trace protein concentration in the fluid of an orbital cyst associated with bilateral colobomatous microphthalmos.
Multiple Sclerosis
Beta-trace protein in cerebrospinal fluid: a blood-CSF barrier-related evaluation in neurological diseases.
Multiple Sclerosis
Capillary-zone electrophoretic analyses of the proteins and amino acid components in cerebrospinal fluid of central nervous system diseases.
Multiple Sclerosis
Immunoglobulin abnormalities in multiple sclerosis. Relation to clinical parameters: disability, duration and age of onset.
Multiple Sclerosis
Lipocalin-type prostaglandin D synthase (beta-trace) is upregulated in the alphaB-crystallin-positive oligodendrocytes and astrocytes in the chronic multiple sclerosis.
Multiple Sclerosis
Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination.
Multiple Sclerosis
Oligoclonal IgG and free chains in multiple sclerosis demonstrated by thin-layer polyacrylamide gel isoelectric focusing and immunofixation.
Multiple Sclerosis
Prostaglandin D synthase concentration in cerebrospinal fluid and serum of patients with neurological disorders.
Multiple Sclerosis
Prostaglandin D synthase isoforms from cerebrospinal fluid vary with brain pathology.
Multiple Sclerosis
Quantification of prostaglandin D synthetase in cerebrospinal fluid: a potential marker for brain tumor.
Muscular Dystrophies
Induction of hematopoietic prostaglandin D synthase in hyalinated necrotic muscle fibers: its implication in grouped necrosis.
Muscular Dystrophy, Duchenne
Development of a Hematopoietic Prostaglandin D Synthase-Degradation Inducer.
Muscular Dystrophy, Duchenne
Induction of hematopoietic prostaglandin D synthase in hyalinated necrotic muscle fibers: its implication in grouped necrosis.
Muscular Dystrophy, Duchenne
Inhibition of prostaglandin D synthase suppresses muscular necrosis.
Narcolepsy
Lipocalin-type prostaglandin D synthase levels increase in patients with narcolepsy and idiopathic hypersomnia.
Narcolepsy
Narcolepsy increased L-PGDS (beta-trace) levels correlate with excessive daytime sleepiness but not with cataplexy.
Nasal Obstruction
Inhibition of hematopoietic prostaglandin D synthase improves allergic nasal blockage in guinea pigs.
Nasal Obstruction
Potential synergistic effects of novel hematopoietic prostaglandin D synthase inhibitor TAS-205 and different types of anti-allergic medicine on nasal obstruction in a Guinea pig model of experimental allergic rhinitis.
Nasal Obstruction
Role of hematopoietic prostaglandin D synthase in biphasic nasal obstruction in guinea pig model of experimental allergic rhinitis.
Nasal Polyps
Expression and Characterization of PGD(2) Receptors in Chronic Rhinosinusitis: Modulation of DP and CRTH2 by PGD(2).
Nasal Polyps
Expression of prostaglandin D2 synthase in activated eosinophils in nasal polyps.
Nasal Polyps
Steroids Inhibit Eosinophil Accumulation and Downregulate Hematopoietic Chemotaxic Prostaglandin D2 Receptor in Aspirin-Exacerbated Respiratory Disease.
Nasal Polyps
The ERK MAPK/RSK1 cascade phosphorylates CREB to induce MUC5B gene expression via DP1 receptor signaling.
Nasal Polyps
Thymic stromal lymphopoietin controls prostaglandin D2 generation in patients with aspirin-exacerbated respiratory disease.
Neoplasm Metastasis
Nephroblastoma overexpressed gene (NOV) enhances cell motility and COX-2 upregulation of human osteosarcoma involves ?v?5 integrin, ILK and AP-1-dependent pathways.
Neoplasm Metastasis
Nephroblastoma overexpressed gene (NOV) enhances RCC cell motility through upregulation of ICAM-1 and COX-2 expression via Akt pathway.
Neoplasms
18F-glutathione conjugate as a PET tracer for imaging tumors that overexpress L-PGDS enzyme.
Neoplasms
A common single-nucleotide polymorphism in cyclooxygenase-2 disrupts microRNA-mediated regulation.
Neoplasms
Biological markers of risk in nipple aspirate fluid are associated with residual cancer and tumour size.
Neoplasms
Comparative Proteomics Analysis of Urine Reveals Down-Regulation of Acute Phase Response Signaling and LXR/RXR Activation Pathways in Prostate Cancer.
Neoplasms
Cyclooxygenase-2 expression increases with the stage and grade in transitional cell carcinoma of the urinary bladder.
Neoplasms
Cyclooxygenase-2 expression: a potential prognostic and predictive marker for high-grade ductal carcinoma in situ of the breast.
Neoplasms
Dexamethasone induces lipocalin-type prostaglandin D synthase gene expression in mouse neuronal cells.
Neoplasms
Diminished lipocalin-type prostaglandin D(2) synthase expression in human lung tumors.
Neoplasms
Expression and biological role of the prostaglandin D synthase/SOX9 pathway in human ovarian cancer cells.
Neoplasms
Expression of two WFDC1/ps20 isoforms in prostate stromal cells induces paracrine apoptosis through regulation of PTGS2/COX-2.
Neoplasms
Hematopoietic prostaglandin D synthase (HPGDS): A high stability, Val187Ile isoenzyme common among African Americans and its relationship to risk for colorectal cancer.
Neoplasms
Hematopoietic prostaglandin D synthase suppresses intestinal adenomas in ApcMin/+ mice.
Neoplasms
HER2/neu-induced mammary tumorigenesis and angiogenesis are reduced in cyclooxygenase-2 knockout mice.
Neoplasms
High dietary niacin may increase prostaglandin formation but does not increase tumor formation in apc (min/+) mice.
Neoplasms
Identification and functional analysis of the risk microRNAs associated with cerebral low-grade glioma prognosis.
Neoplasms
Importance of the GDF9 signaling pathway on cumulus cell expansion and oocyte competency in sheep.
Neoplasms
Inflammation, reproduction, cancer and all that.... The regulation and role of the inducible prostaglandin synthase.
Neoplasms
Inhibition of Opisthorchis felineus glutathione-dependent prostaglandin synthase by resveratrol correlates with attenuation of cholangiocyte neoplasia in a hamster model of opisthorchiasis.
Neoplasms
Intestinal tumor suppression in Apc(Min/+) mice by prostaglandin D2 receptor PTGDR.
Neoplasms
Leptomycin B, an inhibitor of the nuclear export receptor CRM1, inhibits COX-2 expression.
Neoplasms
Macrophages programmed by apoptotic cells promote angiogenesis via prostaglandin E2.
Neoplasms
Mast cell-derived prostaglandin D2 inhibits colitis and colitis-associated colon cancer in mice.
Neoplasms
Metabolic alterations of zinc and prostaglandins in both human and animal colonic tumor cells.
Neoplasms
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase regulates levels of bioactive lipids in non-small cell lung cancer.
Neoplasms
Nephroblastoma overexpressed gene (NOV) enhances cell motility and COX-2 upregulation of human osteosarcoma involves ?v?5 integrin, ILK and AP-1-dependent pathways.
Neoplasms
Nephroblastoma overexpressed gene (NOV) enhances RCC cell motility through upregulation of ICAM-1 and COX-2 expression via Akt pathway.
Neoplasms
Oocyte-secreted factor activation of SMAD 2/3 signaling enables initiation of mouse cumulus cell expansion.
Neoplasms
Overexpression of a cell adhesion molecule, TSLC1, as a possible molecular marker for acute-type adult T-cell leukemia.
Neoplasms
Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice.
Neoplasms
Overexpression of protein kinase C-delta plays a crucial role in interleukin-6-producing pheochromocytoma presenting with acute inflammatory syndrome: a case report.
Neoplasms
PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2.
Neoplasms
Prostaglandin D2 synthase/prostaglandin D2/TWIST2 signaling inhibits breast cancer proliferation.
Neoplasms
Prostaglandin synthases influence thyroid follicular cell proliferation but not carcinogenesis in rats initiated with N-bis(2-hydroxypropyl)nitrosamine.
Neoplasms
Proteomic profiling of cerebrospinal fluid identifies prostaglandin D2 synthase as a putative biomarker for pediatric medulloblastoma: A pediatric brain tumor consortium study.
Neoplasms
SNX10 and PTGDS are associated with the progression and prognosis of cervical squamous cell carcinoma.
Neoplasms
Suppression of prostate tumor cell growth by stromal cell prostaglandin D synthase-derived products.
Neoplasms
Synergism in the repression of COX-2- and TNFalpha-induction in platelet activating factor-stressed human neural cells.
Neoplasms
Versican expression level in cumulus cells is associated with human oocyte developmental competence.
Neoplastic Processes
Cyclooxygenase 2 expression in nasopharyngeal carcinoma: immunohistochemical findings and potential implications.
Nervous System Diseases
18F-glutathione conjugate as a PET tracer for imaging tumors that overexpress L-PGDS enzyme.
Nervous System Diseases
Budesonide epimer R, LAU-8080 and phenyl butyl nitrone synergistically repress cyclooxygenase-2 induction in [IL-1beta+Abeta42]-stressed human neural cells.
Nervous System Diseases
Charge microheterogeneity of the beta-trace proteins (lipocalin-type prostaglandin D synthase) in the cerebrospinal fluid of patients with neurological disorders analyzed by capillary isoelectrofocusing.
Nervous System Diseases
Plasma prostaglandin D2 synthase levels in sleep and neurological diseases.
Nervous System Diseases
Prostaglandin D synthase concentration in cerebrospinal fluid and serum of patients with neurological disorders.
Nervous System Diseases
Prostaglandin D2 synthase and its post-translational modifications in neurological disorders.
Nervous System Diseases
Sodium dodecyl sulfate-capillary gel electrophoretic analysis of molecular mass microheterogeneity of beta-trace protein in cerebrospinal fluid from patients with central nervous system diseases.
Nervous System Diseases
[Structure, localization and characterization of lipocalin-type prostaglandin D synthase]
Neural Tube Defects
Comparison of alphafetoprotein and beta-trace protein in the antenatal diagnosis of anencephaly and spina bifida.
Neural Tube Defects
Prenatal detection of neural tube defects. Comparison between alpha-fetoprotein and beta-trace protein assays.
Neuralgia
Exploration of candidate serum biomarkers potentially related to the chronic pain condition in Medication-overuse headache.
Neuralgia
Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice.
Neuralgia
Prostaglandin D2 contributes to cisplatin-induced neuropathic pain in rats via DP2 receptor in the spinal cord.
Neuroblastoma
Lipocalin-type prostaglandin D synthase protects against oxidative stress-induced neuronal cell death.
Neurodegenerative Diseases
Lipocalin-type prostaglandin D synthase protects against oxidative stress-induced neuronal cell death.
Neurodegenerative Diseases
Narcolepsy increased L-PGDS (beta-trace) levels correlate with excessive daytime sleepiness but not with cataplexy.
Neurodegenerative Diseases
Plasma prostaglandin D2 synthase levels in sleep and neurological diseases.
Neurodegenerative Diseases
Prevention of paraquat-induced apoptosis in human neuronal SH-SY5Y cells by lipocalin-type prostaglandin D synthase.
Neurodegenerative Diseases
Prostaglandin D synthase concentration in cerebrospinal fluid and serum of patients with neurological disorders.
Neurofibromatoses
Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes.
Neurofibromatosis 2
Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes.
Neuroinflammatory Diseases
Genetic and Histological Alterations Reveal Key Role of Prostaglandin Synthase and Cyclooxygenase 1 and 2 in Traumatic Brain Injury-Induced Neuroinflammation in the Cerebral Cortex of Rats Exposed to Moderate Fluid Percussion Injury.
Neuroinflammatory Diseases
Hematopoietic prostaglandin D synthase and DP1 receptor are selectively upregulated in microglia and astrocytes within senile plaques from human patients and in a mouse model of Alzheimer disease.
Neuroinflammatory Diseases
Lipocalin-type prostaglandin D2 synthase regulates glial cell migration and morphology through marcks: prostaglandin D2-independent effects.
Neuroinflammatory Diseases
Unexpected role of lipocalin-type prostaglandin D synthase in brain: Regulation of glial cell migration and morphology.
Neuroma, Acoustic
beta-trace protein (prostaglandin D synthase) - a stable and reliable protein in perilymph.
Nevus
Lipocalin-type prostaglandin D synthase as a marker for the proliferative potential of melanocyte-lineage cells in the human skin.
Nevus, Epithelioid and Spindle Cell
Lipocalin-type prostaglandin D synthase as a marker for the proliferative potential of melanocyte-lineage cells in the human skin.
Niemann-Pick Diseases
Relationship between HSP90a, NPC2 and L-PGDS proteins to boar semen freezability.
Non-alcoholic Fatty Liver Disease
Lipocalin-type Prostaglandin D2 Synthase appears to function as a Novel Adipokine Preventing Adipose Dysfunction in response to a High Fat Diet.
Non-alcoholic Fatty Liver Disease
Lipocalin-type prostaglandin D2 synthase deletion induces dyslipidemia and non-alcoholic fatty liver disease.
Obesity
A structure-function approach identifies L-PGDS as a mediator responsible for glucocorticoid-induced leptin expression in adipocytes.
Obesity
Central nervous system lipocalin-type prostaglandin D2-synthase (L-PGDS) is correlated with orexigenic neuropeptides, visceral adiposity and markers of the hypothalamic-pituitary-adrenal axis in obese humans.
Obesity
L-PGDS-produced PGD2 in premature, but not in mature, adipocytes increases obesity and insulin resistance.
Obesity
Lipocalin-type Prostaglandin D2 Synthase appears to function as a Novel Adipokine Preventing Adipose Dysfunction in response to a High Fat Diet.
Obesity
Lipocalin-type prostaglandin D2 synthase deletion induces dyslipidemia and non-alcoholic fatty liver disease.
Obesity
Proliferation and differentiation of adipose tissue in prolonged lean and obese critically ill patients.
Obesity
The lipocalin-type prostaglandin D2 synthase knockout mouse model of insulin resistance and obesity demonstrates early hypothalamic-pituitary-adrenal axis hyperactivity.
Obesity, Abdominal
Central nervous system lipocalin-type prostaglandin D2-synthase (L-PGDS) is correlated with orexigenic neuropeptides, visceral adiposity and markers of the hypothalamic-pituitary-adrenal axis in obese humans.
Obstetric Labor, Premature
Efficacy of the selective prostaglandin synthase type 2 inhibitor nimesulide in blocking basal prostaglandin production and delaying glucocorticoid-induced premature labor in sheep.
Obstetric Labor, Premature
Inhibition of premature labor in sheep by a combined treatment of nimesulide, a prostaglandin synthase type 2 inhibitor, and atosiban, an oxytocin receptor antagonist.
Obstetric Labor, Premature
Prostaglandins and prostanoid receptors in human pregnancy and parturition.
Oligospermia
Biomarkers for demographic research: sperm counts and other male infertility biomarkers.
Opisthorchiasis
Inhibition of Opisthorchis felineus glutathione-dependent prostaglandin synthase by resveratrol correlates with attenuation of cholangiocyte neoplasia in a hamster model of opisthorchiasis.
Optic Nerve Diseases
L-PGDS (betatrace protein) inhibits astrocyte proliferation and mitochondrial ATP production in vitro.
Optic Neuritis
Quantification of prostaglandin D synthetase in cerebrospinal fluid: a potential marker for brain tumor.
Osteoarthritis
Expression of peroxisome proliferator-activated receptors ?, ?, ?, and H- and L-prostaglandin D synthase during osteoarthritis in the spontaneous hartley guinea pig and experimental dog models.
Osteoarthritis
Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage.
Osteoarthritis
L-PGDS deficiency accelerated the development of naturally occurring age-related osteoarthritis.
Osteoarthritis
Role of Lipocalin-Type Prostaglandin D Synthase in Experimental Osteoarthritis.
Ovarian Neoplasms
Stimulation of lipocalin-type prostaglandin D synthase by retinoic acid coincides with inhibition of cell proliferation in human 3AO ovarian cancer cells.
Parkinson Disease
A Parkinson's disease gene, DJ-1, regulates anti-inflammatory roles of astrocytes through prostaglandin D2 synthase expression.
Parkinson Disease
Prostaglandin D synthase isoforms from cerebrospinal fluid vary with brain pathology.
Peripheral Nerve Injuries
Prostaglandin D2 synthase modulates macrophage activity and accumulation in injured peripheral nerves.
Pleural Effusion
Beta-Trace Protein in Ascites and Pleural Effusions: Limits of CSF Leakage Detection.
Pleural Effusion
Pleural effusion: beta-trace protein in diagnosing ventriculoperitoneal shunt complications.
Pleural Effusion
Subarachnoid-pleural fistula as a complication of malignant pleural mesothelioma.
Pleural Effusion
Subarachnoidal-pleural fistula (SAPF) as an unusual cause of persistent pleural effusion. Beta-trace protein as a marker for SAPF. Case report and review of the literature.
Pneumonia
Epithelial cell-derived prostaglandin D2 inhibits chronic allergic lung inflammation in mice.
Pneumonia
Lipopolysaccharide-dependent interaction between PU.1 and cJun determines production of lipocalin-type prostaglandin D synthase and prostaglandin D2 in macrophages.
Pneumonia
Nrf2 is essential for the expression of lipocalin-prostaglandin D synthase induced by prostaglandin D2.
Pneumonia
Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice.
Pneumonia
Prostaglandin D2 Attenuates Bleomycin-Induced Lung Inflammation and Pulmonary Fibrosis.
Pneumonia
Prostaglandin D2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells.
Polymyositis
Induction of hematopoietic prostaglandin D synthase in hyalinated necrotic muscle fibers: its implication in grouped necrosis.
Polyneuropathies
Decreased intrathecal synthesis of prostaglandin D2 synthase in the cerebrospinal fluid of patients with acute inflammatory demyelinating polyneuropathy.
Pregnancy Complications
Gene expression profiling of human decidual macrophages: evidence for immunosuppressive phenotype.
Premature Birth
Role of Lipocalin-type prostaglandin D2 synthase (L-PGDS) and its metabolite, prostaglandin D2, in preterm birth.
prostaglandin-d synthase deficiency
Epithelial cell-derived prostaglandin D2 inhibits chronic allergic lung inflammation in mice.
prostaglandin-d synthase deficiency
Hematopoietic prostaglandin D synthase-derived prostaglandin D2 ameliorates adjuvant-induced joint inflammation in mice.
prostaglandin-d synthase deficiency
Knockout of the l-pgds gene aggravates obesity and atherosclerosis in mice.
prostaglandin-d synthase deficiency
L-PGDS deficiency accelerated the development of naturally occurring age-related osteoarthritis.
prostaglandin-d synthase deficiency
L-PGDS-derived PGD2 attenuates acute lung injury by enhancing endothelial barrier formation.
prostaglandin-d synthase deficiency
Mast cell-derived prostaglandin D2 inhibits colitis and colitis-associated colon cancer in mice.
prostaglandin-d synthase deficiency
PGD2 deficiency exacerbates food antigen-induced mast cell hyperplasia.
prostaglandin-d synthase deficiency
Prostagladin D2 is a mast cell-derived antiangiogenic factor in lung carcinoma.
prostaglandin-d synthase deficiency
Prostaglandin D2 Attenuates Bleomycin-Induced Lung Inflammation and Pulmonary Fibrosis.
Prostatic Hyperplasia
The prostaglandin synthases, COX-2 and L-PGDS, mediate prostate hyperplasia induced by low-dose bisphenol A.
Prostatic Neoplasms
A gene signature identified using a mouse model of androgen receptor-dependent prostate cancer predicts biochemical relapse in human disease.
Proteinuria
Lipocalin-type prostaglandin D synthase in urine in adriamycin-induced nephropathy of mice.
Proteinuria
Urinary excretions of lipocalin-type prostaglandin D2 synthase predict the development of proteinuria and renal injury in OLETF rats.
Proteinuria
Urinary prostaglandin D synthase (beta-trace) excretion increases in the early stage of diabetes mellitus.
Pulmonary Disease, Chronic Obstructive
Genes and Gene Ontologies Common to Airflow Obstruction and Emphysema in the Lungs of Patients with COPD.
Pulmonary Disease, Chronic Obstructive
Molecular markers of type 2 airway inflammation are similar between eosinophilic severe asthma and eosinophilic chronic obstructive pulmonary disease.
Pulmonary Embolism
Lipocalin-type prostaglandin D synthase levels are associated with the severity of pulmonary embolism.
Pulmonary Fibrosis
Prostaglandin D2 Attenuates Bleomycin-Induced Lung Inflammation and Pulmonary Fibrosis.
Renal Insufficiency
Beta-trace protein test: new guidelines for the reliable diagnosis of cerebrospinal fluid fistula.
Renal Insufficiency
Contribution of prostaglandin D2 synthase to progression of renal failure and dialysis dementia.
Renal Insufficiency
Highly elevated levels of prostaglandin D synthase in the serum of patients with renal failure.
Renal Insufficiency
Urinary prostaglandin D synthase (beta-trace) excretion increases in the early stage of diabetes mellitus.
Renal Insufficiency
[Functional analyses of lipocalin-type and hematopoietic prostaglandin D synthases]
Renal Insufficiency, Chronic
Evaluation of renal damage by urinary beta-trace protein in patients with chronic kidney disease.
Renal Insufficiency, Chronic
Non-GFR Determinants of Low-Molecular-Weight Serum Protein Filtration Markers in the Elderly: AGES-Kidney and MESA-Kidney.
Renal Insufficiency, Chronic
SERUM AND URINARY MARKERS OF EARLY IMPAIRMENT OF GFR IN CHRONIC KIDNEY DISEASE PATIENTS: DIAGNOSTIC ACCURACY OF URINARY BETA-TRACE PROTEIN.
Renal Insufficiency, Chronic
Serum creatinine, cystatin C, and beta-trace protein in diagnostic staging and predicting progression of primary nondiabetic chronic kidney disease.
Renal Insufficiency, Chronic
Urinary beta-trace protein as a tubular marker of renal dysfunction in patients with chronic kidney disease.
Retinal Detachment
Lipocalin-like prostaglandin D synthase in subretinal fluid of detached retinas in humans.
Retinal Perforations
Differential expression of vitreous proteins in proliferative diabetic retinopathy.
Rhinitis
Therapeutic Potential of Hematopoietic Prostaglandin D2 Synthase in Allergic Inflammation.
Rhinitis, Allergic
Inhibition of hematopoietic prostaglandin D synthase improves allergic nasal blockage in guinea pigs.
Rhinitis, Allergic
Potential synergistic effects of novel hematopoietic prostaglandin D synthase inhibitor TAS-205 and different types of anti-allergic medicine on nasal obstruction in a Guinea pig model of experimental allergic rhinitis.
Rhinitis, Allergic
Role of hematopoietic prostaglandin D synthase in biphasic nasal obstruction in guinea pig model of experimental allergic rhinitis.
Sandhoff Disease
Lipocalin-type prostaglandin D synthase is up-regulated in oligodendrocytes in lysosomal storage diseases and binds gangliosides.
Seizures
A gain-of-function study of amelioration of pentylenetetrazole-induced seizures by endogenous prostaglandin D2.
Seizures
Commentary on Kaushik et al.: Prostaglandin D2 is crucial for seizure suppression and postictal sleep. Novel evidence supporting a role for prostanoid receptors in seizure control.
Sepsis
High sPLA2-IIA level is associated with eicosanoid metabolism in patients with bacterial sepsis syndrome.
Skin Neoplasms
Adaptor protein p62 promotes skin tumor growth and metastasis and is induced by UVA radiation.
Sleep Apnea Syndromes
Prostaglandin D synthase (beta trace) levels in sleep apnea patients with and without sleepiness.
Sleep Deprivation
Narcolepsy increased L-PGDS (beta-trace) levels correlate with excessive daytime sleepiness but not with cataplexy.
Sleep Initiation and Maintenance Disorders
Inhibition of rat brain prostaglandin D synthase by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors.
Sleep Initiation and Maintenance Disorders
Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep.
Small Cell Lung Carcinoma
Characterization of the prostaglandin biosynthetic pathway in non-small cell lung cancer: a comparison with small cell lung cancer and correlation with angiogenesis, angiogenic factors and metastases.
Spinal Cord Injuries
Expression and detrimental role of hematopoietic prostaglandin D synthase in spinal cord contusion injury.
Spinal Dysraphism
Comparison of alphafetoprotein and beta-trace protein in the antenatal diagnosis of anencephaly and spina bifida.
Spinal Dysraphism
Measuring glomerular filtration rate with cystatin C and beta-trace protein in children with spina bifida.
Squamous Cell Carcinoma of Head and Neck
Lipocalin-type prostaglandin D synthase-derived PGD
Squamous Cell Carcinoma of Head and Neck
Simultaneous expression of cyclooxygenase-2 and microsomal prostaglandin E synthase in squamous cell carcinoma of the larynx.
Starvation
Enhancement of prostaglandin D(2) production through cyclooxygenase-2 and lipocalin-type prostaglandin D synthase by upstream stimulatory factor 1 in human brain-derived TE671 cells under serum starvation.
Stomach Neoplasms
Prostaglandin d synthase is a potential novel therapeutic agent for the treatment of gastric carcinomas expressing PPAR?
Stroke
Astrocyte-Derived Exosomes Treated With a Semaphorin 3A Inhibitor Enhance Stroke Recovery via Prostaglandin D2 Synthase.
Subarachnoid Hemorrhage
Acute and transient increase of lipocalin-type prostaglandin D synthase (beta-trace) level in cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Lipocalin-type prostaglandin D synthase scavenges biliverdin in the cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage.
Tay-Sachs Disease
Lipocalin-type prostaglandin D synthase is up-regulated in oligodendrocytes in lysosomal storage diseases and binds gangliosides.
Trichinellosis
Histochemical investigations of the biochemical defence mechanism in experimental trichinellosis: II. prostaglandin synthase activity.
Vitreoretinopathy, Proliferative
The upregulation of zinc finger protein 670 and prostaglandin D2 synthase in proliferative vitreoretinopathy.
Whooping Cough
Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways.
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
homologue of lipocalin-type prostaglandin synthase, weak enzymic activity
SwissProt
brenda
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Fujimori, K.; Inui, T.; Uodome, N.; Kadoyama, K.; Aritake, K.; Urade, Y.
Zebrafish and chicken lipocalin-type prostaglandin D synthase homologues: Conservation of mammalian gene structure and binding ability for lipophilic molecules, and difference in expression profile and enzyme activity
Gene
375
14-25
2006
Mus musculus, Gallus gallus (Q8QFM7), Gallus gallus, Danio rerio (Q8QGV4), Danio rerio
brenda
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Release 2023.1 (January 2023)
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