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Information on EC 5.3.3.12 - L-dopachrome isomerase

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EC Tree
     5 Isomerases
         5.3 Intramolecular oxidoreductases
             5.3.3 Transposing C=C bonds
                5.3.3.12 L-dopachrome isomerase
IUBMB Comments
A zinc enzyme. Stereospecific for L-dopachrome. Dopachrome methyl ester is a substrate, but dopaminochrome (2,3-dihydroindole-5,6-quinone) is not (see also EC 4.1.1.84, D-dopachrome decarboxylase).
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
trp-2, dopachrome tautomerase, d-dopachrome tautomerase, macrophage inhibitory factor, macrophage migration-inhibitory factor, dopachrome conversion factor, dopachrome oxidoreductase, tyrosine-related protein 2, dopachrome-rearranging enzyme, brown (b) locus protein, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-dopachrome = 5,6-dihydroxyindole-2-carboxylate
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PATHWAY SOURCE
PATHWAYS
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