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The enzyme appears in viruses and cellular organisms
Synonyms
d-ribose isomerase, ribose isomerase, more
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D-Ribose isomerase
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D-ribose ketol-isomerase
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Isomerase, ribose
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D-Ribose = D-ribulose
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intramolecular oxidoreduction
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D-ribose aldose-ketose-isomerase
Also acts on L-lyxose and L-rhamnose.
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D-Allose
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D-Lyxose
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L-lyxose
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L-Rhamnose
L-Rhamnulose
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additional information
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Substrates: enzyme of the pentose metabolism
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D-ribose
D-ribulose
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D-ribose
D-ribulose
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additional information
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Substrates: enzyme of the pentose metabolism
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Co2+
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divalent cation required, Km: 0.0004 mM
Mg2+
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divalent cation required, Km: 0.018 mM
Mn2+
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divalent cation required for activity, Mn2+ is the best activator, Km: 0.0001 mM
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6.5 - 9.5
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pH 6.5: about 45% of maximal activity, pH 9.5: about 55% of maximal activity
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brenda
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brenda
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brenda
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brenda
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brenda
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Highest Expressing Human Cell Lines
Cell Line Links
Gene Links
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145000 - 174000
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sedimentation equilibrium analysis
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tetramer
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4 * 42000-44000, SDS-PAGE in presence of Mn2+
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85
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60 min, complete loss of activity
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sensitive to freezing and thawing
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5°C, crystalline enzyme in 44% ammonium sulphate, stable for at least 1 month
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Izumori, K.; Mitchell, M.; Elbein, A.D.
Evidence that the isomerization of D-ribose and L-rhamnose is catalyzed by the same enzyme in Mycobacterium smegmatis
J. Bacteriol.
126
553-555
1976
Mycolicibacterium smegmatis
brenda
Izumori, K.; Rees, A.W.; Elbein, A.D.
Purification, crystallization, and properties of D-ribose isomerase from Mycobacterium smegmatis
J. Biol. Chem.
250
8085-8087
1975
Mycolicibacterium smegmatis
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Izumori, K.; Yamanaka, K.; Elbein, A.D.
Pentose metabolism in Mycobacterium smegmatis: specificity of induction of pentose isomerase
J. Bacteriol.
128
587-591
1976
Mycolicibacterium smegmatis
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Elbein, A.D.; Izumori, K.
D-Ribose isomerase
Methods Enzymol.
89
547-550
1982
Mycolicibacterium smegmatis
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Shukla, G.L.; Prabhu, K.A.
Studies on sugar isomerases of Lactobacillus sp.
J. Basic Microbiol.
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273-277
1985
Lactobacillus sp.
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brenda
Izumori, K.; Sugimoto, S.; Kraska, B.
Induction of D-ribose isomerase by L-ribose in Mycobacterium smegmatis
Agric. Biol. Chem.
44
223-225
1980
Mycolicibacterium smegmatis
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brenda
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