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Information on EC 5.2.1.8 - peptidylprolyl isomerase
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5.2.1.8 peptidylprolyl isomeraseIUBMB Comments
The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A. Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli. The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively.
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- 5.2.1.8
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cyclosporine
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immunophilins
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isomerization
- calcineurin
- isomerases
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ryanodine
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tetratricopeptide
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refolding
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- gapdh
-
co-chaperone
-
genorm
- dnak
-
anti-hcv
- ptp
- groel
- legionella
-
osteogenesis
-
sarcoplasmic
- translocase
-
heterocomplexes
- pneumophila
-
voltage-dependent
-
phosphorylation-dependent
- ns5a
- analysis
-
ca2+-induced
-
direct-acting
- sirolimus
-
csa-induced
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proline-directed
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bestkeeper
-
excitation-contraction
- medicine
- ribavirin
-
emmprin
-
normfinder
-
ribosome-associated
- agriculture
- pharmacology
The enzyme appears in viruses and cellular organisms
Synonyms
cyclophilin, cyclophilin a, fkbp12, ppiase, fkbp51, trigger factor, fkbp52, fk506-binding protein, peptidyl-prolyl isomerase, cyclophilin b, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
12 kDa FKBP
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12.6 kDa FKBP
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13 kDa FKBP
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15 kDa FKBP
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19 kDa FK506-binding protein
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22 kDa FK506-binding protein
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25 kDa FKBP
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27 kDa membrane protein
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36 kDa FK506 binding protein
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40 kDa thylakoid lumen PPIase
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40 kDa thylakoid lumen rotamase
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51 kDa FK506-binding protein
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52 kDa FK506 binding protein
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54 kDa progesterone receptor-associated immunophilin
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65 kDa FK506-binding protein
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CGI-124
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Chl-Mip
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CPH
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Cyclophilin
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Cyclophilin 18
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Cyclophilin 33
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Cyclophilin A
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Cyclophilin B
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Cyclophilin C
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Cyclophilin cyp2
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Cyclophilin homolog
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Cyclophilin ScCypA
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Cyclophilin ScCypB
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Cyclophilin-10
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Cyclophilin-11
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Cyclophilin-40
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Cyclophilin-60
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Cyclophilin-like protein Cyp-60
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Cyclophilin-related protein
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Cyclosporin A-binding protein
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CYP-40
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CYP-S1
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-
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Cyp3 PPIase
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CyPA
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CyPB
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Estrogen receptor binding cyclophilin
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FF1 antigen
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FKBP
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FKBP-12
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FKBP-12.6
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FKBP-13
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FKBP-15
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FKBP-19
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FKBP-21
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FKBP-22
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FKBP-23
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FKBP-25
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FKBP-36
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FKBP-51
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FKBP-70
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FKBP22
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FKBP52 protein
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FKBP54
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FKBP59
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FKBP65
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FKBP65RS
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HBI
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Histidine rich protein
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hPar14
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HSP binding immunophilin
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HSP90-binding immunophilin
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Immunophilin FKBP12
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Immunophilin FKBP12.6
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Immunophilin FKBP36
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Immunophilin FKBP65
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Isomerase, peptidylprolyl cis-trans
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Macrolide binding protein
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Macrophage infectivity potentiator
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MtFK
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Nucleolar proline isomerase
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p17.7
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P31
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P54
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p59 protein
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Par14
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Parvulin
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Parvulin 14
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Peptide bond isomerase
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Peptidyl-prolyl cis-trans isomerase
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Peptidyl-prolyl cis-trans isomerase plp
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Peptidyl-prolyl cis-trans isomerase surA
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Peptidyl-prolyl cis/trans isomerase EPVH
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Peptidylprolyl cis-trans isomerase
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PfCyP
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Planta-induced rust protein 28
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PPIase
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PPIase Pin1
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PPIase Pin4
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Proline rotamase
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Proteins, cyclophilins
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Proteins, specific or class, cyclophilins
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Rapamycin-binding protein
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Rapamycin-selective 25 kDa immunophilin
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Rotamase
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Rotamase Pin1
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Rotamase Pin4
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Rotamase plp
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S-cyclophilin
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S1205-06
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SCYLP
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SmCYP A
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SmCYP B
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Smp17.7
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SP18
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WHP
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SYSTEMATIC NAME
IUBMB Comments
Peptidylproline cis-trans-isomerase
The first type of this enzyme found [1] proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A. Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli. The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively.
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CAS REGISTRY NUMBER
COMMENTARY
95076-93-0
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
succinyl-Ala-Ala-(cis)-Pro-Phe-4-nitroanilide
succinyl-Ala-Ala-(trans)-Pro-Phe-4-nitroanilide
-
-
-
?
succinyl-Ala-Gly-(cis)-Pro-Phe-4-nitroanilide
succinyl-Ala-Gly-(trans)-Pro-Phe-4-nitroanilide
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-
-
?
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abortion, Spontaneous
Expression of FK506-binding protein 52 (FKBP52) in chorionic villi with early recurrent spontaneous abortion.
Abscess
Novel Regulation of Alpha-Toxin and the Phenol-Soluble Modulins by Peptidyl-Prolyl cis/trans Isomerase Enzymes in Staphylococcus aureus.
Acidosis
Cyclosporin A produces distal renal tubular acidosis by blocking peptidyl prolyl cis-trans isomerase activity of cyclophilin.
Acidosis, Renal Tubular
Cyclosporin A produces distal renal tubular acidosis by blocking peptidyl prolyl cis-trans isomerase activity of cyclophilin.
Acquired Immunodeficiency Syndrome
A COMPARISON OF RAPID DIAGNOSTIC TESTING (BY PLASMODIUM LACTATE DEHYDROGENASE), AND QUANTITATIVE BUFFY COAT TECHNIQUE IN MALARIA DIAGNOSIS IN CHILDREN.
Acquired Immunodeficiency Syndrome
Contribution of Cyclophilin A to determination of simian immunodeficiency virus tropism: a progress update.
Acquired Immunodeficiency Syndrome
Dynamics of Aromatic Side Chains in the Active Site of FKBP12.
Acquired Immunodeficiency Syndrome
Human Cyclophilin B forms part of a multi-protein complex during erythrocyte invasion by Plasmodium falciparum.
Acquired Immunodeficiency Syndrome
Regulatory polymorphisms in the cyclophilin A gene, PPIA, accelerate progression to AIDS.
Acquired Immunodeficiency Syndrome
Synthesis and evaluation of Glypsi(PO(2)R-N)Pro-containing pseudopeptides as novel inhibitors of the human cyclophilin hCyp-18.
Acquired Immunodeficiency Syndrome
[Experimental research of targeting hTERT gene inhibited in hepatocellular carcinoma therapy by RNA interference]
Acute Coronary Syndrome
Bromocriptine-induced coronary spasm caused acute coronary syndrome, which triggered its own clinical twin - takotsubo syndrome.
Acute Coronary Syndrome
CD137-CD137L interaction regulates atherosclerosis via cyclophilin A in apolipoprotein E-deficient mice.
Acute Coronary Syndrome
Decrease in plasma cyclophilin A concentration at 1 month after myocardial infarction predicts better left ventricular performance and synchronicity at 6 months: a pilot study in patients with ST elevation myocardial infarction.
Acute Coronary Syndrome
The clinical implications of increased cyclophilin A levels in patients with acute coronary syndromes.
Acute Kidney Injury
Cyclophilin A Promotes Inflammation in Acute Kidney Injury but Not in Renal Fibrosis.
Acute Kidney Injury
Cyclophilin D promotes tubular cell damage and the development of interstitial fibrosis in the obstructed kidney.
Acute Kidney Injury
Cyclophilin Inhibition Protects Against Experimental Acute Kidney Injury and Renal Interstitial Fibrosis.
Acute Kidney Injury
Diagnostic Performance of Cyclophilin A in Cardiac Surgery-Associated Acute Kidney Injury.
Acute Kidney Injury
Liver proteomics for therapeutic drug discovery: inhibition of the cyclophilin receptor CD147 attenuates sepsis-induced acute renal failure.
Acute Kidney Injury
Proximal tubule cyclophilin D regulates fatty acid oxidation in cisplatin-induced acute kidney injury.
Acute Kidney Injury
Regulation of necrotic cell death: p53, PARP1 and cyclophilin D-overlapping pathways of regulated necrosis?
Acute Kidney Injury
REGULATION OF THE MITOCHONDRIAL PERMEABILITY TRANSITION IN KIDNEY PROXIMAL TUBULES AND ITS ALTERATION DURING HYPOXIA/REOXYGENATION.
Acute Lung Injury
Lack of cyclophilin D protects against the development of acute lung injury in endotoxemia.
Adenocarcinoma
Androgen Receptor and Androgen-Responsive Gene FKBP5 Are Independent Prognostic Indicators for Esophageal Adenocarcinoma.
Adenocarcinoma
Citron Rho-Interacting Serine/Threonine Kinase Promotes HIF1a-CypA Signaling and Growth of Human Pancreatic Adenocarcinoma.
Adenocarcinoma
Expression and Significance of Cyclophilin J in Primary Gastric Adenocarcinoma.
Adenocarcinoma
Expression of Cyclophilin A in Gastric Adenocarcinoma Patients and Its Inverse Association with Local Relapses and Distant Metastasis.
Adenocarcinoma
FKBP10 functioned as a cancer-promoting factor mediates cell proliferation, invasion, and migration via regulating PI3K signaling pathway in stomach adenocarcinoma.
Adenocarcinoma
FKBP51 decreases cell proliferation and increases progestin sensitivity of human endometrial adenocarcinomas by inhibiting Akt.
Adenocarcinoma
FKBP51 expressed by both normal epithelial cells and adenocarcinoma of colon suppresses proliferation of colorectal adenocarcinoma.
Adenocarcinoma
Hypoxia induces cyclophilin B through the activation of transcription factor 6 in gastric adenocarcinoma cells.
Adenocarcinoma of Lung
A cyclophilin B gene encodes antigenic epitopes recognized by HLA-A24-restricted and tumor-specific CTLs.
Adenocarcinoma of Lung
Cyclophilin A expression and its prognostic significance in lung adenocarcinoma.
Adenocarcinoma of Lung
RNA interference-mediated gene silencing of cyclophilin A enhances the radiosensitivity of PAa human lung adenocarcinoma cells in vitro.
Adenocarcinoma of Lung
USP53 promotes apoptosis and inhibits glycolysis in lung adenocarcinoma through FKBP51-AKT1 signaling.
Adenoma
Apoptosis, mitosis and cyclophilin-40 expression in regressing peroxisome proliferator-induced adenomas.
Adenomatous Polyposis Coli
Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction.
Adrenal Insufficiency
Autoimmune polyglandular syndrome type 2 manifested as Hashimoto's thyroiditis and adrenocortical insufficiency, in Turner syndrome woman, with onset following introduction of treatment with recombinant human growth hormone.
Adrenoleukodystrophy
Cyclophilin D as a potential target for antioxidants in neurodegeneration: the X-ALD case.
Adrenoleukodystrophy
Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy.
Agammaglobulinemia
Naturally occurring mutation affecting the MyD88-binding site of TNFRSF13B impairs triggering of class switch recombination.
Albuminuria
Assessment of two novel renal tubular proteins in type 2 diabetic patients with nephropathy.
Alkalosis
[Nature of metabolic alkalosis in the postoperative period in patients with pulmonary tuberculosis]
Alopecia
More is Not Always Better in Hair Growth Factors. Epidermal Growth Factor: Hair Growth Factor Involved in Alopecia Areata Pathogenesis.
Alopecia Areata
More is Not Always Better in Hair Growth Factors. Epidermal Growth Factor: Hair Growth Factor Involved in Alopecia Areata Pathogenesis.
Alveolitis, Extrinsic Allergic
FK506-Binding Protein 13 Expression Is Upregulated in Interstitial Lung Disease and Correlated with Clinical Severity. A Potentially Protective Role.
Alzheimer Disease
A peptidyl-prolyl isomerase, FKBP12, accumulates in Alzheimer neurofibrillary tangles.
Alzheimer Disease
Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.
Alzheimer Disease
Caspase-cleaved Tau-D(421) is colocalized with the immunophilin FKBP52 in the autophagy-endolysosomal system of Alzheimer's disease neurons.
Alzheimer Disease
Circular RNA Cwc27 contributes to Alzheimer's disease pathogenesis by repressing Pur-? activity.
Alzheimer Disease
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease.
Alzheimer Disease
Cyclophilin D deficiency attenuates mitochondrial F1Fo ATP synthase dysfunction via OSCP in Alzheimer's disease.
Alzheimer Disease
Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model.
Alzheimer Disease
Decrease of the Immunophilin FKBP52 Accumulation in Human Brains of Alzheimer's Disease and FTDP-17.
Alzheimer Disease
Enhanced Sampling of Interdomain Motion Using Map-Restrained Langevin Dynamics and NMR: Application to Pin1.
Alzheimer Disease
FK506-binding protein 1b/12.6: A key to aging-related hippocampal Ca(2+) dysregulation?
Alzheimer Disease
FKBP12 regulates the localization and processing of amyloid precursor protein in human cell lines.
Alzheimer Disease
From steroid hormones to depressive states and senile dementias: New mechanistic, therapeutical and predictive approaches.
Alzheimer Disease
Granular expression of prolyl-peptidyl isomerase PIN1 is a constant and specific feature of Alzheimer's disease pathology and is independent of tau, A? and TDP-43 pathology.
Alzheimer Disease
High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules.
Alzheimer Disease
In Silico Insight into Potent of Anthocyanin Regulation of FKBP52 to Prevent Alzheimer's Disease.
Alzheimer Disease
In vitro study of interaction of 17?-hydroxysteroid dehydrogenase type 10 and cyclophilin D and its potential implications for Alzheimer's disease.
Alzheimer Disease
Insight into the structural stability of wild-type and histidine mutants in Pin1 by experimental and computational methods.
Alzheimer Disease
Interactions of 17?-Hydroxysteroid Dehydrogenase Type 10 and Cyclophilin D in Alzheimer's Disease.
Alzheimer Disease
Ionic Environment Affects Biomolecular Interactions of Amyloid-?: SPR Biosensor Study.
Alzheimer Disease
Ligand-based and structure-based investigation for Alzheimer's disease from traditional chinese medicine.
Alzheimer Disease
MicroRNA-511 Binds to FKBP5 mRNA, Which Encodes a Chaperone Protein, and Regulates Neuronal Differentiation.
Alzheimer Disease
Mitochondrial modulation of store-operated Ca(2+) entry in model cells of Alzheimer's disease.
Alzheimer Disease
Mitochondrial permeability transition pore in Alzheimer's disease: Cyclophilin D and amyloid beta.
Alzheimer Disease
Mitochondrial permeability transition pore is a potential drug target for neurodegeneration.
Alzheimer Disease
Pathological Role of Peptidyl-Prolyl Isomerase Pin1 in the Disruption of Synaptic Plasticity in Alzheimer's Disease.
Alzheimer Disease
Possible role of amyloid-beta, adenine nucleotide translocase and cyclophilin-D interaction in mitochondrial dysfunction of Alzheimer's disease.
Alzheimer Disease
Quantifying mRNA in postmortem human brain: influence of gender, age at death, postmortem interval, brain pH, agonal state and inter-lobe mRNA variance.
Alzheimer Disease
Relationship between Brain Tissue Changes and Blood Biomarkers of Cyclophilin A, Heme Oxygenase-1, and Inositol-Requiring Enzyme 1 in Patients with Alzheimer's Disease.
Alzheimer Disease
Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus.
Alzheimer Disease
Structural analysis of the mitotic regulator hPin1 in solution: insights into domain architecture and substrate binding.
Alzheimer Disease
The Caenorhabditis elegans parvulin gene subfamily and their expression under cold or heat stress along with the fkb subfamily.
Alzheimer Disease
The emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease.
Alzheimer Disease
Unlocking the Door to Neuronal Woes in Alzheimer's Disease: A? and Mitochondrial Permeability Transition Pore.
Amnesia, Transient Global
Increased incidence of transient global amnesia during the Covid-19 crisis?
Amyotrophic Lateral Sclerosis
Apoptosis-Inducing Factor and Cyclophilin A Cotranslocate to the Motor Neuronal Nuclei in Amyotrophic Lateral Sclerosis Model Mice.
Amyotrophic Lateral Sclerosis
Immunophilins in nervous system degeneration and regeneration.
Amyotrophic Lateral Sclerosis
Life span extension and reduced neuronal death after weekly intraventricular cyclosporin injections in the G93A transgenic mouse model of amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis.
Amyotrophic Lateral Sclerosis
The mitochondrial calcium regulator cyclophilin D is an essential component of oestrogen-mediated neuroprotection in amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
The P66Shc/mitochondrial permeability transition pore pathway determines neurodegeneration.
Anaphylaxis
Dust mite ingestion-associated, exercise-induced anaphylaxis: a case report and literature review.
Anemia
A COMPARISON OF RAPID DIAGNOSTIC TESTING (BY PLASMODIUM LACTATE DEHYDROGENASE), AND QUANTITATIVE BUFFY COAT TECHNIQUE IN MALARIA DIAGNOSIS IN CHILDREN.
Anemia
[The activities of the renin-angiotensin-aldosterone and sympathetic-adrenal systems during hemodialysis]
Anemia, Hemolytic
Addressing the Challenges to Diagnose Neonatal Hemolytic Anemia's Aetiologies in Low Ressources Countries: A Case Report.
Angioedema
Food as a trigger for abdominal angioedema attacks in patients with hereditary angioedema.
Anhedonia
Sequencing the serotonergic neuron translatome reveals a new role for Fkbp5 in stress.
Anthrax
Expression and purification of the functional ectodomain of human anthrax toxin receptor 2 in Escherichia coli Origami B cells with assistance of bacterial Trigger Factor.
Antiphospholipid Syndrome
Antiphospholipid syndrome during pegylated interferon alpha-2a therapy for chronic hepatitis C.
Antiphospholipid Syndrome
[Recommendations for the Use of Indirect and Direct Anticoagulants for Long-Term Prophylaxis after Venous Thromboembolism].
Aortic Aneurysm
Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms.
Aortic Aneurysm
Rho-associated protein kinase and cyclophilin a are involved in inorganic phosphate-induced calcification signaling in vascular smooth muscle cells.
Aortic Aneurysm, Abdominal
Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients.
Aortic Aneurysm, Abdominal
Decreased tissue levels of cyclophilin A, a cyclosporine a target and phospho-ERK1/2 in simvastatin patients with abdominal aortic aneurysm.
Aortic Aneurysm, Abdominal
Peptidyl-prolyl isomerase Pin1 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation in ApoE
Aortic Aneurysm, Thoracic
Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients.
Aortic Rupture
A substrate preference for the rough endoplasmic reticulum resident protein FKBP22 during collagen biosynthesis.
Aortic Rupture
The novel missense mutation Met48Lys in FKBP22 changes its structure and functions.
Arrhythmias, Cardiac
Involvement of mitochondrial permeability transition pore (mPTP) in cardiac arrhythmias: Evidence from cyclophilin D knockout mice.
Arrhythmias, Cardiac
Susceptibility to Ventricular Arrhythmias Resulting from Mutations in FKBP1B, PXDNL, and SCN9A Evaluated in hiPSC Cardiomyocytes.
Arrhythmias, Cardiac
Three-dimensional localization of serine 2808, a phosphorylation site in cardiac ryanodine receptor.
Arrhythmias, Cardiac
[From provocation tests to clinical practice: invasive and non-invasive electrophysiology]
Arteriovenous Fistula
Neuroimaging of Takayasu Arteritis in a Patient with Ulcerative Rectocolitis.
Arteritis
Adaptive Mutations in Replicase Transmembrane Subunits Can Counteract Inhibition of Equine Arteritis Virus RNA Synthesis by Cyclophilin Inhibitors.
Arteritis
Cyclophilin inhibitors block arterivirus replication by interfering with viral RNA synthesis.
Arthritis
Cyclophilin A Aggravates Collagen-Induced Arthritis via Promoting Classically Activated Macrophages.
Arthritis
High binding capacity of cyclophilin B to chondrocyte heparan sulfate proteoglycans and its release from the cell surface by matrix metalloproteinases: possible role as a proinflammatory mediator in arthritis.
Arthritis, Experimental
Cyclophilin A Aggravates Collagen-Induced Arthritis via Promoting Classically Activated Macrophages.
Arthritis, Experimental
Cyclophilin A secreted from fibroblast-like synoviocytes is involved in the induction of CD147 expression in macrophages of mice with collagen-induced arthritis.
Arthritis, Rheumatoid
Contribution of Cyclophilin A to the Regulation of Inflammatory Processes in Rheumatoid Arthritis.
Arthritis, Rheumatoid
Cyclophilin A may contribute to the inflammatory processes in rheumatoid arthritis through induction of matrix degrading enzymes and inflammatory cytokines from macrophages.
Arthritis, Rheumatoid
Cyclophilin A up-regulates MMP-9 expression and adhesion of monocytes/macrophages via CD147 signalling pathway in rheumatoid arthritis.
Arthritis, Rheumatoid
Enhanced expression of mRNA for FK506-binding protein 5 in bone marrow CD34 positive cells in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
FK506-Binding Protein 13 Expression Is Upregulated in Interstitial Lung Disease and Correlated with Clinical Severity. A Potentially Protective Role.
Arthritis, Rheumatoid
Inhibition of synovitis and joint destruction by a new single domain antibody specific for cyclophilin A in two different mouse models of rheumatoid arthritis.
Arthritis, Rheumatoid
Possible involvement of peptidylprolyl isomerase Pin1 in rheumatoid arthritis.
Arthritis, Rheumatoid
Presence of cyclophilin A in synovial fluids of patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Vascular-derived reactive oxygen species for homeostasis and diseases.
Arthritis, Rheumatoid
[Expression and significance of cyclophilin A in synovial fibroblasts from patients with rheumatoid arthritis].
Arthrogryposis
Kuskokwim Syndrome, a Recessive Congenital Contracture Disorder, Extends the Phenotype of FKBP10? Mutations.
Asthma
Association of eosinophilic inflammation with FKBP51 expression in sputum cells in asthma.
Asthma
Blocking Cyclophilins in Chronic Phase of Asthma Reduces Leukocyte Persistence and Disease Reactivation.
Asthma
Cyclophilin A Plays Potential Roles in a Rat Model of Asthma and Suppression of Immune Response.
Asthma
Effects of allergen and trigger factor avoidance advice in primary care on asthma control: a randomized-controlled trial.
Asthma
Exercise but not mannitol provocation increases urinary Clara cell protein (CC16) in elite swimmers.
Asthma
Extracellular cyclophilin levels associate with parameters of asthma in phenotypic clusters.
Asthma
Increased FKBP51 in induced sputum cells of chronic obstructive pulmonary disease patients after therapy.
Asthma
Mechanisms of Heightened Airway Sensitivity and Responses to Inhaled SO2 in Asthmatics.
Asthma
Prevalence of bronchial asthma in patients with endoscopically-documented esophagitis.
Asthma
The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation.
Asthma
[Analysis of IgE reactivities of purified allergens from Candida albicans and Malassezia furfur among patients with atopic dermatitis]
Asthma
[Environmental control for allergic diseases--avoiding and killing effect on housedust-mite by eastern red cedar]
Ataxia
Nerve growth factor stimulates interaction of Cayman ataxia protein BNIP-H/Caytaxin with peptidyl-prolyl isomerase Pin1 in differentiating neurons.
Ataxia Telangiectasia
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1.
Atherosclerosis
A fibre cocktail of fenugreek, guar gum and wheat bran reduces oxidative modification of LDL induced by an atherogenic diet in rats.
Atherosclerosis
A search for cyclophilin-A gene (PPIA) variation and its contribution to the risk of atherosclerosis and myocardial infarction.
Atherosclerosis
Association of cyclophilin A level and pulse pressure in predicting recurrence of cerebral infarction.
Atherosclerosis
Bark of Passiflora edulis Treatment Stimulates Antioxidant Capacity, and Reduces Dyslipidemia and Body Fat in db/db Mice.
Atherosclerosis
CD137-CD137L interaction regulates atherosclerosis via cyclophilin A in apolipoprotein E-deficient mice.
Atherosclerosis
Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus.
Atherosclerosis
Cyclophilin A induces macrophage apoptosis and enhances atherosclerotic lesions in high-fat diet-fed hyperglycemic rabbits.
Atherosclerosis
Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice.
Atherosclerosis
Cyclophilin A Protects Cardiomyocytes against Hypoxia/Reoxygenation-Induced Apoptosis via the AKT/Nox2 Pathway.
Atherosclerosis
Cyclophilin A: A Predictive Biomarker of Carotid Stenosis in Cerebral Ischemic Stroke.
Atherosclerosis
Cyclophilin-A: a potential screening marker for vascular disease in type-2 diabetes.
Atherosclerosis
Effects of OX40-OX40 ligand interaction on the levels of ROS and Cyclophilin A in C57BL/6J mice atherogenesis.
Atherosclerosis
Endothelial and vascular smooth muscle cell dysfunction mediated by cyclophylin A and the atheroprotective effects of melatonin.
Atherosclerosis
Expression of REG? in atherosclerotic plaques and promotes endothelial cells apoptosis via the cyclophilin A pathway indicates functional implications in atherogenesis.
Atherosclerosis
Metformin attenuates effects of cyclophilin A on macrophages, reduces lipid uptake and secretion of cytokines by repressing decreased AMPK activity.
Atherosclerosis
Oxidized low-density lipoprotein inhibits the degradation of cyclophilin A via the lysosome in vascular smooth muscle cells.
Atherosclerosis
Oxidized Low-Density Lipoprotein-Induced Cyclophilin A Secretion Requires ROCK-Dependent Diphosphorylation of Myosin Light Chain.
Atherosclerosis
Platelet activation as a trigger factor for inflammation and atherosclerosis.
Atherosclerosis
Proteomic profiling of high glucose primed monocytes identifies cyclophilin A as a potential secretory marker of inflammation in type 2 diabetes.
Atherosclerosis
Rho-associated protein kinase and cyclophilin a are involved in inorganic phosphate-induced calcification signaling in vascular smooth muscle cells.
Atrial Fibrillation
Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12.
Atrial Fibrillation
[Clinical characteristics of patients diagnosed of chronic heart failure attended in Primary Care. The CARDIOPRES study]
Autoimmune Diseases
Autoantibodies to FK506 binding protein 12 (FKBP12) in autoimmune diseases.
Autoimmune Diseases
[Role of mycoplasma pneumoniae infection in aetiopathogenesis of juvenile idiopatic arthritis]
Azoospermia
Alterations in the steroid hormone receptor co-chaperone FKBPL are associated with male infertility: a case-control study.
Bacteriuria
Transcriptional profiles in urine during acute rejection, bacteriuria, CMV infection and stable graft function after renal transplantation.
Biliary Atresia
Targeting extracellular cyclophilins ameliorates disease progression in experimental biliary atresia.
Brachydactyly
Mutations in the Spliceosome Component CWC27 Cause Retinal Degeneration with or without Additional Developmental Anomalies.
Brain Concussion
Knockout of Cyclophilin-D Provides Partial Amelioration of Intrinsic and Synaptic Properties Altered by Mild Traumatic Brain Injury.
Brain Diseases
Hyperactivity of the hypothalamus-pituitary-adrenal axis in lipopolysaccharide-induced neurodevelopmental model of schizophrenia in rats: Effects of antipsychotic drugs.
Brain Edema
Cyclophilin A/Cluster of Differentiation 147 Interactions Participate in Early Brain Injury After Subarachnoid Hemorrhage in Rats.
Brain Injuries
Acutely increased cyclophilin a expression after brain injury: a role in blood-brain barrier function and tissue preservation.
Brain Injuries
Cyclophilin A/Cluster of Differentiation 147 Interactions Participate in Early Brain Injury After Subarachnoid Hemorrhage in Rats.
Brain Injuries
Cyclophilin D-sensitive mitochondrial permeability transition in adult human brain and liver mitochondria.
Brain Injuries
Design, Optimization, and Structural Characterization of an Apoptosis-Inducing Factor Peptide Targeting Human Cyclophilin A to Inhibit Apoptosis Inducing Factor-Mediated Cell Death.
Brain Injuries
Developmental shift of cyclophilin D contribution to hypoxic-ischemic brain injury.
Brain Injuries
Inhibiting the interaction between apoptosis-inducing factor and cyclophilin A prevents brain injury in neonatal mice after hypoxia-ischemia.
Brain Injuries
Search for novel gene markers of traumatic brain injury by time differential microarray analysis.
Brain Injuries
Serum cyclophilin A concentrations and prognosis of acute intracerebral hemorrhage.
Brain Injuries
The 90-day prognostic value of serum cyclophilin A in traumatic brain injury.
Brain Injuries, Traumatic
Anesthesia for euthanasia influences mRNA expression in healthy mice and after traumatic brain injury.
Brain Injuries, Traumatic
Genetic Approach to Elucidate the Role of Cyclophilin D in Traumatic Brain Injury Pathology.
Brain Injuries, Traumatic
The 90-day prognostic value of serum cyclophilin A in traumatic brain injury.
Brain Ischemia
Complex contribution of cyclophilin D to Ca2+-induced permeability transition in brain mitochondria, with relation to the bioenergetic state.
Brain Ischemia
Cyclophilin C-associated protein and cyclophilin C mRNA are upregulated in penumbral neurons and microglia after focal cerebral ischemia.
Brain Ischemia
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia.
Brain Ischemia
Evidence that intracellular cyclophilin A and cyclophilin A/CD147 receptor-mediated ERK1/2 signalling can protect neurons against in vitro oxidative and ischemic injury.
Brain Ischemia
Protection against ischemic brain damage in rats by immunophilin ligand GPI-1046.
Brain Ischemia
The quantification of ADAMTS expression in an animal model of cerebral ischemia using real-time PCR.
Brain Ischemia
The specific FKBP38 inhibitor N-(N',N'-dimethylcarboxamidomethyl)cycloheximide has potent neuroprotective and neurotrophic properties in brain ischemia.
Brain Neoplasms
ALK2 Receptor Kinase Association with FKBP12.6 Is Structurally Conserved with the ALK2-FKBP12 Complex.
Brain Neoplasms
Co-expression network analysis of gene expression profiles of HER2+ breast cancer-associated brain metastasis.
Brain Neoplasms
Tumor-Associated Fibronectin Targeted Liposomal Nanoplatform for Cyclophilin A siRNA Delivery and Targeted Malignant Glioblastoma Therapy.
Breast Neoplasms
12(S)-HETE induces lymph endothelial cell retraction in vitro by upregulation of SOX18.
Breast Neoplasms
Accumulation of cyclophilin A isoforms in conditioned medium of irradiated breast cancer cells.
Breast Neoplasms
Allelic loss of cyclophilin 40, an estrogen receptor-associated immunophilin, in breast carcinomas.
Breast Neoplasms
Autoantibodies to tailor-made panels of tumor-associated antigens in breast carcinoma.
Breast Neoplasms
C6 ceramide dramatically enhances docetaxel-induced growth inhibition and apoptosis in cultured breast cancer cells: A mechanism study.
Breast Neoplasms
Co-expression network analysis of gene expression profiles of HER2+ breast cancer-associated brain metastasis.
Breast Neoplasms
Cyclophilin A Function in Mammary Epithelium Impacts Jak2/Stat5 Signaling, Morphogenesis, Differentiation, and Tumorigenesis in the Mammary Gland.
Breast Neoplasms
Cyclophilin A Inhibitor Debio-025 Targets Crk, Reduces Metastasis, and Induces Tumor Immunogenicity in Breast Cancer.
Breast Neoplasms
Cyclophilin B as a co-regulator of prolactin-induced gene expression and function in breast cancer cells.
Breast Neoplasms
Detection of autoantibodies against cyclophilin A and triosephosphate isomerase in sera from breast cancer patients by proteomic analysis.
Breast Neoplasms
Elevated FKBP52 expression indicates a poor outcome in patients with breast cancer.
Breast Neoplasms
Estradiol-regulated expression of the immunophilins cyclophilin 40 and FKBP52 in MCF-7 breast cancer cells.
Breast Neoplasms
Expression of cyclophilin B is associated with malignant progression and regulation of genes implicated in the pathogenesis of breast cancer.
Breast Neoplasms
Expression of the estrogen receptor-associated immunophilins, cyclophilin 40 and FKBP52, in breast cancer.
Breast Neoplasms
Facile synthesis of a fluorescent cyclosporin a analogue to study cyclophilin 40 and cyclophilin 18 ligands.
Breast Neoplasms
FKBP12 is a predictive biomarker for efficacy of anthracycline-based chemotherapy in breast cancer.
Breast Neoplasms
Human cyclophilin 40 is a heat shock protein that exhibits altered intracellular localization following heat shock.
Breast Neoplasms
Identification of a new panel of serum autoantibodies associated with the presence of in situ carcinoma of the breast in younger women.
Breast Neoplasms
Immunosuppressant inhibition of P-glycoprotein function is independent of drug-induced suppression of peptide-prolyl isomerase and calcineurin activity.
Breast Neoplasms
Induction of vascular endothelial growth factor by peptidyl-prolyl isomerase Pin1 in breast cancer cells.
Breast Neoplasms
Melatonin Regulates Breast Cancer Progression by the lnc010561/miR-30/FKBP3 Axis.
Breast Neoplasms
miRNA-192-5p impacts the sensitivity of breast cancer cells to doxorubicin via targeting peptidylprolyl isomerase A.
Breast Neoplasms
Modulation of cyclophilin gene expression by N-4-(hydroxyphenyl)retinamide: association with reactive oxygen species generation and apoptosis.
Breast Neoplasms
Multilocus genotypes spanning estrogen metabolism associated with breast cancer and fibroadenoma.
Breast Neoplasms
Multiparametric duplex real-time nucleic acid sequence-based amplification assay for mRNA profiling.
Breast Neoplasms
Oroxylin A induces dissociation of hexokinase II from the mitochondria and inhibits glycolysis by SIRT3-mediated deacetylation of cyclophilin D in breast carcinoma.
Breast Neoplasms
Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 as a molecular target in breast cancer: a therapeutic perspective of gynecological cancer.
Breast Neoplasms
Peptidyl-prolyl cis/trans isomerase Pin1 regulates withaferin A-mediated cell cycle arrest in human breast cancer cells.
Breast Neoplasms
Prolyl isomerase cyclophilin a regulation of Janus-activated kinase 2 and the progression of human breast cancer.
Breast Neoplasms
Targeting Pin1 by All-Trans Retinoic Acid (ATRA) Overcomes Tamoxifen Resistance in Breast Cancer via Multifactorial Mechanisms.
Breast Neoplasms
The role of calcineurin/NFAT in SFRP2 induced angiogenesis--a rationale for breast cancer treatment with the calcineurin inhibitor tacrolimus.
Breast Neoplasms
Thrombin-cleaved COOH(-) terminal osteopontin peptide binds with cyclophilin C to CD147 in murine breast cancer cells.
Breast Neoplasms, Male
Detection of protein alterations in male breast cancer using two dimensional gel electrophoresis and mass spectrometry: the involvement of several pathways in tumorigenesis.
Brucellosis
Nasal immunization with recombinant Brucella melitensis bp26 and trigger factor with cholera toxin reduces B. melitensis colonization.
Carcinogenesis
Association between PIN1 promoter polymorphisms and risk of nasopharyngeal carcinoma.
Carcinogenesis
Cyclophilin A Function in Mammary Epithelium Impacts Jak2/Stat5 Signaling, Morphogenesis, Differentiation, and Tumorigenesis in the Mammary Gland.
Carcinogenesis
Cyclophilin C-associated protein (CyCAP) knock-out mice spontaneously develop colonic mucosal hyperplasia and exaggerated tumorigenesis after treatment with carcinogen azoxymethane1.
Carcinogenesis
Cyclophilin D counteracts P53-mediated growth arrest and promotes Ras tumorigenesis.
Carcinogenesis
Cyclophilin D, a component of the permeability transition-pore, is an apoptosis repressor.
Carcinogenesis
Effects of cyclophilin A on cell proliferation and gene expressions in human vascular smooth muscle cells and endothelial cells.
Carcinogenesis
Expression of FK506 binding protein 65 (FKBP65) is decreased in epithelial ovarian cancer cells compared to benign tumor cells and to ovarian epithelium.
Carcinogenesis
FKBP51 promotes migration and invasion of papillary thyroid carcinoma through NF-?B-dependent epithelial-to-mesenchymal transition.
Carcinogenesis
Functional polymorphism of PIN1 rs2233679 is associated with the progression of CIN to early cervical cancer in Hunan Chinese.
Carcinogenesis
Immune-associated proteins with potential in vivo anti-tumor activities are upregulated in lung cancer cells treated with umbelliprenin: A proteomic approach.
Carcinogenesis
Induction of vascular endothelial growth factor by peptidyl-prolyl isomerase Pin1 in breast cancer cells.
Carcinogenesis
Inhibition of the Activity of Cyclophilin A Impedes Prolactin Receptor-Mediated Signaling, Mammary Tumorigenesis, and Metastases.
Carcinogenesis
Loss of the Association between Telomere Length and Mitochondrial DNA Copy Number Contribute to Colorectal Carcinogenesis.
Carcinogenesis
Phosphorylation and Stabilization of PIN1 by JNK Promote Intrahepatic Cholangiocarcinoma Growth.
Carcinogenesis
Pin1 is required for ultraviolet A-stimulated cyclooxygenase-2 induction in mouse epidermal cells.
Carcinogenesis
Proteomics-based approach identified differentially expressed proteins with potential roles in endometrial carcinoma.
Carcinogenesis
Role of cyclophilin B in tumorigenesis and cisplatin resistance in hepatocellular carcinoma.
Carcinogenesis
Single Nucleotide Polymorphisms of PIN1 Promoter Region and Cancer Risk: Evidence from a Meta-Analysis.
Carcinogenesis
Structure-Based Design of Novel Benzimidazole Derivatives as Pin1 Inhibitors.
Carcinogenesis
Synthesis and Evaluation of Dibenzothiophene Analogues as Pin1 Inhibitors for Cervical Cancer Therapy.
Carcinogenesis
The association between PIN1 genetic polymorphisms and the risk of chronic hepatitis B and hepatitis B virus-related liver cirrhosis: A case-control study.
Carcinogenesis
The essential role of FKBP38 in regulating phosphatase of regenerating liver 3 (PRL-3) protein stability.
Carcinogenesis
The prolyl isomerase pin1 regulates mRNA levels of genes with short half-lives by targeting specific RNA binding proteins.
Carcinogenesis
Uncorrelated Effect of Interdomain Contact on Pin1 Isomerase Activity Reveals Positive Catalytic Cooperativity.
Carcinoma
Association of increased ligand cyclophilin A and receptor CD147 with hypoxia, angiogenesis, metastasis and prognosis of tongue squamous cell carcinoma.
Carcinoma
Clinical Significance of Cyclophilin A Expression in Esophageal Squamous Cell Carcinoma.
Carcinoma
Comparative analysis of various tumor-associated antigen-specific t-cell responses in patients with hepatocellular carcinoma.
Carcinoma
Cross-Platform Comparison of Computer-assisted Image Analysis Quantification of In Situ mRNA Hybridization in Investigative Pathology.
Carcinoma
Cyclophilin A Enhances Cell Proliferation and Xenografted Tumor Growth of Early Gastric Cancer.
Carcinoma
Cyclophilin A-EMMPRIN interaction induces invasion of head and neck squamous cell carcinoma.
Carcinoma
Cyclophilin D-mediated apoptosis attributes to sorafenib-induced cytotoxicity in clear cell-renal cell carcinoma.
Carcinoma
Effects of altered expression and localization of cyclophilin A on differentiation of p19 embryonic carcinoma cells.
Carcinoma
Expression and prognostic relevance of Cyclophilin A and matrix metalloproteinase 9 in esophageal squamous cell carcinoma.
Carcinoma
Honokiol inhibits hepatoma carcinoma cell migration through downregulated Cyclophilin B expression.
Carcinoma
Identification and Validation of Housekeeping Genes for Gene Expression Analysis of Cancer Stem Cells.
Carcinoma
Identification of cyclophilin A as a potential prognostic factor for clear-cell renal cell carcinoma by comparative proteomic analysis.
Carcinoma
Increased expression of peroxiredoxin 6 and cyclophilin A in squamous cell carcinoma of the tongue.
Carcinoma
Long non-coding RNA RP11-284F21.9 functions as a ceRNA regulating PPWD1 by competitively binding to miR-769-3p in cervical carcinoma.
Carcinoma
Novel combinational treatment of cisplatin with cyclophilin A inhibitors in human heptocellular carcinomas.
Carcinoma
Novel progesterone target genes identified by an improved differential display technique suggest that progestin-induced growth inhibition of breast cancer cells coincides with enhancement of differentiation.
Carcinoma
Peptidyl-prolyl isomerase Pin1-mediated abrogation of APC-?-catenin interaction in squamous cell carcinoma of cervix.
Carcinoma
Significant correlation of peptidyl-prolyl isomerase overexpression in merkel cell carcinoma with overall survival of patients.
Carcinoma
The rotamase Pin1 is up-regulated, hypophosphorylated and required for cell cycle progression in head and neck squamous cell carcinomas.
Carcinoma
[Expression of cyclophilin A in oral squamous cell carcinoma and its effect on cell proliferation and invasion].
Carcinoma, Hepatocellular
A Critical Role of Peptidylprolyl Isomerase A Pseudogene 22/microRNA-197-3p/Peptidylprolyl Isomerase A Axis in Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
CD147 stimulates hepatoma cells escaping from immune surveillance of T cells by interaction with Cyclophilin A.
Carcinoma, Hepatocellular
Cyclophilin A as a New Therapeutic Target for Hepatitis C Virus-induced Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Cyclophilin A Is Overexpressed in Hepatocellular Carcinoma and Is Associated with the Cell Cycle.
Carcinoma, Hepatocellular
Cyclophilin A promotes human hepatocellular carcinoma cell metastasis via regulation of MMP3 and MMP9.
Carcinoma, Hepatocellular
Cyclophilin Inhibitor NV556 Reduces Fibrosis and Hepatocellular Carcinoma Development in Mice With Non-Alcoholic Steatohepatitis.
Carcinoma, Hepatocellular
Cyclophilin J is a novel peptidyl-prolyl isomerase and target for repressing the growth of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Discovery of 4,6-bis(benzyloxy)-3-phenylbenzofuran as a novel Pin1 inhibitor to suppress hepatocellular carcinoma via upregulating microRNA biogenesis.
Carcinoma, Hepatocellular
Downregulation of Peptidylprolyl isomerase A promotes cell death and enhances doxorubicin-induced apoptosis in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics.
Carcinoma, Hepatocellular
Expression and significance of Pin1, ?-catenin and cyclin D1 in hepatocellular carcinoma.
Carcinoma, Hepatocellular
HCV NS5A activates the mammalian target of rapamycin (mTOR) pathway contributing to cell survival via disrupting the interaction between FK506-binding protein 38 (FKBP38) and mTOR.
Carcinoma, Hepatocellular
Hepatitis C virus non-structural protein NS5A interacts with FKBP38 and inhibits apoptosis in Huh7 hepatoma cells.
Carcinoma, Hepatocellular
High expression level of peptidylprolyl isomerase A is correlated with poor prognosis of liver hepatocellular carcinoma.
Carcinoma, Hepatocellular
Honokiol inhibits hepatoma carcinoma cell migration through downregulated Cyclophilin B expression.
Carcinoma, Hepatocellular
Inhibitory effect of miR-140-5p on doxorubicin resistance of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Interaction of cyclophilin A with a novel binding protein, SR-25, and characterization of their expression pattern in Chinese hepatocellular carcinoma patients.
Carcinoma, Hepatocellular
miR-874-3p is down-regulated in hepatocellular carcinoma and negatively regulates PIN1 expression.
Carcinoma, Hepatocellular
Novel Cyclophilin Inhibitor Decreases Cell Proliferation and Tumor Growth in Models of Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Peptidyl-Prolyl cis/trans Isomerase NIMA-Interacting 1 as a Therapeutic Target in Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Pin1 impairs microRNA biogenesis by mediating conformation change of XPO5 in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Role of cyclophilin B in tumorigenesis and cisplatin resistance in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Subcellular distribution of inorganic pyrophosphatase activity in various normal and neoplastic cell types.
Carcinoma, Hepatocellular
Ubiquitin-specific protease 4 promotes hepatocellular carcinoma progression via cyclophilin A stabilization and deubiquitination.
Carcinoma, Hepatocellular
Up-regulation of beta-actin, cyclophilin and GAPDH in N1S1 rat hepatoma.
Carcinoma, Merkel Cell
Significant correlation of peptidyl-prolyl isomerase overexpression in merkel cell carcinoma with overall survival of patients.
Carcinoma, Non-Small-Cell Lung
Cross-Platform Comparison of Computer-assisted Image Analysis Quantification of In Situ mRNA Hybridization in Investigative Pathology.
Carcinoma, Non-Small-Cell Lung
Cyclophilin A promotes non-small cell lung cancer metastasis via p38 MAPK.
Carcinoma, Non-Small-Cell Lung
Cyclophilin B promotes cell proliferation, migration, invasion and angiogenesis via regulating the STAT3 pathway in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Cyclophilin function in Cancer; lessons from virus replication.
Carcinoma, Non-Small-Cell Lung
Downregulation of cyclophilin A by siRNA diminishes non-small cell lung cancer cell growth and metastasis via the regulation of matrix metallopeptidase 9.
Carcinoma, Non-Small-Cell Lung
FKBP3 Promotes Proliferation of Non-Small Cell Lung Cancer Cells through Regulating Sp1/HDAC2/p27.
Carcinoma, Non-Small-Cell Lung
Protein expression profiling identifies macrophage migration inhibitory factor and cyclophilin a as potential molecular targets in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
RNA interference-mediated gene silencing of cyclophilin A enhances the radiosensitivity of PAa human lung adenocarcinoma cells in vitro.
Carcinoma, Non-Small-Cell Lung
Selective targeting p53(WT) lung cancer cells harboring homozygous p53 Arg72 by an inhibitor of CypA.
Carcinoma, Non-Small-Cell Lung
Translating biomarkers into clinical practice: prognostic implications of cyclophilin A and macrophage migratory inhibitory factor identified from protein expression profiles in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
[Expression of pin1 mRNA in the circulation of non-small cell lung cancer patients and influence of sequence of vessel ligation]
Carcinoma, Renal Cell
FKBP-12 exhibits an inhibitory activity on calcium oxalate crystal growth in vitro.
Carcinoma, Renal Cell
Identification of cyclophilin A as a potential prognostic factor for clear-cell renal cell carcinoma by comparative proteomic analysis.
Carcinoma, Squamous Cell
Association of increased ligand cyclophilin A and receptor CD147 with hypoxia, angiogenesis, metastasis and prognosis of tongue squamous cell carcinoma.
Carcinoma, Squamous Cell
Comparative analysis of various tumor-associated antigen-specific t-cell responses in patients with hepatocellular carcinoma.
Carcinoma, Squamous Cell
Cyclophilin A-EMMPRIN interaction induces invasion of head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Increased expression of peroxiredoxin 6 and cyclophilin A in squamous cell carcinoma of the tongue.
Carcinoma, Squamous Cell
Peptidyl-prolyl isomerase Pin1-mediated abrogation of APC-?-catenin interaction in squamous cell carcinoma of cervix.
Carcinoma, Squamous Cell
The rotamase Pin1 is up-regulated, hypophosphorylated and required for cell cycle progression in head and neck squamous cell carcinomas.
Cardiomegaly
Cyclophilin A Promotes Cardiac Hypertrophy in Apolipoprotein E-Deficient Mice.
Cardiomegaly
CyPA-CD147-ERK1/2-cyclin D2 signaling pathway is upregulated during rat left ventricular hypertrophy.
Cardiomegaly
Extracellular cyclophilin A induces cardiac hypertrophy via the ERK/p47phox pathway.
Cardiomegaly
FKBP12.6 protects heart from AngII-induced hypertrophy through inhibiting Ca2+ /calmodulin-mediated signalling pathways in vivo and in vitro.
Cardiomegaly
Interaction of FKBP12.6 with the cardiac ryanodine receptor C-terminal domain.
Cardiomyopathies
EMMPRIN and its ligand Cyclophilin A as novel diagnostic markers in inflammatory cardiomyopathy.
Cardiomyopathies
Impaired NF-?B signalling underlies cyclophilin D-mediated mitochondrial permeability transition pore opening in doxorubicin cardiomyopathy.
Cardiomyopathies
Interaction of FKBP12.6 with the cardiac ryanodine receptor C-terminal domain.
Cardiomyopathies
[Clinical characteristics of patients diagnosed of chronic heart failure attended in Primary Care. The CARDIOPRES study]
Cardiomyopathy, Dilated
Absence of viral nucleic acids in early and late dilated cardiomyopathy.
Cardiovascular Diseases
Acetylation of cyclophilin A is required for its secretion and vascular cell activation.
Cardiovascular Diseases
Association of FKBP5 polymorphisms with patient susceptibility to coronary artery disease comorbid with depression.
Cardiovascular Diseases
Cyclophilin A is an important mediator of platelet function by regulating integrin ?IIb?3 bidirectional signalling.
Cardiovascular Diseases
Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients.
Cardiovascular Diseases
Dual roles of vascular-derived reactive oxygen species-With a special reference to hydrogen peroxide and cyclophilin A-
Cardiovascular Diseases
Endothelial-to-Mesenchymal Transition and Inflammation Play Key Roles in Cyclophilin A-Induced Pulmonary Arterial Hypertension.
Cardiovascular Diseases
Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation.
Cardiovascular Diseases
Extracellular Cyclophilin A, Especially Acetylated, Causes Pulmonary Hypertension by Stimulating Endothelial Apoptosis, Redox Stress, and Inflammation.
Cardiovascular Diseases
Rho-associated protein kinase and cyclophilin a are involved in inorganic phosphate-induced calcification signaling in vascular smooth muscle cells.
Cardiovascular Diseases
The clinical implications of increased cyclophilin A levels in patients with acute coronary syndromes.
Cardiovascular Diseases
The Role of Peptidyl Prolyl Isomerases in Aging and Vascular Diseases.
Cardiovascular Diseases
[Lipid peroxidation and the antioxidant system in subjects exposed to the influence of extreme factors]
Carotid Stenosis
Association of cyclophilin A level and pulse pressure in predicting recurrence of cerebral infarction.
Carotid Stenosis
Cyclophilin A: A Predictive Biomarker of Carotid Stenosis in Cerebral Ischemic Stroke.
Celiac Disease
COVID-19 and celiac disease: A pathogenetic hypothesis for a celiac outbreak.
Cellulitis
Eosinophilic infiltrate resembling eosinophilic cellulitis (Wells syndrome) in a patient with mycosis fungoides.
Cerebral Hemorrhage
Serum cyclophilin A concentrations and prognosis of acute intracerebral hemorrhage.
Cerebral Infarction
Association of cyclophilin A level and pulse pressure in predicting recurrence of cerebral infarction.
Chagas Disease
A homolog of cyclophilin D is expressed in Trypanosoma cruzi and is involved in the oxidative stress-damage response.
Chagas Disease
Trypanosoma cruzi macrophage infectivity potentiator has a rotamase core and a highly exposed alpha-helix.
Cholangiocarcinoma
Cyclophilin A enhances cell proliferation and tumor growth of liver fluke-associated cholangiocarcinoma.
Cholangiocarcinoma
Expression of peptidyl-prolyl isomerase PIN1 and its role in the pathogenesis of extrahepatic cholangiocarcinoma.
Cholangiocarcinoma
Possible involvement of cyclophilin a processing in fumagillin- induced suppression of cholangiocarcinoma cell proliferation.
Cholangiocarcinoma
Secreted cyclophilin A mediates G1/S phase transition of cholangiocarcinoma cells via CD147/ERK1/2 pathway.
Cholera
FKBP12 mRNA expression is upregulated by intrinsic CNS neurons regenerating axons into peripheral nerve grafts in the brain.
Cholera
Host Cell Chaperones Hsp70/Hsp90 and Peptidyl-Prolyl Cis/Trans Isomerases Are Required for the Membrane Translocation of Bacterial ADP-Ribosylating Toxins.
Cholera
Nasal immunization with recombinant Brucella melitensis bp26 and trigger factor with cholera toxin reduces B. melitensis colonization.
Cluster Headache
Cluster Headache is Associated With the Alcohol Dehydrogenase 4 (ADH4) Gene.
Coinfection
Identification of cryptic coinfection with Plasmodium falciparum in patients presenting with vivax malaria.
Coinfection
Induction of cyclophilin A by influenza A virus infection facilitates group A Streptococcus coinfection.
Coinfection
Single-polarity recombinant adeno-associated virus 2 vector-mediated transgene expression in vitro and in vivo: mechanism of transduction.
Colitis, Ulcerative
FK506-Binding Protein 5 mRNA Levels in Ileal Mucosa Are Associated with Pouchitis in Patients with Ulcerative Colitis.
Colitis, Ulcerative
Serum Cyclophilin A Correlates with Increased Tissue MMP-9 in Patients with Ulcerative Colitis, but Not with Crohn's Disease.
Colitis, Ulcerative
Ulcerative colitis precipitated by a verocytotoxin-producing Escherichia coli infection.
Colitis-Associated Neoplasms
The role of FKBP51 in the prognosis of ulcerative colitis-associated colorectal cancer.
Colonic Neoplasms
Effect of ganoderic acid D on colon cancer Warburg effect: Role of SIRT3/cyclophilin D.
Colonic Neoplasms
FKBP51 expressed by both normal epithelial cells and adenocarcinoma of colon suppresses proliferation of colorectal adenocarcinoma.
Colonic Neoplasms
Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus.
Colonic Neoplasms
Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells.
Colonic Neoplasms
The mitochondrial permeability transition regulates cytochrome c release for apoptosis during endoplasmic reticulum stress by remodeling the cristae junction.
Colonic Neoplasms
[Preparation and application of mouse monoclonal antibodies against human cyclophilin A (CypA)].
Colorectal Neoplasms
Cyclophilin a knokdown inhibits cell migration and invasion through the suppression of epithelial-mesenchymal transition in colorectal cancer cells.
Colorectal Neoplasms
Cyclophilin B induces chemoresistance by degrading wild-type p53 via interaction with MDM2 in colorectal cancer.
Colorectal Neoplasms
Expression and localization of the immunophilin FKBP51 in colorectal carcinomas and primary metastases, and alterations following oxaliplatin-based chemotherapy.
Colorectal Neoplasms
Expression of FK506 binding protein 65 (FKBP65) is decreased in epithelial ovarian cancer cells compared to benign tumor cells and to ovarian epithelium.
Colorectal Neoplasms
Extent of over-expression of hepatocyte growth factor receptor in colorectal tumours is dependent on the choice of normaliser.
Colorectal Neoplasms
FKBP3 mediates oxaliplatin resistance in colorectal cancer cells by regulating HDAC2 expression.
Common Cold
Genetic deficiency and polymorphisms of cyclophilin A reveal its essential role for Human Coronavirus 229E replication.
Common Variable Immunodeficiency
Age-related changes in BAFF and APRIL profiles and upregulation of BAFF and APRIL expression in patients with primary antibody deficiency.
Common Variable Immunodeficiency
Common variable immunodeficiency: two mutations are better than one.
Common Variable Immunodeficiency
Deficiency in TNFRSF13B (TACI) expands T-follicular helper and germinal center B cells via increased ICOS-ligand expression but impairs plasma cell survival.
Common Variable Immunodeficiency
Differential induction of plasma cells by isoforms of human TACI.
Common Variable Immunodeficiency
Functional analysis of transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) mutations associated with common variable immunodeficiency.
Common Variable Immunodeficiency
Genetics of common variable immunodeficiency: role of transmembrane activator and calcium modulator and cyclophilin ligand interactor.
Common Variable Immunodeficiency
Rare mutations in TNFRSF13B increase the risk of asthma symptoms in Swedish children.
Common Variable Immunodeficiency
TACI deficiency enhances antibody avidity and clearance of an intestinal pathogen.
Common Variable Immunodeficiency
TACI mutation with invasive polyclonal CD8+ T-cell lymphoproliferation in a patient with common variable immunodeficiency.
Common Variable Immunodeficiency
TACI mutations and impaired B-cell function in subjects with CVID and healthy heterozygotes.
Common Variable Immunodeficiency
The C104R mutant impairs the function of transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) through haploinsufficiency.
Common Variable Immunodeficiency
The C76R transmembrane activator and calcium modulator cyclophilin ligand interactor mutation disrupts antibody production and B-cell homeostasis in heterozygous and homozygous mice.
Common Variable Immunodeficiency
The murine equivalent of the A181E TACI mutation associated with common variable immunodeficiency severely impairs B-cell function.
Common Variable Immunodeficiency
Transmembrane activator and calcium modulator and cyclophilin ligand interactor enhances CD40-driven plasma cell differentiation.
Common Variable Immunodeficiency
Transmembrane activator and calcium-modulating cyclophilin ligand interactor mutations in common variable immunodeficiency: clinical and immunologic outcomes in heterozygotes.
Common Variable Immunodeficiency
Transmembrane activator and calcium-modulator and cyclophilin ligand interactor mutations in common variable immunodeficiency.
Congenital Abnormalities
Homozygous sequence variants in the FKBP10 gene underlie osteogenesis imperfecta in consanguineous families.
Congenital Abnormalities
Localized chondro-ossification underlies joint dysfunction and motor deficits in the Fkbp10 mouse model of osteogenesis imperfecta.
Congenital Abnormalities
Long-Term Follow-Up Outcomes of 19 Patients with Osteogenesis Imperfecta Type XI and Bruck Syndrome Type I Caused by FKBP10 Variants.
Contracture
A novel homozygous 5bp deletion in FKBP10 causes clinically Bruck syndrome in an Indonesian patient.
Contracture
Bruck syndrome - a rare syndrome of bone fragility and joint contracture and novel homozygous FKBP10 mutation.
Contracture
Kuskokwim Syndrome, a Recessive Congenital Contracture Disorder, Extends the Phenotype of FKBP10? Mutations.
Contracture
Mutations in FKBP10 can cause a severe form of isolated Osteogenesis imperfecta.
Contracture
Mutations in FKBP10 cause recessive osteogenesis imperfecta and type 1 bruck syndrome.
Contracture
Mutations in FKBP10, which result in Bruck syndrome and recessive forms of osteogenesis imperfecta, inhibit the hydroxylation of telopeptide lysines in bone collagen.
Contracture
Mutations in PLOD2 cause autosomal-recessive connective tissue disorders within the Bruck syndrome-Osteogenesis imperfecta phenotypic spectrum.
Contracture
Novel mutations in FKBP10 in Chinese patients with osteogenesis imperfecta and their treatment with zoledronic acid.
Coronary Artery Disease
Crosstalk between cyclophilins and T lymphocytes in coronary artery disease.
Coronary Artery Disease
Cyclophilin A and matrix metalloproteinase-9: Their relationship, association with, and diagnostic relevance in stable coronary artery disease.
Coronary Artery Disease
High Serum Cyclophilin C levels as a risk factor marker for Coronary Artery Disease.
Coronary Artery Disease
Plasma cyclophilin A is a novel biomarker for coronary artery disease.
Coronary Artery Disease
Plasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease.
Coronary Artery Disease
Platelet surface expression of cyclophilin A is associated with increased mortality in patients with symptomatic coronary artery disease.
Coronary Artery Disease
Platelet-bound cyclophilin A in patients with stable coronary artery disease and acute myocardial infarction.
Coronary Artery Disease
PPIA rs6850: A > G single-nucleotide polymorphism is associated with raised plasma cyclophilin A levels in patients with coronary artery disease.
Coronary Artery Disease
Prognostic Impacts of Plasma Levels of Cyclophilin A in Patients With Coronary Artery Disease.
Coronary Disease
Helicobacter pylori active infection in patients with acute coronary heart disease.
Coronavirus Infections
Cyclophilin A and CD147: novel therapeutic targets for the treatment of COVID-19.
Coronavirus Infections
Cyclophilin Inhibitors Restrict Middle East Respiratory Syndrome Coronavirus Via Interferon ? In Vitro And In Mice.
Coronavirus Infections
SARS-CoV-2 pandemic : Time to revive the cyclophilin inhibitor alisporivir.
COVID-19
Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface.
COVID-19
How Children Are Protected From COVID-19? A Historical, Clinical, and Pathophysiological Approach to Address COVID-19 Susceptibility.
COVID-19
Inhibition of SARS-CoV-2 Infection by the Cyclophilin Inhibitor Alisporivir (Debio 025).
COVID-19
Pediatric Obesity-A Potential Risk Factor for Systemic Inflammatory Syndrome Associated to COVID-19, a Case Report.
Craniocerebral Trauma
Levels of S100 calcium binding protein B (S100B), neuron-specific enolase (NSE), and cyclophilin A (CypA) in the serum of patients with severe craniocerebral injury and multiple injuries combined with delirium transferred from the ICU and their prognostic value.
Craniocerebral Trauma
The 90-day prognostic value of serum cyclophilin A in traumatic brain injury.
Craniofacial Abnormalities
Mutations in the Spliceosome Component CWC27 Cause Retinal Degeneration with or without Additional Developmental Anomalies.
Crohn Disease
Acute Intermittent Porphyria - an Unexpected Association in a Patient with Newly Diagnosed Crohn's Disease.
Crohn Disease
Serum Cyclophilin A Correlates with Increased Tissue MMP-9 in Patients with Ulcerative Colitis, but Not with Crohn's Disease.
Cross Infection
Structure of inorganic pyrophosphatase from Staphylococcus aureus reveals conformational flexibility of the active site.
Cystic Fibrosis
FK506 binding protein 8 peptidylprolyl isomerase activity manages a late stage of cystic fibrosis transmembrane conductance regulator (CFTR) folding and stability.
Cystic Fibrosis
FKBP38 peptidylprolyl isomerase promotes the folding of cystic fibrosis transmembrane conductance regulator in the endoplasmic reticulum.
Cysts
The shut-down gene of Drosophila melanogaster encodes a novel FK506-binding protein essential for the formation of germline cysts during oogenesis.
Cytomegalovirus Infections
Cyclophilin A as a target in the treatment of cytomegalovirus infections.
Dacryocystitis
A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjögren's syndrome.
Deafness
Conditional deletion of calcium-modulating cyclophilin ligand causes deafness in mice.
Dehydration
Acute Kidney Injury and Special Considerations during Renal Replacement Therapy in Children with Coronavirus Disease-19: Perspective from the Critical Care Nephrology Section of the European Society of Paediatric and Neonatal Intensive Care.
Dehydration
Selection of Reference Genes for qRT-PCR Analysis in Medicinal Plant Glycyrrhiza under Abiotic Stresses and Hormonal Treatments.
Delirium
Levels of S100 calcium binding protein B (S100B), neuron-specific enolase (NSE), and cyclophilin A (CypA) in the serum of patients with severe craniocerebral injury and multiple injuries combined with delirium transferred from the ICU and their prognostic value.
Dementia
From steroid hormones to depressive states and senile dementias: New mechanistic, therapeutical and predictive approaches.
Dengue
Quantitative proteomic analysis of the Anopheles gambiae (Diptera: Culicidae) midgut infected with o'nyong-nyong virus.
Dental Caries
Trigger factor in Streptococcus mutans is involved in stress tolerance, competence development, and biofilm formation.
Dental Plaque
Concentration dependence of quaternary ammonium monomer on the design of high-performance bioactive composite for root caries restorations.
Dermatitis
Lack of effect of the abnormal fatty acid metabolism in NC/Nga mice on their atopic dermatitis.
Dermatitis, Atopic
Alpha-toxin is produced by skin colonizing Staphylococcus aureus and induces a T helper type 1 response in atopic dermatitis.
Dermatitis, Atopic
Cell-penetrating peptides as antifungals towards Malassezia sympodialis.
Dermatitis, Atopic
Colonization with Staphylococcus aureus in patients with hand eczema: Prevalence and association with severity, atopic dermatitis, subtype and nasal colonization.
Dermatitis, Atopic
Dysregulation of CD36 upon TLR-2 stimulation in monocytes from patients with atopic dermatitis and the TLR2 R753Q polymorphism.
Dermatitis, Atopic
Effect of staphylococcal enterotoxin B on specific antibody production in children with atopic dermatitis.
Dermatitis, Atopic
Higher pH level, corresponding to that on the skin of patients with atopic eczema, stimulates the release of Malassezia sympodialis allergens.
Dermatitis, Atopic
IgE antibodies to Malassezia furfur, M. sympodialis and Pityrosporum orbiculare in patients with atopic dermatitis, seborrheic eczema or pityriasis versicolor, and identification of respective allergens.
Dermatitis, Atopic
IL-18 skews the invariant NKT-cell population via autoreactive activation in atopic eczema.
Dermatitis, Atopic
Isolation of alpha-toxin-producing Staphylococcus aureus from the skin of highly sensitized adult patients with severe atopic dermatitis.
Dermatitis, Atopic
Positive atopy patch test reactions to Pityrosporum orbiculare in atopic dermatitis patients.
Dermatitis, Atopic
Severe atopic dermatitis is associated with sensitization to staphylococcal enterotoxin B (SEB).
Dermatitis, Atopic
Staphylococcal exotoxins exert proinflammatory effects through inhibition of eosinophil apoptosis, increased surface antigen expression (CD11b, CD45, CD54, and CD69), and enhanced cytokine-activated oxidative burst, thereby triggering allergic inflammatory reactions.
Dermatitis, Atopic
[Analysis of IgE reactivities of purified allergens from Candida albicans and Malassezia furfur among patients with atopic dermatitis]
Diabetes Mellitus
Association of serum calcium and heart failure with preserved ejection fraction in patients with type 2 diabetes.
Diabetes Mellitus
Bark of Passiflora edulis Treatment Stimulates Antioxidant Capacity, and Reduces Dyslipidemia and Body Fat in db/db Mice.
Diabetes Mellitus
Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus.
Diabetes Mellitus
Elevated Serum Cyclophilin D Level is Associated with Nonalcoholic Fatty Liver Disease and Higher Fibrosis Scores in Patients with Diabetes Mellitus.
Diabetes Mellitus
Increased frequency of HCV but not HBV infection in type 2 diabetic patients in Turkey.
Diabetes Mellitus
Plasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease.
Diabetes Mellitus
Urinary Cyclophilin A and serum Cystatin C as biomarkers for diabetic nephropathy in children with type 1 diabetes.
Diabetes Mellitus
Urinary Cyclophilin A as a New Marker for Diabetic Nephropathy: A Cross-Sectional Analysis of Diabetes Mellitus.
Diabetes Mellitus, Type 1
Urinary Cyclophilin A and serum Cystatin C as biomarkers for diabetic nephropathy in children with type 1 diabetes.
Diabetes Mellitus, Type 2
Association of serum calcium and heart failure with preserved ejection fraction in patients with type 2 diabetes.
Diabetes Mellitus, Type 2
Cyclophilin A and CD147 associate with progression of diabetic nephropathy.
Diabetes Mellitus, Type 2
FKBP5 expression in human adipose tissue: potential role in glucose and lipid metabolism, adipogenesis and type 2 diabetes.
Diabetes Mellitus, Type 2
Increased frequency of HCV but not HBV infection in type 2 diabetic patients in Turkey.
Diabetes Mellitus, Type 2
Mechanisms of oleic acid deterioration in insulin secretion: role in the pathogenesis of type 2 diabetes.
Diabetes Mellitus, Type 2
Plasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease.
Diabetes Mellitus, Type 2
PPIA rs6850: A > G single-nucleotide polymorphism is associated with raised plasma cyclophilin A levels in patients with coronary artery disease.
Diabetes Mellitus, Type 2
Proteomic profiling of high glucose primed monocytes identifies cyclophilin A as a potential secretory marker of inflammation in type 2 diabetes.
Diabetic Angiopathies
Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus.
Diabetic Angiopathies
[SMOKING AS A TRIGGER FACTOR IN THE DEVELOPMENT OF DIABETIC ANGIOPATHY OF LOWER EXTREMITIES IN MEN WITH METHYLENETETRAHYDROFOLATEREDUCTASE 677TT GENOTYPE].
Diabetic Nephropathies
CIDEC silencing attenuates diabetic nephropathy via inhibiting apoptosis and promoting autophagy.
Diabetic Nephropathies
Cyclophilin A (CyPA) as a Novel Biomarker for Early Detection of Diabetic Nephropathy in an Animal Model.
Diabetic Nephropathies
Cyclophilin A and CD147 associate with progression of diabetic nephropathy.
Diabetic Nephropathies
Delineating a role for the mitochondrial permeability transition pore in diabetic kidney disease by targeting cyclophilin D.
Diabetic Nephropathies
Novel findings of secreted cyclophilin A in diabetic nephropathy and its association with renal protection of dipeptidyl peptidase 4 inhibitor.
Diabetic Nephropathies
Urinary Cyclophilin A and serum Cystatin C as biomarkers for diabetic nephropathy in children with type 1 diabetes.
Diabetic Nephropathies
Urinary Cyclophilin A as a New Marker for Diabetic Nephropathy: A Cross-Sectional Analysis of Diabetes Mellitus.
Diffuse Intrinsic Pontine Glioma
ALK2 Receptor Kinase Association with FKBP12.6 Is Structurally Conserved with the ALK2-FKBP12 Complex.
DiGeorge Syndrome
Bruck syndrome 2 variant lacking congenital contractures and involving a novel compound heterozygous PLOD2 mutation.
Diphtheria
Host Cell Chaperones Hsp70/Hsp90 and Peptidyl-Prolyl Cis/Trans Isomerases Are Required for the Membrane Translocation of Bacterial ADP-Ribosylating Toxins.
Diphtheria
The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells.
Dysentery, Bacillary
Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells.
Dyslipidemias
Bark of Passiflora edulis Treatment Stimulates Antioxidant Capacity, and Reduces Dyslipidemia and Body Fat in db/db Mice.
Dyslipidemias
Caveolin-1 Expression Ameliorates Nephrotic Damage in a Rabbit Model of Cholesterol-Induced Hypercholesterolemia.
Dyspnea
FK506-Binding Protein 13 Expression Is Upregulated in Interstitial Lung Disease and Correlated with Clinical Severity. A Potentially Protective Role.
Echinococcosis
Immunological characterization of Echinococcus granulosus cyclophilin, an allergen reactive with IgE and IgG4 from patients with cystic echinococcosis.
Eczema
Colonization with Staphylococcus aureus in patients with hand eczema: Prevalence and association with severity, atopic dermatitis, subtype and nasal colonization.
Eczema
Eczematous reactions to food in atopic eczema: position paper of the EAACI and GA2LEN.
Eczema
[Environmental control for allergic diseases--avoiding and killing effect on housedust-mite by eastern red cedar]
Ehlers-Danlos Syndrome
A substrate preference for the rough endoplasmic reticulum resident protein FKBP22 during collagen biosynthesis.
Ehlers-Danlos Syndrome
Ehlers-Danlos syndrome kyphoscoliotic type 2 caused by mutations in the FKBP14 gene: an analysis of five cases.
Ehlers-Danlos Syndrome
Osteogenesis imperfecta: Novel genetic variants and clinical observations from a clinical exome study of 54 Indian patients.
Ehlers-Danlos Syndrome
The novel missense mutation Met48Lys in FKBP22 changes its structure and functions.
Embolic Stroke
Calcineurin inhibitors FK506 and SDZ ASM 981 alleviate the outcome of focal cerebral ischemic/reperfusion injury.
Encephalitis
GABA-B Receptor Encephalitis Triggered by Enterovirus Encephalitis in a Patient With Small Cell Lung Cancer: A Case Report.
Encephalitis
Treating refractory post-herpetic anti-N-methyl-d-aspartate receptor encephalitis with rituximab.
Encephalitis, Japanese
Involvement of cyclophilin B in the replication of Japanese encephalitis virus.
Encephalomyelitis
Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis.
Encephalomyelitis
The P66Shc/mitochondrial permeability transition pore pathway determines neurodegeneration.
Encephalomyelitis
The therapeutic effects of the peptidyl-prolyl cis/trans isomerase Pin1 inhibitor juglone on animal-model experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis.
Encephalomyelitis, Autoimmune, Experimental
Cyclophilin inhibitor NIM811 ameliorates experimental allergic encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
The contribution of cyclophilin A to immune-mediated central nervous system inflammation.
Encephalomyelitis, Autoimmune, Experimental
The P66Shc/mitochondrial permeability transition pore pathway determines neurodegeneration.
Encephalomyelitis, Autoimmune, Experimental
The therapeutic effects of the peptidyl-prolyl cis/trans isomerase Pin1 inhibitor juglone on animal-model experimental autoimmune encephalomyelitis.
Endometrial Neoplasms
Down-regulation of focal adhesion signaling in response to cyclophilin A knockdown in human endometrial cancer cells, implicated by cDNA microarray analysis.
Endometrial Neoplasms
Knockdown of cyclophilin A reverses paclitaxel resistance in human endometrial cancer cells via suppression of MAPK kinase pathways.
Endometrial Neoplasms
Proteomics identification of cyclophilin a as a potential prognostic factor and therapeutic target in endometrial carcinoma.
Endometrial Neoplasms
Proteomics-based approach identified differentially expressed proteins with potential roles in endometrial carcinoma.
Endometriosis
Progesterone Resistance in Endometriosis Is Modulated by the Altered Expression of MicroRNA-29c and FKBP4.
Endometriosis
The altered distribution of the steroid hormone receptors and the chaperone immunophilin FKBP52 in a baboon model of endometriosis is associated with progesterone resistance during the window of uterine receptivity.
Endometriosis
The Expression of Cyclophilin A in Ovarian Endometrioma: Its Correlation with Recurrence and Vascularity.
Endometriosis
The Influence Mechanism of Abnormal Immunophilin FKBP52 on the Expression Levels of PR-A and PR-B in Endometriosis Based on Endometrial Stromal Cell Model in Vitro.
Endotoxemia
Cyclophilin D-dependent mitochondrial permeability transition amplifies inflammatory reprogramming in endotoxemia.
Endotoxemia
Lack of cyclophilin D protects against the development of acute lung injury in endotoxemia.
Eosinophilia
Association of eosinophilic inflammation with FKBP51 expression in sputum cells in asthma.
Eosinophilia
[Churg-Strauss vasculitis and idiopathic hypereosinophyl syndrome: role of molecular biology in the differential diagnosis of hypereosinophyl syndrome]
Eosinophilic Esophagitis
Glucocorticoid-regulated genes in eosinophilic esophagitis: a role for FKBP51.
Epidermolysis Bullosa Simplex
Long-Term Follow-Up Outcomes of 19 Patients with Osteogenesis Imperfecta Type XI and Bruck Syndrome Type I Caused by FKBP10 Variants.
Epilepsy
Isolation and expression profiling of genes upregulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients.
Epilepsy
Reversible cerebral vasoconstriction phenomena following indomethacin administration.
Epilepsy
Uncaria rhynchophylla upregulates the expression of MIF and cyclophilin A in kainic acid-induced epilepsy rats: A proteomic analysis.
Epilepsy
Voltage-Dependent Calcium Channels, Calcium Binding Proteins, and Their Interaction in the Pathological Process of Epilepsy.
Esophageal and Gastric Varices
Portal vein thrombosis after variceal endoscopic sclerotherapy in cirrhotic patients: role of genetic thrombophilia.
Esophageal Squamous Cell Carcinoma
Clinical Significance of Cyclophilin A Expression in Esophageal Squamous Cell Carcinoma.
Esophageal Squamous Cell Carcinoma
Expression and prognostic relevance of Cyclophilin A and matrix metalloproteinase 9 in esophageal squamous cell carcinoma.
Esophagitis
Prevalence of bronchial asthma in patients with endoscopically-documented esophagitis.
Essential Hypertension
Association of EDNRA, but not WNK4 or FKBP1B, polymorphisms with essential hypertension.
Essential Hypertension
Cyclophilin-A: a novel biomarker for untreated male essential hypertension.
Facial Paralysis
Mitochondrial Cyclophilin D as a Potential Therapeutic Target for Ischemia-Induced Facial Palsy in Rats.
Familial Primary Pulmonary Hypertension
Detection of Chlamydia pneumoniae in unexplained pulmonary hypertension.
Fatty Liver
Cyclophilin Inhibitor NV556 Reduces Fibrosis and Hepatocellular Carcinoma Development in Mice With Non-Alcoholic Steatohepatitis.
Fatty Liver
Elevated Serum Cyclophilin D Level is Associated with Nonalcoholic Fatty Liver Disease and Higher Fibrosis Scores in Patients with Diabetes Mellitus.
Fetal Growth Retardation
Expression of 52-kDa FK506-binding protein (FKBP52) in human placenta complicated by preeclampsia and intrauterine growth restriction.
Fibroadenoma
Multilocus genotypes spanning estrogen metabolism associated with breast cancer and fibroadenoma.
Foot-and-Mouth Disease
Foot-and-mouth disease virus nonstructural protein 2B interacts with cyclophilin A, modulating virus replication.
Fournier Gangrene
Experience of 80 cases with Fournier's gangrene and "trauma" as a trigger factor in the etiopathogenesis.
Frontotemporal Dementia
Decrease of the Immunophilin FKBP52 Accumulation in Human Brains of Alzheimer's Disease and FTDP-17.
Gastroenteritis
[The development of irritable bowel syndrome after Shigella infection: 3 year follow-up study]
Gastroesophageal Reflux
Prevalence of bronchial asthma in patients with endoscopically-documented esophagitis.
Gaucher Disease
FKBP10 Depletion Enhances Glucocerebrosidase Proteostasis in Gaucher Disease Fibroblasts.
Genetic Diseases, Inborn
Allele frequency of hereditary equine regional dermal asthenia in American Quarter horses in Brazil determined by quantitative real-time PCR with high resolution melting analysis.
Genetic Diseases, Inborn
Effects of FKBP12 and type II BMP receptors on signal transduction by ALK2 activating mutations associated with genetic disorders.
Gingival Overgrowth
Serum cyclophilin A concentrations in renal transplant recipients receiving cyclosporine A: clinical implications for gingival overgrowth.
Glaucoma
FK506-binding protein 51 regulates nuclear transport of the glucocorticoid receptor beta and glucocorticoid responsiveness.
Glaucoma, Open-Angle
Mitochondrial defects and dysfunction in calcium regulation in glaucomatous trabecular meshwork cells.
Glioblastoma
AmotL2, IQGAP1, and FKBP51 Scaffold Proteins in Glioblastoma Stem Cell Niches.
Glioblastoma
Cyclophilin B supports Myc and mutant p53-dependent survival of glioblastoma multiforme cells.
Glioblastoma
Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-kappaB.
Glioblastoma
Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway.
Glioblastoma
Tumor-Associated Fibronectin Targeted Liposomal Nanoplatform for Cyclophilin A siRNA Delivery and Targeted Malignant Glioblastoma Therapy.
Glioma
A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx.
Glioma
ALK2 Receptor Kinase Association with FKBP12.6 Is Structurally Conserved with the ALK2-FKBP12 Complex.
Glioma
Cyclophilin J is a novel peptidyl-prolyl isomerase and target for repressing the growth of hepatocellular carcinoma.
Glioma
Cyclosporin A and sanglifehrin A enhance chemotherapeutic effect of cisplatin in C6 glioma cells.
Glioma
Downregulation of CyclophilinA/CD147 Axis Induces Cell Apoptosis and Inhibits Glioma Aggressiveness.
Glioma
FK506-binding protein 5 inhibits proliferation and stimulates apoptosis of glioma cells.
Glioma
FKBP51 acts as a biomarker of early metastasis and is related to carmustine sensitivity in human glioma cells.
Glioma
FKBP9 promotes the malignant behavior of glioblastoma cells and confers resistance to endoplasmic reticulum stress inducers.
Glioma
Suppression of apoptosis by cyclophilin D via stabilization of hexokinase II mitochondrial binding in cancer cells.
Glioma
Tumor-Associated Fibronectin Targeted Liposomal Nanoplatform for Cyclophilin A siRNA Delivery and Targeted Malignant Glioblastoma Therapy.
Glucose Intolerance
Par14 protein associates with insulin receptor substrate 1 (IRS-1), thereby enhancing insulin-induced IRS-1 phosphorylation and metabolic actions.
Granuloma
Etiologic aspect of sarcoidosis as an allergic endogenous infection caused by Propionibacterium acnes.
Granuloma
Pulmonary granulomas caused experimentally in mice by a recombinant trigger-factor protein of Propionibacterium acnes.
Guillain-Barre Syndrome
Guillain-Barré syndrome after varicella-zoster infection. Report of two cases.
Gynatresia
Perivascular Stem Cell-Derived Cyclophilin A Improves Uterine Environment with Asherman's Syndrome via HIF1?-Dependent Angiogenesis.
Head and Neck Neoplasms
Retromolar trigone--oropharynx junction maligns tumor surgery: transmandibular versus oral approach.
Head and Neck Neoplasms
The rotamase Pin1 is up-regulated, hypophosphorylated and required for cell cycle progression in head and neck squamous cell carcinomas.
Hearing Loss
A substrate preference for the rough endoplasmic reticulum resident protein FKBP22 during collagen biosynthesis.
Hearing Loss
The novel missense mutation Met48Lys in FKBP22 changes its structure and functions.
Heart Arrest
A case of asystole from carotid sinus hypersensitivity during patient positioning for thyroidectomy.
Heart Arrest
Selection of reference genes for quantitative real-time PCR in a rat asphyxial cardiac arrest model.
Heart Diseases
Crystal engineering yields crystals of cyclophilin D diffracting to 1.7 A resolution.
Heart Diseases
Redox sensitivity of the ryanodine receptor interaction with FK506-binding protein.
Heart Failure
Altered stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal Ca(2+) leak through ryanodine receptor in heart failure.
Heart Failure
Association of serum calcium and heart failure with preserved ejection fraction in patients with type 2 diabetes.
Heart Failure
Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure.
Heart Failure
Cyclophilin A predicts clinical outcome in patients with congestive heart failure undergoing endomyocardial biopsy.
Heart Failure
Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice.
Heart Failure
FKBP12 activates the cardiac ryanodine receptor ca-release channel and is antagonised by FKBP12.6.
Heart Failure
Interaction of FKBP12.6 with the cardiac ryanodine receptor C-terminal domain.
Heart Failure
Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure.
Heart Failure
Mitochondrial cyclophilin-D as a potential therapeutic target for post-myocardial infarction heart failure.
Heart Failure
PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle: defective regulation in heart failure.
Heart Failure
Three-dimensional localization of serine 2808, a phosphorylation site in cardiac ryanodine receptor.
Hemangiosarcoma
Expression of FKBP12 in benign and malignant vascular endothelium: an immunohistochemical study on conventional sections and tissue microarrays.
Hematologic Neoplasms
CD147-Cyclophilin a Interactions Promote Proliferation and Survival of Cutaneous T-Cell Lymphoma.
Hematologic Neoplasms
The microtubule-targeting agents, PBOX-6 [pyrrolobenzoxazepine 7-[(dimethylcarbamoyl)oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine] and paclitaxel, induce nucleocytoplasmic redistribution of the peptidyl-prolyl isomerases, cyclophilin A and pin1, in malignant hematopoietic cells.
Hemorrhagic Stroke
Serum cyclophilin A concentrations and prognosis of acute intracerebral hemorrhage.
Hepatitis
[Experimental research of targeting hTERT gene inhibited in hepatocellular carcinoma therapy by RNA interference]
Hepatitis A
Suppression of Viral RNA Binding and the Assembly of Infectious Hepatitis C Virus Particles in vitro by Cyclophilin Inhibitors.
Hepatitis A
The effect of ursodeoxycholic acid in children with prolonged hepatitis A virus infection that may be a trigger factor for autoimmune hepatitis.
Hepatitis B
Alisporivir inhibition of hepatocyte cyclophilins reduces HBV replication and hepatitis B surface antigen production.
Hepatitis B
Characterization of the AhR-hsp90-XAP2 core complex and the role of the immunophilin-related protein XAP2 in AhR stabilization.
Hepatitis B
Hepatic Failure by Spontaneous Reactivation of Hepatitis B Virus without a Trigger Factor in a Patient with Anti-HBs.
Hepatitis B
Hepatitis B virus (HBV) surface antigen interacts with and promotes cyclophilin a secretion: possible link to pathogenesis of HBV infection.
Hepatitis B
Parvulin 14 and parvulin 17 bind to HBx and cccDNA and upregulate HBV replication from cccDNA to virion in a HBx-dependent manner.
Hepatitis B
Proteomic analysis of hepatitis B surface antigen positive transgenic mouse liver and decrease of cyclophilin A.
Hepatitis B, Chronic
Hepatitis B-assocciated adult-onset Still's disease presenting with neutrophilic urticaria.
Hepatitis C
A Conserved Tandem Cyclophilin-Binding Site in Hepatitis C Virus Nonstructural Protein 5A Regulates Alisporivir Susceptibility.
Hepatitis C
A major determinant of cyclophilin dependence and cyclosporine susceptibility of hepatitis C virus identified by a genetic approach.
Hepatitis C
A pharmacokinetic-viral kinetic model describes the effect of alisporivir as monotherapy or in combination with peg-IFN on hepatitis C virologic response.
Hepatitis C
A Proline-Tryptophan Turn in the Intrinsically Disordered Domain 2 of NS5A Protein Is Essential for Hepatitis C Virus RNA Replication.
Hepatitis C
Cellular Growth Kinetics Distinguish a Cyclophilin Inhibitor from an HSP90 Inhibitor as a Selective Inhibitor of Hepatitis C Virus.
Hepatitis C
Chemical genetics approach to hepatitis C virus replication: cyclophilin as a target for anti-hepatitis C virus strategy.
Hepatitis C
Combinations of cyclophilin inhibitor NIM811 with hepatitis C Virus NS3-4A Protease or NS5B polymerase inhibitors enhance antiviral activity and suppress the emergence of resistance.
Hepatitis C
Comparative Study of the Genetic Barriers and Pathways towards Resistance of Selective Inhibitors of Hepatitis C Virus Replication.
Hepatitis C
Correction: essential role of cyclophilin a for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics.
Hepatitis C
Cyclophilin A as a New Therapeutic Target for Hepatitis C Virus-induced Hepatocellular Carcinoma.
Hepatitis C
Cyclophilin A interacts with domain II of hepatitis C virus NS5A and stimulates RNA binding in an isomerase-dependent manner.
Hepatitis C
Cyclophilin A is an essential cofactor for hepatitis C virus infection and the principal mediator of cyclosporine resistance in vitro.
Hepatitis C
Cyclophilin A-independent recruitment of NS5A and NS5B into hepatitis C virus replication complexes.
Hepatitis C
Cyclophilin B escorts the hepatitis C virus RNA polymerase: a viral achilles heel?
Hepatitis C
Cyclophilin B stimulates RNA synthesis by the HCV RNA dependent RNA polymerase.
Hepatitis C
Cyclophilin inhibitors reduce phosphorylation of RNA-dependent protein kinase to restore expression of IFN-stimulated genes in HCV-infected cells.
Hepatitis C
Cyclophilin involvement in the replication of hepatitis C virus and other viruses.
Hepatitis C
Cyclophillin A (CyPA) is required for efficient HCMV DNA replication and reactivation.
Hepatitis C
Cyclosporin A associated helicase-like protein facilitates the association of hepatitis C virus RNA polymerase with its cellular cyclophilin B.
Hepatitis C
Cyclosporine A inhibits hepatitis C virus nonstructural protein 2 through cyclophilin A.
Hepatitis C
DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A.
Hepatitis C
Debio 025, a cyclophilin binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically targeted antiviral therapy for HCV (STAT-C) inhibitors.
Hepatitis C
Differences across cyclophilin A orthologs contribute to the host range restriction of hepatitis C virus.
Hepatitis C
Different mechanisms of hepatitis C virus RNA polymerase activation by cyclophilin A and B in vitro.
Hepatitis C
Discovery of a novel 9-position modified second-generation anti-HCV candidate via bioconversion and semi-synthesis of FR901459.
Hepatitis C
Discovery of ASP5286: A novel non-immunosuppressive cyclophilin inhibitor for the treatment of HCV.
Hepatitis C
Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A.
Hepatitis C
Domain 3 of NS5A protein from the hepatitis C virus has intrinsic alpha-helical propensity and is a substrate of cyclophilin A.
Hepatitis C
Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics.
Hepatitis C
Evaluation of a cyclophilin inhibitor in hepatitis C virus-infected chimeric mice in vivo.
Hepatitis C
Evaluation of Free Energy Calculations for the Prioritization of Macrocycle Synthesis.
Hepatitis C
Exploration of genetically determined resistance against hepatitis C infection in high-risk injecting drug users.
Hepatitis C
Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities.
Hepatitis C
From chemical tools to clinical medicines: nonimmunosuppressive cyclophilin inhibitors derived from the cyclosporin and sanglifehrin scaffolds.
Hepatitis C
Hepatitis C virus non-structural protein NS5A interacts with FKBP38 and inhibits apoptosis in Huh7 hepatoma cells.
Hepatitis C
Hepatitis C Virus NS5A Protein Is a Substrate for the Peptidyl-prolyl cis/trans Isomerase Activity of Cyclophilins A and B.
Hepatitis C
Hepatitis C virus NS5B and host cyclophilin A share a common binding site on NS5A.
Hepatitis C
Identification of cellular and viral factors related to anti-hepatitis C virus activity of cyclophilin inhibitor.
Hepatitis C
Increased cortical expression of FK506 binding protein-51 in HIV-associated neurocognitive disorders.
Hepatitis C
Inhibition of cyclophilins alters lipid trafficking and blocks hepatitis C virus secretion.
Hepatitis C
Inhibition of HCV Replication by Cyclophilin Antagonists Is Linked to Replication Fitness and Occurs by Inhibition of Membranous Web Formation.
Hepatitis C
Interactions of the Disordered Domain II of Hepatitis C Virus NS5A with Cyclophilin A, NS5B, and Viral RNA Show Extensive Overlap.
Hepatitis C
ISGylation of Hepatitis C Virus NS5A Protein Promotes Viral RNA Replication via Recruitment of Cyclophilin A.
Hepatitis C
Mechanism of resistance of hepatitis C virus replicons to structurally distinct cyclophilin inhibitors.
Hepatitis C
Modeling viral kinetics and treatment outcome during alisporivir interferon-free treatment in hepatitis C virus genotype 2 and 3 patients.
Hepatitis C
Multiple cyclophilins involved in different cellular pathways mediate HCV replication.
Hepatitis C
Multiple Mutations in Hepatitis C Virus NS5A Domain II Are Required To Confer a Significant Level of Resistance to Alisporivir.
Hepatitis C
NIM811, a cyclophilin inhibitor, exhibits potent in vitro activity against hepatitis C virus alone or in combination with alpha interferon.
Hepatitis C
Peptidyl-prolyl isomerase pin1 is a cellular factor required for hepatitis C virus propagation.
Hepatitis C
Phenotypic analysis of NS5A variant from liver transplant patient with increased cyclosporine susceptibility.
Hepatitis C
Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.
Hepatitis C
SAR study of bisamides as cyclophilin a inhibitors for the development of host-targeting therapy for hepatitis C virus infection.
Hepatitis C
Structure-Based Discovery of Novel Cyclophilin A Inhibitors for the Treatment of Hepatitis C Virus Infections.
Hepatitis C
Subtype specific differences in NS5A domain II reveals involvement of proline at position 310 in cyclosporine susceptibility of hepatitis C virus.
Hepatitis C
Suppression of Viral RNA Binding and the Assembly of Infectious Hepatitis C Virus Particles in vitro by Cyclophilin Inhibitors.
Hepatitis C
The cyclophilin inhibitor alisporivir prevents hepatitis C virus- mediated mitochondrial dysfunction.
Hepatitis C
The cyclophilin inhibitor Debio 025 combined with PEG IFNalpha2a significantly reduces viral load in treatment-naïve hepatitis C patients.
Hepatitis C
The cyclophilin inhibitor Debio-025 shows potent anti-hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus.
Hepatitis C
The cyclophilin inhibitor SCY-635 disrupts hepatitis C virus NS5A-cyclophilin A complexes.
Hepatitis C
The use of AlphaLISA technology to detect interaction between hepatitis C virus-encoded NS5A and cyclophilin A.
Hepatitis C
Transcriptional machinery of TNF-?-inducible YTH domain containing 2 (YTHDC2) gene.
Hepatitis C, Chronic
An evaluation of the cyclophilin inhibitor Debio 025 and its potential as a treatment for chronic hepatitis C.
Hepatitis C, Chronic
Cyclophilin inhibitors: an emerging class of therapeutics for the treatment of chronic hepatitis C infection.
Hepatitis C, Chronic
The cyclophilin inhibitor Debio 025 combined with PEG IFNalpha2a significantly reduces viral load in treatment-naïve hepatitis C patients.
Hepatitis, Autoimmune
The effect of ursodeoxycholic acid in children with prolonged hepatitis A virus infection that may be a trigger factor for autoimmune hepatitis.
Herpes Simplex
Participation of 3-O-sulfated heparan sulfates in the protection of macrophages by herpes simplex virus-1 glycoprotein D and cyclophilin B against apoptosis.
Herpes Simplex
Treating refractory post-herpetic anti-N-methyl-d-aspartate receptor encephalitis with rituximab.
HIV Infections
Basigin (CD147): a multifunctional transmembrane protein involved in reproduction, neural function, inflammation and tumor invasion.
HIV Infections
Increased cortical expression of FK506 binding protein-51 in HIV-associated neurocognitive disorders.
HIV Infections
SUN2 Silencing Impairs CD4 T Cell Proliferation and Alters Sensitivity to HIV-1 Infection Independently of Cyclophilin A.
Hodgkin Disease
Targeting B-lymphocyte stimulator/B-cell activating factor and a proliferation-inducing ligand in hematologic malignancies.
Hyperalgesia
Silencing of FKBP51 alleviates the mechanical pain threshold, inhibits DRG inflammatory factors and pain mediators through the NF-kappaB signaling pathway.
Hypercholesterolemia
Caveolin-1 Expression Ameliorates Nephrotic Damage in a Rabbit Model of Cholesterol-Induced Hypercholesterolemia.
Hyperglycemia
Novel findings of secreted cyclophilin A in diabetic nephropathy and its association with renal protection of dipeptidyl peptidase 4 inhibitor.
Hyperglycemia
Par14 protein associates with insulin receptor substrate 1 (IRS-1), thereby enhancing insulin-induced IRS-1 phosphorylation and metabolic actions.
Hyperglycemia
Serum concentrations of Cyclophilin A in patients with Nonalcoholic Fatty Liver Disease.
Hyperinsulinism
The housekeeping genes GAPDH and cyclophilin are regulated by metabolic state in the liver of dairy cows.
Hyperkalemia
Acute Ascending Flaccid Paralysis Secondary to Multiple Trigger Factor Induced Hyperkalemia.
Hyperlipidemias
Cyclophilin-A: a novel biomarker for untreated male essential hypertension.
Hyperparathyroidism, Secondary
The peptidyl-prolyl isomerase Pin1 determines parathyroid hormone mRNA levels and stability in rat models of secondary hyperparathyroidism.
Hypersensitivity
Activation of Ca2+ signaling in neutrophils by the mast cell-released immunophilin FKBP12.
Hypersensitivity
C6 ceramide dramatically enhances docetaxel-induced growth inhibition and apoptosis in cultured breast cancer cells: A mechanism study.
Hypersensitivity
Calcineurin-dependent growth of an FK506- and CsA-hypersensitive mutant of Saccharomyces cerevisiae.
Hypersensitivity
Cloning and expression of cyclophilin from Platanus orientalis pollens in Escherichia coli.
Hypersensitivity
Cloning and expression of the cyclophilin Bet v 7, and analysis of immunological cross-reactivity among the cyclophilin A family.
Hypersensitivity
Prevention of Allergic Asthma with Allergen Avoidance Measures and the Role of Exposome.
Hypersensitivity
Pulmonary granulomas caused experimentally in mice by a recombinant trigger-factor protein of Propionibacterium acnes.
Hypersensitivity
Soluble CD14: role in atopic disease and recurrent infections, including otitis media.
Hypersensitivity
The stress regulator FKBP51 drives chronic pain by modulating spinal glucocorticoid signaling.
Hypersensitivity
The Stress Regulator Fkbp51: A Novel and Promising Druggable Target for the Treatment of Persistent Pain States Across Sexes.
Hypersensitivity, Immediate
Activation of Ca2+ signaling in neutrophils by the mast cell-released immunophilin FKBP12.
Hypertension
Bark of Passiflora edulis Treatment Stimulates Antioxidant Capacity, and Reduces Dyslipidemia and Body Fat in db/db Mice.
Hypertension
Cyclophilin A: A Predictive Biomarker of Carotid Stenosis in Cerebral Ischemic Stroke.
Hypertension
Cyclosporin A inhibits flow-mediated activation of endothelial nitric-oxide synthase by altering cholesterol content in caveolae.
Hypertension
Dental caries-related primary hypertension in children and adolescents: Cross-sectional study.
Hypertension
Endothelial-to-Mesenchymal Transition and Inflammation Play Key Roles in Cyclophilin A-Induced Pulmonary Arterial Hypertension.
Hypertension
FK506 binding protein 12 deficiency in endothelial and hematopoietic cells decreases regulatory T cells and causes hypertension.
Hypertension
Influence of pressure overload and ACE inhibitor therapy on constitutive protein mRNA expression in the spontaneously hypertensive rat.
Hypertension
Removal of FKBP12/12.6 from endothelial ryanodine receptors leads to an intracellular calcium leak and endothelial dysfunction.
Hypertension
Renal Deletion of 12 kDa FK506-Binding Protein Attenuates Tacrolimus-Induced Hypertension.
Hypertension
Tacrolimus-induced hypertension: what's endothelial and hematopoietic FKBP12 got to do with it?
Hypertension
The effect of honokiol on pulmonary artery endothelium cell autophagy mediated by cyclophilin A in hypoxic pulmonary arterial hypertension.
Hypertension, Pulmonary
Correction to: Extracellular Cyclophilin A, Especially Acetylated, Causes Pulmonary Hypertension by Stimulating Endothelial Apoptosis, Redox Stress, and Inflammation.
Hypertension, Pulmonary
Cyclophilin A as a biomarker for the therapeutic effect of balloon angioplasty in chronic thromboembolic pulmonary hypertension.
Hypertension, Pulmonary
Endothelial-to-Mesenchymal Transition and Inflammation Play Key Roles in Cyclophilin A-Induced Pulmonary Arterial Hypertension.
Hypertension, Pulmonary
Extracellular Cyclophilin A, Especially Acetylated, Causes Pulmonary Hypertension by Stimulating Endothelial Apoptosis, Redox Stress, and Inflammation.
Hyperthyroidism
Hyperthyroidism as a Potential Trigger for Benign Recurrent Intrahepatic Cholestasis.
Hyperthyroidism
Structural and Functional Features of Ca2+ Transport Systems in Liver Mitochondria of Rats with Experimental Hyperthyroidism.
Hypertrophy, Left Ventricular
Correlations of Serum Cyclophilin A and Melatonin Concentrations with Hypertension-induced Left Ventricular Hypertrophy.
Hyperventilation
Changes in visual-evoked potential habituation induced by hyperventilation in migraine.
Hypoglycemia
Hypoglycemia as a trigger for the syndrome of acute bilateral basal ganglia lesions in uremia.
Hypospadias
Essential role for Co-chaperone Fkbp52 but not Fkbp51 in androgen receptor-mediated signaling and physiology.
Hypospadias
Fkbp52 regulates androgen receptor transactivation activity and male urethra morphogenesis.
Hypospadias
Studies of a co-chaperone of the androgen receptor, FKBP52, as candidate for hypospadias.
Hypoxia-Ischemia, Brain
Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia.
Idiopathic Pulmonary Fibrosis
FK506-Binding Protein 10, a Potential Novel Drug Target for Idiopathic Pulmonary Fibrosis.
Idiopathic Pulmonary Fibrosis
FK506-Binding Protein 13 Expression Is Upregulated in Interstitial Lung Disease and Correlated with Clinical Severity. A Potentially Protective Role.
Immune System Diseases
1-(2,6-Dibenzyloxybenzoyl)-3-(9H-fluoren-9-yl)-urea: A novel cyclophilin A allosteric activator.
Immunologic Deficiency Syndromes
Transmembrane activator and calcium-modulator and cyclophilin ligand interactor mutations in common variable immunodeficiency.
Infarction, Middle Cerebral Artery
Changes in peptidyl-prolyl cis/trans isomerase activity and FK506 binding protein expression following neuroprotection by FK506 in the ischemic rat brain.
Infections
A Critical Role of Cyclophilin A and its Prolyl-Peptidyl Isomerase Activity in the Structure and Function of the HCV Replication Complex.
Infections
A Legionella pneumophila gene encoding a species-specific surface protein potentiates initiation of intracellular infection.
Infections
A Magnaporthe grisea cyclophilin acts as a virulence determinant during plant infection.
Infections
A novel FK-506 binding like protein that lacks peptidyl-prolyl isomerase activity is involved in intracellular infection and in vivo virulence of Burkholderia pseudomallei.
Infections
A Phytophthora capsici RXLR Effector Targets and Inhibits a Plant PPIase to Suppress Endoplasmic Reticulum-Mediated Immunity.
Infections
Adaptive Mutations in Replicase Transmembrane Subunits Can Counteract Inhibition of Equine Arteritis Virus RNA Synthesis by Cyclophilin Inhibitors.
Infections
African swine fever virus infection in Classical swine fever subclinically infected wild boars.
Infections
Alisporivir, a cyclosporin derivative that selectively inhibits cyclophilin, for the treatment of HCV infection.
Infections
Alpha-Defensin HD5 Inhibits Furin Cleavage of Human Papillomavirus 16 L2 To Block Infection.
Infections
Analysis of human cell heterokaryons demonstrates that target cell restriction of cyclosporine-resistant human immunodeficiency virus type 1 mutants is genetically dominant.
Infections
Analysis of reference gene stability after Israeli acute paralysis virus infection in bumblebees Bombus terrestris.
Infections
Antibodies are generated during infection to Coxiella burnetii macrophage infectivity potentiator protein (Cb-Mip).
Infections
Biochemical and functional analyses of the Mip protein: influence of the N-terminal half and of peptidylprolyl isomerase activity on the virulence of Legionella pneumophila.
Infections
CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A.
Infections
CD147/EMMPRIN acts as a functional entry receptor for measles virus on epithelial cells.
Infections
Cellular restriction targeting viral capsids perturbs human immunodeficiency virus type 1 infection of nondividing cells.
Infections
Channel catfish, Ictalurus punctatus, cyclophilin A and B cDNA characterization and expression analysis.
Infections
Characterization of the behavior of functional viral genomes during the early steps of human immunodeficiency virus type 1 infection.
Infections
Chlamydia trachomatis Mip-like protein has peptidyl-prolyl cis/trans isomerase activity that is inhibited by FK506 and rapamycin and is implicated in initiation of chlamydial infection.
Infections
Chlamydial serology: comparative diagnostic value of immunoblotting, microimmunofluorescence test, and immunoassays using different recombinant proteins as antigens.
Infections
Contribution of PDZD8 to Stabilization of the Human Immunodeficiency Virus Type 1 Capsid.
Infections
Critical role of TLR2 in triggering protective immunity with cyclophilin entrapped in oligomannose-coated liposomes against Neospora caninum infection in mice.
Infections
Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid.
Infections
Curing a viral infection by targeting the host: the example of cyclophilin inhibitors.
Infections
Cyclophilin A as a potential genetic adjuvant to improve HIV-1 Gag DNA vaccine immunogenicity by eliciting broad and long-term Gag-specific cellular immunity in mice.
Infections
Cyclophilin A Inhibits Human Respiratory Syncytial Virus (RSV) Replication by Binding to RSV-N through Its PPIase Activity.
Infections
Cyclophilin A inhibits rotavirus replication by facilitating host IFN-I production.
Infections
Cyclophilin A levels dictate infection efficiency of human immunodeficiency virus type 1 capsid escape mutants A92E and G94D.
Infections
Cyclophilin A mediates the ox-LDL-induced activation and apoptosis of macrophages via autophagy.
Infections
Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infection.
Infections
Cyclophilin A-dependent restriction of human immunodeficiency virus type 1 capsid mutants for infection of nondividing cells.
Infections
Cyclophilin A-Dependent Restriction to Capsid N121K Mutant Human Immunodeficiency Virus Type 1 in a Broad Range of Cell Lines.
Infections
Cyclophilin BcCyp2 Regulates Infection-Related Development to Facilitate Virulence of the Gray Mold Fungus Botrytis cinerea.
Infections
Cyclophilin inhibitors reduce phosphorylation of RNA-dependent protein kinase to restore expression of IFN-stimulated genes in HCV-infected cells.
Infections
Cyclophilin Inhibitors Restrict Middle East Respiratory Syndrome Coronavirus Via Interferon ? In Vitro And In Mice.
Infections
Cyclophilin inhibitors: an emerging class of therapeutics for the treatment of chronic hepatitis C infection.
Infections
Cyclophilins Facilitate Dissociation of the Human Papillomavirus Type 16 Capsid Protein L1 from the L2/DNA Complex following Virus Entry.
Infections
Cyclosporine A-resistant human immunodeficiency virus type 1 mutants demonstrate that Gag encodes the functional target of cyclophilin A.
Infections
CYP1, a hypovirus-regulated cyclophilin, is required for virulence in the chestnut blight fungus.
Infections
Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner.
Infections
Decreased of BAFF-R expression and B cells maturation in patients with hepatitis B virus-related hepatocellular carcinoma.
Infections
Detection of high prevalence of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Assosa zone, Ethiopia: implication for malaria diagnosis.
Infections
Effects of gag mutations on human immunodeficiency virus type 1 particle assembly, processing, and cyclophilin A incorporation.
Infections
Effects of hesperidin on the growth performance, antioxidant capacity, immune responses and disease resistance of red swamp crayfish (Procambarus clarkii).
Infections
Efficient transduction of human hematopoietic repopulating cells with a chimeric HIV1-based vector including SIV capsid.
Infections
Escape from the Dominant HLA-B27-Restricted Cytotoxic T-Lymphocyte Response in Gag Is Associated with a Dramatic Reduction in Human Immunodeficiency Virus Type 1 Replication.
Infections
Etiologic aspect of sarcoidosis as an allergic endogenous infection caused by Propionibacterium acnes.
Infections
Evaluation of a rapid test for histidine rich protein 2 for diagnosis of Plasmodium falciparum infection in Cameroonian children.
Infections
Expression of pepper cyclophilin gene is differentially regulated during the pathogen infection and abiotic stress conditions.
Infections
Field performance of malaria rapid diagnostic test for the detection of Plasmodium falciparum infection in Odisha State, India.
Infections
From chemical tools to clinical medicines: nonimmunosuppressive cyclophilin inhibitors derived from the cyclosporin and sanglifehrin scaffolds.
Infections
Functional analysis of the Listeria monocytogenes secretion chaperone PrsA2 and its multiple contributions to bacterial virulence.
Infections
Gene Expression Analysis of a Panel of Cell Lines That Differentially Restrict HIV-1 CA Mutants Infection in a Cyclophilin A-Dependent Manner.
Infections
Generation of a novel human cytomegalovirus bacterial artificial chromosome tailored for transduction of exogenous sequences.
Infections
Genetic polymorphism of histidine rich protein 2 in Plasmodium falciparum isolates from different infection sources in Yunnan Province, China.
Infections
Helicobacter pylori active infection in patients with acute coronary heart disease.
Infections
Hepatitis B virus (HBV) surface antigen interacts with and promotes cyclophilin a secretion: possible link to pathogenesis of HBV infection.
Infections
Hepatitis B-assocciated adult-onset Still's disease presenting with neutrophilic urticaria.
Infections
Hepatocytes that express variants of cyclophilin a are resistant to HCV infection and replication.
Infections
HIV-1 Integrase Binding to its Cellular Partners: A Perspective from Computational Biology.
Infections
Home exposure to Arabian incense (bakhour) and asthma symptoms in children: a community survey in two regions in Oman.
Infections
Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir.
Infections
Human Immunodeficiency Virus Type 1 (HIV-1) Capsid Mutation N74D Alters Cyclophilin A Dependence and Impairs Macrophage Infection.
Infections
Identification of Legionella spp. by 19 European reference laboratories: results of the European Working Group for Legionella Infections External Quality Assessment Scheme using DNA sequencing of the macrophage infectivity potentiator gene and dedicated online tools.
Infections
Immunization of female BALB/c mice with Neospora cyclophilin and/or NcSRS2 elicits specific antibody response and prevents against challenge infection by Neospora caninum.
Infections
Immunization with the Leishmania infantum recombinant cyclophilin protein 1 confers partial protection to subsequent parasite infection and generates specific memory T cells.
Infections
Implication of TRIM alpha and TRIMCyp in interferon-induced anti-retroviral restriction activities.
Infections
Increased frequency of HCV but not HBV infection in type 2 diabetic patients in Turkey.
Infections
Independent genesis of chimeric TRIM5-cyclophilin proteins in two primate species.
Infections
Induction of cyclophilin A by influenza A virus infection facilitates group A Streptococcus coinfection.
Infections
Induction of protective immunity against Chlamydia muridarum intravaginal infection with the chlamydial immunodominant antigen macrophage infectivity potentiator.
Infections
Influences of cyclosporin A and non-immunosuppressive derivatives on cellular cyclophilins and viral nucleocapsid protein during human coronavirus 229E replication.
Infections
Inhibition of Cyclophilin A on the replication of red spotted grouper nervous necrosis virus associates with multiple pro-inflammatory factors.
Infections
Inhibition of HIV-1 infection by a CCR5-binding cyclophilin from Toxoplasma gondii.
Infections
Investigation of reference gene expression during human herpesvirus 6B infection indicates peptidylprolyl isomerase A as a stable reference gene and TATA box binding protein as a gene up-regulated by this virus.
Infections
Keeping your armour intact: how HIV-1 evades detection by the innate immune system: HIV-1 capsid controls detection of reverse transcription products by the cytosolic DNA sensor cGAS.
Infections
KIF5B and Nup358 Cooperatively Mediate the Nuclear Import of HIV-1 during Infection.
Infections
Legionella pneumophila mip gene potentiates intracellular infection of protozoa and human macrophages.
Infections
Legionella pneumophila Mip, a surface-exposed peptidylproline cis-trans-isomerase, promotes the presence of phospholipase C-like activity in culture supernatants.
Infections
Legionella-protozoa-nematode interactions in aquatic biofilms and influence of Mip on Caenorhabditis elegans colonization.
Infections
Lentiviral vector gene transfer is limited by the proteasome at postentry steps in various types of stem cells.
Infections
Malaria diagnosis: false negative parasight-F tests in falciparum malaria patients in Nigeria.
Infections
Mechanism of resistance of hepatitis C virus replicons to structurally distinct cyclophilin inhibitors.
Infections
Microarray Technology May Reveal the Contribution of Allergen Exposure and Rhinovirus Infections as Possible Triggers for Acute Wheezing Attacks in Preschool Children.
Infections
Microscopic polyangiitis following recurrent Staphylococcus aureus bacteremia and infectious endocarditis.
Infections
Molecular analysis of two novel Neisseria gonorrhoeae virulent components: the macrophage infectivity potentiator and the outer membrane protein A.
Infections
Molecular cloning and functional characterization of cyclophilin A in yellow catfish (Pelteobagrus fulvidraco).
Infections
Mortality among children in rural areas of the People's Democratic Republic of Yemen.
Infections
Murine cytomegalovirus inhibits interferon gamma-induced antigen presentation to CD4 T cells by macrophages via regulation of expression of major histocompatibility complex class II-associated genes.
Infections
Mycobacterium tuberculosis cyclophilin A uses novel signal sequence for secretion and mimics eukaryotic cyclophilins for interaction with host protein repertoire.
Infections
Ng-MIP, a surface-exposed lipoprotein of Neisseria gonorrhoeae, has a peptidyl-prolyl cis/trans isomerase (PPIase) activity and is involved in persistence in macrophages.
Infections
Novel activities of cyclophilin A and cyclosporin A during HIV-1 infection of primary lymphocytes and macrophages.
Infections
Novel antigens of Helicobacter pylori correspond to ulcer-related antibody pattern of sera from infected patients.
Infections
Novel Cycloheximide Derivatives Targeting the Moonlighting Protein Mip Exhibit Specific Antimicrobial Activity Against Legionella pneumophila.
Infections
Novel Regulation of Alpha-Toxin and the Phenol-Soluble Modulins by Peptidyl-Prolyl cis/trans Isomerase Enzymes in Staphylococcus aureus.
Infections
Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2.
Infections
Overexpression of a cotton cyclophilin gene (GhCyp1) in transgenic tobacco plants confers dual tolerance to salt stress and Pseudomonas syringae pv. tabaci infection.
Infections
Parvulin 14 and parvulin 17 bind to HBx and cccDNA and upregulate HBV replication from cccDNA to virion in a HBx-dependent manner.
Infections
Peptidyl-prolyl cis-trans isomerases, a superfamily of ubiquitous folding catalysts.
Infections
Peptidyl-Prolyl-cis/trans-Isomerases Mip and PpiB of Legionella pneumophila Contribute to Surface Translocation, Growth at Suboptimal Temperature, and Infection.
Infections
Peste des petits ruminants virus hemagglutinin (H) induces lysosomal degradation of host cyclophilin A to facilitate viral replication.
Infections
Polymorphisms in the regulatory region of the Cyclophilin A gene influence the susceptibility for HIV-1 infection.
Infections
Porcine epidemic diarrhea virus induces caspase-independent apoptosis through activation of mitochondrial apoptosis-inducing factor.
Infections
Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components.
Infections
Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.
Infections
Prevalence and clinical impact of malaria infections detected with a highly sensitive HRP2 rapid diagnostic test in Beninese pregnant women.
Infections
Rapid-onset asthma attack: a prospective cohort study about characteristics and response to emergency department treatment.
Infections
Redistribution of cyclophilin A to viral factories during vaccinia virus infection and its incorporation into mature particles.
Infections
Reliability of rapid diagnostic tests in diagnosing pregnancy-associated malaria in north-eastern Tanzania.
Infections
Requirements for capsid-binding and an effector function in TRIMCyp-mediated restriction of HIV-1.
Infections
Retromolar trigone--oropharynx junction maligns tumor surgery: transmandibular versus oral approach.
Infections
Selection for loss of Ref1 activity in human cells releases human immunodeficiency virus type 1 from cyclophilin A dependence during infection.
Infections
Serum and mucosal cytokine profiles in patients with active Helicobacter pylori and ischemic heart disease: is there a relationship?
Infections
Soluble CD14: role in atopic disease and recurrent infections, including otitis media.
Infections
Spodoptera litura cyclophilin A is required for Microplitis bicoloratus bracovirus-induced apoptosis during insect cellular immune response.
Infections
Structural insights into the stabilization of the human immunodeficiency virus type 1 capsid protein by the cyclophilin-binding domain and implications on the virus cycle.
Infections
Structure-based identification of small molecule compounds targeting cell cyclophilin A with anti-HIV-1 activity.
Infections
SUN2 Silencing Impairs CD4 T Cell Proliferation and Alters Sensitivity to HIV-1 Infection Independently of Cyclophilin A.
Infections
Suppression of Viral RNA Binding and the Assembly of Infectious Hepatitis C Virus Particles in vitro by Cyclophilin Inhibitors.
Infections
Synthesis and evaluation of Glypsi(PO(2)R-N)Pro-containing pseudopeptides as novel inhibitors of the human cyclophilin hCyp-18.
Infections
TACI Contributes to Plasmodium yoelii Host Resistance by Controlling T Follicular Helper Cell Response and Germinal Center Formation.
Infections
TACI deficiency leads to alternatively activated macrophage phenotype and susceptibility to Leishmania infection.
Infections
Targeting cyclophilin-D by miR-1281 protects human macrophages from Mycobacterium tuberculosis-induced programmed necrosis and apoptosis.
Infections
The cyclophilin inhibitor SCY-635 suppresses viral replication and induces endogenous interferons in patients with chronic HCV genotype 1 infection.
Infections
The host proteins transportin SR2/TNPO3 and cyclophilin A exert opposing effects on HIV-1 uncoating.
Infections
The Leishmania donovani chaperone cyclophilin 40 is essential for intracellular infection independent of its stage-specific phosphorylation status.
Infections
The multi-drug efflux system AcrABZ-TolC is essential for infection of Salmonella Typhimurium by the flagellum-dependent bacteriophage Chi.
Infections
The Novel Cyclophilin Inhibitor CPI-431-32 Concurrently Blocks HCV and HIV-1 Infections via a Similar Mechanism of Action.
Infections
The peptidyl-prolyl cis/trans isomerase Pin1 interacts with three early regulatory proteins of human cytomegalovirus.
Infections
The PPIase active site of Legionella pneumophila Mip protein is involved in the infection of eukaryotic host cells.
Infections
The requirement for nucleoporin NUP153 during human immunodeficiency virus type 1 infection is determined by the viral capsid.
Infections
The streptococcal lipoprotein rotamase A (SlrA) is a functional peptidyl-prolyl isomerase involved in pneumococcal colonization.
Infections
Toxoplasma gondii cyclophilin 18 regulates the proliferation and migration of murine macrophages and spleen cells.
Infections
Transcription and Expression of Plasmodium falciparum Histidine-Rich Proteins in Different Stages and Strains: Implications for Rapid Diagnostic Tests.
Infections
Transcriptional profiles in urine during acute rejection, bacteriuria, CMV infection and stable graft function after renal transplantation.
Infections
Transcriptome analysis of the entomopathogenic fungus Beauveria bassiana grown on cuticular extracts of the coffee berry borer (Hypothenemus hampei).
Infections
Trigger factor of Streptococcus suis is involved in stress tolerance and virulence.
Infections
Ulcerative colitis precipitated by a verocytotoxin-producing Escherichia coli infection.
Infections
Vaccination with MIP or Pgp3 induces cross-serovar protection against chlamydial genital tract infection in mice.
Infections
Vital role for cyclophilin B (CypB) in asexual development, dimorphic transition and virulence of Beauveria bassiana.
Infections
[Cloning and expressing of cyclophilin B gene from Schistosoma japonnicum and the analysis of immunoprotective effect]
Infections
[Diagnosis and importance of the opportunistic herpes-virus infection in etiology and pathogenesis of different eye diseases]
Infections
[Macrophage activation syndrome in children with rheumatic disorders: a retrospective study on 6 patients]
Infertility
Clomiphene citrate as a possible cause of a psychotic reaction during infertility treatment.
Infertility
Deficiency of co-chaperone immunophilin FKBP52 compromises sperm fertilizing capacity.
Infertility, Female
Proteomic analysis identifies immunophilin FK506 binding protein 4 (FKBP52) as a downstream target of Hoxa10 in the periimplantation mouse uterus.
Infertility, Male
Alterations in the steroid hormone receptor co-chaperone FKBPL are associated with male infertility: a case-control study.
Inflammatory Bowel Diseases
P046. CD99 and cyclophilin A correlate differently in patients with inflammatory bowel diseases.
Influenza, Human
Chicken cyclophilin A is an inhibitory factor to influenza virus replication.
Influenza, Human
Cyclophilin A interacts with influenza A virus M1 protein and impairs the early stage of the viral replication.
Influenza, Human
Cyclophilin A Restricts Influenza A Virus Replication through Degradation of the M1 Protein.
Influenza, Human
Cyclophilin E functions as a negative regulator to influenza virus replication by impairing the formation of the viral ribonucleoprotein complex.
Influenza, Human
Cyclophillin A (CyPA) is required for efficient HCMV DNA replication and reactivation.
Influenza, Human
Cyclosporin A inhibits the influenza virus replication through cyclophilin A-dependent and -independent pathways.
Influenza, Human
Cyclosporin A inhibits the propagation of influenza virus by interfering with a late event in the virus life cycle.
Influenza, Human
Induction of cyclophilin A by influenza A virus infection facilitates group A Streptococcus coinfection.
Influenza, Human
Insights into the roles of cyclophilin A during influenza virus infection.
Insulin Resistance
CIDEC silencing attenuates diabetic nephropathy via inhibiting apoptosis and promoting autophagy.
Insulin Resistance
Disruption of cyclophilin D-mediated calcium transfer from the ER to mitochondria contributes to hepatic ER stress and insulin resistance.
Insulin Resistance
FKBP5 expression in human adipose tissue: potential role in glucose and lipid metabolism, adipogenesis and type 2 diabetes.
Insulin Resistance
Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Is Required for Insulin Signaling and Is Implicated in Hepatic Insulin Resistance.
Insulin Resistance
Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle.
Intestinal Volvulus
A divergent multi-domain cyclophilin is highly conserved between parasitic and free-living nematode species and is important in larval muscle development.
Intestinal Volvulus
A novel cyclophilin from parasitic and free-living nematodes with a unique substrate- and drug-binding domain.
Intracranial Aneurysm
Cyclophilin A in Ruptured Intracranial Aneurysm: A Prognostic Biomarker.
Ischemic Stroke
Cyclophilin A: A Predictive Biomarker of Carotid Stenosis in Cerebral Ischemic Stroke.
Ischemic Stroke
Interplay between Notch and p53 promotes neuronal cell death in ischemic stroke.
Joint Instability
The novel missense mutation Met48Lys in FKBP22 changes its structure and functions.
Keloid
Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization.
Kidney Diseases
Therapeutic Approaches Targeting Proteostasis in Kidney Disease and Fibrosis.
Legionellosis
Detection of legionellae in hospital water samples by quantitative real-time LightCycler PCR.
Legionnaires' Disease
Pipecolic Acid Derivatives As Small-Molecule Inhibitors of the Legionella MIP Protein.
Legionnaires' Disease
Solution structure of the Legionella pneumophila Mip-rapamycin complex.
Leprosy, Lepromatous
Autoantibodies against cyclophilin in systemic lupus erythematosus and Lyme disease.
Leukemia
A cyclophilin B gene encodes antigenic epitopes recognized by HLA-A24-restricted and tumor-specific CTLs.
Leukemia
High frequency of alternative splicing of human genes participating in the HIV-1 life cycle: a model using TSG101, betaTrCP, PPIA, INI1, NAF1, and PML.
Leukemia
Identification of Chemoresistance-Related Cell-Surface Glycoproteins in Leukemia Cells and Functional Validation of Candidate Glycoproteins.
Leukemia
Identification of several cyclosporine binding proteins in lymphoid and non-lymphoid cells in vivo.
Leukemia
Primary identification, biochemical characterization, and immunologic properties of the allergenic pollen cyclophilin cat R 1.
Leukemia, Lymphocytic, Chronic, B-Cell
FK506 binding proteins as targets in anticancer therapy.
Leukemia, Lymphocytic, Chronic, B-Cell
Targeting B-lymphocyte stimulator/B-cell activating factor and a proliferation-inducing ligand in hematologic malignancies.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
The microtubule-targeting agents, PBOX-6 [pyrrolobenzoxazepine 7-[(dimethylcarbamoyl)oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine] and paclitaxel, induce nucleocytoplasmic redistribution of the peptidyl-prolyl isomerases, cyclophilin A and pin1, in malignant hematopoietic cells.
Leukemia, T-Cell
Identification of several cyclosporine binding proteins in lymphoid and non-lymphoid cells in vivo.
Leukemia, T-Cell
Peptidylproline cis-trans-isomerase Pin1 interacts with human T-cell leukemia virus type 1 tax and modulates its activation of NF-kappaB.
Liver Abscess
Differential gene expression in Entamoeba histolytica isolated from amoebic liver abscess.
Liver Abscess, Amebic
Cloning and characterization of Entamoeba histolytica antigens recognized by human secretory IgA antibodies.
Liver Cirrhosis
A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models.
Liver Cirrhosis
Evaluation of NV556, a Novel Cyclophilin Inhibitor, as a Potential Antifibrotic Compound for Liver Fibrosis.
Liver Cirrhosis
N-methyl-4-isoleucine cyclosporine attenuates CCl? -induced liver fibrosis in rats by interacting with cyclophilin B and D.
Liver Diseases
A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models.
Liver Diseases
Elevated Serum Cyclophilin D Level is Associated with Nonalcoholic Fatty Liver Disease and Higher Fibrosis Scores in Patients with Diabetes Mellitus.
Liver Diseases
Pathogenesis and pathology of liver disease associated with alpha 1-antitrypsin deficiency.
Liver Diseases
Serum concentrations of Cyclophilin A in patients with Nonalcoholic Fatty Liver Disease.
Liver Failure
Hepatic Failure by Spontaneous Reactivation of Hepatitis B Virus without a Trigger Factor in a Patient with Anti-HBs.
Liver Neoplasms
Andrographolide induces autophagic cell death in human liver cancer cells through cyclophilin D-mediated mitochondrial permeability transition pore.
Lung Diseases, Interstitial
FK506-Binding Protein 13 Expression Is Upregulated in Interstitial Lung Disease and Correlated with Clinical Severity. A Potentially Protective Role.
Lung Injury
Developmental regulation and coordinate reexpression of FKBP65 with extracellular matrix proteins after lung injury suggest a specialized function for this endoplasmic reticulum immunophilin.
Lung Injury
Epithelial Cell Death is an Important Contributor to Oxidant-Mediated Acute Lung Injury.
Lung Neoplasms
A complex pattern of translational initiation and phosphorylation in L-myc proteins.
Lung Neoplasms
Cyclophilin A is upregulated in small cell lung cancer and activates ERK1/2 signal.
Lung Neoplasms
Cyclophilin B promotes cell proliferation, migration, invasion and angiogenesis via regulating the STAT3 pathway in non-small cell lung cancer.
Lung Neoplasms
Discovery of novel cyclophilin a ligands using an h/d exchange- and mass spectrometry-based strategy.
Lung Neoplasms
Downregulation of cyclophilin A by siRNA diminishes non-small cell lung cancer cell growth and metastasis via the regulation of matrix metallopeptidase 9.
Lung Neoplasms
FKBP3 Promotes Proliferation of Non-Small Cell Lung Cancer Cells through Regulating Sp1/HDAC2/p27.
Lung Neoplasms
FKBP51 induces p53-dependent apoptosis and enhances drug sensitivity of human non-small-cell lung cancer cells.
Lung Neoplasms
Glucocorticoid receptor activates poised FKBP51 locus through long-distance interactions.
Lung Neoplasms
Identification of suitable reference genes for gene expression studies using quantitative polymerase chain reaction in lung cancer in vitro.
Lung Neoplasms
Inhibition of Plk1 and Pin1 by 5'-nitro-indirubinoxime suppresses human lung cancer cells.
Lung Neoplasms
Phase 1 clinical study of cyclophilin B peptide vaccine for patients with lung cancer.
Lung Neoplasms
Pre-clinical evaluation of cinobufotalin as a potential anti-lung cancer agent.
Lung Neoplasms
Protein expression profiling identifies macrophage migration inhibitory factor and cyclophilin a as potential molecular targets in non-small cell lung cancer.
Lung Neoplasms
RNA interference-mediated gene silencing of cyclophilin A enhances the radiosensitivity of PAa human lung adenocarcinoma cells in vitro.
Lung Neoplasms
Selective targeting p53(WT) lung cancer cells harboring homozygous p53 Arg72 by an inhibitor of CypA.
Lung Neoplasms
Stable RNA interference-mediated suppression of cyclophilin A diminishes non-small-cell lung tumor growth in vivo.
Lung Neoplasms
The mitochondrial cyclophilin D/p53 complexation mediates doxorubicin-induced non-apoptotic death of A549 lung cancer cells.
Lung Neoplasms
Throughput and efficiency of a mass spectrometry-based screening assay for protein-ligand binding detection.
Lung Neoplasms
Translating biomarkers into clinical practice: prognostic implications of cyclophilin A and macrophage migratory inhibitory factor identified from protein expression profiles in non-small cell lung cancer.
Lung Neoplasms
[Expression of pin1 mRNA in the circulation of non-small cell lung cancer patients and influence of sequence of vessel ligation]
Lupus Erythematosus, Cutaneous
Clinical and laboratory characteristics of Finnish lupus erythematosus patients with cutaneous manifestations.
Lupus Erythematosus, Discoid
Clinical and laboratory characteristics of Finnish lupus erythematosus patients with cutaneous manifestations.
Lupus Erythematosus, Systemic
Autoantibodies against cyclophilin in systemic lupus erythematosus and Lyme disease.
Lupus Erythematosus, Systemic
Increased BCMA expression in lupus marks activated B cells, and BCMA receptor engagement enhances the response to TLR9 stimulation.
Lupus Erythematosus, Systemic
Presence of anti-FKBP12 autoantibodies in patients with liver allografts: its association with allograft rejection.
Lyme Disease
Autoantibodies against cyclophilin in systemic lupus erythematosus and Lyme disease.
Lymphatic Metastasis
Association of increased ligand cyclophilin A and receptor CD147 with hypoxia, angiogenesis, metastasis and prognosis of tongue squamous cell carcinoma.
Lymphatic Metastasis
Elevated FKBP52 expression indicates a poor outcome in patients with breast cancer.
Lymphatic Metastasis
Expression and Significance of Cyclophilin J in Primary Gastric Adenocarcinoma.
Lymphatic Metastasis
FKBP10 Acts as a New Biomarker for Prognosis and Lymph Node Metastasis of Gastric Cancer by Bioinformatics Analysis and in Vitro Experiments.
Lymphoma
Hexavalent chromium-induced apoptosis in Hep3B cells is accompanied by calcium overload, mitochondrial damage, and AIF translocation.
Lymphoma
SIRT3 in Neural Stem Cells Attenuates Microglia Activation-Induced Oxidative Stress Injury Through Mitochondrial Pathway.
Lymphoma
The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein.
Lymphoma, B-Cell
Hexavalent chromium-induced apoptosis in Hep3B cells is accompanied by calcium overload, mitochondrial damage, and AIF translocation.
Lymphoma, Large-Cell, Anaplastic
The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein.
Lymphoma, Non-Hodgkin
Targeting B-lymphocyte stimulator/B-cell activating factor and a proliferation-inducing ligand in hematologic malignancies.
Lymphoma, T-Cell
Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis.
Lymphoma, T-Cell
Molecular dynamics simulations of site point mutations in the TPR domain of cyclophilin 40 identify conformational states with distinct dynamic and enzymatic properties.
Macular Degeneration
The Role of Peptidyl Prolyl Isomerases in Aging and Vascular Diseases.
Malaria
A COMPARISON OF RAPID DIAGNOSTIC TESTING (BY PLASMODIUM LACTATE DEHYDROGENASE), AND QUANTITATIVE BUFFY COAT TECHNIQUE IN MALARIA DIAGNOSIS IN CHILDREN.
Malaria
A comparison of thick smears, QBC malaria, PCR and PATH falciparum malaria test trip in Plasmodium falciparum diagnosis.
Malaria
A multi-walled carbon nanotube-zinc oxide nanofiber based flexible chemiresistive biosensor for malaria biomarker detection.
Malaria
Acute Kidney Injury in Children with Plasmodium falciparum Malaria: Determinants for Mortality.
Malaria
Bone marrow suppression and severe anaemia associated with persistent Plasmodium falciparum infection in African children with microscopically undetectable parasitaemia.
Malaria
Comparison of a rapid field immunochromatographic test to expert microscopy for the detection of Plasmodium falciparum asexual parasitemia in Thailand.
Malaria
Correlation of biomarkers for parasite burden and immune activation with acute kidney injury in severe falciparum malaria.
Malaria
Crystal structure of Plasmodium vivax FK506-binding protein 25 reveals conformational changes responsible for its noncanonical activity.
Malaria
Detailed characterization of a cyclophilin from the human malaria parasite Plasmodium falciparum.
Malaria
Detection of histidine rich protein & lactate dehydrogenase of Plasmodium falciparum in malaria patients by sandwich ELISA using in-house reagents.
Malaria
Detection of histidine rich protein 2 and panmalarial ICT Malaria Pf/Pv test antigens after chloroquine treatment of uncomplicated falciparum malaria does not reliably predict treatment outcome in eastern Indonesia.
Malaria
Evaluation of two tests based on the detection of histidine rich protein 2 for the diagnosis of imported Plasmodium falciparum malaria.
Malaria
High prevalence and extended deletions in Plasmodium falciparum hrp2/3 genomic loci in Ethiopia.
Malaria
HRP2 and HRP3 cross-reactivity and implications for HRP2-based RDT use in regions with Plasmodium falciparum hrp2 gene deletions.
Malaria
Malaria diagnosis: false negative parasight-F tests in falciparum malaria patients in Nigeria.
Malaria
Molecular and biochemical characterization of a Plasmodium falciparum cyclophilin containing a cleavable signal sequence.
Malaria
Molecular surveillance reveals the presence of pfhrp2 and pfhrp3 gene deletions in Plasmodium falciparum parasite populations in Uganda, 2017-2019.
Malaria
Paracheck-Pf accuracy and recently treated Plasmodium falciparum infections: is there a risk of over-diagnosis?
Malaria
Performance evaluation of a prototype rapid diagnostic test for combined detection of gambiense human African trypanosomiasis and malaria.
Malaria
Performance of Antigen Concentration Thresholds for Attributing Fever to Malaria among Outpatients in Angola.
Malaria
Performance of malaria rapid diagnostic test in febrile under-five children at Oni Memorial Children's Hospital in Ibadan, Nigeria, 2016.
Malaria
Prevalence and clinical impact of malaria infections detected with a highly sensitive HRP2 rapid diagnostic test in Beninese pregnant women.
Malaria
Prevalence of pfhrp2 and/or pfhrp3 Gene Deletion in Plasmodium falciparum Population in Eight Highly Endemic States in India.
Malaria
Prevalence of Plasmodium falciparum isolates lacking the histidine rich protein 2 gene among symptomatic malaria patients in Kwilu Province of the Democratic Republic of Congo.
Malaria
Sequence variation in Plasmodium falciparum Histidine Rich Proteins 2 and 3 in Indian isolates: Implications for Malaria Rapid Diagnostic Test Performance.
Malaria
Targeting the hemozoin synthesis pathway for new antimalarial drug discovery: technologies for in vitro beta-hematin formation assay.
Malaria
The FK506-binding protein of the malaria parasite, Plasmodium falciparum, is a FK506-sensitive chaperone with FK506-independent calcineurin-inhibitory activity.
Malaria
Trial of the ParaSight-F test for malaria diagnosis in the primary health care system, Zimbabwe.
Malaria
Ultra-sensitive RDT performance and antigen dynamics in a high-transmission Plasmodium falciparum setting in Mali.
Malaria, Cerebral
Variations in the C-terminal repeats of the knob-associated histidine-rich protein of Plasmodium falciparum.
Malaria, Falciparum
Evaluation of two tests based on the detection of histidine rich protein 2 for the diagnosis of imported Plasmodium falciparum malaria.
Malaria, Vivax
Identification of cryptic coinfection with Plasmodium falciparum in patients presenting with vivax malaria.
Malnutrition
Eczematous reactions to food in atopic eczema: position paper of the EAACI and GA2LEN.
Malnutrition
The housekeeping genes GAPDH and cyclophilin are regulated by metabolic state in the liver of dairy cows.
Marfan Syndrome
Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients.
Mastitis
Transcriptome Analysis of The Inflammatory Responses of Bovine Mammary Epithelial Cells: Exploring Immunomodulatory Target Genes for Bovine Mastitis.
Melanoma
A novel interaction between calcium-modulating cyclophilin ligand and Basigin regulates calcium signaling and matrix metalloproteinase activities in human melanoma cells.
Melanoma
ABT-737 sensitizes curcumin-induced anti-melanoma cell activity through facilitating mPTP death pathway.
Melanoma
Alternative macrophage polarisation associated with resistance to anti-PD1 blockade is possibly supported by the splicing of FKBP51 immunophilin in melanoma patients.
Melanoma
Characterization of human melanoma cell lines and melanocytes by proteome analysis.
Melanoma
Comparative proteomic analysis of matched primary and metastatic melanoma cell lines.
Melanoma
Curcumin-induced melanoma cell death is associated with mitochondrial permeability transition pore (mPTP) opening.
Melanoma
FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential.
Melanoma
FKBP51 employs both scaffold and isomerase functions to promote NF-?B activation in melanoma.
Melanoma
Immunomodulatory pathways regulate expression of a spliced FKBP51 isoform in lymphocytes of melanoma patients.
Melanoma
Inhibition of peptidyl-prolyl isomerase (PIN1) and BRAF signaling to target melanoma.
Melanoma
Integration of zebrafish fin regeneration genes with expression data of human tumors in silico uncovers potential novel melanoma markers.
Melanoma
Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasis.
Melanoma
Rapamycin inhibits doxorubicin-induced NF-kappaB/Rel nuclear activity and enhances the apoptosis of melanoma cells.
Melanoma
RNA-interference-mediated downregulation of Pin1 suppresses tumorigenicity of malignant melanoma A375 cells.
Melanoma
Role of FK506-binding protein 51 in the control of apoptosis of irradiated melanoma cells.
Melanoma
TRAF2 and FKBP51 as possible markers for identification of suitable melanoma tumors for tumor necrosis factor-? inhibition.
Memory Disorders
Novel effects on memory observed following unilateral intracranial administration of okadaic acid, cyclosporin A, FK506 and [MeVal4]CyA.
Meningioma
Overexpression of aryl hydrocarbon receptor (AHR) signalling pathway in human meningioma.
Mesenteric Ischemia
Management of Acute Mesenteric Venous Thrombosis: A Systematic Review of Contemporary Studies.
Metabolic Syndrome
Elevated Serum Cyclophilin B Levels Are Associated with the Prevalence and Severity of Metabolic Syndrome.
Metabolic Syndrome
Focus on FKBP51: A molecular link between stress and metabolic disorders.
Metrorrhagia
Quantitative analysis of NIM811, a cyclophilin inhibitor, in human dried blood spots using liquid chromatography-tandem mass spectrometry.
Microcephaly
Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly.
Migraine Disorders
Alcohol and migraine: trigger factor, consumption, mechanisms. A review.
Migraine Disorders
Alcoholic beverages as trigger factor and the effect on alcohol consumption behavior in patients with migraine.
Migraine Disorders
Changes in visual-evoked potential habituation induced by hyperventilation in migraine.
Migraine Disorders
Geomagnetic activity, humidity, temperature and headache: is there any correlation?
Migraine Disorders
Myofascial Trigger Points and Migraine-related Disability in Women with Episodic and Chronic Migraine.
Migraine Disorders
Reversible cerebral vasoconstriction phenomena following indomethacin administration.
Migraine Disorders
Trigger factors mainly from the environmental type are reported by adolescents with migraine.
Migraine Disorders
[Primary cephaleas. A revision of its diagnosis and therapeutic approach]
Migraine with Aura
Reversible cerebral vasoconstriction phenomena following indomethacin administration.
Migraine without Aura
What turns on a migraine? A systematic review of migraine precipitating factors.
Mitochondrial Myopathies
Cyclophilin D, a target for counteracting skeletal muscle dysfunction in mitochondrial myopathy.
Motor Neuron Disease
Expression of FKBP12 and ryanodine receptors (RyRs) in the spinal cord of MND patients.
Motor Neuron Disease
FKBP12 immunoreactivity in the human spinal cord of motor neuron disease patients.
Mouth Neoplasms
Differential gene expression in neoplastic and human papillomavirus-immortalized oral keratinocytes.
Multiple Myeloma
Cyclophilin A as a downstream effector of PI3K/Akt signalling pathway in multiple myeloma cells.
Multiple Myeloma
Targeting B-lymphocyte stimulator/B-cell activating factor and a proliferation-inducing ligand in hematologic malignancies.
Multiple Myeloma
The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells.
Multiple Sclerosis
Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis.
Multiple Sclerosis
The P66Shc/mitochondrial permeability transition pore pathway determines neurodegeneration.
Muscle Hypotonia
The novel missense mutation Met48Lys in FKBP22 changes its structure and functions.
Muscular Atrophy
Redox modification of ryanodine receptor contributes to impaired Ca2+ homeostasis and exacerbates muscle atrophy under high altitude.
Muscular Diseases
A substrate preference for the rough endoplasmic reticulum resident protein FKBP22 during collagen biosynthesis.
Muscular Diseases
Melanocytes from Patients Affected by Ullrich Congenital Muscular Dystrophy and Bethlem Myopathy have Dysfunctional Mitochondria That Can be Rescued with Cyclophilin Inhibitors.
Muscular Diseases
NIM811, a cyclophilin inhibitor without immunosuppressive activity, is beneficial in collagen VI congenital muscular dystrophy models.
Muscular Dystrophies
Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice.
Muscular Dystrophies
Genetic ablation of cyclophilin D rescues mitochondrial defects and prevents muscle apoptosis in collagen VI myopathic mice.
Muscular Dystrophies
Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy.
Muscular Dystrophies
Genetic heterogeneity of left-ventricular noncompaction cardiomyopathy.
Muscular Dystrophies
Melanocytes from Patients Affected by Ullrich Congenital Muscular Dystrophy and Bethlem Myopathy have Dysfunctional Mitochondria That Can be Rescued with Cyclophilin Inhibitors.
Muscular Dystrophies
NIM811, a cyclophilin inhibitor without immunosuppressive activity, is beneficial in collagen VI congenital muscular dystrophy models.
Muscular Dystrophies
The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muscle apoptosis and ultrastructural defects in Col6a1(-/-) myopathic mice.
Muscular Dystrophy, Duchenne
Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy.
Muscular Dystrophy, Duchenne
Investigation of Debio 025, a cyclophilin inhibitor, in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy.
Muscular Dystrophy, Emery-Dreifuss
Genetic heterogeneity of left-ventricular noncompaction cardiomyopathy.
Myasthenia Gravis
Chemotherapy-induced myasthenic crisis in thymoma treated with primary chemotherapy with curative intent on mechanical ventilation: a case report and review of the literature.
Mycoplasma Infections
Fuchs' syndrome (Stevens-Johnson syndrome without skin involvement) in an adult male--a case report and general characteristics of the sporadically diagnosed disease.
Myocardial Infarction
A search for cyclophilin-A gene (PPIA) variation and its contribution to the risk of atherosclerosis and myocardial infarction.
Myocardial Infarction
Activation of G Protein-Coupled Estrogen Receptor 1 At the Onset of Reperfusion Protects the Myocardium Against Ischemia/Reperfusion Injury by Reducing Mitochondrial Dysfunction and Mitophagy.
Myocardial Infarction
Circulating levels of inflammatory parameters pentraxin-3, cyclophilin and heparin-binding epidermal growth factor-like growth factor in patients with ST-elevation myocardial infarction.
Myocardial Infarction
Decrease in plasma cyclophilin A concentration at 1 month after myocardial infarction predicts better left ventricular performance and synchronicity at 6 months: a pilot study in patients with ST elevation myocardial infarction.
Myocardial Infarction
Ivabradine Induces Cardiac Protection against Myocardial Infarction by Preventing Cyclophilin-A Secretion in Pigs under Coronary Ischemia/Reperfusion.
Myocardial Infarction
miR-146a inhibits mitochondrial dysfunction and myocardial infarction by targeting cyclophilin D.
Myocardial Infarction
Mitochondrial permeability transition in cardiac ischemia-reperfusion: whether cyclophilin D is a viable target for cardioprotection?
Myocardial Infarction
Oxidative Stress and Inflammatory Markers PTX3, CypA, and HB-EGF: How Are They Linked in Patients With STEMI?
Myocardial Infarction
Platelet-bound cyclophilin A in patients with stable coronary artery disease and acute myocardial infarction.
Myocardial Infarction
SP-8356, a Novel Inhibitor of CD147-Cyclophilin A Interactions, Reduces Plaque Progression and Stabilizes Vulnerable Plaques in apoE-Deficient Mice.
Myocardial Ischemia
The cardioprotective effect of necrostatin requires the cyclophilin-D component of the mitochondrial permeability transition pore.
Myocardial Ischemia
[Clinical characteristics of patients diagnosed of chronic heart failure attended in Primary Care. The CARDIOPRES study]
Myocardial Reperfusion Injury
Extracellular cyclophilin A may be a potential target to protect against myocardial reperfusion injury.
Myocardial Reperfusion Injury
Inhibition of myocardial reperfusion injury by ischemic postconditioning requires sirtuin 3-mediated deacetylation of cyclophilin D.
Myocarditis
Cyclophilin A affects inflammation, virus elimination and myocardial fibrosis in coxsackievirus B3-induced myocarditis.
Myocarditis
The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis.
Myopathy, Central Core
Regulation of the Skeletal Muscle Ryanodine Receptor/Ca2+-release Channel RyR1 by S-Palmitoylation.
Myositis Ossificans
ALK2 Receptor Kinase Association with FKBP12.6 Is Structurally Conserved with the ALK2-FKBP12 Complex.
nad(p)h oxidase (h2o2-forming) deficiency
Molecular Mechanisms of the Crosstalk Between Mitochondria and NADPH Oxidase Through Reactive Oxygen Species-Studies in White Blood Cells and in Animal Models.
Nasopharyngeal Carcinoma
Epstein-Barr Virus Nuclear Antigen 1 Recruits Cyclophilin A to Facilitate the Replication of Viral DNA Genome.
Nasopharyngeal Carcinoma
Exosomal cyclophilin A as a novel noninvasive biomarker for Epstein-Barr virus associated nasopharyngeal carcinoma.
Neoplasm Metastasis
A novel interaction between calcium-modulating cyclophilin ligand and Basigin regulates calcium signaling and matrix metalloproteinase activities in human melanoma cells.
Neoplasm Metastasis
Association of increased ligand cyclophilin A and receptor CD147 with hypoxia, angiogenesis, metastasis and prognosis of tongue squamous cell carcinoma.
Neoplasm Metastasis
Ca2+/S100 proteins inhibit the interaction of FKBP38 with Bcl-2 and Hsp90.
Neoplasm Metastasis
Cyclophilin A Inhibitor Debio-025 Targets Crk, Reduces Metastasis, and Induces Tumor Immunogenicity in Breast Cancer.
Neoplasm Metastasis
Cyclophilin A promotes human hepatocellular carcinoma cell metastasis via regulation of MMP3 and MMP9.
Neoplasm Metastasis
Cyclophilin A promotes non-small cell lung cancer metastasis via p38 MAPK.
Neoplasm Metastasis
Downregulation of cyclophilin A by siRNA diminishes non-small cell lung cancer cell growth and metastasis via the regulation of matrix metallopeptidase 9.
Neoplasm Metastasis
Elevated FKBP52 expression indicates a poor outcome in patients with breast cancer.
Neoplasm Metastasis
Expression and localization of the immunophilin FKBP51 in colorectal carcinomas and primary metastases, and alterations following oxaliplatin-based chemotherapy.
Neoplasm Metastasis
Expression and Significance of Cyclophilin J in Primary Gastric Adenocarcinoma.
Neoplasm Metastasis
Expression of Cyclophilin A in Gastric Adenocarcinoma Patients and Its Inverse Association with Local Relapses and Distant Metastasis.
Neoplasm Metastasis
FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential.
Neoplasm Metastasis
FKBP10 Acts as a New Biomarker for Prognosis and Lymph Node Metastasis of Gastric Cancer by Bioinformatics Analysis and in Vitro Experiments.
Neoplasm Metastasis
FKBP51 acts as a biomarker of early metastasis and is related to carmustine sensitivity in human glioma cells.
Neoplasm Metastasis
FKBP51 promotes migration and invasion of papillary thyroid carcinoma through NF-?B-dependent epithelial-to-mesenchymal transition.
Neoplasm Metastasis
FKBP65-dependent peptidyl-prolyl isomerase activity potentiates the lysyl hydroxylase 2-driven collagen cross-link switch.
Neoplasm Metastasis
Inhibition of the Activity of Cyclophilin A Impedes Prolactin Receptor-Mediated Signaling, Mammary Tumorigenesis, and Metastases.
Neoplasm Metastasis
Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasis.
Neoplasm Metastasis
Localization of sporadic neuroendocrine tumors by gene expression analysis of their metastases.
Neoplasm Metastasis
The search for the primary tumor in metastasized gastroenteropancreatic neuroendocrine neoplasm.
Neoplasms
1-(2,6-Dibenzyloxybenzoyl)-3-(9H-fluoren-9-yl)-urea: A novel cyclophilin A allosteric activator.
Neoplasms
12(S)-HETE induces lymph endothelial cell retraction in vitro by upregulation of SOX18.
Neoplasms
A COMPARISON OF RAPID DIAGNOSTIC TESTING (BY PLASMODIUM LACTATE DEHYDROGENASE), AND QUANTITATIVE BUFFY COAT TECHNIQUE IN MALARIA DIAGNOSIS IN CHILDREN.
Neoplasms
A cyclophilin B gene encodes antigenic epitopes recognized by HLA-A24-restricted and tumor-specific CTLs.
Neoplasms
A molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomography.
Neoplasms
A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models.
Neoplasms
Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition.
Neoplasms
Age-related changes in BAFF and APRIL profiles and upregulation of BAFF and APRIL expression in patients with primary antibody deficiency.
Neoplasms
Allelic loss of cyclophilin 40, an estrogen receptor-associated immunophilin, in breast carcinomas.
Neoplasms
An APRIL-based chimeric antigen receptor for dual targeting of BCMA and TACI in multiple myeloma.
Neoplasms
Anesthesia for euthanasia influences mRNA expression in healthy mice and after traumatic brain injury.
Neoplasms
Apoptosis, mitosis and cyclophilin-40 expression in regressing peroxisome proliferator-induced adenomas.
Neoplasms
APRIL and BAFF Proteins Increase Proliferation of Human Adipose-Derived Stem Cells Through Activation of Erk1/2 MAP Kinase.
Neoplasms
Association of BSG genetic polymorphisms with atherosclerotic cerebral infarction in the Han Chinese population.
Neoplasms
BAFF supports human B cell differentiation in the lymphoid follicles through distinct receptors.
Neoplasms
BAFF-R gene induced by IFN-? in multiple myeloma cells is related to NF-?B signals.
Neoplasms
Benzo[a]pyrene Potentiates the Pathogenesis of Abdominal Aortic Aneurysms in Apolipoprotein E Knockout Mice.
Neoplasms
Binding modes and conformational changes of FK506-binding protein 51 induced by inhibitor bindings: insight into molecular mechanisms based on multiple simulation technologies.
Neoplasms
Bioluminescence resonance energy transfer (BRET) imaging of protein-protein interactions within deep tissues of living subjects.
Neoplasms
Breast cancer proteomics by laser capture microdissection, sample pooling, 54-cm IPG IEF, and differential iodine radioisotope detection.
Neoplasms
CD147-Cyclophilin a Interactions Promote Proliferation and Survival of Cutaneous T-Cell Lymphoma.
Neoplasms
cDNA microarray analysis of differential gene expression in gastric cancer cells sensitive and resistant to 5-Fluorouracil and Cisplatin.
Neoplasms
Cell size regulation by the human TSC tumor suppressor proteins depends on PI3K and FKBP38.
Neoplasms
Characterization of surface binding sites for cyclophilin B on a human tumor T-cell line.
Neoplasms
Chemical Tools for Studying the Impact of cis/trans Prolyl Isomerization on Signaling: A Case Study on RNA Polymerase II Phosphatase Activity and Specificity.
Neoplasms
Chemotherapy-induced myasthenic crisis in thymoma treated with primary chemotherapy with curative intent on mechanical ventilation: a case report and review of the literature.
Neoplasms
Co-expression network analysis of gene expression profiles of HER2+ breast cancer-associated brain metastasis.
Neoplasms
Commitment of Scaffold Proteins in the Onco-Biology of Human Colorectal Cancer and Liver Metastases after Oxaliplatin-Based Chemotherapy.
Neoplasms
Comprehensive evaluation of FKBP10 expression and its prognostic potential in gastric cancer.
Neoplasms
Conformation-Directed Catalysis and Coupled Enzyme-Substrate Dynamics in Pin1 Phosphorylation-Dependent Cis-Trans Isomerase.
Neoplasms
COT phosphorylates prolyl-isomerase Pin1 to promote tumorigenesis in breast cancer.
Neoplasms
Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge.
Neoplasms
Cyclophilin 40 alters UVA-induced apoptosis and mitochondrial ROS generation in keratinocytes.
Neoplasms
Cyclophilin A (CypA) interacts with NF-?B subunit, p65/RelA, and contributes to NF-?B activation signaling.
Neoplasms
Cyclophilin A enhances cell proliferation and tumor growth of liver fluke-associated cholangiocarcinoma.
Neoplasms
Cyclophilin A Enhances Cell Proliferation and Xenografted Tumor Growth of Early Gastric Cancer.
Neoplasms
Cyclophilin A Function in Mammary Epithelium Impacts Jak2/Stat5 Signaling, Morphogenesis, Differentiation, and Tumorigenesis in the Mammary Gland.
Neoplasms
Cyclophilin A Inhibitor Debio-025 Targets Crk, Reduces Metastasis, and Induces Tumor Immunogenicity in Breast Cancer.
Neoplasms
Cyclophilin A is a factor of antitumor defense in the early stages of tumor development.
Neoplasms
Cyclophilin A is overexpressed in human pancreatic cancer cells and stimulates cell proliferation through CD147.
Neoplasms
Cyclophilin A-EMMPRIN interaction induces invasion of head and neck squamous cell carcinoma.
Neoplasms
Cyclophilin B expression is associated with in vitro radioresistance and clinical outcome after radiotherapy.
Neoplasms
Cyclophilin B is involved in p300-mediated degradation of CHOP in tumor cell adaptation to hypoxia.
Neoplasms
Cyclophilin D counteracts P53-mediated growth arrest and promotes Ras tumorigenesis.
Neoplasms
Cyclophilin D, a component of the permeability transition-pore, is an apoptosis repressor.
Neoplasms
Cyclosporin A does not protect the disruption of the inner mitochondrial membrane potential induced by potassium ionophores in intact K562 cells.
Neoplasms
Decoding Allosteric Communication Pathways in Cyclophilin A with a Comparative Analysis of Perturbed Conformational Ensembles.
Neoplasms
Decursin Exerts Anti-cancer Activity in MDA-MB-231 Breast Cancer Cells Via Inhibition of the Pin1 Activity and Enhancement of the Pin1/p53 Association.
Neoplasms
Development of a microarray for studying porcine cytokine production in blood mononuclear cells and intestinal biopsies.
Neoplasms
Diagnostic markers for CNS lymphoma in blood and cerebrospinal fluid: a systematic review.
Neoplasms
Different redox states in malignant and non-malignant esophageal epithelial cells and differential cytotoxic responses to bile acid and honokiol.
Neoplasms
Discovery of 4,6-bis(benzyloxy)-3-phenylbenzofuran as a novel Pin1 inhibitor to suppress hepatocellular carcinoma via upregulating microRNA biogenesis.
Neoplasms
Discovery of novel cyclophilin a ligands using an h/d exchange- and mass spectrometry-based strategy.
Neoplasms
Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
Neoplasms
Disentangling mechanisms involved in collagen pyridinoline cross-linking: The immunophilin FKBP65 is critical for dimerization of lysyl hydroxylase 2.
Neoplasms
Downregulation of cyclophilin A by siRNA diminishes non-small cell lung cancer cell growth and metastasis via the regulation of matrix metallopeptidase 9.
Neoplasms
Downregulation of microRNA-370 in esophageal squamous-cell carcinoma is associated with cancer progression and promotes cancer cell proliferation via upregulating PIN1.
Neoplasms
Downregulation of Peptidylprolyl isomerase A promotes cell death and enhances doxorubicin-induced apoptosis in hepatocellular carcinoma.
Neoplasms
Effect of chronic coadministration of endotoxin and ethanol on rat liver pathology and proinflammatory and anti-inflammatory cytokines.
Neoplasms
Elevated FKBP52 expression indicates a poor outcome in patients with breast cancer.
Neoplasms
Endoplasmic reticulum vacuolation and unfolded protein response leading to paraptosis like cell death in cyclosporine A treated cancer cervix cells is mediated by cyclophilin B inhibition.
Neoplasms
Enhanced Sampling of Interdomain Motion Using Map-Restrained Langevin Dynamics and NMR: Application to Pin1.
Neoplasms
Erastin Disrupts Mitochondrial Permeability Transition Pore (mPTP) and Induces Apoptotic Death of Colorectal Cancer Cells.
Neoplasms
Establishment and characterisation of testicular cancer patient-derived xenograft models for preclinical evaluation of novel therapeutic strategies.
Neoplasms
Expression and localization of the immunophilin FKBP51 in colorectal carcinomas and primary metastases, and alterations following oxaliplatin-based chemotherapy.
Neoplasms
Expression of Cyclophilin A in Gastric Adenocarcinoma Patients and Its Inverse Association with Local Relapses and Distant Metastasis.
Neoplasms
Expression of FK506 binding protein 65 (FKBP65) is decreased in epithelial ovarian cancer cells compared to benign tumor cells and to ovarian epithelium.
Neoplasms
Expression of leucocyte chemoattractants by interstitial renal fibroblasts: up-regulation by drugs associated with interstitial fibrosis.
Neoplasms
Expression of the estrogen receptor-associated immunophilins, cyclophilin 40 and FKBP52, in breast cancer.
Neoplasms
Expressions of BAFF/BAFF receptors and their correlation with disease activity in Chinese SLE patients.
Neoplasms
Extracellular Proton Concentrations Impacts LN229 Glioblastoma Tumor Cell Fate via Differential Modulation of Surface Lipids.
Neoplasms
FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential.
Neoplasms
FKBP10 functioned as a cancer-promoting factor mediates cell proliferation, invasion, and migration via regulating PI3K signaling pathway in stomach adenocarcinoma.
Neoplasms
FKBP10/FKBP65 expression in high-grade ovarian serous carcinoma and its association with patient outcome.
Neoplasms
FKBP12 enhances sensitivity to chemotherapy-induced cancer cell apoptosis by inhibiting MDM2.
Neoplasms
FKBP12 is a predictive biomarker for efficacy of anthracycline-based chemotherapy in breast cancer.
Neoplasms
FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt.
Neoplasms
FKBP51 and FKBP52 regulate androgen receptor dimerization and proliferation in prostate cancer cells.
Neoplasms
FKBP51 promotes assembly of the Hsp90 chaperone complex and regulates androgen receptor signaling in prostate cancer cells.
Neoplasms
FKBP51 promotes migration and invasion of papillary thyroid carcinoma through NF-?B-dependent epithelial-to-mesenchymal transition.
Neoplasms
FKBP65-dependent peptidyl-prolyl isomerase activity potentiates the lysyl hydroxylase 2-driven collagen cross-link switch.
Neoplasms
Focal prostate basal cell layer disruptions and leukocyte infiltration are correlated events: A potential mechanism for basal cell layer disruptions and tumor invasion.
Neoplasms
Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene.
Neoplasms
From cell death to viral replication: the diverse functions of the membrane-associated FKBP38.
Neoplasms
From chemical tools to clinical medicines: nonimmunosuppressive cyclophilin inhibitors derived from the cyclosporin and sanglifehrin scaffolds.
Neoplasms
Functional changes in myeloid-derived suppressor cells (MDSCs) during tumor growth: FKBP51 contributes to the regulation of the immunosuppressive function of MDSCs.
Neoplasms
GRP78/Dna K Is a Target for Nexavar/Stivarga/Votrient in the Treatment of Human Malignancies, Viral Infections and Bacterial Diseases.
Neoplasms
Heat shock proteins, cell survival and drug resistance: the mitochondrial chaperone TRAP1, a potential novel target for ovarian cancer therapy.
Neoplasms
High expression level of peptidylprolyl isomerase A is correlated with poor prognosis of liver hepatocellular carcinoma.
Neoplasms
Honokiol inhibits hepatoma carcinoma cell migration through downregulated Cyclophilin B expression.
Neoplasms
Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity.
Neoplasms
Identification and Validation of Housekeeping Genes for Gene Expression Analysis of Cancer Stem Cells.
Neoplasms
Identification and validation of novel androgen-regulated genes in prostate cancer.
Neoplasms
Identification of aldolase A as a potential diagnostic biomarker for colorectal cancer based on proteomic analysis using formalin-fixed paraffin-embedded tissue.
Neoplasms
Identification of cyclophilin B-derived peptides capable of inducing histocompatibility leukocyte antigen-A2-restricted and tumor-specific cytotoxic T lymphocytes.
Neoplasms
Identification of expressed genes in carp (Cyprinus carpio) head kidney cells after in vitro treatment with immunostimulants.
Neoplasms
Identification of proteins suppressing the functions of oncogenic phosphatase of regenerating liver 1 and 3.
Neoplasms
Imazamethabenz inhibits human breast cancer cell proliferation, migration and invasion via combination with Pin1.
Neoplasms
Immune-associated proteins with potential in vivo anti-tumor activities are upregulated in lung cancer cells treated with umbelliprenin: A proteomic approach.
Neoplasms
Impact of cisplatin administration on protein expression levels in renal cell carcinoma: a proteomic analysis.
Neoplasms
Impaired Dual-Specificity Protein Phosphatase DUSP4 Reduces Corticosteroid Sensitivity.
Neoplasms
In-depth proteome analysis of the rubber particle of Hevea brasiliensis (para rubber tree).
Neoplasms
Induction of vascular endothelial growth factor by peptidyl-prolyl isomerase Pin1 in breast cancer cells.
Neoplasms
Inhibition of peptidyl-prolyl isomerase (PIN1) and BRAF signaling to target melanoma.
Neoplasms
Inhibition of the serine/threonine protein phosphatases PP1 and PP2A in lymphocytes: effect on mRNA levels for interleukin-2, IL-2R alpha, krox-24, p53, hsc70 and cyclophilin.
Neoplasms
Insight into the structural stability of wild-type and histidine mutants in Pin1 by experimental and computational methods.
Neoplasms
Interaction of cyclophilin A with a novel binding protein, SR-25, and characterization of their expression pattern in Chinese hepatocellular carcinoma patients.
Neoplasms
Interaction of Pin1 with Nek6 and characterization of their expression correlation in Chinese hepatocellular carcinoma patients.
Neoplasms
Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasis.
Neoplasms
Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-kappaB.
Neoplasms
Knockdown of Pin1 leads to reduced angiogenic potential and tumorigenicity in glioblastoma cells.
Neoplasms
Knockdown of the prolyl isomerase Pin1 inhibits Hep-2 cell growth, migration, and invasion by targeting the ?-catenin signaling pathway.
Neoplasms
Long non-coding RNA RP11-284F21.9 functions as a ceRNA regulating PPWD1 by competitively binding to miR-769-3p in cervical carcinoma.
Neoplasms
Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies.
Neoplasms
Management of Acute Mesenteric Venous Thrombosis: A Systematic Review of Contemporary Studies.
Neoplasms
MicroRNA-100/99a, deregulated in acute lymphoblastic leukaemia, suppress proliferation and promote apoptosis by regulating the FKBP51 and IGF1R/mTOR signalling pathways.
Neoplasms
Mini Review: Opposing Pathologies in Cancer and Alzheimer's Disease: Does the PI3K/Akt Pathway Provide Clues?
Neoplasms
MiR-629-5p promotes the invasion of lung adenocarcinoma via increasing both tumor cell invasion and endothelial cell permeability.
Neoplasms
miR-874-3p is down-regulated in hepatocellular carcinoma and negatively regulates PIN1 expression.
Neoplasms
Monitoring mouse prostate development by profiling and imaging mass spectrometry.
Neoplasms
Morphological and immunohistochemical features of malignant vascular tumors with special emphasis on GLUT1, and FKBP12 expressions.
Neoplasms
Nonmutated self-antigen-derived cancer vaccine peptides elicit an IgE-independent but mast cell-dependent immediate-type skin reaction without systemic anaphylaxis.
Neoplasms
Novel Cyclophilin Inhibitor Decreases Cell Proliferation and Tumor Growth in Models of Hepatocellular Carcinoma.
Neoplasms
Overexpressed cyclophilin A in cancer cells renders resistance to hypoxia- and cisplatin-induced cell death.
Neoplasms
Overexpression of aryl hydrocarbon receptor (AHR) signalling pathway in human meningioma.
Neoplasms
Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells.
Neoplasms
Peptidyl prolyl cis/trans isomerase activity on the cell surface correlates with extracellular matrix development.
Neoplasms
Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds.
Neoplasms
Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 as a molecular target in breast cancer: a therapeutic perspective of gynecological cancer.
Neoplasms
Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation.
Neoplasms
Peptidyl-prolyl cis/trans isomerase Pin1 regulates withaferin A-mediated cell cycle arrest in human breast cancer cells.
Neoplasms
Peptidyl-prolyl isomerase Pin1 markedly enhances the oncogenic activity of the rel proteins in the nuclear factor-kappaB family.
Neoplasms
Peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (PIN1) regulates pulmonary effects of endotoxin and tumor necrosis factor-? in mice.
Neoplasms
PIN1 genetic polymorphisms and the susceptibility of HBV-related hepatocellular carcinoma in a Guangxi population.
Neoplasms
Pin1 induction in the fibrotic liver and its roles in TGF-?1 expression and Smad2/3 phosphorylation.
Neoplasms
Pin1 is required for ultraviolet A-stimulated cyclooxygenase-2 induction in mouse epidermal cells.
Neoplasms
Pin1 promotes prostate cancer cell proliferation and migration through activation of Wnt/?-catenin signaling.
Neoplasms
Proliferation of NS0 cells in protein-free medium: the role of cell-derived proteins, known growth factors and cellular receptors.
Neoplasms
Prolyl isomerase Pin1 negatively regulates the stability of SUV39H1 to promote tumorigenesis in breast cancer.
Neoplasms
Protein alterations in infiltrating ductal carcinomas of the breast as detected by nonequilibrium pH gradient electrophoresis and mass spectrometry.
Neoplasms
Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry.
Neoplasms
Protein expression profiling identifies cyclophilin A as a molecular target in Fhit-mediated tumor suppression.
Neoplasms
Protein expression profiling identifies macrophage migration inhibitory factor and cyclophilin a as potential molecular targets in non-small cell lung cancer.
Neoplasms
Proteomic analysis and identification of new biomarkers and therapeutic targets for invasive ovarian cancer.
Neoplasms
Proteomics identification of cyclophilin a as a potential prognostic factor and therapeutic target in endometrial carcinoma.
Neoplasms
Rapamycin destabilizes interleukin-3 mRNA in autocrine tumor cells by a mechanism requiring an intact 3' untranslated region.
Neoplasms
Reference gene selection for quantitative real-time reverse-transcriptase PCR in orchardgrass subjected to various abiotic stresses.
Neoplasms
Regulated necrosis-related molecule mRNA expression in humans and mice and in murine acute tissue injury and systemic autoimmunity leading to progressive organ damage, and progressive fibrosis.
Neoplasms
Release of overexpressed CypB activates ERK signaling through CD147 binding for hepatoma cell resistance to oxidative stress.
Neoplasms
Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes.
Neoplasms
Retraction: Protein Expression Profiling Identifies Cyclophilin A as a Molecular Target in Fhit-Mediated Tumor Suppression.
Neoplasms
RNA-interference-mediated downregulation of Pin1 suppresses tumorigenicity of malignant melanoma A375 cells.
Neoplasms
Role of FK506-binding protein 51 in the control of apoptosis of irradiated melanoma cells.
Neoplasms
Shrimp miRNA suppresses the stemness of human cancer stem cells via the PIN1 pathway.
Neoplasms
Signals regulating necrosis of cardiomyoblast by BTG2(/TIS21/PC3) via activation of GSK3? and opening of mitochondrial permeability transition pore in response to H2O2.
Neoplasms
Small family with key contacts: par14 and par17 parvulin proteins, relatives of pin1, now emerge in biomedical research.
Neoplasms
Spectroscopic and computational studies on the binding interaction between gallic acid and Pin1.
Neoplasms
Spongionella Secondary Metabolites, Promising Modulators of Immune Response through CD147 Receptor Modulation.
Neoplasms
Stable RNA interference-mediated suppression of cyclophilin A diminishes non-small-cell lung tumor growth in vivo.
Neoplasms
Structural analysis of the mitotic regulator hPin1 in solution: insights into domain architecture and substrate binding.
Neoplasms
Suppression of apoptosis by cyclophilin D via stabilization of hexokinase II mitochondrial binding in cancer cells.
Neoplasms
Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway.
Neoplasms
Synthesis and Evaluation of Dibenzothiophene Analogues as Pin1 Inhibitors for Cervical Cancer Therapy.
Neoplasms
Targeting B-lymphocyte stimulator/B-cell activating factor and a proliferation-inducing ligand in hematologic malignancies.
Neoplasms
Targeting treatment-resistant breast cancer stem cells with FKBPL and its peptide derivative, AD-01, via the CD44 pathway.
Neoplasms
The -842G/C Polymorphisms of PIN1 Contributes to Cancer Risk: A Meta-Analysis of 10 Case-Control Studies.
Neoplasms
The analysis of expressed genes in head kidney of common carp Cyprinus carpio L. stimulated with peptidoglycan.
Neoplasms
The Caenorhabditis elegans parvulin gene subfamily and their expression under cold or heat stress along with the fkb subfamily.
Neoplasms
The FK506-binding immunophilin FKBP51 is transcriptionally regulated by progestin and attenuates progestin responsiveness.
Neoplasms
The myoepithelial cell layer may serve as a potential trigger factor for different outcomes of stage-matched invasive lobular and ductal breast cancers.
Neoplasms
The N-terminal cyclophilin-homologous domain of a 150-kilodalton tumor recognition molecule exhibits both peptidylprolyl cis-trans-isomerase and chaperone activities.
Neoplasms
The nonreceptor tyrosine kinase SRMS inhibits autophagy and promotes tumor growth by phosphorylating the scaffolding protein FKBP51.
Neoplasms
The peptidyl prolyl cis/trans isomerase Pin1 downregulates the Inhibitor of Apoptosis Protein Survivin.
Neoplasms
The prognostic value of stromal FK506-binding protein 1 and androgen receptor in prostate cancer outcome.
Neoplasms
The prolyl cis/trans isomerase cyclophilin 18 interacts with the tumor suppressor p53 and modifies its functions in cell cycle regulation and apoptosis.
Neoplasms
The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor ? in breast cancer.
Neoplasms
The prolyl isomerase pin1 regulates mRNA levels of genes with short half-lives by targeting specific RNA binding proteins.
Neoplasms
The role of FKBP51 in the prognosis of ulcerative colitis-associated colorectal cancer.
Neoplasms
The search for the primary tumor in metastasized gastroenteropancreatic neuroendocrine neoplasm.
Neoplasms
The Stimulation of CD147 Induces MMP-9 Expression through ERK and NF-kappaB in Macrophages: Implication for Atherosclerosis.
Neoplasms
The strong induction of metallothionein gene following cadmium exposure transiently affects the expression of many genes in Eisenia fetida: a trade-off mechanism?
Neoplasms
Thermodynamic analysis of cyclosporin a binding to cyclophilin a in a lung tumor tissue lysate.
Neoplasms
Tissue Proteomics Reveals Differential and Compartment-Specific Expression of the Homologs Transgelin and Transgelin-2 in Lung Adenocarcinoma and Its Stroma.
Neoplasms
TNF Induces Pathogenic Programmed Macrophage Necrosis in Tuberculosis through a Mitochondrial-Lysosomal-Endoplasmic Reticulum Circuit.
Neoplasms
TRAF2 and FKBP51 as possible markers for identification of suitable melanoma tumors for tumor necrosis factor-? inhibition.
Neoplasms
Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1.
Neoplasms
Tumor-Associated Fibronectin Targeted Liposomal Nanoplatform for Cyclophilin A siRNA Delivery and Targeted Malignant Glioblastoma Therapy.
Neoplasms
Two-dimensional gel electrophoresis of Caenorhabditis elegans homogenates and identification of protein spots by microsequencing.
Neoplasms
USP53 promotes apoptosis and inhibits glycolysis in lung adenocarcinoma through FKBP51-AKT1 signaling.
Neoplasms
Words of wisdom. Re: Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells.
Neoplasms
[Expression and clinical significance of pin1 and cyclin d1 in cervical cancer cell lines and cervical epithelial tissues.]
Neoplasms
[Expression of pin1 mRNA in the circulation of non-small cell lung cancer patients and influence of sequence of vessel ligation]
Neoplasms
[Proteomic analysis on portal vein tumor thrombus-associated proteins for hepatocellular carcinoma]
Neoplasms
[Recommendations for the Use of Indirect and Direct Anticoagulants for Long-Term Prophylaxis after Venous Thromboembolism].
Nephrotic Syndrome
A study of gene expression of cyclophilin in childhood refractory nephrotic syndrome and its clinical significance.
Nervous System Diseases
Neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons.
Nervous System Diseases
Non-FK506-binding protein-12 neuroimmunophilin ligands increase neurite elongation and accelerate nerve regeneration.
Neuralgia
Silencing of FKBP51 alleviates the mechanical pain threshold, inhibits DRG inflammatory factors and pain mediators through the NF-kappaB signaling pathway.
Neuralgia
The Stress Regulator Fkbp51: A Novel and Promising Druggable Target for the Treatment of Persistent Pain States Across Sexes.
Neuroblastoma
Cyclophilin B protects SH-SY5Y human neuroblastoma cells against MPP(+)-induced neurotoxicity via JNK pathway.
Neuroblastoma
Cyclosporin A regulates the levels of cyclophilin A in neuroblastoma cells in culture.
Neuroblastoma
Effects of altered cyclophilin A expression on growth and differentiation of human and mouse neuronal cells.
Neuroblastoma
Hsp90-mediated inhibition of FKBP38 regulates apoptosis in neuroblastoma cells.
Neuroblastoma
Mitochondrial targeting of cyclosporin A enables selective inhibition of cyclophilin-D and enhanced cytoprotection after glucose and oxygen deprivation.
Neuroblastoma
Redox characterization of human cyclophilin D: Identification of a new mammalian mitochondrial redox sensor?
Neuroblastoma
The specific FKBP38 inhibitor N-(N',N'-dimethylcarboxamidomethyl)cycloheximide has potent neuroprotective and neurotrophic properties in brain ischemia.
Neurodegenerative Diseases
Alzheimer's disease-causing proline substitutions lead to presenilin 1 aggregation and malfunction.
Neurodegenerative Diseases
Bioinspired Hybrid Fluorescent Ligands for the FK1 Domain of FKBP52.
Neurodegenerative Diseases
Classical force field parameters for two high-affinity ligands of FKBP12.
Neurodegenerative Diseases
Conformational switch of polyglutamine-expanded huntingtin into benign aggregates leads to neuroprotective effect.
Neurodegenerative Diseases
Cyclophilin D-dependent mitochondrial permeability transition is not involved in neurodegeneration in mnd2 mutant mice.
Neurodegenerative Diseases
Failure of GPI compounds to display neurotrophic activity in vitro and in vivo.
Neurodegenerative Diseases
From cell death to viral replication: the diverse functions of the membrane-associated FKBP38.
Neurodegenerative Diseases
Immunophilins and their ligands: insights into survival and growth of human neurons.
Neurodegenerative Diseases
Mitochondrial permeability transition pore is a potential drug target for neurodegeneration.
Neurodegenerative Diseases
Modeling and synthesis of non-cyclic derivatives of GPI-1046 as potential FKBP ligands with neurotrophic properties.
Neurodegenerative Diseases
Synthesis of N-glyoxyl prolyl and pipecolyl amides and thioesters and evaluation of their in vitro and in vivo nerve regenerative effects.
Neurodegenerative Diseases
The intracellular domain of amyloid precursor protein interacts with FKBP12.
Neurodegenerative Diseases
The specific FKBP38 inhibitor N-(N',N'-dimethylcarboxamidomethyl)cycloheximide has potent neuroprotective and neurotrophic properties in brain ischemia.
Neuroinflammatory Diseases
Glucocorticoids: Dr. Jekyll and Mr. Hyde of Hippocampal Neuroinflammation.
Neuroinflammatory Diseases
Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis.
Neutropenia
Successful mammalian target of rapamycin inhibitor maintenance therapy following induction chemotherapy with gemcitabine and doxorubicin for metastatic sarcomatoid renal cell carcinoma.
Newcastle Disease
Glucocorticoids modulate NF-kappaB-dependent gene expression by up-regulating FKBP51 expression in Newcastle disease virus-infected chickens.
Newcastle Disease
Mitochondria-nucleus shuttling FK506-binding protein 51 interacts with TRAF proteins and facilitates the RIG-I-like receptor-mediated expression of type I IFN.
Non-alcoholic Fatty Liver Disease
Cyclophilin inhibition as a potential treatment for nonalcoholic steatohepatitis (NASH).
Non-alcoholic Fatty Liver Disease
Elevated Serum Cyclophilin D Level is Associated with Nonalcoholic Fatty Liver Disease and Higher Fibrosis Scores in Patients with Diabetes Mellitus.
Non-alcoholic Fatty Liver Disease
Serum concentrations of Cyclophilin A in patients with Nonalcoholic Fatty Liver Disease.
Obesity
Bark of Passiflora edulis Treatment Stimulates Antioxidant Capacity, and Reduces Dyslipidemia and Body Fat in db/db Mice.
Obesity
Enhancement of anxiety, facilitation of avoidance behavior, and occurrence of adult-onset obesity in mice lacking mitochondrial cyclophilin D.
Obesity
FKBP51 controls cellular adipogenesis through p38 kinase-mediated phosphorylation of GR? and PPAR?.
Obesity
FKBP51 Null Mice Are Resistant to Diet-Induced Obesity and the PPAR? Agonist Rosiglitazone.
Obesity
Hypothalamic Fkbp51 is induced by fasting and elevated hypothalamic expression promotes obese phenotypes.
Obesity
Interplay between diet-induced obesity and chronic stress in mice: potential role of FKBP51.
Obesity
Loss of FKBP5 impedes adipocyte differentiation under both normoxia and hypoxic stress.
Obesity
Mechanisms of oleic acid deterioration in insulin secretion: role in the pathogenesis of type 2 diabetes.
Obesity
Pediatric Obesity-A Potential Risk Factor for Systemic Inflammatory Syndrome Associated to COVID-19, a Case Report.
Optic Atrophy, Autosomal Dominant
The mitochondrial permeability transition regulates cytochrome c release for apoptosis during endoplasmic reticulum stress by remodeling the cristae junction.
Oral Submucous Fibrosis
Cyclophilin A was revealed as a candidate marker for human oral submucous fibrosis by proteomic analysis.
Oral Submucous Fibrosis
Proteomic identification of cyclophilin A as a potential biomarker and therapeutic target in oral submucous fibrosis.
Osteoarthritis, Knee
Presence of cyclophilin A in synovial fluids of patients with rheumatoid arthritis.
Osteoarthritis, Knee
The trajectories of depression symptoms and comorbidity in knee osteoarthritis subjects.
Osteogenesis Imperfecta
A novel splicing mutation in FKBP10 causing osteogenesis imperfecta with a possible mineralization defect.
Osteogenesis Imperfecta
A substrate preference for the rough endoplasmic reticulum resident protein FKBP22 during collagen biosynthesis.
Osteogenesis Imperfecta
Abnormal type I collagen post-translational modification and crosslinking in a cyclophilin B KO mouse model of recessive osteogenesis imperfecta.
Osteogenesis Imperfecta
Absence of FKBP10 in recessive type XI osteogenesis imperfecta leads to diminished collagen cross-linking and reduced collagen deposition in extracellular matrix.
Osteogenesis Imperfecta
Analysis of FKBP10, SERPINH1, and SERPINF1 genes in patients with osteogenesis imperfecta.
Osteogenesis Imperfecta
Case Report: Exome Sequencing Identified a Novel Compound Heterozygous Variation in PLOD2 Causing Bruck Syndrome Type 2.
Osteogenesis Imperfecta
Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate.
Osteogenesis Imperfecta
Cyclophilin-B modulates collagen cross-linking by differentially affecting lysine hydroxylation in the helical and telopeptidyl domains of tendon type I collagen.
Osteogenesis Imperfecta
Endoplasmic reticulum stress or mutation of an EF-hand Ca(2+)-binding domain directs the FKBP65 rotamase to an ERAD-based proteolysis.
Osteogenesis Imperfecta
From Drosophila to Humans: Reflections on the Roles of the Prolyl Isomerases and Chaperones, Cyclophilins, in Cell Function and Disease.
Osteogenesis Imperfecta
Homozygous sequence variants in the FKBP10 gene underlie osteogenesis imperfecta in consanguineous families.
Osteogenesis Imperfecta
Kuskokwim Syndrome, a Recessive Congenital Contracture Disorder, Extends the Phenotype of FKBP10? Mutations.
Osteogenesis Imperfecta
Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding.
Osteogenesis Imperfecta
Localized chondro-ossification underlies joint dysfunction and motor deficits in the Fkbp10 mouse model of osteogenesis imperfecta.
Osteogenesis Imperfecta
Long-Term Follow-Up Outcomes of 19 Patients with Osteogenesis Imperfecta Type XI and Bruck Syndrome Type I Caused by FKBP10 Variants.
Osteogenesis Imperfecta
Mutations in FKBP10 can cause a severe form of isolated Osteogenesis imperfecta.
Osteogenesis Imperfecta
Mutations in FKBP10 cause both Bruck syndrome and isolated osteogenesis imperfecta in humans.
Osteogenesis Imperfecta
Mutations in FKBP10 cause recessive osteogenesis imperfecta and type 1 bruck syndrome.
Osteogenesis Imperfecta
Mutations in FKBP10, which result in Bruck syndrome and recessive forms of osteogenesis imperfecta, inhibit the hydroxylation of telopeptide lysines in bone collagen.
Osteogenesis Imperfecta
Mutations in PLOD2 cause autosomal-recessive connective tissue disorders within the Bruck syndrome-Osteogenesis imperfecta phenotypic spectrum.
Osteogenesis Imperfecta
Mutations in PPIB (cyclophilin B) delay type I procollagen chain association and result in perinatal lethal to moderate osteogenesis imperfecta phenotypes.
Osteogenesis Imperfecta
Mutations in the gene encoding the RER protein FKBP65 cause autosomal-recessive osteogenesis imperfecta.
Osteogenesis Imperfecta
Mutations in the Gene Encoding the RER Protein FKBP65 Cause Autosomal-Recessive Osteogenesis Imperfecta.
Osteogenesis Imperfecta
Novel Deletion of SERPINF1 Causes Autosomal Recessive Osteogenesis Imperfecta Type VI in Two Brazilian Families.
Osteogenesis Imperfecta
Novel FKBP10 Mutation in a Patient with Osteogenesis Imperfecta Type XI.
Osteogenesis Imperfecta
Novel mutation of FKBP10 in a pediatric patient with osteogenesis imperfecta type XI identified by clinical exome sequencing.
Osteogenesis Imperfecta
Novel mutations in FKBP10 in Chinese patients with osteogenesis imperfecta and their treatment with zoledronic acid.
Osteogenesis Imperfecta
Novel mutations of the SERPINF1 and FKBP10 genes in Chinese families with autosomal recessive osteogenesis imperfecta.
Osteogenesis Imperfecta
Osteogenesis imperfecta type 3 in South Africa: Causative mutations in FKBP10.
Osteogenesis Imperfecta
Osteogenesis imperfecta, normal collagen folding, and lack of cyclophilin B.
Osteogenesis Imperfecta
Splicing defect in FKBP10 gene causes autosomal recessive osteogenesis imperfecta disease: a case report.
Osteogenesis Imperfecta
The identification of novel mutations in COL1A1, COL1A2, and LEPRE1 genes in Chinese patients with osteogenesis imperfecta.
Osteonecrosis
Rituximab as a trigger factor of medication-related osteonecrosis of the jaw. A case report.
Osteoporosis
Bruck syndrome 2 variant lacking congenital contractures and involving a novel compound heterozygous PLOD2 mutation.
Osteoporosis
Cyclophilin D Knock-Out Mice Show Enhanced Resistance to Osteoporosis and to Metabolic Changes Observed in Aging Bone.
Osteoporosis
Identification of novel genes associated with fracture healing in osteoporosis induced by Krm2 overexpression or Lrp5 deficiency.
Osteoporosis, Postmenopausal
PPWD1 is associated with the occurrence of postmenopausal osteoporosis as determined by weighted gene co?expression network analysis.
Osteosarcoma
Anesthesia for euthanasia influences mRNA expression in healthy mice and after traumatic brain injury.
Osteosarcoma
Characterisation of cytosolic FK506 binding protein 12 and its role in modulating expression of Cbfa1 and osterix in ROS 17/2.8 cells.
Osteosarcoma
Identification of valid reference housekeeping genes for gene expression analysis in tumor neovascularization studies.
Otitis Media
Development of antibodies against pneumococcal proteins alpha-enolase, immunoglobulin A1 protease, streptococcal lipoprotein rotamase A, and putative proteinase maturation protein A in relation to pneumococcal carriage and Otitis Media.
Ovarian Cysts
Expression of FK506 binding protein 65 (FKBP65) is decreased in epithelial ovarian cancer cells compared to benign tumor cells and to ovarian epithelium.
Ovarian Neoplasms
Inhibition of ovarian cancer cell growth by a novel TAK1 inhibitor LYTAK1.
Ovarian Neoplasms
Proteomic analysis and identification of new biomarkers and therapeutic targets for invasive ovarian cancer.
Pancreatic Diseases
Bacterial endotoxin: a trigger factor for alcoholic pancreatitis? Evidence from a novel, physiologically relevant animal model.
Pancreatic Neoplasms
Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker.
Pancreatic Neoplasms
Cyclophilin A is overexpressed in human pancreatic cancer cells and stimulates cell proliferation through CD147.
Pancreatic Neoplasms
Cyclophilin B promotes cell proliferation, migration, invasion and angiogenesis via regulating the STAT3 pathway in non-small cell lung cancer.
Pancreatic Neoplasms
Effect of cyclophilin A on gene expression in human pancreatic cancer cells.
Pancreatic Neoplasms
FK506-binding protein 5 inhibits proliferation and stimulates apoptosis of glioma cells.
Pancreatic Neoplasms
FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt.
Pancreatic Neoplasms
Further characterization of the target of a potential aptamer biomarker for pancreatic cancer: cyclophilin B and its posttranslational modifications.
Pancreatic Neoplasms
Gemcitabine-induced pancreatic cancer cell death is associated with MST1/cyclophilin D mitochondrial complexation.
Pancreatic Neoplasms
MiR-30a regulates cancer cell response to chemotherapy through SNAI1/IRS1/AKT pathway.
Pancreatic Neoplasms
Targeting pancreatic cancer cells by a novel hydroxamate-based histone deacetylase (HDAC) inhibitor ST-3595.
Pancreatic Neoplasms
USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51-AKT signaling.
Pancreatitis
Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models.
Pancreatitis
Novel mitochondrial transition pore inhibitor N-methyl-4-isoleucine cyclosporin is a new therapeutic option in acute pancreatitis.
Pancreatitis
Pancreatic acinar cells-derived cyclophilin A promotes pancreatic damage by activating NF-?B pathway in experimental pancreatitis.
Pancreatitis
Predictive value of serum cyclophilin A concentrations after acute pancreatitis.
Pancreatitis
Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry.
Pancreatitis
Small Molecule Inhibitors of Cyclophilin D To Protect Mitochondrial Function as a Potential Treatment for Acute Pancreatitis.
Pancreatitis, Alcoholic
Bacterial endotoxin: a trigger factor for alcoholic pancreatitis? Evidence from a novel, physiologically relevant animal model.
Papilloma
Retromolar trigone--oropharynx junction maligns tumor surgery: transmandibular versus oral approach.
Paralysis
Acute Ascending Flaccid Paralysis Secondary to Multiple Trigger Factor Induced Hyperkalemia.
Paralysis
Analysis of reference gene stability after Israeli acute paralysis virus infection in bumblebees Bombus terrestris.
Parasitemia
Comparison of a rapid field immunochromatographic test to expert microscopy for the detection of Plasmodium falciparum asexual parasitemia in Thailand.
Parasitemia
High Frequency of Blackwater Fever Among Children Presenting to Hospital With Severe Febrile Illnesses in Eastern Uganda.
Parasitic Diseases
Immunization with the Leishmania infantum recombinant cyclophilin protein 1 confers partial protection to subsequent parasite infection and generates specific memory T cells.
Parkinson Disease
Comparative Analysis of Different Peptidyl-Prolyl Isomerases Reveals FK506-binding Protein 12 as the Most Potent Enhancer of {alpha}-Synuclein Aggregation.
Parkinson Disease
Failure of GPI compounds to display neurotrophic activity in vitro and in vivo.
Parkinson Disease
Increased Striatal mRNA and Protein Levels of the Immunophilin FKBP-12 in Experimental Parkinson's Disease and Identification of FKBP-12-Binding Proteins.
Parkinson Disease
Mitochondrial Permeability Transition Pore Component Cyclophilin D Distinguishes Nigrostriatal Dopaminergic Death Paradigms in the MPTP Mouse Model of Parkinson's Disease.
Parkinson Disease
Pathological gambling from dopamine agonist and deep brain stimulation of the nucleus tegmenti pedunculopontine.
Parkinson Disease
Small family with key contacts: par14 and par17 parvulin proteins, relatives of pin1, now emerge in biomedical research.
Parkinson Disease
The Molecular Basis of the Interaction of Cyclophilin?A with ?-Synuclein.
Parkinson Disease
The P66Shc/mitochondrial permeability transition pore pathway determines neurodegeneration.
Parkinson Disease
The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease.
Pemphigoid, Bullous
Radiation therapy as a trigger factor for initially localized bullous pemphigoid.
Pemphigus
Pemphigus: a complex T cell-dependent autoimmune disorder leading to acantholysis.
peptidylprolyl isomerase deficiency
Altered excitation-contraction coupling with skeletal muscle specific FKBP12 deficiency.
peptidylprolyl isomerase deficiency
Cyclophilin B Deficiency Causes Abnormal Dentin Collagen Matrix.
peptidylprolyl isomerase deficiency
FK506 binding protein 12 deficiency in endothelial and hematopoietic cells decreases regulatory T cells and causes hypertension.
peptidylprolyl isomerase deficiency
FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis.
peptidylprolyl isomerase deficiency
FKBP12 deficiency reduces strength deficits after eccentric contraction-induced muscle injury.
peptidylprolyl isomerase deficiency
FKBP51 reciprocally regulates GR? and PPAR? activation via the Akt-p38 pathway.
peptidylprolyl isomerase deficiency
FKBP65-dependent peptidyl-prolyl isomerase activity potentiates the lysyl hydroxylase 2-driven collagen cross-link switch.
peptidylprolyl isomerase deficiency
HSP47 and FKBP65 cooperate in the synthesis of type I procollagen.
peptidylprolyl isomerase deficiency
Ligands for FKBP12 increase Ca2+ influx and protein synthesis to improve skeletal muscle function.
peptidylprolyl isomerase deficiency
Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior.
peptidylprolyl isomerase deficiency
Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.
peptidylprolyl isomerase deficiency
Uterine FK506-binding protein 52 (FKBP52)-peroxiredoxin-6 (PRDX6) signaling protects pregnancy from overt oxidative stress.
Pericoronitis
Gingival Reactive Lesions in Orally Rehabilitated Patients by Free Revascularized Flap.
Periodontal Diseases
Evaluation of gingival crevicular fluid cyclophilin a and extracellular matrix metalloproteinase inducer levels in different periodontal diseases.
Periodontal Diseases
PIN1 inhibition suppresses osteoclast differentiation and inflammatory responses.
Periodontal Diseases
Radiologic bone loss in patients with bisphosphonate-associated osteonecrosis of the jaws: a case-control study.
Periodontal Diseases
Study of the participation of MMP-7, EMMPRIN and cyclophilin A in the pathogenesis of periodontal disease.
Periodontitis
Cyclophilin A (CypA) is associated with the inflammatory infiltration and alveolar bone destruction in an experimental periodontitis.
Periodontitis
EMMPRIN-CypA contributes to the inflammatory processes in human periodontitis through infiltrating CD68+ inflammatory cells.
Peripheral Arterial Disease
Cyclophilin A is associated with peripheral artery disease and chronic kidney disease in geriatrics: The Tianliao Old People (TOP) study.
Persistent Infection
Interstitial lung fibrosis and rheumatic disorders in patients with hepatitis C virus infection.
Peste-des-Petits-Ruminants
Peste des petits ruminants virus hemagglutinin (H) induces lysosomal degradation of host cyclophilin A to facilitate viral replication.
Pharyngitis
An Experimental Group A Streptococcus Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model.
Pituitary Neoplasms
Acute manifestation of LHON and coincidental finding of a pituitary adenoma: a case report.
Plasmacytoma
Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene.
Plasmacytoma
The Function of FK506-Binding Protein 13 in Protein Quality Control Protects Plasma Cells from Endoplasmic Reticulum Stress-Associated Apoptosis.
Pneumonia
FKBP51 modulates steroid sensitivity and NF?B signalling: A novel anti-inflammatory drug target.
Pneumonia
Structural, biochemical, and in vivo characterization of the first virally encoded cyclophilin from the Mimivirus.
Porcine Reproductive and Respiratory Syndrome
Cyclophilin inhibitors block arterivirus replication by interfering with viral RNA synthesis.
Post-Cardiac Arrest Syndrome
Fast therapeutic hypothermia prevents post-cardiac arrest syndrome through cyclophilin D-mediated mitochondrial permeability transition inhibition.
Pouchitis
FK506-Binding Protein 5 mRNA Levels in Ileal Mucosa Are Associated with Pouchitis in Patients with Ulcerative Colitis.
Pre-Eclampsia
Association between polymorphism in Cyclophilin A gene and its serum and placental expression in Han Chinese women with severe preeclampsia.
Pre-Eclampsia
Cyclophilin A inhibits trophoblast migration and invasion in vitro and vivo through p38/ERK/JNK pathways and causes features of preeclampsia in mice.
Pre-Eclampsia
Expression of 52-kDa FK506-binding protein (FKBP52) in human placenta complicated by preeclampsia and intrauterine growth restriction.
Pre-Eclampsia
Maternal and cord blood cyclophilin A in severe preeclampsia and normal pregnancy and its correlation with vitamin D and zinc.
Pre-Eclampsia
Predictive value of early second trimester maternal serum cyclophilin A concentrations in women complicated with preeclampsia: a preliminary case-control study.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
FK506 binding proteins as targets in anticancer therapy.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Raised Expression of APRIL in Chinese Children With Acute Lymphoblastic Leukemia and its Clinical Implications.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Tamoxifen Sensitizes Acute Lymphoblastic Leukemia Cells to Cannabidiol by Targeting Cyclophilin-D and Altering Mitochondrial Ca2+ Homeostasis.
Premature Birth
Dynamic Changes in DNA Methylation Occur during the First Year of Life in Preterm Infants.
Primary Myelofibrosis
Overexpression of FKBP51 in idiopathic myelofibrosis regulates the growth factor independence of megakaryocyte progenitors.
Primary Myelofibrosis
Spontaneous STAT5 activation induces growth factor independence in idiopathic myelofibrosis: possible relationship with FKBP51 overexpression.
Prion Diseases
Effects of peptidyl-prolyl isomerase 1 depletion in animal models of prion diseases.
Prion Diseases
Inhibition of the FKBP family of peptidyl prolyl isomerases induces abortive translocation and degradation of the cellular prion protein.
Proctocolitis
Neuroimaging of Takayasu Arteritis in a Patient with Ulcerative Rectocolitis.
Prolactinoma
PGAM5-CypD pathway is involved in bromocriptine-induced RIP3/MLKL-dependent necroptosis of prolactinoma cells.
Prostatic Neoplasms
A proteome study of secreted prostatic factors affecting osteoblastic activity: identification and characterisation of cyclophilin A.
Prostatic Neoplasms
Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction.
Prostatic Neoplasms
Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer.
Prostatic Neoplasms
Association of Remitting Seronegative Symmetrical Synovitis with Pitting Edema, Polymyalgia Rheumatica, and Adenocarcinoma of the Prostate.
Prostatic Neoplasms
Binding modes and conformational changes of FK506-binding protein 51 induced by inhibitor bindings: insight into molecular mechanisms based on multiple simulation technologies.
Prostatic Neoplasms
Bioanalytical Assay Development and Validation for the Pharmacokinetic Study of GMC1, a Novel FKBP52 Co-chaperone Inhibitor for Castration Resistant Prostate Cancer.
Prostatic Neoplasms
FKBP51 and Cyp40 are positive regulators of androgen-dependent prostate cancer cell growth and the targets of FK506 and cyclosporin A.
Prostatic Neoplasms
FKBP51 and FKBP52 regulate androgen receptor dimerization and proliferation in prostate cancer cells.
Prostatic Neoplasms
FKBP51 promotes assembly of the Hsp90 chaperone complex and regulates androgen receptor signaling in prostate cancer cells.
Prostatic Neoplasms
Histone H2B ubiquitin ligases RNF20 and RNF40 in androgen signaling and prostate cancer cell growth.
Prostatic Neoplasms
Identification and validation of novel androgen-regulated genes in prostate cancer.
Prostatic Neoplasms
Inactivation of ID4 promotes a CRPC phenotype with constitutive AR activation through FKBP52.
Prostatic Neoplasms
Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers.
Prostatic Neoplasms
Molecular dynamics simulations of site point mutations in the TPR domain of cyclophilin 40 identify conformational states with distinct dynamic and enzymatic properties.
Prostatic Neoplasms
Pin1 inhibition improves the efficacy of ralaniten compounds that bind to the N-terminal domain of androgen receptor.
Prostatic Neoplasms
Prostaglandin 15d-PGJ(2) inhibits androgen receptor signaling in prostate cancer cells.
Prostatic Neoplasms
Rapamycin inhibits AR signaling pathway in prostate cancer by interacting with the FK1 domain of FKBP51.
Prostatic Neoplasms
Re: targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells.
Prostatic Neoplasms
Regulation of eIF4F Translation Initiation Complex by the Peptidyl Prolyl Isomerase FKBP7 in Taxane-resistant Prostate Cancer.
Prostatic Neoplasms
Restoration of FKBP51 protein promotes the progression of castration resistant prostate cancer.
Prostatic Neoplasms
Solution formulation development and efficacy of MJC13 in a preclinical model of castration-resistant prostate cancer.
Prostatic Neoplasms
Synthesis of novel S-linked dihydroartemisinin derivatives and evaluation of their anticancer activity.
Prostatic Neoplasms
Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells.
Prostatic Neoplasms
The FKBP52 Cochaperone Acts in Synergy with ?-Catenin to Potentiate Androgen Receptor Signaling.
Prostatic Neoplasms
The immunophilin ligands cyclosporin A and FK506 suppress prostate cancer cell growth by androgen receptor-dependent and -independent mechanisms.
Prostatic Neoplasms
The prognostic value of stromal FK506-binding protein 1 and androgen receptor in prostate cancer outcome.
Prostatic Neoplasms
The prolyl isomerase pin1 regulates mRNA levels of genes with short half-lives by targeting specific RNA binding proteins.
Prostatic Neoplasms
Words of wisdom. Re: Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells.
protein acetyllysine n-acetyltransferase deficiency
Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges.
Psoriasis
Distribution of Malassezia species in patients with psoriasis and healthy individuals in Tehran, Iran.
Psoriasis
Low serum testosterone levels in male psoriasis patients correlate with disease severity.
Psoriasis
Smoking does not Alter the Therapy Response to Systemic Anti-psoriatic Therapies: A Two-country, Multi-centre, Prospective, Non-interventional Study.
Psoriasis
The associations between psychological stress and psoriasis: a systematic review.
Puberty, Precocious
Precocious puberty and empty sella syndrome in a girl cured of acute lymphoblastic leukemia.
Pulmonary Arterial Hypertension
Endothelial-to-Mesenchymal Transition and Inflammation Play Key Roles in Cyclophilin A-Induced Pulmonary Arterial Hypertension.
Pulmonary Arterial Hypertension
The effect of honokiol on pulmonary artery endothelium cell autophagy mediated by cyclophilin A in hypoxic pulmonary arterial hypertension.
Pulmonary Disease, Chronic Obstructive
Evaluation of glucocorticoid receptor function in COPD lung macrophages using beclomethasone-17-monopropionate.
Pulmonary Disease, Chronic Obstructive
Heat shock protein 27 and cyclophilin A associate with the pathogenesis of COPD.
Pulmonary Disease, Chronic Obstructive
Increased FKBP51 in induced sputum cells of chronic obstructive pulmonary disease patients after therapy.
Pulmonary Disease, Chronic Obstructive
The clinical implication of serum cyclophilin A in patients with chronic obstructive pulmonary disease.
Pulmonary Embolism
Inhibition of the cyclophilin A-CD147 interaction attenuates right ventricular injury and dysfunction after acute pulmonary embolism in rats.
Pulmonary Embolism
Therapeutic effect of SP-8356 on pulmonary embolism-associated cardiac injury is mediated by its ability to suppress apoptosis and inflammation.
Pulmonary Embolism
[Recommendations for the Use of Indirect and Direct Anticoagulants for Long-Term Prophylaxis after Venous Thromboembolism].
Pulmonary Embolism
[Thrombophilic conditions in the pathogenesis of venous thromboembolism]
Pulmonary Fibrosis
Developmental regulation and coordinate reexpression of FKBP65 with extracellular matrix proteins after lung injury suggest a specialized function for this endoplasmic reticulum immunophilin.
Pulmonary Fibrosis
FK506-Binding Protein 13 Expression Is Upregulated in Interstitial Lung Disease and Correlated with Clinical Severity. A Potentially Protective Role.
Purpura, Thrombocytopenic, Idiopathic
FK506-binding protein 51 (FKBP5) gene polymorphism is not associated with glucocorticoid therapy outcome in patients with idiopathic thrombocytopenic purpura.
Q Fever
Antibodies are generated during infection to Coxiella burnetii macrophage infectivity potentiator protein (Cb-Mip).
Q Fever
Molecular cloning of a Coxiella burnetii gene encoding a macrophage infectivity potentiator (Mip) analogue.
Q Fever
Relationship between pathogenicity of Coxiella burnetii isolates and gene sequences of the macrophage infectivity potentiator (Cbmip) and sensor-like protein (qrsA).
Renal Insufficiency
Molecular cloning of a complementary DNA to rat cyclophilin-like protein mRNA.
Renal Insufficiency, Chronic
Cyclophilin A is associated with peripheral artery disease and chronic kidney disease in geriatrics: The Tianliao Old People (TOP) study.
Renal Insufficiency, Chronic
Cyclophilin Inhibition Protects Against Experimental Acute Kidney Injury and Renal Interstitial Fibrosis.
Renal Insufficiency, Chronic
The Role of Peptidyl Prolyl Isomerases in Aging and Vascular Diseases.
Reperfusion Injury
A Phenyl-Pyrrolidine Derivative Reveals a Dual Inhibition Mechanism of Myocardial Mitochondrial Permeability Transition Pore, Which Is Limited by Its Myocardial Distribution.
Reperfusion Injury
Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys.
Reperfusion Injury
Cyclophilin D and myocardial ischemia-reperfusion injury: a fresh perspective.
Reperfusion Injury
Divergent Effects of Cyclophilin-D Inhibition on the Female Rat Heart: Acute Versus Chronic Post-Myocardial Infarction.
Reperfusion Injury
Endoplasmic reticulum stress contributes to heart protection induced by cyclophilin D inhibition.
Reperfusion Injury
Mitochondrial cyclophilin-D as a potential therapeutic target for post-myocardial infarction heart failure.
Reperfusion Injury
Mitochondrial permeability transition in cardiac ischemia-reperfusion: whether cyclophilin D is a viable target for cardioprotection?
Reperfusion Injury
Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A.
Reperfusion Injury
Simultaneous targeting of mitochondria and monocytes enhances neuroprotection against ischemia-reperfusion injury.
Reproductive Tract Infections
Vaccination with MIP or Pgp3 induces cross-serovar protection against chlamydial genital tract infection in mice.
Respiratory Insufficiency
First case of atypical takotsubo cardiomyopathy in a bilateral lung-transplanted patient due to acute respiratory failure.
Respiratory Insufficiency
The divergent ventilatory and heart rate response to moderate hypercapnia in infants with apnoea of infancy.
Respiratory Tract Infections
Home exposure to Arabian incense (bakhour) and asthma symptoms in children: a community survey in two regions in Oman.
Respiratory Tract Infections
Rapid-onset asthma attack: a prospective cohort study about characteristics and response to emergency department treatment.
Retinal Degeneration
Expanding the clinical and molecular spectrum of the CWC27-related spliceosomopathy.
Retinal Degeneration
Mutations in the Spliceosome Component CWC27 Cause Retinal Degeneration with or without Additional Developmental Anomalies.
Retinal Degeneration
Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.
Retinoblastoma
A locking mechanism regulates RNA synthesis and host protein interaction by the hepatitis C virus polymerase.
Retinoblastoma
Interaction of the retinoblastoma gene product, RB, with cyclophilin A negatively affects cyclosporin-inhibited NFAT signaling.
Retinoblastoma
Separation and identification of differentially expressed nuclear matrix proteins between human esophageal immortalized and carcinomatous cell lines.
Retroviridae Infections
The ability of multimerized cyclophilin A to restrict retrovirus infection.
Rhinitis
[Environmental control for allergic diseases--avoiding and killing effect on housedust-mite by eastern red cedar]
Root Caries
Concentration dependence of quaternary ammonium monomer on the design of high-performance bioactive composite for root caries restorations.
Rotavirus Infections
Proteomic methods reveal cyclophilin a function as a host restriction factor against rotavirus infection.
Sarcoma
Identification and Validation of Housekeeping Genes for Gene Expression Analysis of Cancer Stem Cells.
Sarcoma
The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells.
Sarcoma 37
Subcellular distribution of inorganic pyrophosphatase activity in various normal and neoplastic cell types.
Sarcoma, Avian
Effect of multimerization on membrane association of Rous sarcoma virus and HIV-1 matrix domain proteins.
Schistosomiasis
Identification and characterization of Schistosoma mansoni p17.7, a cyclophilin.
Schistosomiasis
The Schistosoma mansoni cyclophilin A epitope 107-121 induces a protective immune response against schistosomiasis.
Sciatic Neuropathy
Neuronal regeneration enhances the expression of the immunophilin FKBP-12.
Scleroderma, Localized
Chronic venous insufficiency - a potential trigger for localized scleroderma.
Seizures
Acute Intermittent Porphyria - an Unexpected Association in a Patient with Newly Diagnosed Crohn's Disease.
Seizures
Effects of repeated injection of cyclosporin A on pentylenetetrazol-induced convulsion and cyclophilin mRNA levels in rat brain.
Seizures
Energy drinks as a trigger factor for seizures in paediatric patients: A case report.
Seizures
Lateral hypothalamus orexinergic system modulates the stress effect on pentylenetetrazol induced seizures through corticotropin releasing hormone receptor type 1.
Sepsis
Acute Intermittent Porphyria - an Unexpected Association in a Patient with Newly Diagnosed Crohn's Disease.
Sepsis
Clonorchis sinensis cyclophilin A immunization protected mice from CLP-induced sepsis.
Sepsis
Lack of cyclophilin D protects against the development of acute lung injury in endotoxemia.
Sepsis
Prognosis of sepsis induced by cecal ligation and puncture in mice improved by anti-Clonorchis Sinensis cyclopholin a antibodies.
Sepsis
[Association between peripheral perfusion, microcirculation and mortality in sepsis: a systematic review].
Sepsis-Associated Encephalopathy
Regulation of Sirtuin 3-Mediated Deacetylation of Cyclophilin D Attenuated Cognitive Dysfunction Induced by Sepsis-Associated Encephalopathy in Mice.
Severe Acute Respiratory Syndrome
Function of HAb18G/CD147 in invasion of host cells by severe acute respiratory syndrome coronavirus.
Severe Combined Immunodeficiency
Identification and genetic mapping of the mouse Fkbp9 gene encoding a new member of FK506-binding protein family.
Shock, Septic
INF/IR-3: CYCLOPHILIN D DEPENDENT MPT AMPLIFIES INFLAMMATORY RESPONSE IN SEPTIC SHOCK.
Shock, Septic
Staphylococcus aureus-superantigen decreases FKBP51 mRNA expression and cell-response to suppressive efficacy of a glucocorticoid in human peripheral blood mononuclear cells: possible implication of mitogen-activated protein kinase pathways.
Sigmoid Neoplasms
Takotsubo Cardiomyopathy in a Patient with Undiscovered Sigmoid Colon Cancer.
Sinus Thrombosis, Intracranial
Superior sagittal sinus dural arteriovenous fistula caused by treatment of meningioma masquerades as sinus thrombosis.
Skin Diseases
IL-18 skews the invariant NKT-cell population via autoreactive activation in atopic eczema.
Skin Neoplasms
Investigation of skin self-examination and sunscreen use in adolescents in northern Cyprus.
Skin Neoplasms
Surgery combined with local 5-aminolevulinic acid-photodynamic therapy on skin cancer and its effect on the expression of cyclophilin A, cyclophilin B and CD147.
Sleep Deprivation
Deficiency of FK506-binding protein (FKBP) 51 alters sleep architecture and recovery sleep responses to stress in mice.
Sleep Initiation and Maintenance Disorders
Evaluation of the Etiology, Clinical Presentation, Findings and Prophylaxis of Children with Headache.
Sleep Wake Disorders
Deficiency of FK506-binding protein (FKBP) 51 alters sleep architecture and recovery sleep responses to stress in mice.
Small Cell Lung Carcinoma
Cyclophilin A is upregulated in small cell lung cancer and activates ERK1/2 signal.
Small Cell Lung Carcinoma
[Clinical significance of oncogene product expression in human lung cancer]
Spastic Paraplegia, Hereditary
Hereditary spastic paraplegia protein spartin is an FK506-binding protein identified by mRNA display.
Squamous Cell Carcinoma of Head and Neck
CD147 promotes invasion and MMP-9 expression through MEK signaling and predicts poor prognosis in hypopharyngeal squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Cyclophilin A-EMMPRIN interaction induces invasion of head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
The rotamase Pin1 is up-regulated, hypophosphorylated and required for cell cycle progression in head and neck squamous cell carcinomas.
Squamous Cell Carcinoma of Head and Neck
[Expression of cyclophilin A in oral squamous cell carcinoma and its effect on cell proliferation and invasion].
ST Elevation Myocardial Infarction
Decrease in plasma cyclophilin A concentration at 1 month after myocardial infarction predicts better left ventricular performance and synchronicity at 6 months: a pilot study in patients with ST elevation myocardial infarction.
ST Elevation Myocardial Infarction
The Emergency Medical Care of Patients With Acute Myocardial Infarction.
Starvation
Cyclophilin and trigger factor from Bacillus subtilis catalyze in vitro protein folding and are necessary for viability under starvation conditions.
Starvation
Evaluation and validation of experimental condition-specific reference genes for normalization of gene expression in Asia II-I Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae).
Stomach Diseases
Subcellular and functional proteomic analysis of the cellular responses induced by Helicobacter pylori.
Stomach Neoplasms
Comprehensive evaluation of FKBP10 expression and its prognostic potential in gastric cancer.
Stomach Neoplasms
Cyclophilin A Enhances Cell Proliferation and Xenografted Tumor Growth of Early Gastric Cancer.
Stomach Neoplasms
Esculetin induces apoptosis in human gastric cancer cells through a cyclophilin D-mediated mitochondrial permeability transition pore associated with ROS.
Stomach Neoplasms
FKBP10 Acts as a New Biomarker for Prognosis and Lymph Node Metastasis of Gastric Cancer by Bioinformatics Analysis and in Vitro Experiments.
Stomach Neoplasms
FKBP10 functioned as a cancer-promoting factor mediates cell proliferation, invasion, and migration via regulating PI3K signaling pathway in stomach adenocarcinoma.
Stomach Neoplasms
Gastric Cancer Cell Proliferation and Survival Is Enabled by a Cyclophilin B/STAT3/miR-520d-5p Signaling Feedback Loop.
Stomach Neoplasms
Helicobacter pylori FKBP-type PPIase promotes gastric epithelial cell proliferation and anchorage-independent growth through activation of ERK-mediated mitogenic signaling pathway.
Stomach Neoplasms
Identification of Cyclophilin A as a Potential Anticancer Target of Novel Nargenicin A1 Analog in AGS Gastric Cancer Cells.
Stomach Neoplasms
Subtractive hybridization analysis of gastric diseases-associated Helicobacter pylori identifies peptidyl-prolyl isomerase as a potential marker for gastric cancer.
Stomach Neoplasms
Zerumbone induces gastric cancer cells apoptosis: Involving cyclophilin A.
Strabismus
Binding of the cyclophilin 40 ortholog SQUINT to Hsp90 protein is required for SQUINT function in Arabidopsis.
Streptococcal Infections
Erythema elevatum diutinum and HIV infection: a report of five cases.
Stroke
Cyclophilin A: A Predictive Biomarker of Carotid Stenosis in Cerebral Ischemic Stroke.
Stroke
Novel proteins associated with risk for coronary heart disease or stroke among postmenopausal women identified by in-depth plasma proteome profiling.
Stroke
SP-8356, a Novel Inhibitor of CD147-Cyclophilin A Interactions, Reduces Plaque Progression and Stabilizes Vulnerable Plaques in apoE-Deficient Mice.
Subarachnoid Hemorrhage
Altered expression and function of ryanodine receptors and FKBP12.6 after subarachnoid hemorrhage: more than meets the eye.
Subarachnoid Hemorrhage
Cyclophilin a signaling induces pericyte-associated blood-brain barrier disruption after subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Cyclophilin A/Cluster of Differentiation 147 Interactions and Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage.
Subarachnoid Hemorrhage
Cyclophilin A/Cluster of Differentiation 147 Interactions Participate in Early Brain Injury After Subarachnoid Hemorrhage in Rats.
Syncope, Vasovagal
Children with transient loss of consciousness: Clinical characteristics and the effectiveness of diagnostic tests.
Synovitis
Inhibition of synovitis and joint destruction by a new single domain antibody specific for cyclophilin A in two different mouse models of rheumatoid arthritis.
Syphilis
Identification of homologs for thioredoxin, peptidyl prolyl cis-trans isomerase, and glycerophosphodiester phosphodiesterase in outer membrane fractions from Treponema pallidum, the syphilis spirochete.
Systemic Vasculitis
Microscopic polyangiitis following recurrent Staphylococcus aureus bacteremia and infectious endocarditis.
Tachycardia
Preconditioning tachycardia decreases the activity of the mitochondrial permeability transition pore in the dog heart.
Tachycardia, Ventricular
ATP interacts with the CPVT mutation-associated central domain of the cardiac ryanodine receptor.
Takotsubo Cardiomyopathy
First case of atypical takotsubo cardiomyopathy in a bilateral lung-transplanted patient due to acute respiratory failure.
Takotsubo Cardiomyopathy
Trigger factors in takotsubo syndrome - A systematic review of case reports.
Tauopathies
Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.
Tauopathies
Decrease of the Immunophilin FKBP52 Accumulation in Human Brains of Alzheimer's Disease and FTDP-17.
Tauopathies
Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy.
Telangiectasis
Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling.
Teratocarcinoma
Murine cyclophilin-S1: a variant peptidyl-prolyl isomerase with a putative signal sequence expressed in differentiating F9 cells.
Thromboinflammation
Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation.
Thrombophilia
Management of Acute Mesenteric Venous Thrombosis: A Systematic Review of Contemporary Studies.
Thrombophilia
Portal vein thrombosis after variceal endoscopic sclerotherapy in cirrhotic patients: role of genetic thrombophilia.
Thrombosis
Critical role for the mitochondrial permeability transition pore and cyclophilin D in platelet activation and thrombosis.
Thrombosis
Extracellular Cyclophilin A Activates Platelets Via EMMPRIN (CD147) and PI3K/Akt Signaling, Which Promotes Platelet Adhesion and Thrombus Formation In Vitro and In Vivo.
Thrombosis
Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation.
Thrombosis
Functional cyclophilin D moderates platelet adhesion, but enhances the lytic resistance of fibrin.
Thrombosis
Intracellular cyclophilin A is an important Ca2+ regulator in platelets and critically involved in arterial thrombus formation.
Thrombosis
Neutrophil macroaggregates promote widespread pulmonary thrombosis after gut ischemia.
Thrombosis
Portal vein thrombosis after variceal endoscopic sclerotherapy in cirrhotic patients: role of genetic thrombophilia.
Thrombosis
[Proteomic analysis on portal vein tumor thrombus-associated proteins for hepatocellular carcinoma]
Thrombosis
[Recommendations for the Use of Indirect and Direct Anticoagulants for Long-Term Prophylaxis after Venous Thromboembolism].
Thymoma
Cyclophilin A produced by thymocytes regulates the migration of murine bone marrow cells.
Thyroid Cancer, Papillary
FK506-binding protein 5 promotes the progression of papillary thyroid carcinoma.
Thyroid Cancer, Papillary
FKBP51 promotes migration and invasion of papillary thyroid carcinoma through NF-?B-dependent epithelial-to-mesenchymal transition.
Thyroid Diseases
Evidence of association between FKBP1B and thyroid autoimmune disorders in a large Tunisian family.
Toxocariasis
[Investigation of the presence of autoantibodies in patients with toxocariasis]
Trypanosomiasis, African
(1)H, (15)N and (13)C assignments of a putative peptidyl prolyl cis-trans isomerase FKBP12 from Trypanosoma brucei.
Tuberculosis
Backbone and side chain 1H, 15N and 13C assignments of a putative peptidyl prolyl cis-trans isomerase FKBP12 from Mycobacterium tuberculosis.
Tuberculosis
Discovery of allosteric and selective inhibitors of inorganic pyrophosphatase from Mycobacterium tuberculosis.
Tuberculosis
Mitochondrial cyclophilin D regulates T cell metabolic responses and disease tolerance to tuberculosis.
Tuberculosis
Mycobacterium tuberculosis cyclophilin A uses novel signal sequence for secretion and mimics eukaryotic cyclophilins for interaction with host protein repertoire.
Tuberculosis
Mycobacterium tuberculosis Peptidyl-Prolyl Isomerases Are Immunogenic, Alter Cytokine Profile and Aid in Intracellular Survival.
Tuberculosis
Structural and computational dissection of the catalytic mechanism of the inorganic pyrophosphatase from Mycobacterium tuberculosis.
Tuberculosis
Structural insights into the complex of trigger factor chaperone and ribosomal protein S7 from Mycobacterium tuberculosis.
Tuberculosis
TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species.
Tuberculosis
TNF Induces Pathogenic Programmed Macrophage Necrosis in Tuberculosis through a Mitochondrial-Lysosomal-Endoplasmic Reticulum Circuit.
Typhus, Epidemic Louse-Borne
Nucleotide sequence of the gene and features of the major outer membrane protein of a virulent Rickettsia prowazekii strain.
Urethritis
Molecular analysis of two novel Neisseria gonorrhoeae virulent components: the macrophage infectivity potentiator and the outer membrane protein A.
Urinary Bladder Neoplasms
Genome-Wide Association Study of Bladder Cancer in a Chinese Cohort Reveals a New Susceptibility Locus at 5q12.3.
Uterine Cervical Neoplasms
Endoplasmic reticulum vacuolation and unfolded protein response leading to paraptosis like cell death in cyclosporine A treated cancer cervix cells is mediated by cyclophilin B inhibition.
Uterine Cervical Neoplasms
Synthesis and Evaluation of Dibenzothiophene Analogues as Pin1 Inhibitors for Cervical Cancer Therapy.
Uterine Hemorrhage
Progestins Upregulate FKBP51 Expression in Human Endometrial Stromal Cells to Induce Functional Progesterone and Glucocorticoid Withdrawal: Implications for Contraceptive- Associated Abnormal Uterine Bleeding.
Vaccinia
Cyclophillin A (CyPA) is required for efficient HCMV DNA replication and reactivation.
Vaccinia
Redistribution of cyclophilin A to viral factories during vaccinia virus infection and its incorporation into mature particles.
Vascular Calcification
Rho-associated protein kinase and cyclophilin a are involved in inorganic phosphate-induced calcification signaling in vascular smooth muscle cells.
Vascular Diseases
Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus.
Vascular Diseases
Cyclophilin-A: a potential screening marker for vascular disease in type-2 diabetes.
Vascular Diseases
Effects of cyclophilin A on cell proliferation and gene expressions in human vascular smooth muscle cells and endothelial cells.
Vascular Diseases
Peptidyl-prolyl isomerases: functionality and potential therapeutic targets in cardiovascular disease.
Vascular Diseases
Plasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease.
Vascular Diseases
PPIA rs6850: A > G single-nucleotide polymorphism is associated with raised plasma cyclophilin A levels in patients with coronary artery disease.
Vascular Neoplasms
Expression of FKBP12 in benign and malignant vascular endothelium: an immunohistochemical study on conventional sections and tissue microarrays.
Venous Thromboembolism
[Recommendations for the Use of Indirect and Direct Anticoagulants for Long-Term Prophylaxis after Venous Thromboembolism].
Ventilator-Induced Lung Injury
Secreted Extracellular Cyclophilin A Is a Novel Mediator of Ventilator-induced Lung Injury.
Vesicular Stomatitis
Requirement for cyclophilin A for the replication of vesicular stomatitis virus New Jersey serotype.
Viremia
Multiple Mutations in Hepatitis C Virus NS5A Domain II Are Required To Confer a Significant Level of Resistance to Alisporivir.
Virus Diseases
1-(2,6-Dibenzyloxybenzoyl)-3-(9H-fluoren-9-yl)-urea: A novel cyclophilin A allosteric activator.
Virus Diseases
A cyclophilin A (CypA) from Apostichopus japonicus modulates NF-?B translocation as a cofactor.
Virus Diseases
Acetylation regulates cyclophilin A catalysis, immunosuppression and HIV isomerization.
Virus Diseases
Bioengineering and semisynthesis of an optimized cyclophilin inhibitor for treatment of chronic viral infection.
Virus Diseases
Chicken cyclophilin A is an inhibitory factor to influenza virus replication.
Virus Diseases
Curing a viral infection by targeting the host: the example of cyclophilin inhibitors.
Virus Diseases
Cyclophilin A associates with enterovirus-71 virus capsid and plays an essential role in viral infection as an uncoating regulator.
Virus Diseases
Cyclophilin A is an essential cofactor for hepatitis C virus infection and the principal mediator of cyclosporine resistance in vitro.
Virus Diseases
Cyclophilin and viruses: cyclophilin as a cofactor for viral infection and possible anti-viral target.
Virus Diseases
Cyclophilin D Regulates Antiviral CD8+ T Cell Survival in a Cell-Extrinsic Manner.
Virus Diseases
Cyclophilins and Their Roles in Hepatitis C Virus and Flavivirus Infections: Perspectives for Novel Antiviral Approaches.
Virus Diseases
From chemical tools to clinical medicines: nonimmunosuppressive cyclophilin inhibitors derived from the cyclosporin and sanglifehrin scaffolds.
Virus Diseases
Incidence, risk factors, and outcome of herpes zoster in systemic lupus erythematosus.
Virus Diseases
Increased cortical expression of FK506 binding protein-51 in HIV-associated neurocognitive disorders.
Virus Diseases
Induction of cyclophilin A by influenza A virus infection facilitates group A Streptococcus coinfection.
Virus Diseases
Mitochondria-nucleus shuttling FK506-binding protein 51 interacts with TRAF proteins and facilitates the RIG-I-like receptor-mediated expression of type I IFN.
Virus Diseases
Quantitative proteomic analysis of the Anopheles gambiae (Diptera: Culicidae) midgut infected with o'nyong-nyong virus.
Virus Diseases
Redistribution of cyclophilin A to viral factories during vaccinia virus infection and its incorporation into mature particles.
Virus Diseases
SAR study of bisamides as cyclophilin a inhibitors for the development of host-targeting therapy for hepatitis C virus infection.
Virus Diseases
Structural and Functional Analysis of the C-Terminal Domain of Nup358/RanBP2.
Virus Diseases
Structure-Based Discovery of Novel Cyclophilin A Inhibitors for the Treatment of Hepatitis C Virus Infections.
Virus Diseases
The control of viral infection by tripartite motif proteins and cyclophilin A.
Virus Diseases
The effect of ursodeoxycholic acid in children with prolonged hepatitis A virus infection that may be a trigger factor for autoimmune hepatitis.
Virus Diseases
[Host genetic factors associated with susceptibility to HIV infection and progression of infection]
Waldenstrom Macroglobulinemia
Targeting B-lymphocyte stimulator/B-cell activating factor and a proliferation-inducing ligand in hematologic malignancies.
West Nile Fever
Quantitative proteomic analysis of the Anopheles gambiae (Diptera: Culicidae) midgut infected with o'nyong-nyong virus.
Whooping Cough
Crystallization and preliminary X-ray diffraction analysis of the peptidylprolyl isomerase Par27 of Bordetella pertussis.
Whooping Cough
Pharmacological Cyclophilin Inhibitors Prevent Intoxication of Mammalian Cells with Bordetella pertussis Toxin.
Whooping Cough
Structure and plasticity of the peptidyl-prolyl isomerase Par27 of Bordetella pertussis revealed by X-ray diffraction and small-angle X-ray scattering.
Whooping Cough
Sudden infant death and prevalence of whooping cough in the Swedish and Norwegian communities.
Whooping Cough
The peptidyl-prolyl isomerase and chaperone Par27 of Bordetella pertussis as the prototype for a new group of parvulins.
Whooping Cough
The virulence factor PEB4 (Cj0596) and the periplasmic protein Cj1289 are two structurally related SurA-like chaperones in the human pathogen Campylobacter jejuni.
Wiskott-Aldrich Syndrome
FKBP133: a novel mouse FK506-binding protein homolog alters growth cone morphology.
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PDB
SCOP
CATH
UNIPROT
ORGANISM
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SUBUNIT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
?
x * 53800, calculated for full-length protein, x * 17000, N-terminal fragment
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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
sitting drop vapor diffusion method, using 20% (w/v) PEG 3350 and 0.2 M NaI
structure of a relatively protease-resistant N-terminal fragment containing the PPIase domain, t 2.0 A resolution. Residues Arg56, Phe61, Ile62, Gln64, Ala102, Asn103, Phe114, Glu122, Leu123 and His127 in beta-strands 3, 4 and 6, as well as in the extended loop connecting beta-strands 6 and 7, form the proline-binding pocket
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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli BL21 Gold DE3 cells
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Davis, T.L.; Walker, J.R.; Campagna-Slater, V.; Finerty, P.J.; Paramanathan, R.; Bernstein, G.; MacKenzie, F.; Tempel, W.; Ouyang, H.; Lee, W.H.; Eisenmesser, E.Z.; Dhe-Paganon, S.
Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases
PLoS Biol.
8
e1000439
2010
Homo sapiens (O43447), Homo sapiens (P23284), Homo sapiens (P30405), Homo sapiens (P45877), Homo sapiens (P62937), Homo sapiens (Q08752), Homo sapiens (Q13427), Homo sapiens (Q6UX04), Homo sapiens (Q9UNP9), Homo sapiens
brenda
Ulrich, A.; Wahl, M.C.
Structure and evolution of the spliceosomal peptidyl-prolyl cis-trans isomerase Cwc27
Acta Crystallogr. Sect. D
70
3110-3123
2014
Homo sapiens (Q6UX04), Homo sapiens, Thermochaetoides thermophila (G0RY38), Thermochaetoides thermophila DSM 1495 (G0RY38)
brenda
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Release 2023.1 (January 2023)
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