Information on EC 5.2.1.12 - zeta-carotene isomerase

for references in articles please use BRENDA:EC5.2.1.12
Word Map on EC 5.2.1.12
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Select one or more organisms in this record:

The enzyme appears in viruses and cellular organisms

top print hide
EC NUMBER
COMMENTARY hide
5.2.1.12
-
top print hide
RECOMMENDED NAME
GeneOntology No.
zeta-carotene isomerase
top print hide
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
9,15,9'-tricis-zeta-carotene = 9,9'-dicis-zeta-carotene
show the reaction diagram
-
-
-
-
top print hide
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria)
-
-
carotenoid biosynthesis
-
-
Carotenoid biosynthesis
-
-
Metabolic pathways
-
-
Biosynthesis of secondary metabolites
-
-
top print hide
SYSTEMATIC NAME
IUBMB Comments
9,15,9'-tricis-zeta-carotene cis-trans-isomerase
The enzyme catalyses the cis-trans isomerization of the 15-15' carbon-carbon double bond in 9,15,9'-tricis-zeta-carotene, which is required for biosynthesis of all plant carotenoids. Requires heme b.
top
top print hide
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
top print hide
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
-
in absence of light, the 9,15,9'-tri-cis-zeta-carotene isomer accumulates in etiolated leaves and roots of maize plants carrying the recessive y9 allele in comparison to normal carotenoid composition in light-exposed y9 leaves
physiological function
top print hide
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
9,15,9'-tricis-zeta-carotene
9,9'-dicis-zeta-carotene
show the reaction diagram
top print hide
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
9,15,9'-tricis-zeta-carotene
9,9'-dicis-zeta-carotene
show the reaction diagram
top print hide
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
top print hide
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
top
top
top
LINKS TO OTHER DATABASES (specific for EC-Number 5.2.1.12)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
InterPro (database of protein families, domains and functional sites)