Reference on EC 5.1.3.8 - N-acylglucosamine 2-epimerase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Van Rinsum, J.; van Dijk, W.; Hooghwinkel, G.J.M.; Ferwerda, W.
Subcellular localization and tissue distribution of sialic acid precursor-forming enzymes
Biochem. J.
210
21-28
1983
Rattus norvegicus
Corfield, A.P.; Clamp, J.R.; Wagner, S.A.
The metabolism of sialic acids in isolated rat colonic mucosal cells
Biochem. Soc. Trans.
11
767-768
1983
Rattus norvegicus
-
Corfield, A.P.; Rainey, J.B.; Clamp, J.R.; Wagner, S.A.
Rat colonic mucosal cell sialic acid metabolism in azoxymethane-induced tumours
Biochim. Biophys. Acta
840
264-270
1985
Rattus norvegicus
Corfield, A.P.; Clamp, J.R.; Wagner, S.A.
The metabolism of sialic acids in isolated rat colonic mucosal cells
Biochem. J.
226
163-174
1985
Rattus norvegicus
Datta, A.
N-Acetylglucosamine 2-epimerase from hog kidney
Methods Enzymol.
41
407-412
1975
Sus scrofa
Ghosh, S.; Roseman, S.
N-Acetylglucosamine 2-epimerase from hog kidney
Methods Enzymol.
8
191-195
1966
Sus scrofa
-
Ghosh, S.; Roseman, S.
The sialic acids. V. N-Acyl-D-glucosamine 2-epimerase
J. Biol. Chem.
240
1531-1536
1965
Sus scrofa
Maru, I.; Ohta, Y.; Murata, K.; Tsukada, Y.
Molecular cloning and identification of N-acetyl-D-glucosamine 2-epimerase from porcine kidney as a renin-binding protein
J. Biol. Chem.
271
16294-16299
1996
Sus scrofa (P17560), Sus scrofa
Maru, I.; Ohnishi, J.; Ohta, Y.; Hashimoto, W.; Tsukada, Y.; Murata, K.; Mikami, B.
Crystallization and preliminary X-ray diffraction studies of N-acetyl-D-glucosamine 2-epimerase from porcine kidney
J. Biochem.
120
481-482
1996
Sus scrofa
Maru, I.; Ohnishi, J.; Ohta, Y.; Tsukada, Y.
Simple and large-scale production of N-acetylneuraminic acid from N-acetyl-D-glucosamine and pyruvate using N-acyl-D-glucosamine 2-epimerase and N-acetylneuraminate lyase
Carbohydr. Res.
306
575-578
1998
Escherichia coli
Corfield, A.P.; Rainey, J.B.; Clamp, J.R.; Wagner, S.A.
Changes in the activity of the enzymes involved in sialic acid metabolism in isolated rat colonic mucosal cells on administration of azoxymethane
Biochem. Soc. Trans.
11
766-767
1983
Rattus norvegicus
-
Tabata, K.; Koizumi, S.; Endo, T.; Ozaki, A.
Production of N-acetyl-D-neuraminic acid by coupling bacteria expressing N-acetyl-D-glucosamine 2-epimerase and N-acetyl-D-neuraminic acid synthetase
Enzyme Microb. Technol.
30
327-333
2002
Synechocystis sp.
-
Takahashi, S.; Takahashi, K.; Kaneko, T.; Ogasawara, H.; Shindo, S.; Kobayashi, M.
Human renin-binding protein is the enzyme N-acetyl-D-glucosamine 2-epimerase
J. Biochem.
125
348-353
1999
Homo sapiens
Takahashi, S.; Takahashi, K.; Kaneko, T.; Ogasawara, H.; Shindo, S.; Saito, K.; Kobayashi, M.
Identification of cysteine-380 as the essential residue for the human N-acetyl-D-glucosamine 2-epimerase (renin binding protein)
J. Biochem.
126
639-642
1999
Homo sapiens
Takahashi, S.; Kumagai, M.; Shindo, S.; Saito, K.; Kawamura, Y.
Renin inhibits N-acetyl-D-glucosamine 2-epimerase (renin-binding protein)
J. Biochem.
128
951-956
2000
Homo sapiens
Takahashi, S.; Takahashi, K.; Kaneko, T.; Ogasawara, H.; Shindo, S.; Saito, K.; Kawamura, Y.
Identification of functionally important cysteine residues of the human renin-binding protein as the enzyme N-acetyl-D-glucosamine 2-epimerase
J. Biochem.
129
529-535
2001
Homo sapiens
Takahashi, S.; Ogasawara, H.; Takahashi, K.; Hori, K.; Saito, K.; Mori, K.
Identification of a domain conferring nucleotide binding to the N-acetyl-D-glucosamine 2-epimerase (renin binding protein)
J. Biochem.
131
605-610
2002
Homo sapiens, Rattus norvegicus
Luchansky, S.J.; Yarema, K.J.; Takahashi, S.; Bertozzi, C.R.
GlcNAc 2-epimerase can serve a catabolic role in sialic acid metabolism
J. Biol. Chem.
278
8035-8042
2003
Homo sapiens
Itoh, T.; Mikami, B.; Maru, I.; Ohta, Y.; Hashimoto, W.; Murata, K.
Crystal structure of N-acyl-D-glucosamine 2-epimerase from porcine kidney at 2.0 A resolution
J. Mol. Biol.
303
733-744
2000
Sus scrofa
Lee, J.O.; Yi, J.K.; Lee, S.G.; Takahashi, S.; Kim, B.G.
Production of N-acetylneuraminic acid from N-acetylglucosamine and pyruvate using recombinant human renin binding protein and sialic acid aldolase in one pot
Enzyme Microb. Technol.
35
121-125
2004
Homo sapiens
-
Takahashi, S.; Hori, K.; Ogasawara, H.; Hiwatashi, K.; Sugiyama, T.
Effects of nucleotides on the interaction of renin with GlcNAc 2-epimerase (renin binding protein, RnBP)
J. Biochem.
140
725-730
2006
Sus scrofa (P17560), Sus scrofa
Lee, Y.C.; Chien, H.C.; Hsu, W.H.
Production of N-acetyl-D-neuraminic acid by recombinant whole cells expressing Anabaena sp. CH1 N-acetyl-D-glucosamine 2-epimerase and Escherichia coli N-acetyl-D-neuraminic acid lyase
J. Biotechnol.
129
453-460
2007
Anabaena sp. CH1 (A4UA16), Sus scrofa (P17560), Sus scrofa
Lee, Y.C.; Wu, H.M.; Chang, Y.N.; Wang, W.C.; Hsu, W.H.
The central cavity from the (alpha/alpha)6 barrel structure of Anabaena sp. CH1 N-acetyl-D-glucosamine 2-epimerase contains two key histidine residues for reversible conversion
J. Mol. Biol.
367
895-908
2007
Anabaena sp. CH1 (A4UA16)
Hu, S.; Chen, J.; Yang, Z.; Shao, L.; Bai, H.; Luo, J.; Jiang, W.; Yang, Y.
Coupled bioconversion for preparation of N-acetyl-D-neuraminic acid using immobilized N-acetyl-D-glucosamine-2-epimerase and N-acetyl-D-neuraminic acid lyase
Appl. Microbiol. Biotechnol.
85
1383-1391
2010
Sus scrofa (P17560)
Zhang, Y.; Tao, F.; Du, M.; Ma, C.; Qiu, J.; Gu, L.; He, X.; Xu, P.
An efficient method for N-acetyl-D-neuraminic acid production using coupled bacterial cells with a safe temperature-induced system
Appl. Microbiol. Biotechnol.
86
481-489
2010
Synechocystis sp. PCC 6803
Sola-Carvajal, A.; Sanchez-Carron, G.; Garcia-Garcia, M.I.; Garcia-Carmona, F.; Sanchez-Ferrer, A.
Properties of BoAGE2, a second N-acetyl-D-glucosamine 2-epimerase from Bacteroides ovatus ATCC 8483
Biochimie
94
222-230
2012
Bacteroides ovatus (A7LVG6), Bacteroides ovatus ATCC 8483 (A7LVG6), Bacteroides ovatus ATCC 8483
Klermund, L.; Groher, A.; Castiglione, K.
New N-acyl-D-glucosamine 2-epimerases from cyanobacteria with high activity in the absence of ATP and low inhibition by pyruvate
J. Biotechnol.
168
256-263
2013
Acaryochloris marina, Acaryochloris marina MBIC 11017, Nostoc punctiforme, Nostoc sp., Nostoc sp. PCC 7120, Trichormus variabilis
Wang, S.; Laborda, P.; Lu, A.; Duan, X.; Ma, H.; Liu, L.; Voglmeir, J.
N-acetylglucosamine 2-epimerase from Pedobacter heparinus First experimental evidence of a deprotonation/reprotonation mechanism
Catalysts
6
212-228
2016
Pedobacter heparinus (C6Y403), Homo sapiens (P51606), Pedobacter heparinus ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3 (C6Y403)
-
Klermund, L.; Riederer, A.; Hunger, A.; Castiglione, K.
Protein engineering of a bacterial N-acyl-D-glucosamine 2-epimerase for improved stability under process conditions
Enzyme Microb. Technol.
87-88
70-78
2016
Trichormus variabilis (Q3M763)
Wang, Z.; Zhuang, W.; Cheng, J.; Sun, W.; Wu, J.; Chen, Y.; Ying, H.
In vivo multienzyme complex coconstruction of N-acetylneuraminic acid lyase and N-acetylglucosamine-2-epimerase for biosynthesis of N-acetylneuraminic acid
J. Agric. Food Chem.
65
7467-7475
2017
Anabaena sp. CH1 (A4UA16)
Kao, C.H.; Chen, Y.Y.; Wang, L.R.; Lee, Y.C.
Production of N-acetyl-D-neuraminic acid by recombinant single whole cells co-expressing N-acetyl-D-glucosamine-2-epimerase and N-acetyl-D-neuraminic acid aldolase
Mol. Biotechnol.
60
427-434
2018
Anabaena sp. CH1 (A4UA16)
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