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Information on EC 5.1.3.37 - mannuronan 5-epimerase

for references in articles please use BRENDA:EC5.1.3.37

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IUBMB Comments

The enzyme epimerizes the C-5 bond in some β-D-mannuronate residues in mannuronan, converting them to α-L-guluronate residues, and thus modifying the mannuronan into alginate. It is found in brown algae and alginate-producing bacterial species from the Pseudomonas and Azotobacter genera.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
alge4, alge6, alge1, alge2, mannuronan c5-epimerase, manc5-e, mep21, alginate epimerase, c5-mannuronan epimerase, mep26, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
[mannuronan]-beta-D-mannuronate = [alginate]-alpha-L-guluronate
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
alginate biosynthesis I (algal), alginate biosynthesis II (bacterial)