Information on EC 5.1.3.29 - L-fucose mutarotase and Organism(s) Homo sapiens and UniProt Accession A2VDF0

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Homo sapiens
UNIPROT: A2VDF0


The expected taxonomic range for this enzyme is: Bacteria, Eukaryota


The taxonomic range for the selected organisms is: Homo sapiens

EC NUMBER
COMMENTARY hide
5.1.3.29
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RECOMMENDED NAME
GeneOntology No.
L-fucose mutarotase
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
fucose degradation
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SYSTEMATIC NAME
IUBMB Comments
L-fucose 1-epimerase
This enzyme shows no 1-epimerase activity with D-glucose, L-rhamnose and D-fucose (cf. EC 5.1.3.3, aldose 1-epimerase) [1].
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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SwissProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
the mammalian mutarotase is functional in facilitated incorporation of fucose through the salvage pathway
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
alpha-L-fucopyranose
beta-L-fucopyranose
show the reaction diagram
the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway
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r
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
alpha-L-fucopyranose
beta-L-fucopyranose
show the reaction diagram
A2VDF0
the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway
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r
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli, cloned into pcDNA3.1 plasmid and transfected into HepG2 cells