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Information on EC 4.99.1.11 - sirohydrochlorin nickelchelatase

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IUBMB Comments
The enzyme, studied from the methanogenic archaeon Methanosarcina acetivorans, participates in the biosynthesis of the nickel-containing tetrapyrrole cofactor coenzyme F430, which is required by EC 2.8.4.1, coenzyme-B sulfoethylthiotransferase. It catalyses the insertion of the nickel ion into sirohydrochlorin.
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The expected taxonomic range for this enzyme is: Methanosarcina
Synonyms
nickel-specific chelatase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Ni-sirohydrochlorin + 2 H+ = sirohydrochlorin + Ni2+
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