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23S rRNA + H2O
?
-
cleavage of sarcin-ricin loop of 23S rRNA inhibits in vitro translation, slightly affects binding of elongation factor Tu ternary complex to the ribosome, inhibits elongation factor G binding, and consequently GTP hydrolysis and mRNA-tRNA translocation
-
-
?
23S rRNA containing guanosine-adenosine pair + H2O
an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
-
-
-
?
28 S rRNA + H2O
alpha-fragment from the 3' end of 28S rRNA
70S ribosomes + H2O
?
-
-
-
-
?
ApA + H2O
3'-AMP + adenosine
Escherichia coli 23S rRNA containing guanosine-adenosine pair + H2O
an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
-
-
-
-
?
Escherichia coli 28S rRNA containing guanosine-adenosine pair + H2O
an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
rabbit 28S rRNA containing guanosine-adenosine pair + H2O
an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
-
-
-
?
rabbit reticulocyte 28S rRNA containing guanosine-adenosine pair + H2O
an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
-
-
-
?
rabbit ribosomes + H2O
?
ribosomes isolated from reticulocyte lysate
-
-
?
Rattus norvegicus 28S rRNA containing guanosine-adenosine pair + H2O
an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
-
alpha-sarcin hydrolyzes a phosphodiester bond on the 3' side of a guanine residue 393 nucleotides from the 3' end. The alpha-sarcin domain is composed of a purine-rich sequence of 14 highly conserved nucleotides
-
-
?
ribosomes + H2O
?
-
-
-
?
Saccharomyces cerevisiae 28S rRNA containing guanosine-adenosine pair + H2O
an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
Saccharomyces cerevisiae rRNA containing guanosine-adenosine pair + H2O
an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
-
-
-
?
sarcin/ricin ribosomal loop RNA + H2O
?
-
-
-
?
SRL + H2O
?
-
sarcin/ricin loop in ribosomal RNA
-
-
?
supercoiled double-stranded DNA + H2O
nicked circular conformation of DNA
yeast 25S RNA + H2O
?
-
-
-
-
?
yeast 26 S RNA + H2O
?
-
alpha-sarcin cleaves the phosphodiester bond between the guanine residue at position 3025 and the adenine residue at position 3026
-
-
?
additional information
?
-
28 S rRNA + H2O
alpha-fragment from the 3' end of 28S rRNA
-
-
-
-
?
28 S rRNA + H2O
alpha-fragment from the 3' end of 28S rRNA
-
-
-
?
28 S rRNA + H2O
alpha-fragment from the 3' end of 28S rRNA
-
human rhabdomyosarcoma 28S rRNA
-
-
?
28 S rRNA + H2O
alpha-fragment from the 3' end of 28S rRNA
-
mini-stem-loop RNA
-
-
?
28 S rRNA + H2O
alpha-fragment from the 3' end of 28S rRNA
-
rat liver 28S rRNA
-
-
?
28 S rRNA + H2O
alpha-fragment from the 3' end of 28S rRNA
-
rat liver 28S rRNA
-
?
28 S rRNA + H2O
alpha-fragment from the 3' end of 28S rRNA
-
rat liver 28S rRNA
-
-
?
28 S rRNA + H2O
alpha-fragment from the 3' end of 28S rRNA
-
-
-
-
?
28 S rRNA + H2O
alpha-fragment from the 3' end of 28S rRNA
-
rat liver 28S rRNA
-
?
28 S rRNA + H2O
alpha-fragment from the 3' end of 28S rRNA
-
human rhabdomyosarcoma 28S rRNA
-
-
?
ApA + H2O
3'-AMP + adenosine
-
-
-
-
?
ApA + H2O
3'-AMP + adenosine
-
-
-
?
ApA + H2O
3'-AMP + adenosine
-
reaction of alpha-sarcin on ApA is composed of 2 steps, transphosphorylation adenosine + 2',3'-cyclic adenosine monophosphate are the reaction products, followed by hydrolysis of the cyclic mononucleotide, producing 3'-AMP
-
-
?
ApA + H2O
3'-AMP + adenosine
-
-
-
-
?
Escherichia coli 28S rRNA containing guanosine-adenosine pair + H2O
an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
-
-
-
-
?
Escherichia coli 28S rRNA containing guanosine-adenosine pair + H2O
an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
-
-
-
?
Escherichia coli 28S rRNA containing guanosine-adenosine pair + H2O
an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
-
-
-
-
?
GpA + H2O
3'-GMP
-
hydrolysis of the 3'-5' phosphodiester bond of the substrate yields 2',3'-cyclic adenosine mononucleotide, this intermediate is converted into the corresponding 3'-monophosphate derivative as the final product of the reaction
-
-
?
GpA + H2O
3'-GMP
-
hydrolysis of the 3'-5' phosphodiester bond of the substrate yields 2',3'-cyclic adenosine mononucleotide, this intermediate is converted into the corresponding 3'-monophosphate derivative as the final product of the reaction
-
-
?
RNA + H2O
?
-
-
-
-
?
RNA + H2O
?
-
hydrolyzes naked RNA at purines in both single-and double-stranded regions
-
-
?
RNA + H2O
?
hydrolyzes naked RNA at purines in both single-and double-stranded regions
-
-
?
RNA + H2O
?
-
with total rRNA as substrate alpha-sarcin causes extensive progressive digestion of nucleic acids
-
-
?
rRNA + H2O
?
-
-
646298, 646299, 646300, 646301, 646302, 646303, 646304, 646305, 646306, 646307, 646308, 646309, 646310, 646311, 646312, 646314, 646315, 646316, 646318, 646319, 646320, 646321 -
-
?
Saccharomyces cerevisiae 28S rRNA containing guanosine-adenosine pair + H2O
an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
-
-
-
-
?
Saccharomyces cerevisiae 28S rRNA containing guanosine-adenosine pair + H2O
an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
-
-
-
-
?
supercoiled double-stranded DNA + H2O
nicked circular conformation of DNA
-
-
-
-
?
supercoiled double-stranded DNA + H2O
nicked circular conformation of DNA
-
no effect on linear DNA
at low concentrations, further into a linear form at high concentrations
?
additional information
?
-
-
alpha-sarcin cleavage site lies between a guanosine and adenosine residue in the sequence AGUACGAG AGGAAG
-
-
?
additional information
?
-
-
specific ribonuclease activity against ribosomal RNA causes ribosome disruption and subsequent protein biosynthesis inhibition
-
-
?
additional information
?
-
-
major type II ribotoxin
-
-
?
additional information
?
-
-
mechanism of action is hydrolysis of a phosphodiester bond between G-4325 and A-4326 of rat 28S ribosomal RNA producing an alpha-fragment from the 3' end of 28S rRNA
-
-
?
additional information
?
-
-
alpha-sarcin modifies neighbouring sites in the sarcin/ricin loop of 28S rRNA, destroying the necessary dynamic flexibility of the ribosome, inhibiting the elongation factor assisted steps of the elongation cycle
-
-
?
additional information
?
-
-
induction of cell death via apoptosis
-
-
?
additional information
?
-
deletion mutant delta(7-22) exhibits activity against naked rRNA and synthetic substrates but lacks the specific ability of the wild-type protein to degrade rRNA in intact ribosomes
-
-
?
additional information
?
-
-
arginine 121 is a crucial residue for the specific cytotoxic activity of alpha-sarcin
-
-
?
additional information
?
-
-
acts as a cyclizing ribonuclease
-
-
?
additional information
?
-
-
acts as a cyclizing ribonuclease
-
-
?
additional information
?
-
-
acts as a cyclizing ribonuclease
-
-
?
additional information
?
-
-
alpha-sarcin site nucleotide sequence is identical in the large rRNAs of cytoplasmic ribosomes from a range of evolutionary diverse organisms, evolutionarily conserved in all eukaryotes and prokaryotes so far tested
-
-
?
additional information
?
-
-
alpha-sarcin site nucleotide sequence is identical in the large rRNAs of cytoplasmic ribosomes from a range of evolutionary diverse organisms, evolutionarily conserved in all eukaryotes and prokaryotes so far tested
-
-
?
additional information
?
-
-
alpha-sarcin site nucleotide sequence is identical in the large rRNAs of cytoplasmic ribosomes from a range of evolutionary diverse organisms, evolutionarily conserved in all eukaryotes and prokaryotes so far tested
-
-
?
additional information
?
-
alpha-sarcin site nucleotide sequence is identical in the large rRNAs of cytoplasmic ribosomes from a range of evolutionary diverse organisms, evolutionarily conserved in all eukaryotes and prokaryotes so far tested
-
-
?
additional information
?
-
-
with rat liver ribosomes or 60S ribosomal subunits as substrates alpha-sarcin cleaves a single oligonucleotide of about 488 residues, the alpha-fragment from the 3' end of 28 S rRNA, 40 S ribosomal subunits are not affected by the enzyme, hydrolysis of DNA requires large amounts of the toxin
-
-
?
additional information
?
-
-
cytotoxic protein that inhibits eukaryotic elongation factor 1 catalyzed binding of aminoacyl-tRNA to ribosomes as a result of cleaving a fragment from the large RNA in the 60 S ribosomal subunit
-
-
?
additional information
?
-
-
cytotoxic protein that inhibits eukaryotic elongation factor 1 catalyzed binding of aminoacyl-tRNA to ribosomes as a result of cleaving a fragment from the large RNA in the 60 S ribosomal subunit
-
-
?
additional information
?
-
-
leucine 145 plays a key role for determining the specificity of the ribosome-inactivating activity of the protein
-
-
?
additional information
?
-
-
the ribosome-inactivating proteins alpha-sarcin targets the ribosomal sarcin/ricin loop, specific recognition and cleavage. The eukaryotic ribosomal stalk directly interacts with several members of the N-glycosidase family, favoring their disruption of the sarcin/ricin loop, overview. alpha-Sarcin does not interact with the P1/P2 C-terminal peptide SDDDMGFGLFD
-
-
?
additional information
?
-
-
the rate of cleavage is comparable both in presence and in absence of ribosomal proteins. More complete cleavage is observed in the absence of ribosomal proteins
-
-
?
additional information
?
-
-
specific ribonuclease activity against ribosomal RNA causes ribosome disruption and subsequent protein biosynthesis inhibition
-
-
?
additional information
?
-
-
alpha-sarcin site nucleotide sequence is identical in the large rRNAs of cytoplasmic ribosomes from a range of evolutionary diverse organisms, evolutionarily conserved in all eukaryotes and prokaryotes so far tested
-
-
?
additional information
?
-
-
mechanism of action is hydrolysis of a phosphodiester bond between G-4325 and A-4326 of rat 28S ribosomal RNA producing an alpha-fragment from the 3' end of 28S rRNA
-
-
?
additional information
?
-
-
acts as a cyclizing ribonuclease
-
-
?
additional information
?
-
-
acts as a cyclizing ribonuclease
-
-
?
additional information
?
-
-
induction of cell death via apoptosis
-
-
?
additional information
?
-
-
the rate of cleavage is comparable both in presence and in absence of ribosomal proteins. More complete cleavage is observed in the absence of ribosomal proteins
-
-
?
additional information
?
-
ageritin shows specific ribonucleolytic activity against the ribosomal sarcin-ricin loop in a rabbit reticulocytes assay
-
-
?
additional information
?
-
-
hybridization, pH 7.55, 350 mM of monovalent cations, 10 mM MgCl2, 37°C
-
-
?
additional information
?
-
-
cleaving a specific adenine from the highly conserved alpha-sarcin loop of the host 28S ribosomal RNA
-
-
?
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Adenocarcinoma
Ultrastructural changes induced by alpha-sarcin in a human pulmonary tumor grown in naked mice.
Aspergillosis
Analysis of the major proteins secreted by the human opportunistic pathogen Aspergillus fumigatus under in vitro conditions.
Aspergillosis
Secretion of a potential virulence factor, a fungal ribonucleotoxin, during human aspergillosis infections.
Aspergillosis
Use of recombinant mitogillin for improved serodiagnosis of Aspergillus fumigatus-associated diseases.
Aspergillosis, Allergic Bronchopulmonary
Immunodominant peptide epitopes of allergen, Asp f 1 from the fungus Aspergillus fumigatus.
Brain Neoplasms
Purification, characterization and cytotoxicity assessment of Ageritin: The first ribotoxin from the basidiomycete mushroom Agrocybe aegerita.
Breast Neoplasms
Immunoconjugate generation between the ribosome inactivating protein restrictocin and an anti-human breast carcinoma MAB.
Carcinoma
Biochemical, cytotoxic and pharmacokinetic properties of an immunotoxin composed of a mouse monoclonal antibody Fib75 and the ribosome-inactivating protein alpha-sarcin from Aspergillus giganteus.
Carcinoma
Preparation of an engineered safer immunotoxin against colon carcinoma based on the ribotoxin hirsutellin A.
Colorectal Neoplasms
Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin ?-sarcin in nude mice bearing human colorectal cancer xenografts.
Colorectal Neoplasms
Inclusion of a Furin Cleavage Site Enhances Antitumor Efficacy against Colorectal Cancer Cells of Ribotoxin ?-Sarcin- or RNase T1-Based Immunotoxins.
Infections
Analysis of the major proteins secreted by the human opportunistic pathogen Aspergillus fumigatus under in vitro conditions.
Infections
Beauveria bassiana ribotoxin inhibits insect immunity responses to facilitate infection via host translational blockage.
Infections
Entry of feline calicivirus is dependent on clathrin-mediated endocytosis and acidification in endosomes.
Infections
Permeability to inhibitors of protein synthesis in virus infected cells.
Infections
Virulence of Aspergillus fumigatus double mutants lacking restriction and an alkaline protease in a low-dose model of invasive pulmonary aspergillosis.
Influenza in Birds
Effects of edeine, hygromycin B and alpha-Sarcin on influenza virus reproduction.
Influenza, Human
Effects of edeine, hygromycin B and alpha-Sarcin on influenza virus reproduction.
Invasive Pulmonary Aspergillosis
Aspergillus fumigatus and Its Allergenic Ribotoxin Asp f I: Old Enemies but New Opportunities for Urine-Based Detection of Invasive Pulmonary Aspergillosis Using Lateral-Flow Technology.
Invasive Pulmonary Aspergillosis
Construction and pathogenicity of Aspergillus fumigatus mutants that do not produce the ribotoxin restrictocin.
Invasive Pulmonary Aspergillosis
Effects of alkaline protease or restrictocin deficient mutants of Aspergillus fumigatus on human polymorphonuclear leukocytes.
Invasive Pulmonary Aspergillosis
Use of recombinant mitogillin for improved serodiagnosis of Aspergillus fumigatus-associated diseases.
Mycoses
Characterization of the Aspergillus fumigatus chitosanase CsnB and evaluation of its potential use in serological diagnostics.
Neoplasms
Deletion of the NH2-terminal beta-hairpin of the ribotoxin alpha-sarcin produces a nontoxic but active ribonuclease.
Neoplasms
Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin ?-sarcin in nude mice bearing human colorectal cancer xenografts.
Neoplasms
Evaluation of mitogillin (NSC-69529) in the treatment of naturally occurring canine neoplasms.
Neoplasms
Inclusion of a Furin Cleavage Site Enhances Antitumor Efficacy against Colorectal Cancer Cells of Ribotoxin ?-Sarcin- or RNase T1-Based Immunotoxins.
Neoplasms
Kinetic study of the cytotoxic effect of alpha-sarcin, a ribosome inactivating protein from Aspergillus giganteus, on tumour cell lines: protein biosynthesis inhibition and cell binding.
Neoplasms
Noncytotoxic ribonuclease, RNase T1, induces tumor cell death via hemagglutinating virus of Japan envelope vector.
Neoplasms
Purification, characterization and cytotoxicity assessment of Ageritin: The first ribotoxin from the basidiomycete mushroom Agrocybe aegerita.
Neoplasms
Study of the interaction between the antitumour protein alpha-sarcin and phospholipid vesicles.
Neoplasms
Toxicity and membrane perturbation properties of the ribotoxin-like protein Ageritin.
Neoplasms
Ultrastructural changes induced by alpha-sarcin in a human pulmonary tumor grown in naked mice.
Neuroblastoma
Ageritin from poplar mushrooms: scale-up purification and cytotoxicity towards undifferentiated and differentiated SH-SY5Y cells.
Rhabdomyosarcoma
Cytotoxic mechanism of the ribotoxin alpha-sarcin. Induction of cell death via apoptosis.
Rotavirus Infections
Rotaviruses induce an early membrane permeabilization of MA104 cells and do not require a low intracellular Ca2+ concentration to initiate their replication cycle.
Starvation
Iron - A Key Nexus in the Virulence of Aspergillus fumigatus.
Tuberculosis
[Antisense oligonucleotides inhibiting ribosomal functions in mycobacteria]
Virus Diseases
Proteins are cointernalized with virion particles during early infection.
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Endo, Y.; Wool, I.G.
The site of action of alpha-sarcin on eukaryotic ribosomes. The sequence at the alpha-sarcin cleavage site in 28 S ribosomal ribonucleic acid
J. Biol. Chem.
257
9054-9060
1982
Aspergillus giganteus
brenda
Endo, Y.; Huber, P.W.; Wool, I.G.
The ribonuclease activity of the cytotoxin alpha-sarcin. The characteristics of the enzymatic activity of alpha-sarcin with ribosomes and ribonucleic acids as substrates
J. Biol. Chem.
258
2662-2667
1983
Aspergillus giganteus
brenda
Wool, I.G.
The mechanism of the action of the cytotoxic nuclease alpha-sarcin and its use to analyze ribosome structure
Trends Biochem. Sci.
9
14-17
1984
Aspergillus giganteus
-
brenda
Stirpe, F.; Bailey, S.; Miller, S.P.; Bodley, J.W.
Modification of ribosomal RNA by ribosome-inactivating proteins from plants
Nucleic Acids Res.
16
1349-1357
1988
Aspergillus giganteus
brenda
Ling, J.; Liu, W.; Wang, T.P.
Cleavage of supercoiled double-stranded DNA by several ribosome-inactivating proteins in vitro
FEBS Lett.
345
143-146
1994
Aspergillus giganteus
brenda
Gasset, M.; Mancheno, J.M.; Laynez, J.; Lacadena, J.; Fernandez-Ballester, G.; Martinez del Pozo, A.; Onaderra, M.; Gavilanes, J.G.
Thermal unfolding of the cytotoxin alpha-sarcin: phospholipid binding induces destabilization of the protein structure
Biochim. Biophys. Acta
1252
126-134
1995
Aspergillus giganteus, Aspergillus giganteus MDH 18894
brenda
Lacadena, J.; Mancheno, J.M.; Martinez-Ruiz, A.; Martinez del Pozo, A.; Gasset, M.; Onaderra, M.; Gavilanes, J.G.
Substitution of histidine-137 by glutamine abolishes the catalytic activity of the ribosome-inactivating protein alpha-sarcin
Biochem. J.
309
581-586
1995
Aspergillus giganteus, Aspergillus giganteus MDH 18894
brenda
Campos-Olivas, R.; Bruix, M.; Santoro, J.; Martinez del Pozo, A.; Lacadena, J.; Gavilanes, J.G.; Rico, M.
Structural basis for the catalytic mechanism and substrate specificity of the ribonuclease alpha-sarcin
FEBS Lett.
399
163-165
1996
Aspergillus giganteus
brenda
Cheung, J.I.; Wang, Y.R.; Lin, A.
Substrate specificity of monomeric and dimeric alpha-sarcin
FEBS Lett.
386
60-64
1996
Aspergillus giganteus
brenda
Sylvester, I.D.; Roberts, L.M.; Lord, J.M.
Characterization of prokaryotic recombinant Aspergillus ribotoxin alpha-sarcin
Biochim. Biophys. Acta
1358
53-60
1997
Aspergillus giganteus
brenda
Hao, J.J.; Xu, Y-z.; Geng, C.d.; Liu, W.Y.; Wang, E.d; Gong, Z.z.; Ulbrich, N.
Purification of alpha-sarcin and an antifungal protein from Aspergillus giganteus by blue sepharose CL-6B affinity chromatography
Protein Expr. Purif.
14
295-301
1998
Aspergillus giganteus, Aspergillus giganteus MDH 18894
brenda
Lacadena, J.; Martinez del Pozo, A.; Lacadena, V.; Martinez-Ruiz, A.; Mancheno, J.M.; Onaderra, M.; Gavilanes, J.G.
The cytotoxin alpha-sarcin behaves as a cyclizing ribonuclease
FEBS Lett.
424
46-48
1998
Aspergillus giganteus, Aspergillus giganteus MDH 18894
brenda
Perez-Canadillas, J.M.; Campos-Olivas, R.; Lacadena, J.; Martinez del Pozo, A.; Gavilanes, J.G.; Santoro, J.; Rico, M.; Bruix, M.
Characterization of pKa values and titration shifts in the cytotoxic ribonuclease alpha-sarcin by NMR. Relationship between electrostatic interactions, structure, and catalytic function
Biochemistry
37
15865-15876
1998
Aspergillus giganteus
brenda
Lacadena, J.; Martinez del Pozo, A.; Martinez-Ruiz, A.; Perez-Canadillas, J.M.; Bruix, M.; Mancheno, J.M.; Onaderra, M.; Gavilanes, J.G.
Role of histidine-50, glutamic acid-96, and histidine-137 in the ribonucleolytic mechanism of the ribotoxin alpha-sarcin
Proteins
37
474-484
1999
Aspergillus giganteus, Aspergillus giganteus MDH 18894
brenda
Hwu, L.; Huang, K.; Chen, D.; Lin, A.
The action mode of the ribosome-inactivating protein alpha-sarcin
J. Biomed. Sci.
7
420-428
2000
Aspergillus giganteus
brenda
Perez-Canadillas, J.M.; Santoro, J.; Campos-Olivas, R.; Lacadena, J.; Martinez del Pozo, A.; Gavilanes, J.G.; Rico, M.; Bruix, M.
The highly refined solution structure of the cytotoxic ribonuclease alpha-sarcin reveals the structural requirements for substrate recognition and ribonucleolytic activity
J. Mol. Biol.
299
1061-1073
2000
Aspergillus giganteus (P00655)
brenda
Xu, Y.Z.; Liu, W.Y.
Effects of the active aldehyde group generated by RNA N-glycosidase in the sarcin/ricin domain of rat 28S ribosomal RNA on peptide elongation
Biol. Chem.
381
113-119
2000
Aspergillus giganteus
brenda
Masip, M.; Lacadena, J.; Mancheno, J.M.; Onaderra, M.; Martinez-Ruiz, A.; Martinez del Pozo, A.; Gavilanes, J.G.
Arginine 121 is a crucial residue for the specific cytotoxic activity of the ribotoxin alpha-sarcin
Eur. J. Biochem.
268
6190-6196
2001
Aspergillus giganteus
brenda
Olmo, N.; Turnay, J.; Gonzalez de Buitrago, G.; Lopez de Silanes, I.; Gavilanes, J.G.; Lizarbe, M.A.
Cytotoxic mechanism of the ribotoxin alpha-sarcin. Induction of cell death via apoptosis
Eur. J. Biochem.
268
2113-2123
2001
Aspergillus giganteus, Aspergillus giganteus MDH 18894
brenda
Garcia-Ortega, L.; Masip, M.; Mancheno, J.M.; Onaderra, M.; Lizarbe, M.A.; Garcia-Mayoral, M.F.; Bruix, M.; Martinez del Pozo, A.; Gavilanes, J.G.
Deletion of the NH2-terminal beta-hairpin of the ribotoxin alpha-sarcin produces a nontoxic but active ribonuclease
J. Biol. Chem.
277
18632-18639
2002
Aspergillus giganteus (P00655)
brenda
Larsson, S.L.; Sloma, M.S.; Nygard, O.
Conformational changes in the structure of domains II and V of 28S rRNA in ribosomes treated with the translational inhibitors ricin or alpha-sarcin
Biochim. Biophys. Acta
1577
53-62
2002
Aspergillus giganteus
brenda
Liu, R.s.; Huang, H.; Yang, Q.; Liu, W.Y.
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