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Information on EC 4.6.1.22 - Bacillus subtilis ribonuclease

for references in articles please use BRENDA:EC4.6.1.22

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IUBMB Comments

This enzyme catalyses endonucleolytic cleavage to 2',3'-cyclic nucleotides. The cyclic products may be hydrolysed to the corresponding 3'-phosphates by 2',3'-cyclic-nucleotide 2'-phosphodiesterase (EC 3.1.4.16). The enzyme from B. subtilis is inhibited by ATP.

The enzyme appears in viruses and cellular organisms
Reaction Schemes
=
a 5'-hydroxy-ribonucleotide
+
n
nucleoside-2',3'-cyclophosphates

Synonyms
rnase y, rnase j, rnase j1, rnase j2, bacillus subtilis ribonuclease, ribonuclease p protein, endoribonuclease rnase y, bacisubin, ribonuclease rnase j1, ykqc/rnase j1, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
RNA = a 5'-hydroxy-ribonucleotide + n nucleoside-2',3'-cyclophosphates
show the reaction diagram
Highest Expressing Human Cell Lines
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