Any feedback?
Please rate this page

BRENDA support

show all | hide all No of entries

Information on EC - 3-chloro-D-alanine dehydrochlorinase

for references in articles please use BRENDA:EC4.5.1.2
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
A pyridoxal-phosphate protein. The enzyme cleaves a carbon-chlorine bond, releasing a chloride and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia. The latter reaction, which can occur spontaneously, can also be catalysed by EC, 2-iminobutanoate/2-iminopropanoate deaminase. The enzyme's activity can also result in beta-replacement reactions, e.g. in the presence of hydrogen sulfide it can convert 3-chloro-D-alanine into D-cysteine and chloride.
Specify your search results
Select one or more organisms in this record: ?
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The enzyme appears in viruses and cellular organisms
3-chloro-d-alanine chloride-lyase, 3-chloro-d-alanine dehydrochlorinase, more
3-chloro-D-alanine + H2O = pyruvate + chloride + NH3
show the reaction diagram
Select items on the left to see more content.