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Information on EC 4.4.1.39 - C-phycoerythrin alpha-cysteine-82 phycoerythrobilin lyase

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EC Tree
IUBMB Comments
The enzyme, characterized from the cyanobacterium Microchaete diplosiphon, catalyses the attachment of the phycobilin chromophore (3E)-phycoerythrobilin (PEB) to cysteine 82 of the alpha subunit of the phycobiliprotein C-phycoerythrin. The numbering used here corresponds to the enzyme from Microchaete diplosiphon, and could vary slightly in other organisms. Activity is greatly enhanced in the presence of the chaperone-like protein CpeZ. The reaction could also be catalysed by EC 4.4.1.29, phycobiliprotein cysteine-84 phycobilin lyase, but much less efficiently.
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
a [C-phycoerythrin alpha-subunit]-Cys82-phycoerythrobilin
=
apo-[C-phycocyanin alpha-subunit]
+
Synonyms
cpeY, FDUTEX481_07658, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a [C-phycoerythrin alpha-subunit]-Cys82-phycoerythrobilin = apo-[C-phycocyanin alpha-subunit] + (3E)-phycoerythrobilin
show the reaction diagram
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