Reference on EC 4.4.1.21 - S-ribosylhomocysteine lyase and Organism(s) Bacillus subtilis
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Das, S.K.; Sedelnikova, S.E.; Baker, P.J.; Ruzheinikov, S.N.; Foster, S.; Hartley, A.; Horsburgh, M.J.; Rice, D.W.
Cloning, purification, crystallization and preliminary crystallographic analysis of Bacillus subtilis LuxS
Acta Crystallogr. Sect. D
57
1324-1325
2001
Bacillus subtilis
Zhu, J.; Dizin, E.; Hu, X.; Wavreille, A.S.; Park, J.; Pei, D.
S-Ribosylhomocysteinase (LuxS) is a mononuclear iron protein
Biochemistry
42
4717-4726
2003
Bacillus subtilis
Ruzheinikov, S.N.; Das, S.K.; Sedelnikova, S.E.; Hartley, A.; Foster, S.J.; Horsburgh, M.J.; Cox, A.G.; McCleod, C.W.; Mekhalfia, A.; Blackburn, G.M.; Rice, D.W.; Baker, P.J.
The 1.2 A structure of a novel quorum-sensing protein, Bacillus subtilis LuxS
J. Mol. Biol.
313
111-122
2001
Bacillus subtilis (O34667)
Hilgers, M.T.; Ludwig, M.L.
Crystal structure of the quorum-sensing protein LuxS reveals a catalytic metal site
Proc. Natl. Acad. Sci. USA
98
11169-11174
2001
Bacillus subtilis (O34667)
Zhu, J.; Patel, R.; Pei, D.
Catalytic mechanism of S-ribosylhomocysteinase (LuxS): stereochemical course and kinetic isotope effect of proton transfer reactions
Biochemistry
43
10166-10172
2004
Bacillus subtilis, Vibrio harveyi
Rajan, R.; Zhu, J.; Hu, X.; Pei, D.; Bell, C.E.
Crystal structure of S-ribosylhomocysteinase (LuxS) in complex with a catalytic 2-ketone intermediate
Biochemistry
44
3745-3753
2005
Vibrio harveyi, Bacillus subtilis (O34667), Bacillus subtilis
Hullo, M.F.; Auger, S.; Soutourina, O.; Barzu, O.; Yvon, M.; Danchin, A.; Martin-Verstraete, I.
Conversion of methionine to cysteine in Bacillus subtilis and its regulation
J. Bacteriol.
189
187-197
2007
Bacillus subtilis (O34667), Bacillus subtilis 168 (O34667)
Zhu, J.; Knottenbelt, S.; Kirk, M.L.; Pei, D.
Catalytic mechanism of S-ribosylhomocysteinase: ionization state of active-site residues
Biochemistry
45
12195-12203
2006
Bacillus subtilis (O34667), Escherichia coli (P45578), Escherichia coli, Vibrio harveyi (Q9Z5X1)
Wnuk, S.F.; Lalama, J.; Robert, J.; Garmendia, C.A.
Novel S-ribosylhomocysteine analogues as potential inhibitors of LuxS enzyme
Nucleosides Nucleotides Nucleic Acids
26
1051-1055
2007
Bacillus subtilis (O34667)
Gopishetty, B.; Zhu, J.; Rajan, R.; Sobczak, A.J.; Wnuk, S.F.; Bell, C.E.; Pei, D.
Probing the catalytic mechanism of S-ribosylhomocysteinase (LuxS) with catalytic intermediates and substrate analogues
J. Am. Chem. Soc.
131
1243-1250
2009
Bacillus subtilis, Escherichia coli, Vibrio harveyi
Hardie, K.R.; Heurlier, K.
Establishing bacterial communities by word of mouth: LuxS and autoinducer 2 in biofilm development
Nat. Rev. Microbiol.
6
635-643
2008
Bacillus subtilis, Campylobacter jejuni, Escherichia coli, Haemophilus influenzae, Helicobacter pylori, Serratia plymuthica, Staphylococcus aureus, Vibrio harveyi
Wnuk, S.F.; Robert, J.; Sobczak, A.J.; Meyers, B.P.; Malladi, V.L.; Zhu, J.; Gopishetty, B.; Pei, D.
Inhibition of S-ribosylhomocysteinase (LuxS) by substrate analogues modified at the ribosyl C-3 position
Bioorg. Med. Chem.
17
6699-6706
2009
Bacillus subtilis (O34667)
Bhattacharyya, M.; Vishveshwara, S.
Functional correlation of bacterial LuxS with their quaternary associations: interface analysis of the structure networks
BMC Struct. Biol.
9
8
2009
Alkalihalobacillus clausii (Q5WDW1), Bacillus anthracis (Q81KF3), Bacillus cereus (Q816N5), Bacillus subtilis (O34667), Bifidobacterium longum (Q8G568), Campylobacter jejuni (Q9PN97), Clostridium perfringens (Q0SWJ6), Deinococcus geothermalis (Q1IW42), Deinococcus radiodurans (Q9RRU8), Escherichia coli (Q8X902), Haemophilus influenzae (P44007), Helicobacter pylori (Q9ZMW8), Lactobacillus acidophilus (Q5FK48), Lactobacillus johnsonii (Q74HV0), Limosilactobacillus reuteri (Q5QHW1), Psychromonas ingrahamii (A1SZZ2), Shigella flexneri (Q83JZ4), Staphylococcus aureus (Q6GEU1), Staphylococcus epidermidis (Q8CNI0), Streptococcus mutans (Q8DVK8), Streptococcus pyogenes (P0C0C7), Thermus thermophilus (Q72IE6), Vibrio cholerae (Q9KUG4)
Malladi, V.L.; Sobczak, A.J.; Meyer, T.M.; Pei, D.; Wnuk, S.F.
Inhibition of LuxS by S-ribosylhomocysteine analogues containing a [4-aza]ribose ring
Bioorg. Med. Chem.
19
5507-5519
2011
Bacillus subtilis