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Information on EC 4.4.1.17 - Holocytochrome-c synthase and Organism(s) Candida albicans and UniProt Accession P53700

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IUBMB Comments
In the reverse direction, the enzyme catalyses the attachment of heme to two cysteine residues in the protein, forming thioether links.
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This record set is specific for:
Candida albicans
UNIPROT: P53700
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Word Map
The taxonomic range for the selected organisms is: Candida albicans
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
system iii, heme lyase, cytochrome c heme lyase, cyc2p, holocytochrome c synthase, holocytochrome c-type synthase, ccsa1, holocytochrome c synthetase, cytochrome c synthase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
CCHL
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Cytochrome c heme-lyase
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Cytochrome c synthase
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Holocytochrome c synthetase
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Holocytochrome c-type synthase
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Holocytochrome-C synthase
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Holocytochrome-C-type synthase
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Synthetase, holocytochrome c
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
covalent attachment of heme
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PATHWAY SOURCE
PATHWAYS
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-, -
SYSTEMATIC NAME
IUBMB Comments
holocytochrome-c apocytochrome-c-lyase (heme-forming)
In the reverse direction, the enzyme catalyses the attachment of heme to two cysteine residues in the protein, forming thioether links.
CAS REGISTRY NUMBER
COMMENTARY hide
75139-03-6
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Apocytochrome c + heme
Holocytochrome c
show the reaction diagram
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-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
gene CaCYC3, 45% homology to the gene CYC3 of Saccharomyces cerevisiae
SwissProt
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
detected by Western analysis
Manually annotated by BRENDA team
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
cloning of the gene CaCYC3 in Escherichia coli
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Cervera, A.M.; Gozalbo, D.; McCreath, K.J.; Gow, N.A.R.; Martinez, J.P.; Casanova, M.
Molecular cloning and characterization of a Candida albicans gene coding for cytochrome c heme lyase and a cell wall-related protein
Mol. Microbiol.
30
67-81
1998
Candida albicans (P53700)
Manually annotated by BRENDA team