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Information on EC 4.4.1.16 - selenocysteine lyase

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IUBMB Comments
A pyridoxal-phosphate protein. Dithiothreitol or 2-mercaptoethanol can act as the reducing agent in the reaction. The enzyme from animals does not act on cysteine, serine or chloroalanine [1,3], while the enzyme from bacteria shows activity with cysteine (cf. EC 2.8.1.7, cysteine desulfurase) .
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
ABA3-NifS, cpSL, L-selenocysteine selenide-lyase, More, SCL, Scly, Sec lyase, selenocysteine beta-lyase, selenocysteine lyase, selenocysteine reductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-selenocysteine + reduced acceptor = selenide + L-alanine + acceptor
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PATHWAY SOURCE
PATHWAYS
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