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Information on EC 4.4.1.16 - selenocysteine lyase

for references in articles please use BRENDA:EC4.4.1.16

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IUBMB Comments

A pyridoxal-phosphate protein. Dithiothreitol or 2-sulfanylethan-1-ol (2-mercaptoethanol) can act as the reducing agent in the reaction. The enzyme from animals does not act on cysteine, serine or chloroalanine [1,3], while the enzyme from bacteria shows activity with cysteine (cf. EC 2.8.1.7, cysteine desulfurase) .

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

Synonyms
scl, selenocysteine lyase, selenocysteine beta-lyase, sec lyase, aba3-nifs, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-selenocysteine + reduced acceptor = selenide + L-alanine + acceptor
show the reaction diagram
PATHWAY SOURCE
PATHWAYS