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Reference on EC 4.3.3.2 - strictosidine synthase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kutchan, T.M.; Bock, A.; Dittrich, H.
Heterologous expression of the plant proteins strictosidine synthase and berberine bridge enzyme in insect cell culture
Phytochemistry
35
353-360
1994
Rauvolfia serpentina
Manually annotated by BRENDA team
Treimer, J.F.; Zenk, M.H.
Purification and properties of strictosidine synthase, the key enzyme in indole alkaloid formation
Eur. J. Biochem.
101
225-233
1979
Amsonia salicifolia, Amsonia tabernaemontana, Catharanthus longifolius, Catharanthus pusillus, Catharanthus roseus, Catharanthus trichophyllus, Ervatamia divaricatum, Ochrosia elliptica, Rauvolfia verticillata, Rauvolfia vomitoria, Amsonia orientalis, Stemmadenia tomentosa var. palmeri, Vinca major, Vinca minor, Voacanga africana
Manually annotated by BRENDA team
Mizukami, H.; Nordlov, H.; Lee, S.L.; Scott, A.I.
Purification and properties of strictosidine synthetase (an enzyme condensing tryptamine and secologanin) from Catharanthus roseus cultured cell
Biochemistry
18
3760-3763
1979
Catharanthus roseus
Manually annotated by BRENDA team
Treimer, J.F.; Zenk, M.H.
Strictosidine synthase from cell cultrues of Apocynaceae plants
FEBS Lett.
97
159-162
1979
Amsonia salicifolia, Catharanthus roseus, Ochrosia elliptica, Rauvolfia vomitoria, Amsonia orientalis, Stemmadenia tomentosa var. palmeri, Vinca major, Vinca minor, Voacanga africana
-
Manually annotated by BRENDA team
Pfitzner, U.; Zenk, M.H.
Immobilization of strictosidine synthase from Catharanthus cell cultures and preparative synthesis of strictosidine
Planta Med.
46
10-14
1982
Catharanthus roseus
Manually annotated by BRENDA team
Skinner, S.E.; Walton, N.J.; Robins, R.J.; Rhodes, M.J.C.
Tryptophan decarboxylase, strictosidine synthase and alkaloid production by Cinchona ledgerinana suspension cultures
Phytochemistry
26
721-725
1987
Cinchona calisaya
-
Manually annotated by BRENDA team
Pfitzner, U.; Zenk, M.H.
Isoation and immobilization of strictosidine synthase
Methods Enzymol.
136
342-350
1987
Catharanthus roseus
-
Manually annotated by BRENDA team
Hampp, N.; Zenk, M.H.
Homogeneous strictosidine synthase from cell suspension cultures of Rauvolfia serpentina
Phytochemistry
27
3811-3815
1988
Rauvolfia serpentina
-
Manually annotated by BRENDA team
Pennings, E.J.M.; Van den Bosch, R.A.; Van der Heijden, R.; Stevens, L.H.; Duine, J.A.; Verpoorte, R.
Assay of trictosidine synthase from plant cell cultures by high-performance liquid chromatography
Anal. Biochem.
176
412-415
1989
Catharanthus roseus, Tabernaemontana orientalis
Manually annotated by BRENDA team
Roessner, C.A.; Devagupta, R.; Hasan, M.; Williams, H.J.; Scott, A.I.
Purification of an indole alkaloid biosynthetic enzyme, strictosidine synthase, from a recombinant strain of Escherichia coli
Protein Expr. Purif.
3
295-300
1992
Catharanthus roseus
Manually annotated by BRENDA team
Bracher, D.; Kutchan, T.M.
Strictosidine synthase from Rauvolfia serpentina: analysis of a gene involved in indole alkaloid biosynthesis
Arch. Biochem. Biophys.
294
717-723
1992
Rauvolfia mannii, Rauvolfia serpentina
Manually annotated by BRENDA team
Stevens, L.H.; Giroud, C.; Pennings, E.J.M.; Verpoorte, R.
Purification and characterization of strictosidine synthase from a suspension culture of Cinchona robusta
Phytochemistry
33
99-106
1993
Catharanthus roseus, Cinchona robusta
-
Manually annotated by BRENDA team
de Waal, A.; Meijer, A.H.; Verpoorte, R.
Strictosidine synthase from Catharanthus roseus: purification and characterization of multiple forms
Biochem. J.
306
571-580
1995
Catharanthus roseus
Manually annotated by BRENDA team
Hallard, D.; Van der Heijden, R.; Verpoorte, R.; Lopes Cardoso, M.I.; Pasquali, G.; Memelink, J.; Hoge, J.H.C.
Suspension cultured transgenic cells of Nicotiana tabacum expressing tryptophan decarboxylase and strictosidine synthase cDNAs from Catharanthus roseus produce strictosidine upon secologanin feeding.
Plant Cell Rep.
17
50-54
1997
Catharanthus roseus
Manually annotated by BRENDA team
Canel, C.; Lopes-Cardoso, M.I.; Whitmer, S.; van der Fits, L.; Pasquali, G.; van der Heijden, R.; Hoge, J.H.; Verpoorte, R.
Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus
Planta
205
414-419
1998
Catharanthus roseus (P18417), Catharanthus roseus
Manually annotated by BRENDA team
Pasquali, G.; Erven, A.S.; Ouwerkerk, P.B.; Menke, F.L.; Memelink, J.
The promoter of the strictosidine synthase gene from periwinkle confers elicitor-inducible expression in transgenic tobacco and binds nuclear factors GT-1 and GBF
Plant Mol. Biol.
39
1299-1310
1999
Catharanthus roseus
Manually annotated by BRENDA team
Whitmer, S.; van der Heijden, R.; Verpoorte, R.
Effect of precursor feeding on alkaloid accumulation by a strictosidine synthase over-expressing transgenic cell line S1 of Catharanthus roseus
Plant Cell Tissue Organ Cult.
69
85-93
2002
Catharanthus roseus
-
Manually annotated by BRENDA team
Yamazaki, Y.; Urano, A.; Sudo, H.; Kitajima, M.; Takayama, H.; Yamazaki, M.; Aimi, N.; Saito, K.
Metabolite profiling of alkaloids and strictosidine synthase activity in camptothecin producing plants
Phytochemistry
62
461-470
2003
Ophiorrhiza pumila
Manually annotated by BRENDA team
Koepke, J.; Ma, X.; Fritzsch, G.; Michel, H.; Stockigt, J.
Crystallization and preliminary X-ray analysis of strictosidine synthase and its complex with the substrate tryptamine
Acta Crystallogr. Sect. D
61
690-693
2005
Rauvolfia serpentina
Manually annotated by BRENDA team
Ma, X.; Koepke, J.; Fritzsch, G.; Diem, R.; Kutchan, T.M.; Michel, H.; Stockigt, J.
Crystallization and preliminary X-ray crystallographic analysis of strictosidine synthase from Rauvolfia: the first member of a novel enzyme family
Biochim. Biophys. Acta
1702
121-124
2004
Rauvolfia serpentina
Manually annotated by BRENDA team
McCoy, E.; Galan, M.C.; O'Connor S.E.
Substrate specificity of strictosidine synthase
Bioorg. Med. Chem. Lett.
16
2475-2478
2006
Escherichia coli
Manually annotated by BRENDA team
Ma, X.; Panjikar, S.; Koepke, J.; Loris, E.; Stockigt, J.
The Structure of Rauvolfia serpentina Strictosidine Synthase Is a Novel Six-Bladed {beta}-Propeller Fold in Plant Proteins
Plant Cell
18
907-920
2006
Rauvolfia serpentina (P68175), Rauvolfia serpentina
Manually annotated by BRENDA team
Chen, S.; Galan, M.C.; Coltharp, C.; OConnor, S.E.
Redesign of a central enzyme in alkaloid biosynthesis
Chem. Biol.
13
1137-1141
2006
Catharanthus roseus
Manually annotated by BRENDA team
Bernhardt, P.; McCoy, E.; OConnor, S.E.
Rapid identification of enzyme variants for reengineered alkaloid biosynthesis in periwinkle
Chem. Biol.
14
888-897
2007
Catharanthus roseus
Manually annotated by BRENDA team
Loris, E.A.; Panjikar, S.; Ruppert, M.; Barleben, L.; Unger, M.; Schuebel, H.; Stoeckigt, J.
Structure-based engineering of strictosidine synthase: auxiliary for alkaloid libraries
Chem. Biol.
14
979-985
2007
Rauvolfia serpentina
Manually annotated by BRENDA team
Maresh, J.J.; Giddings, L.A.; Friedrich, A.; Loris, E.A.; Panjikar, S.; Trout, B.L.; Stoeckigt, J.; Peters, B.; OConnor, S.E.
Strictosidine synthase: mechanism of a Pictet-Spengler catalyzing enzyme
J. Am. Chem. Soc.
130
710-723
2008
Catharanthus roseus, Rauvolfia serpentina (P68175)
Manually annotated by BRENDA team
Sohani, M.M.; Schenk, P.M.; Schultz, C.J.; Schmidt, O.
Phylogenetic and transcriptional analysis of a strictosidine synthase-like gene family in Arabidopsis thaliana reveals involvement in plant defence responses
Plant Biol.
11
105-117
2009
Arabidopsis thaliana, Arabidopsis thaliana (Q9CAZ7), Arabidopsis thaliana (Q9SD04), Arabidopsis thaliana (Q9SD05), Arabidopsis thaliana (Q9SD07)
Manually annotated by BRENDA team
Stoeckigt, J.; Barleben, L.; Panjikar, S.; Loris, E.A.
3D-Structure and function of strictosidine synthase - the key enzyme of monoterpenoid indole alkaloid biosynthesis
Plant Physiol. Biochem.
46
340-355
2008
Catharanthus roseus (P18417), Rauvolfia serpentina (P68175), Rauvolfia serpentina
Manually annotated by BRENDA team
Chen, R.; Liao, Z.H.; Chen, M.; Wang, Q.; Yang, C.X.; Yang, Y.J.
Molecular cloning and characterization of the strictosidine synthase gene from Rauwolfia verticillata
Russ. J. Plant Physiol.
55
670-675
2008
Rauvolfia verticillata (Q1L6F4)
-
Manually annotated by BRENDA team
Yang, L.; Zou, H.; Zhu, H.; Ruppert, M.; Gong, J.; Stoeckigt, J.
Improved expression of His(6)-tagged strictosidine synthase cDNA for chemo-enzymatic alkaloid diversification
Chem. Biodivers.
7
860-870
2010
Rauvolfia serpentina (P68175)
Manually annotated by BRENDA team
Lu, Y.; Wang, H.; Wang, W.; Qian, Z.; Li, L.; Wang, J.; Zhou, G.; Kai, G.
Molecular characterization and expression analysis of a new cDNA encoding strictosidine synthase from Ophiorrhiza japonica
Mol. Biol. Rep.
36
1845-1852
2009
Ophiorrhiza japonica
Manually annotated by BRENDA team
Stockigt, J.; Hammes, B.; Ruppert, M.
Construction and expression of a dual vector for chemo-enzymatic synthesis of plant indole alkaloids in Escherichia coli
Nat. Prod. Res.
24
759-766
2010
Rauvolfia serpentina
Manually annotated by BRENDA team
Bernhardt, P.; OConnor, S.E.
Synthesis and biochemical evaluation of des-vinyl secologanin aglycones with alternate stereochemistry
Tetrahedron Lett.
50
7118-7120
2009
Rauvolfia serpentina (P68175)
Manually annotated by BRENDA team
Guirimand, G.; Courdavault, V.; Lanoue, A.; Mahroug, S.; Guihur, A.; Blanc, N.; Giglioli-Guivarch, N.; St-Pierre, B.; Burlat, V.
Strictosidine activation in Apocynaceae: Towards a nuclear time bomb?
BMC Plant Biol.
10
182
2010
Catharanthus roseus
Manually annotated by BRENDA team
Kusari, S.; Zuehlke, S.; Spiteller, M.
Effect of artificial reconstitution of the interaction between the plant Camptotheca acuminata and the fungal endophyte Fusarium solani on camptothecin biosynthesis
J. Nat. Prod.
74
764-775
2011
Camptotheca acuminata
Manually annotated by BRENDA team
Yamazaki, M.; Asano, T.; Yamazaki, Y.; Sirikantaramas, S.; Sudo, H.; Saito, K.
Biosynthetic system of camptothecin: An anticancer plant product
Pure Appl. Chem.
82
213-218
2010
Ophiorrhiza pumila (Q94LW9)
-
Manually annotated by BRENDA team
Fischereder, E.; Pressnitz, D.; Kroutil, W.; Lutz, S.
Engineering strictosidine synthase: rational design of a small, focused circular permutation library of the beta-propeller fold enzyme
Bioorg. Med. Chem.
22
5633-5637
2014
Rauvolfia serpentina
Manually annotated by BRENDA team
Vera-Reyes, I.; Huerta-Heredia, A.A.; Ponce-Noyola, T.; Flores-Sanchez, I.J.; Esparza-Garcia, F.; Cerda-Garcia-Rojas, C.M.; Trejo-Tapia, G.; Ramos-Valdivia, A.C.
Strictosidine-related enzymes involved in the alkaloid biosynthesis of Uncaria tomentosa root cultures grown under oxidative stress
Biotechnol. Prog.
29
621-630
2013
Uncaria tomentosa
Manually annotated by BRENDA team
Verma, P.; Sharma, A.; Khan, S.A.; Shanker, K.; Mathur, A.K.
Over-expression of Catharanthus roseus tryptophan decarboxylase and strictosidine synthase in rol gene integrated transgenic cell suspensions of Vinca minor
Protoplasma
252
373-381
2015
Catharanthus roseus (P18417), Catharanthus roseus
Manually annotated by BRENDA team
Pandey, S.S.; Singh, S.; Babu, C.S.; Shanker, K.; Srivastava, N.K.; Shukla, A.K.; Kalra, A.
Fungal endophytes of Catharanthus roseus enhance vindoline content by modulating structural and regulatory genes related to terpenoid indole alkaloid biosynthesis
Sci. Rep.
6
26583
2016
Catharanthus roseus (P18417), Catharanthus roseus
Manually annotated by BRENDA team
Cui, L.; Ni, X.; Ji, Q.; Teng, X.; Yang, Y.; Wu, C.; Zekria, D.; Zhang, D.; Kai, G.
Co-overexpression of geraniol-10-hydroxylase and strictosidine synthase improves anti-cancer drug camptothecin accumulation in Ophiorrhiza pumila
Sci. Rep.
5
8227
2015
Catharanthus roseus (P18417), Catharanthus roseus
Manually annotated by BRENDA team
Zhu, H.; Kercmar, P.; Wu, F.; Rajendran, C.; Sun, L.; Wang, M.; Stoeckigt, J.
Using strictosidine synthase to prepare novel alkaloids
Curr. Med. Chem.
22
1880-1888
2015
Rauvolfia serpentina (P68175)
Manually annotated by BRENDA team
Sharma, A.; Verma, P.; Mathur, A.; Mathur, A.K.
Overexpression of tryptophan decarboxylase and strictosidine synthase enhanced terpenoid indole alkaloid pathway activity and antineoplastic vinblastine biosynthesis in Catharanthus roseus
Protoplasma
255
1281-1294
2018
Catharanthus roseus (P18417), Catharanthus roseus
Manually annotated by BRENDA team
Zou, T.; Li, S.; Liu, M.; Wang, T.; Xiao, Q.; Chen, D.; Li, Q.; Liang, Y.; Zhu, J.; Liang, Y.; Deng, Q.; Wang, S.; Zheng, A.; Wang, L.; Li, P.
An atypical strictosidine synthase, OsSTRL2, plays key roles in anther development and pollen wall formation in rice
Sci. Rep.
7
6863
2017
Oryza sativa (Q84Q89), Oryza sativa
Manually annotated by BRENDA team
Soltani, N.; Nazarian-Firouzabadi, F.; Shafeinia, A.; Sadr, A.S.; Shirali, M.
The expression of terpenoid indole alkaloid (TIAs) pathway genes in Catharanthus roseus in response to salicylic acid treatment
Mol. Biol. Rep.
47
7009-7016
2020
Catharanthus roseus (P18417), Catharanthus roseus
Manually annotated by BRENDA team