Information on EC 220.127.116.11 - purine imidazole-ring cyclasefor references in articles please use BRENDA:EC18.104.22.168
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Also acts on 2,6-diamino-5-formamido-3,4-dihydro-4-oxopyrimidine residues. Brings about the reclosure of the imidazole rings of purine residues damaged by gamma-rays.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
cyclase, purine imidazole ring, PurIR cyclase, more
DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O
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