Reference on EC 4.3.2.10 - imidazole glycerol-phosphate synthase
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Banfield, M.J.; Lott, J.S.; Arcus, V.L.; McCarthy, A.A.; Baker, E.N.
Structure of HisF, a histidine biosynthetic protein from Pyrobaculum aerophilum
Acta Crystallogr. Sect. D
57
1518-1525
2001
Pyrobaculum aerophilum (Q8ZY16 AND Q8ZY40), Pyrobaculum aerophilum DSM 7523 (Q8ZY16 AND Q8ZY40)
Klem, T.J.; Davisson, V.J.
Imidazole glycerol phosphate synthase the glutamine amidotransferase in histidine biosynthesis
Biochemistry
32
5177-5186
1993
Escherichia coli, Escherichia coli K12
Chaudhuri, B.N.; Lange, S.C.; Myers, R.S.; Davisson, V.J.; Smith, J.L.
Toward understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerolphosphate synthase crystal structures of a ternary complex and the free enzyme
Biochemistry
42
7003-7012
2003
Saccharomyces cerevisiae (P33734), Saccharomyces cerevisiae ATCC 204508 (P33734)
Myers, R.S.; Jensen, J.R.; Deras, I.L.; Smith, J.L.; Davisson, V.J.
Substrate-induced changes in the ammonia channel for imidazole glycerol phosphate synthase
Biochemistry
42
7013-7022
2003
Saccharomyces cerevisiae (P33734), Saccharomyces cerevisiae ATCC 204508 (P33734)
Rivalta, I.; Lisi, G.P.; Snoeberger, N.S.; Manley, G.; Loria, J.P.; Batista, V.S.
Allosteric communication disrupted by a small molecule binding to the imidazole glycerol phosphate synthase protein-protein interface
Biochemistry
55
6484-6494
2016
Thermotoga maritima (Q9X0C8 and Q9X0C6), Thermotoga maritima ATCC 43589 (Q9X0C8 and Q9X0C6)
Amaro, R.E.; Myers, R.S.; Davisson, V.J.; Luthey-Schulten, Z.A.
Structural elements in IGP synthase exclude water to optimize ammonia transfer
Biophys. J.
89
475-487
2005
Saccharomyces cerevisiae (P33734), Saccharomyces cerevisiae ATCC 204508 (P33734)
Fujimori, K.; Ohta, D.
An Arabidopsis cDNA encoding a bifunctional glutamine amidotransferase/cyclase suppresses the histidine auxotrophy of a Saccharomyces cerevisiae his7 mutant
FEBS Lett.
428
229-234
1998
Arabidopsis thaliana (Q9SZ30), Arabidopsis thaliana
Lisi, G.; Currier, A.; Loria, J.
Glutamine hydrolysis by imidazole glycerol phosphate synthase displays temperature dependent allosteric activation
Front. Mol. Biosci.
5
4
2018
Thermotoga maritima (Q9X0C6 AND Q9X0C8), Thermotoga maritima (Q9X0C8 and Q9X0C6), Thermotoga maritima ATCC 43589 (Q9X0C6 AND Q9X0C8), Thermotoga maritima ATCC 43589 (Q9X0C8 and Q9X0C6)
Omi, R.; Mizuguchi, H.; Goto, M.; Miyahara, I.; Hayashi, H.; Kagamiyama, H.; Hirotsu, K.
Structure of imidazole glycerol phosphate synthase from Thermus thermophilus HB8 open-closed conformational change and ammonia tunneling
J. Biochem.
132
759-765
2002
Thermus thermophilus (Q7SIC0 AND Q7SIB9)
Beismann-Driemeyer, S.; Sterner, R.
Imidazole glycerol phosphate synthase from Thermotoga maritima. Quaternary structure, steady-state kinetics, and reaction mechanism of the bienzyme complex
J. Biol. Chem.
276
20387-20396
2001
Thermotoga maritima (Q9X0C6 AND Q9X0C8), Thermotoga maritima ATCC 43589 (Q9X0C6 AND Q9X0C8)
Lipchock, J.; Loria, J.P.
Millisecond dynamics in the allosteric enzyme imidazole glycerol phosphate synthase (IGPS) from Thermotoga maritima
J. Biomol. NMR
45
73-84
2009
Thermotoga maritima (Q9X0C6 AND Q9X0C8), Thermotoga maritima ATCC 43589 (Q9X0C6 AND Q9X0C8)
Lisi, G.P.; East, K.W.; Batista, V.S.; Loria, J.P.
Altering the allosteric pathway in IGPS suppresses millisecond motions and catalytic activity
Proc. Natl. Acad. Sci. USA
114
E3414-E3423
2017
Thermotoga maritima (Q9X0C8 and Q9X0C6)
Chittur, S.V.; Chen, Y.; Davisson, V.J.
Expression and purification of imidazole glycerol phosphate synthase from Saccharomyces cerevisiae
Protein Expr. Purif.
18
366-377
2000
Saccharomyces cerevisiae (P33734), Saccharomyces cerevisiae ATCC 204508 (P33734)
Liebold, C.; List, F.; Kalbitzer, H.R.; Sterner, R.; Brunner, E.
The interaction of ammonia and xenon with the imidazole glycerol phosphate synthase from Thermotoga maritima as detected by NMR spectroscopy
Protein Sci.
19
1774-1782
2010
Thermotoga maritima (Q9X0C6 AND Q9X0C8), Thermotoga maritima ATCC 43589 (Q9X0C6 AND Q9X0C8)
Holinski, A.; Heyn, K.; Merkl, R.; Sterner, R.
Combining ancestral sequence reconstruction with protein design to identify an interface hotspot in a key metabolic enzyme complex
Proteins
85
312-321
2017
Pyrobaculum arsenaticum (A4WHB6 AND A4WHA5), Zymomonas mobilis (Q5NMD6 AND Q5NMD4), Pyrobaculum arsenaticum DSM 13514 (A4WHB6 AND A4WHA5), Zymomonas mobilis ZM4 (Q5NMD6 AND Q5NMD4)
Douangamath, A.; Walker, M.; Beismann-Driemeyer, S.; Vega-Fernandez, M.C.; Sterner, R.; Wilmanns, M.
Structural evidence for ammonia tunneling across the (beta alpha)(8) barrel of the imidazole glycerol phosphate synthase bienzyme complex
Structure
10
185-193
2002
Thermotoga maritima (Q9X0C6 AND Q9X0C8), Thermotoga maritima ATCC 43589 (Q9X0C6 AND Q9X0C8)
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