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Information on EC 4.3.1.4 - formimidoyltetrahydrofolate cyclodeaminase and Organism(s) Gallus gallus and UniProt Accession Q9YH58

for references in articles please use BRENDA:EC4.3.1.4
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EC Tree
     4 Lyases
         4.3 Carbon-nitrogen lyases
             4.3.1 Ammonia-lyases
                4.3.1.4 formimidoyltetrahydrofolate cyclodeaminase
IUBMB Comments
In eukaroytes, occurs as a bifunctional enzyme that also has glutamate formimidoyltransferase (EC 2.1.2.5) activity.
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This record set is specific for:
Gallus gallus
UNIPROT: Q9YH58
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Word Map
The taxonomic range for the selected organisms is: Gallus gallus
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
formiminotransferase cyclodeaminase, 58k golgi protein, formiminotetrahydrofolate cyclodeaminase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
deaminase, formiminotetrahydrofolate cyclo-
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-
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formimino-THF cyclodeaminase
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-
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Formiminotetrahydrofolate cyclodeaminase
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formiminotransferase cyclodeaminase
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FTCD
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-
PATHWAY SOURCE
PATHWAYS
-
-, -, -
SYSTEMATIC NAME
IUBMB Comments
5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing; 5,10-methenyltetrahydrofolate-forming)
In eukaroytes, occurs as a bifunctional enzyme that also has glutamate formimidoyltransferase (EC 2.1.2.5) activity.
CAS REGISTRY NUMBER
COMMENTARY hide
9032-05-7
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
5-formiminotetrahydrofolate
5,10-methenyltetrahydrofolate + NH3
show the reaction diagram
-
-
?
5-formiminotetrahydrofolate
?
show the reaction diagram
-
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
5-formiminotetrahydrofolate
?
show the reaction diagram
-
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
Uniprot
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
isoform of the formiminotransferase cyclodeaminase enzyme complex
Manually annotated by BRENDA team
isoforms of the formiminotransferase cyclodeaminase enzyme complex
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
Golgi apparatus, formiminotransferase-cyclodeaminase enzyme complex
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
FTCD_CHICK
541
0
59154
Swiss-Prot
other Location (Reliability: 1)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
59100
8 * 59100, calculation from sequence of amono acid, isoform of formiminotransferase-cyclodeaminase enzyme complex
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
octamer
8 * 59100, calculation from sequence of amono acid, isoform of formiminotransferase-cyclodeaminase enzyme complex
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hennig, D.; Scales, S.J.; Moreau, A.; Murley, L.L.; De Mey, J.; Kreis, T.E.
A formiminotransferase cyclodeaminase isoform is localized to the Golgi complex and can mediate interaction of trans-Golgi network-derived vesicles with microtubules
J. Biol. Chem.
273
19602-19611
1998
Canis lupus familiaris, Canis lupus familiaris Madin-Darby, Gallus gallus (Q9YH58), Gallus gallus, Homo sapiens, Meleagris gallopavo, Rattus norvegicus, Sus scrofa (P53603)
Manually annotated by BRENDA team