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Information on EC 4.3.1.16 - threo-3-hydroxy-L-aspartate ammonia-lyase

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EC Tree
     4 Lyases
         4.3 Carbon-nitrogen lyases
             4.3.1 Ammonia-lyases
                4.3.1.16 threo-3-hydroxy-L-aspartate ammonia-lyase
IUBMB Comments
A pyridoxal-phosphate protein. The enzyme, purified from the bacterium Pseudomonas sp. T62, is highly specific, and does not accept any other stereoisomer of 3-hydroxyaspartate. Different from EC 4.3.1.20, erythro-3-hydroxy-L-aspartate ammonia-lyase and EC 4.3.1.27, threo-3-hydroxy-D-aspartate ammonia-lyase. Requires a divalent cation such as Mn2+, Mg2+, or Ca2+.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
D-THA DH, D-threo-3-hydroxyaspartate dehydratase, L-THA DH, L-threo-3-hydroxyaspartate dehydratase, threo-3-hydroxyaspartate ammonia-lyase, threo-3-hydroxyaspartate dehydratase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
threo-3-hydroxy-L-aspartate = oxaloacetate + NH3
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