Information on EC 4.2.3.93 - delta-guaiene synthase

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EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.93 delta-guaiene synthase
IUBMB Comments
Requires Mg2+. In Aquilaria crassna three clones of the enzyme gave about 80% delta-guaiene and 20% alpha-guaiene (see also EC 4.2.3.87). A fourth clone gave 54% delta-guaiene and 45% alpha-guaiene . The enzyme from Pogostemon cablin gives 13% delta-guaiene as well as 37% (-)-patchoulol (see EC 4.2.3.70), 13% alpha-guaiene (see EC 4.2.3.87), and traces of at least ten other sesquiterpenoids .
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The enzyme appears in viruses and cellular organisms
Synonyms
ACC2, delta-guaiene synthase 1, TPS, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2E,6E)-farnesyl diphosphate = delta-guaiene + diphosphate
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