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Information on EC 4.2.3.77 - (+)-germacrene D synthase

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EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.77 (+)-germacrene D synthase
IUBMB Comments
Requires Mg2+, Mn2+, Ni2+ or Co2+. The formation of (+)-germacrene D involves a 1,2-hydride shift whereas for (-)-germacrene D there is a 1,3-hydride shift (see EC 4.2.3.75).
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The enzyme appears in viruses and cellular organisms
Synonyms
GDS, GDS1, Sc11, TPS2, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2E,6E)-farnesyl diphosphate = (+)-germacrene D + diphosphate
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
-
-
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