Information on EC 4.2.3.42 - aphidicolan-16beta-ol synthase

for references in articles please use BRENDA:EC4.2.3.42
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.42 aphidicolan-16beta-ol synthase
IUBMB Comments
This is a bifunctional enzyme which also has EC 5.5.1.14 syn-copalyl diphosphate synthase activity. Aphidicolan-16beta-ol is a precursor of aphidicolin, a specific inhibitor of DNA polymerase alpha (EC 2.7.7.7).
Specify your search results
Select one or more organisms in this record: ?
The expected taxonomic range for this enzyme is: Rosellinia necatrix
Synonyms
ACS, PbACS, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
9alpha-copalyl diphosphate + H2O = aphidicolan-16beta-ol + diphosphate
show the reaction diagram
Select items on the left to see more content.