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Information on EC 4.2.3.34 - stemod-13(17)-ene synthase and Organism(s) Oryza sativa and UniProt Accession Q1AHB2

for references in articles please use BRENDA:EC4.2.3.34
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EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.34 stemod-13(17)-ene synthase
IUBMB Comments
This enzyme catalyses the committed step in the biosynthesis of the stemodane family of diterpenoid secondary metabolites, some of which possess mild antiviral activity. The enzyme also produces stemod-12-ene and stemar-13-ene as minor products.
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This record set is specific for:
Oryza sativa
UNIPROT: Q1AHB2
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Word Map
The taxonomic range for the selected organisms is: Oryza sativa
The expected taxonomic range for this enzyme is: Oryza
Synonyms
osksl11, ksl11, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SYSTEMATIC NAME
IUBMB Comments
9alpha-copalyl-diphosphate diphosphate-lyase [stemod-13(17)-ene-forming]
This enzyme catalyses the committed step in the biosynthesis of the stemodane family of diterpenoid secondary metabolites, some of which possess mild antiviral activity. The enzyme also produces stemod-12-ene and stemar-13-ene as minor products.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
9alpha-copalyl diphosphate
stemod-13(17)-ene + diphosphate
show the reaction diagram
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
9alpha-copalyl diphosphate
stemod-13(17)-ene + diphosphate
show the reaction diagram
the enzyme catalyzes the committed step in biosynthesis of the stemodane family of diterpenoid natural products, some of which possess antiviral activity
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
subsp. japonica
SwissProt
Manually annotated by BRENDA team
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Morrone, D.; Jin, Y.; Xu, M.; Choi, S.Y.; Coates, R.M.; Peters, R.J.
An unexpected diterpene cyclase from rice: functional identification of a stemodene synthase
Arch. Biochem. Biophys.
448
133-140
2006
Oryza sativa (Q1AHB2), Oryza sativa
Manually annotated by BRENDA team