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Information on EC 4.2.3.32 - levopimaradiene synthase

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EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.32 levopimaradiene synthase
IUBMB Comments
In Ginkgo, the enzyme catalyses the initial cyclization step in the biosynthesis of ginkgolides, a structurally unique family of diterpenoids that are highly specific platelet-activating-factor receptor antagonists . Levopimaradiene is widely distributed in higher plants. In some species the enzyme also forms abietadiene, palustradiene, and neoabietadiene .
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
levopimaradiene/abietadiene synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(+)-copalyl diphosphate = abieta-8(14),12-diene + diphosphate
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