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IUBMB Comments A sesterterpenoid synthase enzyme isolated from the bacterium Streptomyces somaliensis . The enzyme also produces somaliensene A (cf . EC 4.2.3.216 , somaliensene A synthase).
The expected taxonomic range for this enzyme is: Streptomyces somaliensis
Synonyms sesterterpene cyclase, stsC , more
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sesterterpene cyclase
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sesterterpene cyclase
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stsC
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geranylfarnesyl diphosphate = (-)-somaliensene B + diphosphate
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geranylfarnesyl-diphosphate diphosphate-lyase (cyclizing, (-)-somaliensene B-forming)
A sesterterpenoid synthase enzyme isolated from the bacterium Streptomyces somaliensis. The enzyme also produces somaliensene A (cf. EC 4.2.3.216, somaliensene A synthase).
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geranylfarnesyl diphosphate
somaliensene B + diphosphate
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geranylfarnesyl diphosphate
somaliensene B + diphosphate
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geranylfarnesyl diphosphate
somaliensene B + diphosphate
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Substrates: the enzyme also produces somaliensene A from geranylfarnesyl diphosphate Products: -
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additional information
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Substrates: the enzyme also produces somaliensene A from geranylfarnesyl diphosphate Products: -
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geranylfarnesyl diphosphate
somaliensene B + diphosphate
geranylfarnesyl diphosphate
somaliensene B + diphosphate
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Substrates: - Products: -
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geranylfarnesyl diphosphate
somaliensene B + diphosphate
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Substrates: - Products: -
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Mg2+
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5 mM used in assay conditions
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STSC_STRE0
Streptomyces somaliensis (strain ATCC 33201 / DSM 40738 / JCM 12659 / KCTC 9044 / NCTC 11332 / NRRL B-12077 / IP 733)
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0
33833
Swiss-Prot
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Yang, Y.; Zhang, Y.; Zhang, S.; Chen, Q.; Ma, K.; Bao, L.; Tao, Y.; Yin, W.; Wang, G.; Liu, H.
Identification and characterization of a membrane-bound sesterterpene cyclase from Streptomyces somaliensis
J. Nat. Prod.
81
1089-1092
2018
Streptomyces somaliensis, Streptomyces somaliensis ATCC 33201
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