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IUBMB CommentsRequires Mg2+. Characterized from the marine bacterium Saprospira grandis.
The expected taxonomic range for this enzyme is: Saprospira grandis
Synonyms
SapTC1, more
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SapTC1

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geranylgeranyl diphosphate + H2O = neoverrucosan-5beta-ol + diphosphate
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geranylgeranyl- diphosphate diphosphate-lyase (neoverrucosan-5beta-ol-forming)
Requires Mg2+. Characterized from the marine bacterium Saprospira grandis.
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geranylgeranyl diphosphate + H2O
neoverrucosan-5beta-ol + diphosphate
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Substrates: -
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geranylgeranyl diphosphate + H2O
neoverrucosan-5beta-ol + diphosphate
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Substrates: -
Products: -
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Mg2+
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presence of Mg2+ is required
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EDTA
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2.5 mM, complete loss of activity
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brenda
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brenda
Highest Expressing Human Cell Lines
Cell Line Links
Gene Links
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expression in Escherichia coli
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Yang, Y.; Zhang, S.; Ma, K.; Xu, Y.; Tao, Q.; Chen, Y.; Chen, J.; Guo, S.; Ren, J.; Wang, W.; Tao, Y.; Yin, W.; Liu, H.
Discovery and characterization of a new family of diterpene cyclases in bacteria and fungi
Angew. Chem. Int. Ed. Engl.
56
4749-4752
2017
Saprospira grandis
brenda
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