Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 4.2.3.19 - ent-kaurene synthase and Organism(s) Oryza sativa and UniProt Accession Q0JA82

for references in articles please use BRENDA:EC4.2.3.19
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.19 ent-kaurene synthase
IUBMB Comments
Part of a bifunctional enzyme involved in the biosynthesis of ent-kaurene. See also EC 5.5.1.13 (ent-copalyl diphosphate synthase)
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Oryza sativa
UNIPROT: Q0JA82
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The taxonomic range for the selected organisms is: Oryza sativa
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
ent-kaurene synthase, ppcps/ks, kaurene synthase, cps/ks, ent-kaurene synthase b, ent-ks, ent-copalyl/ent-kaurene synthase, bifunctional cps/ks, ent-kaur-16-ene synthase, ent-copalyldiphosphate synthase/ent-kaurene synthase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ent-beyerene synthase
-
-
ent-kaurene synthase B
-
-
-
-
ent-kaurene synthase like 2
-
-
ent-kaurene synthetase B
-
-
-
-
KSL2
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
cyclization
-
-
-
-
diphosphate lysis
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-kaurene-forming)
Part of a bifunctional enzyme involved in the biosynthesis of ent-kaurene. See also EC 5.5.1.13 (ent-copalyl diphosphate synthase)
CAS REGISTRY NUMBER
COMMENTARY hide
9055-64-5
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
8beta-hydroxy-ent-copalyl diphosphate
ent-13-epi-manoyl oxide + ent-kaurene + diphosphate
show the reaction diagram
-
-
-
-
?
ent-copalyl diphosphate
ent-beyerene + ent-kaurene + diphosphate
show the reaction diagram
-
-
-
-
?
ent-copalyl diphosphate
ent-kaurene + diphosphate
show the reaction diagram
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ent-copalyl diphosphate
ent-beyerene + ent-kaurene + diphosphate
show the reaction diagram
-
-
-
-
?
ent-copalyl diphosphate
ent-kaurene + diphosphate
show the reaction diagram
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
additional information
-
expression of KS4, KS7, and KS8 is induced by elicitor treatment
-
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
-
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
-
the enzyme is involved in defense mechanisms in rice roots
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
-
construction of transgenic rice mutants expressing mutated KS-like genes, the mutant plants show reduced enzyme activity, phenotype analysis and effects on gibberellin metabolism, overview
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
glutathione-affinity column chromatography
-
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
DNA and amino acid sequence determination of genes KS1-9, chromosomal localizations, gene KS9 is a pseudogene, phylogenetic analysis, overview
-
expressed in Escherichia coli BL21 cells
-
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
kaurene synthase-like 2 is drastically induced in roots by 0.1 mM methyl jasmonate treatment
-
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sakamoto, T.; Miura, K.; Itoh, H.; Tatsumi, T.; Ueguchi-Tanaka, M.; Ishiyama, K.; Kobayashi, M.; Agrawal, G.K.; Takeda, S.; Abe, K.; Miyao, A.; Hirochika, H.; Kitano, H.; Ashikari, M.; Matsuoka, M.
An overview of gibberellin metabolism enzyme genes and their related mutants in rice
Plant Physiol.
134
1642-1653
2004
Oryza sativa
Manually annotated by BRENDA team
Hayashi, Y.; Toyomasu, T.; Hirose, Y.; Onodera, Y.; Mitsuhashi, W.; Yamane, H.; Sassa, T.; Dairi, T.
Comparison of the enzymatic properties of ent-copalyl diphosphate-synthases in the biosynthesis of phytoalexins and gibberellins in rice
Biosci. Biotechnol. Biochem.
72
523-530
2008
Oryza sativa
Manually annotated by BRENDA team
Tezuka, D.; Ito, A.; Mitsuhashi, W.; Toyomasu, T.; Imai, R.
The rice ent-kaurene synthase like 2 encodes a functional ent-beyerene synthase
Biochem. Biophys. Res. Commun.
460
766-771
2015
Oryza sativa
Manually annotated by BRENDA team
Mafu, S.; Potter, K.C.; Hillwig, M.L.; Schulte, S.; Criswell, J.; Peters, R.J.
Efficient heterocyclisation by (di)terpene synthases
Chem. Commun. (Camb.)
51
13485-13487
2015
Arabidopsis thaliana, Fusarium fujikuroi (S0EA85), Fusarium fujikuroi CBS 195.34 / IMI 58289 / NRRL A-6831 (S0EA85), Oryza sativa, Physcomitrium patens, Physcomitrium patens (A5A8G0), Sinorhizobium fredii
Manually annotated by BRENDA team