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Information on EC 4.2.3.187 - (2Z,6E)-hedycaryol synthase

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EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.187 (2Z,6E)-hedycaryol synthase
IUBMB Comments
Isolated from the bacterium Kitasatospora setae. The stereochemistry suggests the farnesyl diphosphate rearranges to nerolidyl diphosphate or an equivalent intermediate before cyclization. See also EC 4.2.3.174 (2E,6E)-hedycaryol synthase.
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The expected taxonomic range for this enzyme is: Kitasatospora setae
Synonyms
HCS, KSE_00200t, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2E,6E)-farnesyl diphosphate + H2O = (2Z,6E)-hedycaryol + diphosphate
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