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EC Tree
IUBMB Comments The enzyme, found in the bacterium Streptosporangium roseum, is specific for (2E,6E)-farnesyl diphosphate.
The expected taxonomic range for this enzyme is: Streptosporangium roseum
Synonyms
epi-cubebol synthase,
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epi-cubebol synthase
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epi-cubebol synthase
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(2E,6E)-farnesyl diphosphate + H2O = 4-epi-cubebol + diphosphate
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(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 4-epi-cubebol-forming)
The enzyme, found in the bacterium Streptosporangium roseum, is specific for (2E,6E)-farnesyl diphosphate.
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(2E,6E)-farnesyl diphosphate + H2O
4-epi-cubebol + diphosphate
additional information
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(2E,6E)-farnesyl diphosphate + H2O
4-epi-cubebol + diphosphate
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(2E,6E)-farnesyl diphosphate + H2O
4-epi-cubebol + diphosphate
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no activity with geranyl diphosphate and geranylgeranyl diphosphate
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(2E,6E)-farnesyl diphosphate + H2O
4-epi-cubebol + diphosphate
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(2E,6E)-farnesyl diphosphate + H2O
4-epi-cubebol + diphosphate
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no activity with geranyl diphosphate and geranylgeranyl diphosphate
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additional information
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product determination and identification by EIMS fragmentation and MS spectrometry, overview. Analysis of different cyclization products from farnesyl diphosphate by action of different enzymes
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additional information
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product determination and identification by EIMS fragmentation and MS spectrometry, overview. Analysis of different cyclization products from farnesyl diphosphate by action of different enzymes
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Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
(2E,6E)-farnesyl diphosphate + H2O
4-epi-cubebol + diphosphate
(2E,6E)-farnesyl diphosphate + H2O
4-epi-cubebol + diphosphate
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?
(2E,6E)-farnesyl diphosphate + H2O
4-epi-cubebol + diphosphate
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UniParc: UPI0005B99664
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UniParc: UPI0005B99664
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ECUB_STRRD
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
330
0
37807
Swiss-Prot
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expression in Escherichia coli BL21
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recombinant enzyme expression in Escherichia coli strain BL21
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Rabe, P.; Schmitz, T.; Dickschat, J.S.
Mechanistic investigations on six bacterial terpene cyclases
Beilstein J. Org. Chem.
12
1839-1850
2016
Streptosporangium roseum, Streptosporangium roseum DSM 43021
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Rabe, P.; Dickschat, J.S.
The EIMS fragmentation mechanisms of the sesquiterpenes corvol ethers A and B, epi-cubebol and isodauc-8-en-11-ol
Beilstein J. Org. Chem.
12
1380-1394
2016
Streptosporangium roseum, Streptosporangium roseum DSM 43021
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