Information on EC 4.2.3.161 - (3S)-(+)-asterisca-2(9),6-diene synthase

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The expected taxonomic range for this enzyme is: Dictyostelium discoideum

EC NUMBER
COMMENTARY hide
4.2.3.161
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RECOMMENDED NAME
GeneOntology No.
(3S)-(+)-asterisca-2(9),6-diene synthase
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SYSTEMATIC NAME
IUBMB Comments
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (3S)-(+)-asterisca-2(9),6-diene-forming)
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
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one possible function of volatile terpenes emitted from Dictyostelium discoideum is to attract other organisms to facilitate spore dispersal, resembling the function of volatile terpenes from the fruiting bodies of fungi
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2E,6E)-farnesyl diphosphate
(3S)-(+)-asterisca-2(9),6-diene + diphosphate
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(2E,6E)-farnesyl diphosphate
(3S)-(+)-asterisca-2(9),6-diene + diphosphate
show the reaction diagram
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-
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?
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli
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heterologously expressed in Escherichia coli
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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
terpene synthase genes of Dictyostelium discoideum are expressed at different times during multicellular development. As Dictyostelium discoideum begins to starve (0 h), mRNA of DdTPS2 is present at detectable but low levels. The mRNA abundance increases during development. At the time of slug formation (approximately 16 h), DdTPS2 mRNA reaches its highest abundance
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terpene synthase genes of Dictyostelium discoideum are expressed at different times during multicellular development. during culmination (from 18 to 24 h), DdTPS2 level decreases
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