Information on EC 4.2.3.160 - (2S,3R,6S,9S)-(-)-protoillud-7-ene synthase

for references in articles please use BRENDA:EC4.2.3.160
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The expected taxonomic range for this enzyme is: Dictyostelium discoideum

EC NUMBER
COMMENTARY hide
4.2.3.160
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RECOMMENDED NAME
GeneOntology No.
(2S,3R,6S,9S)-(-)-protoillud-7-ene synthase
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SYSTEMATIC NAME
IUBMB Comments
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (2S,3R,6S,9S)-(-)-protoillud-7-ene-forming)
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
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one possible function of volatile terpenes emitted from Dictyostelium discoideum is to attract other organisms to facilitate spore dispersal, resembling the function of volatile terpenes from the fruiting bodies of fungi
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2E,6E)-farnesyl diphosphate
(2S,3R,6S,9S)-(-)-protoillud-7-ene + diphosphate
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(2E,6E)-farnesyl diphosphate
(2S,3R,6S,9S)-(-)-protoillud-7-ene + diphosphate
show the reaction diagram
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one possible function of volatile terpenes emitted from Dictyostelium discoideum is to attract other organisms to facilitate spore dispersal, resembling the function of volatile terpenes from the fruiting bodies of fungi
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-
?
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
heterologously expressed in Escherichia coli
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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
each terpene synthase gene of Dictyostelium discoideum is expressed at different times during multicellular development. As Dictyostelium discoideum begins to starve (0 h), mRNA of DdTPS6 is present at detectable but low level. The mRNA abundance increases during development. During culmination (from 18 to 24 h) DdTPS6 mRNA accumulates to higher levels, reaching a peaks at the ultimate stage of mature fruiting body (24 h)
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