show all | hide all No of entries

Information on EC 4.2.3.156 - hydroxysqualene synthase

for references in articles please use BRENDA:EC4.2.3.156
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.156 hydroxysqualene synthase
IUBMB Comments
This enzyme, isolated from the bacteria Rhodopseudomonas palustris and Zymomonas mobilis, participates, along with EC 2.5.1.103, presqualene diphosphate synthase, and EC 1.17.8.1, hydroxysqualene dehydroxylase, in the conversion of all-trans-farnesyl diphosphate to squalene. Eukaryotes achieve the same goal in a single step, catalysed by EC 2.5.1.21, squalene synthase.
Specify your search results
Select one or more organisms in this record: ?
The enzyme appears in viruses and cellular organisms
Synonyms
Acel_1693, hpnC, RPA3743, ZMO0869, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
presqualene diphosphate + H2O = hydroxysqualene + diphosphate
show the reaction diagram
-
-
-
-
PATHWAY SOURCE
PATHWAYS
Select items on the left to see more content.