Information on EC 4.2.3.111 - (-)-alpha-terpineol synthase

for references in articles please use BRENDA:EC4.2.3.111
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The expected taxonomic range for this enzyme is: Vitis vinifera

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EC NUMBER
COMMENTARY hide
4.2.3.111
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RECOMMENDED NAME
GeneOntology No.
(-)-alpha-terpineol synthase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
geranyl diphosphate + H2O = (-)-alpha-terpineol + diphosphate
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Monoterpenoid biosynthesis
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Metabolic pathways
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Biosynthesis of secondary metabolites
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SYSTEMATIC NAME
IUBMB Comments
geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-alpha-terpineol-forming]
The enzyme has been characterized from Vitis vinifera (grape). Also forms some 1,8-cineole and traces of other monoterpenoids.
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
geranyl diphosphate
(-)-alpha-terpineol + diphosphate
show the reaction diagram
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products are 50.1% (-)-alpha-terpineol, 11.8% 1,8-cineole, 8.5% (+)-beta-pinene, plus lower amounts of additional monoterpenes
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?
additional information
?
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pI VALUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5.9
calculated
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
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strongest signals with RNA from flower buds and strongly reduced transcript levels in pre- and postanthesis open flowers and in set flowers at early fruit onset
Manually annotated by BRENDA team
additional information
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expression appears restricted to flowers
Manually annotated by BRENDA team
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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
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LINKS TO OTHER DATABASES (specific for EC-Number 4.2.3.111)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
InterPro (database of protein families, domains and functional sites)