Information on EC 4.2.1.56 - Itaconyl-CoA hydratase
for references in articles please use BRENDA:EC4.2.1.56Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
The enzyme appears in viruses and cellular organisms
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Citramalyl-CoA = itaconyl-CoA + H2O
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
itaconate degradation
-
-
C5-Branched dibasic acid metabolism
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Hydratase, itaconyl coenzyme A
-
-
-
-
Itaconyl coenzyme A hydratase
-
-
-
-
Itaconyl-CoA hydratase
-
-
-
-
ICH

-
-
RipB

-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
-
brenda
-
-
-
brenda
-
-
-
brenda
-
-
-
brenda
-
-
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
(S)-citramalyl-CoA
itaconyl-CoA + H2O
itaconyl-CoA + H2O
(S)-citramalyl-CoA
Itaconyl-CoA + H2O
Citramalyl-CoA
mesaconyl-C4-CoA + H2O
itaconyl-CoA
(S)-citramalyl-CoA

itaconyl-CoA + H2O
-
-
-
-
r
(S)-citramalyl-CoA
itaconyl-CoA + H2O
-
-
-
-
r
(S)-citramalyl-CoA
itaconyl-CoA + H2O
-
-
-
-
r
(S)-citramalyl-CoA
itaconyl-CoA + H2O
-
-
-
-
r
itaconyl-CoA + H2O

(S)-citramalyl-CoA
-
-
-
-
r
itaconyl-CoA + H2O
(S)-citramalyl-CoA
-
-
-
-
r
itaconyl-CoA + H2O
(S)-citramalyl-CoA
-
-
-
-
r
itaconyl-CoA + H2O
(S)-citramalyl-CoA
-
-
-
-
r
Itaconyl-CoA + H2O

?
-
enzyme is involved in itaconate catabolism
-
-
-
Itaconyl-CoA + H2O
?
-
enzyme is involved in itaconate catabolism
-
-
-
Itaconyl-CoA + H2O

Citramalyl-CoA
-
-
-
-
Itaconyl-CoA + H2O
Citramalyl-CoA
-
-
-
-
mesaconyl-C4-CoA + H2O

itaconyl-CoA
-
-
-
-
r
mesaconyl-C4-CoA + H2O
itaconyl-CoA
-
-
-
-
r
mesaconyl-C4-CoA + H2O
itaconyl-CoA
-
-
-
-
r
mesaconyl-C4-CoA + H2O
itaconyl-CoA
-
-
-
-
r
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
itaconyl-CoA + H2O
(S)-citramalyl-CoA
itaconyl-CoA + H2O

(S)-citramalyl-CoA
-
-
-
-
r
itaconyl-CoA + H2O
(S)-citramalyl-CoA
-
-
-
-
r
itaconyl-CoA + H2O
(S)-citramalyl-CoA
-
-
-
-
r
itaconyl-CoA + H2O
(S)-citramalyl-CoA
-
-
-
-
r
Itaconyl-CoA + H2O

?
-
enzyme is involved in itaconate catabolism
-
-
-
Itaconyl-CoA + H2O
?
-
enzyme is involved in itaconate catabolism
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
additional information

-
the enzyme does not require divalent metal ions
additional information
-
the enzyme does not require divalent metal ions
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.14 - 0.49
(S)-citramalyl-CoA
0.034 - 0.12
itaconyl-CoA
0.31 - 0.51
mesaconyl-C4-CoA
0.14
(S)-citramalyl-CoA

-
at pH 7.5 and 45°C
0.49
(S)-citramalyl-CoA
-
at pH 7.5 and 45°C
0.034
itaconyl-CoA

-
at pH 7.5 and 45°C
0.12
itaconyl-CoA
-
at pH 7.5 and 45°C
0.31
mesaconyl-C4-CoA

-
at pH 7.5 and 45°C
0.51
mesaconyl-C4-CoA
-
at pH 7.5 and 45°C
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
4.4 - 415.4
(S)-citramalyl-CoA
98.8 - 4651
mesaconyl-C4-CoA
4.4
(S)-citramalyl-CoA

-
at pH 7.5 and 45°C
415.4
(S)-citramalyl-CoA
-
at pH 7.5 and 45°C
52.2
itaconyl-CoA

-
at pH 7.5 and 45°C
415
itaconyl-CoA
-
at pH 7.5 and 45°C
98.8
mesaconyl-C4-CoA

-
at pH 7.5 and 45°C
4651
mesaconyl-C4-CoA
-
at pH 7.5 and 45°C
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli BL21(DE3) cells

-
expressed in Escherichia coli BL21(DE3) cells
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
AUHM_HUMAN
339
35609
Swiss-Prot
AUHM_MOUSE
314
33395
Swiss-Prot
AUHM_RAT
315
33341
Swiss-Prot
A0A1U9MFU8_9RHIZ
285
32220
TrEMBL
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Cooper, R.A.; Kornberg, H.L.
The utilization of itaconate by Pseudomonas sp.
Biochem. J.
91
82-91
1964
Pseudomonas sp.
brenda
Sasikaran, J.; Ziemski, M.; Zadora, P.K.; Fleig, A.; Berg, I.A.
Bacterial itaconate degradation promotes pathogenicity
Nat. Chem. Biol.
10
371-377
2014
Pseudomonas aeruginosa, Pseudomonas aeruginosa PA0878, Yersinia pestis, Yersinia pestis Y2384
brenda
html completed