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Information on EC 4.2.1.2 - fumarate hydratase and Organism(s) Rickettsia prowazekii and UniProt Accession Q9ZCQ4

for references in articles please use BRENDA:EC4.2.1.2
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EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.2 fumarate hydratase
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This record set is specific for:
Rickettsia prowazekii
UNIPROT: Q9ZCQ4 not found.
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Word Map
The taxonomic range for the selected organisms is: Rickettsia prowazekii
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
Synonyms
fumarase, fumarate hydratase, fumarase c, class ii fumarase, lmfh-2, scfumc, slfumc, mmcbc, lmfh-1, stfumc, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
fumarate hydratase
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fumarase
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hydratase, fumarate
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L-malate hydro-lyase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
elimination
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SYSTEMATIC NAME
IUBMB Comments
(S)-malate hydro-lyase (fumarate-forming)
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CAS REGISTRY NUMBER
COMMENTARY hide
9032-88-6
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
homodimer
crystal structure
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
crystal structure solved at 2.4 A resolution. FumC crystallizes as a homodimer containing two subunits of the normally tetrameric enzyme, in which each chain forms an elongated central four-helix bundle capped by two compact domains at the N- and C-termini
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli as a His-tagged fusion protein
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Phan, I.; Subramanian, S.; Olsen, C.; Edwards, T.E.; Guo, W.; Zhang, Y.; Van Voorhis, W.C.; Stewart, L.J.; Myler, P.J.
Structure of fumarate hydratase from Rickettsia prowazekii, the agent of typhus and suspected relative of the mitochondria
Acta Crystallogr. Sect. F
67
1123-1128
2011
Rickettsia prowazekii (Q9ZCQ4), Rickettsia prowazekii
Manually annotated by BRENDA team