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Information on EC - enoyl-CoA hydratase 2

for references in articles please use BRENDA:EC4.2.1.119
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EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
       enoyl-CoA hydratase 2
IUBMB Comments
This enzyme catalyses a hydration step in peroxisomal beta-oxidation. The human multifunctional enzyme type 2 (MFE-2) is a 79000 Da enzyme composed of three functional units: (3R)-hydroxyacyl-CoA dehydrogenase, 2-enoyl-CoA hydratase 2 and sterol carrier protein 2-like units . The enzymes from Aeromonas caviae and Arabidopsis thaliana are monofunctional enzymes. 2-Enoyl-CoA hydratase 3 from Candida tropicalis is a part from multifunctional enzyme type 2 .
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
(3R)-hydroxyacyl-CoA dehydrogenase/2-enoyl-CoA hydratase 2, (R)-specific ECH, (R)-specific enoyl coenzyme A hydratase, (R)-specific enoyl-CoA hydratase, (R)-specific enoyl-coenzyme A hydratase, 2-enoyl-CoA hydratase, 2-enoyl-CoA hydratase 2, 2-enoyl-hydratase 2, 2E-enoyl-CoA hydratase 2, At1g76150, more
(3R)-3-hydroxyacyl-CoA = (2E)-2-enoyl-CoA + H2O
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