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Information on EC 4.1.2.51 - 2-dehydro-3-deoxy-D-gluconate aldolase

for references in articles please use BRENDA:EC4.1.2.51

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IUBMB Comments

The enzyme from the archaeon Picrophilus torridus is involved in D-glucose and D-galactose catabolism via the nonphosphorylative variant of the Entner-Doudoroff pathway. In the direction of aldol synthesis the enzyme catalyses the formation of 2-dehydro-3-deoxy-D-gluconate and 2-dehydro-3-deoxy-D-galactonate at a similar ratio. It shows no activity with 2-dehydro-3-deoxy-D-gluconate 6-phosphate. cf. EC 4.1.2.14, 2-dehydro-3-deoxy-phosphogluconate aldolase.

The expected taxonomic range for this enzyme is: Bacteria, Archaea

Synonyms
pto1279, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-dehydro-3-deoxy-D-gluconate = pyruvate + D-glyceraldehyde
show the reaction diagram
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